/* Generated by Cython 3.0.2 */

/* BEGIN: Cython Metadata
{
    "distutils": {
        "depends": [
            "/Users/runner/work/pysam/pysam/bcftools/bcftools.pysam.h",
            "/Users/runner/work/pysam/pysam/samtools/samtools.pysam.h"
        ],
        "extra_compile_args": [
            "-Wno-unused",
            "-Wno-strict-prototypes",
            "-Wno-sign-compare",
            "-Wno-error=declaration-after-statement"
        ],
        "include_dirs": [
            "/Users/runner/work/pysam/pysam/pysam",
            "/Users/runner/work/pysam/pysam/htslib",
            "/Users/runner/work/pysam/pysam/samtools",
            "/Users/runner/work/pysam/pysam/samtools/lz4",
            "/Users/runner/work/pysam/pysam/bcftools",
            "/Users/runner/work/pysam/pysam"
        ],
        "language": "c",
        "libraries": [
            "z",
            "lzma",
            "bz2",
            "z",
            "curl",
            "chtslib.cpython-39-darwin",
            "csamtools.cpython-39-darwin",
            "cbcftools.cpython-39-darwin"
        ],
        "library_dirs": [
            "/Users/runner/work/pysam/pysam/pysam",
            "/Users/runner/work/pysam/pysam"
        ],
        "name": "pysam.libcutils",
        "sources": [
            "pysam/libcutils.pyx",
            "pysam/pysam_util.c"
        ]
    },
    "module_name": "pysam.libcutils"
}
END: Cython Metadata */

#ifndef PY_SSIZE_T_CLEAN
#define PY_SSIZE_T_CLEAN
#endif /* PY_SSIZE_T_CLEAN */
#if defined(CYTHON_LIMITED_API) && 0
  #ifndef Py_LIMITED_API
    #if CYTHON_LIMITED_API+0 > 0x03030000
      #define Py_LIMITED_API CYTHON_LIMITED_API
    #else
      #define Py_LIMITED_API 0x03030000
    #endif
  #endif
#endif

#include "Python.h"

    #if PY_MAJOR_VERSION >= 3
      #define __Pyx_PyFloat_FromString(obj)  PyFloat_FromString(obj)
    #else
      #define __Pyx_PyFloat_FromString(obj)  PyFloat_FromString(obj, NULL)
    #endif
    

    #if PY_MAJOR_VERSION <= 2
    #define PyDict_GetItemWithError _PyDict_GetItemWithError
    #endif
    

    #if (PY_VERSION_HEX < 0x030700b1 || (CYTHON_COMPILING_IN_PYPY && PYPY_VERSION_NUM < 0x07030600)) && !defined(PyContextVar_Get)
    #define PyContextVar_Get(var, d, v)         ((d) ?             ((void)(var), Py_INCREF(d), (v)[0] = (d), 0) :             ((v)[0] = NULL, 0)         )
    #endif
    
#ifndef Py_PYTHON_H
    #error Python headers needed to compile C extensions, please install development version of Python.
#elif PY_VERSION_HEX < 0x02070000 || (0x03000000 <= PY_VERSION_HEX && PY_VERSION_HEX < 0x03030000)
    #error Cython requires Python 2.7+ or Python 3.3+.
#else
#if CYTHON_LIMITED_API
#define __PYX_EXTRA_ABI_MODULE_NAME "limited"
#else
#define __PYX_EXTRA_ABI_MODULE_NAME ""
#endif
#define CYTHON_ABI "3_0_2" __PYX_EXTRA_ABI_MODULE_NAME
#define __PYX_ABI_MODULE_NAME "_cython_" CYTHON_ABI
#define __PYX_TYPE_MODULE_PREFIX __PYX_ABI_MODULE_NAME "."
#define CYTHON_HEX_VERSION 0x030002F0
#define CYTHON_FUTURE_DIVISION 1
#include <stddef.h>
#ifndef offsetof
  #define offsetof(type, member) ( (size_t) & ((type*)0) -> member )
#endif
#if !defined(_WIN32) && !defined(WIN32) && !defined(MS_WINDOWS)
  #ifndef __stdcall
    #define __stdcall
  #endif
  #ifndef __cdecl
    #define __cdecl
  #endif
  #ifndef __fastcall
    #define __fastcall
  #endif
#endif
#ifndef DL_IMPORT
  #define DL_IMPORT(t) t
#endif
#ifndef DL_EXPORT
  #define DL_EXPORT(t) t
#endif
#define __PYX_COMMA ,
#ifndef HAVE_LONG_LONG
  #define HAVE_LONG_LONG
#endif
#ifndef PY_LONG_LONG
  #define PY_LONG_LONG LONG_LONG
#endif
#ifndef Py_HUGE_VAL
  #define Py_HUGE_VAL HUGE_VAL
#endif
#define __PYX_LIMITED_VERSION_HEX PY_VERSION_HEX
#if defined(GRAALVM_PYTHON)
  /* For very preliminary testing purposes. Most variables are set the same as PyPy.
     The existence of this section does not imply that anything works or is even tested */
  #define CYTHON_COMPILING_IN_PYPY 0
  #define CYTHON_COMPILING_IN_CPYTHON 0
  #define CYTHON_COMPILING_IN_LIMITED_API 0
  #define CYTHON_COMPILING_IN_GRAAL 1
  #define CYTHON_COMPILING_IN_NOGIL 0
  #undef CYTHON_USE_TYPE_SLOTS
  #define CYTHON_USE_TYPE_SLOTS 0
  #undef CYTHON_USE_TYPE_SPECS
  #define CYTHON_USE_TYPE_SPECS 0
  #undef CYTHON_USE_PYTYPE_LOOKUP
  #define CYTHON_USE_PYTYPE_LOOKUP 0
  #if PY_VERSION_HEX < 0x03050000
    #undef CYTHON_USE_ASYNC_SLOTS
    #define CYTHON_USE_ASYNC_SLOTS 0
  #elif !defined(CYTHON_USE_ASYNC_SLOTS)
    #define CYTHON_USE_ASYNC_SLOTS 1
  #endif
  #undef CYTHON_USE_PYLIST_INTERNALS
  #define CYTHON_USE_PYLIST_INTERNALS 0
  #undef CYTHON_USE_UNICODE_INTERNALS
  #define CYTHON_USE_UNICODE_INTERNALS 0
  #undef CYTHON_USE_UNICODE_WRITER
  #define CYTHON_USE_UNICODE_WRITER 0
  #undef CYTHON_USE_PYLONG_INTERNALS
  #define CYTHON_USE_PYLONG_INTERNALS 0
  #undef CYTHON_AVOID_BORROWED_REFS
  #define CYTHON_AVOID_BORROWED_REFS 1
  #undef CYTHON_ASSUME_SAFE_MACROS
  #define CYTHON_ASSUME_SAFE_MACROS 0
  #undef CYTHON_UNPACK_METHODS
  #define CYTHON_UNPACK_METHODS 0
  #undef CYTHON_FAST_THREAD_STATE
  #define CYTHON_FAST_THREAD_STATE 0
  #undef CYTHON_FAST_GIL
  #define CYTHON_FAST_GIL 0
  #undef CYTHON_METH_FASTCALL
  #define CYTHON_METH_FASTCALL 0
  #undef CYTHON_FAST_PYCALL
  #define CYTHON_FAST_PYCALL 0
  #ifndef CYTHON_PEP487_INIT_SUBCLASS
    #define CYTHON_PEP487_INIT_SUBCLASS (PY_MAJOR_VERSION >= 3)
  #endif
  #undef CYTHON_PEP489_MULTI_PHASE_INIT
  #define CYTHON_PEP489_MULTI_PHASE_INIT 1
  #undef CYTHON_USE_MODULE_STATE
  #define CYTHON_USE_MODULE_STATE 0
  #undef CYTHON_USE_TP_FINALIZE
  #define CYTHON_USE_TP_FINALIZE 0
  #undef CYTHON_USE_DICT_VERSIONS
  #define CYTHON_USE_DICT_VERSIONS 0
  #undef CYTHON_USE_EXC_INFO_STACK
  #define CYTHON_USE_EXC_INFO_STACK 0
  #ifndef CYTHON_UPDATE_DESCRIPTOR_DOC
    #define CYTHON_UPDATE_DESCRIPTOR_DOC 0
  #endif
#elif defined(PYPY_VERSION)
  #define CYTHON_COMPILING_IN_PYPY 1
  #define CYTHON_COMPILING_IN_CPYTHON 0
  #define CYTHON_COMPILING_IN_LIMITED_API 0
  #define CYTHON_COMPILING_IN_GRAAL 0
  #define CYTHON_COMPILING_IN_NOGIL 0
  #undef CYTHON_USE_TYPE_SLOTS
  #define CYTHON_USE_TYPE_SLOTS 0
  #ifndef CYTHON_USE_TYPE_SPECS
    #define CYTHON_USE_TYPE_SPECS 0
  #endif
  #undef CYTHON_USE_PYTYPE_LOOKUP
  #define CYTHON_USE_PYTYPE_LOOKUP 0
  #if PY_VERSION_HEX < 0x03050000
    #undef CYTHON_USE_ASYNC_SLOTS
    #define CYTHON_USE_ASYNC_SLOTS 0
  #elif !defined(CYTHON_USE_ASYNC_SLOTS)
    #define CYTHON_USE_ASYNC_SLOTS 1
  #endif
  #undef CYTHON_USE_PYLIST_INTERNALS
  #define CYTHON_USE_PYLIST_INTERNALS 0
  #undef CYTHON_USE_UNICODE_INTERNALS
  #define CYTHON_USE_UNICODE_INTERNALS 0
  #undef CYTHON_USE_UNICODE_WRITER
  #define CYTHON_USE_UNICODE_WRITER 0
  #undef CYTHON_USE_PYLONG_INTERNALS
  #define CYTHON_USE_PYLONG_INTERNALS 0
  #undef CYTHON_AVOID_BORROWED_REFS
  #define CYTHON_AVOID_BORROWED_REFS 1
  #undef CYTHON_ASSUME_SAFE_MACROS
  #define CYTHON_ASSUME_SAFE_MACROS 0
  #undef CYTHON_UNPACK_METHODS
  #define CYTHON_UNPACK_METHODS 0
  #undef CYTHON_FAST_THREAD_STATE
  #define CYTHON_FAST_THREAD_STATE 0
  #undef CYTHON_FAST_GIL
  #define CYTHON_FAST_GIL 0
  #undef CYTHON_METH_FASTCALL
  #define CYTHON_METH_FASTCALL 0
  #undef CYTHON_FAST_PYCALL
  #define CYTHON_FAST_PYCALL 0
  #ifndef CYTHON_PEP487_INIT_SUBCLASS
    #define CYTHON_PEP487_INIT_SUBCLASS (PY_MAJOR_VERSION >= 3)
  #endif
  #if PY_VERSION_HEX < 0x03090000
    #undef CYTHON_PEP489_MULTI_PHASE_INIT
    #define CYTHON_PEP489_MULTI_PHASE_INIT 0
  #elif !defined(CYTHON_PEP489_MULTI_PHASE_INIT)
    #define CYTHON_PEP489_MULTI_PHASE_INIT 1
  #endif
  #undef CYTHON_USE_MODULE_STATE
  #define CYTHON_USE_MODULE_STATE 0
  #undef CYTHON_USE_TP_FINALIZE
  #define CYTHON_USE_TP_FINALIZE (PY_VERSION_HEX >= 0x030400a1 && PYPY_VERSION_NUM >= 0x07030C00)
  #undef CYTHON_USE_DICT_VERSIONS
  #define CYTHON_USE_DICT_VERSIONS 0
  #undef CYTHON_USE_EXC_INFO_STACK
  #define CYTHON_USE_EXC_INFO_STACK 0
  #ifndef CYTHON_UPDATE_DESCRIPTOR_DOC
    #define CYTHON_UPDATE_DESCRIPTOR_DOC 0
  #endif
#elif defined(CYTHON_LIMITED_API)
  #ifdef Py_LIMITED_API
    #undef __PYX_LIMITED_VERSION_HEX
    #define __PYX_LIMITED_VERSION_HEX Py_LIMITED_API
  #endif
  #define CYTHON_COMPILING_IN_PYPY 0
  #define CYTHON_COMPILING_IN_CPYTHON 0
  #define CYTHON_COMPILING_IN_LIMITED_API 1
  #define CYTHON_COMPILING_IN_GRAAL 0
  #define CYTHON_COMPILING_IN_NOGIL 0
  #undef CYTHON_CLINE_IN_TRACEBACK
  #define CYTHON_CLINE_IN_TRACEBACK 0
  #undef CYTHON_USE_TYPE_SLOTS
  #define CYTHON_USE_TYPE_SLOTS 0
  #undef CYTHON_USE_TYPE_SPECS
  #define CYTHON_USE_TYPE_SPECS 1
  #undef CYTHON_USE_PYTYPE_LOOKUP
  #define CYTHON_USE_PYTYPE_LOOKUP 0
  #undef CYTHON_USE_ASYNC_SLOTS
  #define CYTHON_USE_ASYNC_SLOTS 0
  #undef CYTHON_USE_PYLIST_INTERNALS
  #define CYTHON_USE_PYLIST_INTERNALS 0
  #undef CYTHON_USE_UNICODE_INTERNALS
  #define CYTHON_USE_UNICODE_INTERNALS 0
  #ifndef CYTHON_USE_UNICODE_WRITER
    #define CYTHON_USE_UNICODE_WRITER 0
  #endif
  #undef CYTHON_USE_PYLONG_INTERNALS
  #define CYTHON_USE_PYLONG_INTERNALS 0
  #ifndef CYTHON_AVOID_BORROWED_REFS
    #define CYTHON_AVOID_BORROWED_REFS 0
  #endif
  #undef CYTHON_ASSUME_SAFE_MACROS
  #define CYTHON_ASSUME_SAFE_MACROS 0
  #undef CYTHON_UNPACK_METHODS
  #define CYTHON_UNPACK_METHODS 0
  #undef CYTHON_FAST_THREAD_STATE
  #define CYTHON_FAST_THREAD_STATE 0
  #undef CYTHON_FAST_GIL
  #define CYTHON_FAST_GIL 0
  #undef CYTHON_METH_FASTCALL
  #define CYTHON_METH_FASTCALL 0
  #undef CYTHON_FAST_PYCALL
  #define CYTHON_FAST_PYCALL 0
  #ifndef CYTHON_PEP487_INIT_SUBCLASS
    #define CYTHON_PEP487_INIT_SUBCLASS 1
  #endif
  #undef CYTHON_PEP489_MULTI_PHASE_INIT
  #define CYTHON_PEP489_MULTI_PHASE_INIT 0
  #undef CYTHON_USE_MODULE_STATE
  #define CYTHON_USE_MODULE_STATE 1
  #ifndef CYTHON_USE_TP_FINALIZE
    #define CYTHON_USE_TP_FINALIZE 0
  #endif
  #undef CYTHON_USE_DICT_VERSIONS
  #define CYTHON_USE_DICT_VERSIONS 0
  #undef CYTHON_USE_EXC_INFO_STACK
  #define CYTHON_USE_EXC_INFO_STACK 0
  #ifndef CYTHON_UPDATE_DESCRIPTOR_DOC
    #define CYTHON_UPDATE_DESCRIPTOR_DOC 0
  #endif
#elif defined(PY_NOGIL)
  #define CYTHON_COMPILING_IN_PYPY 0
  #define CYTHON_COMPILING_IN_CPYTHON 0
  #define CYTHON_COMPILING_IN_LIMITED_API 0
  #define CYTHON_COMPILING_IN_GRAAL 0
  #define CYTHON_COMPILING_IN_NOGIL 1
  #ifndef CYTHON_USE_TYPE_SLOTS
    #define CYTHON_USE_TYPE_SLOTS 1
  #endif
  #undef CYTHON_USE_PYTYPE_LOOKUP
  #define CYTHON_USE_PYTYPE_LOOKUP 0
  #ifndef CYTHON_USE_ASYNC_SLOTS
    #define CYTHON_USE_ASYNC_SLOTS 1
  #endif
  #undef CYTHON_USE_PYLIST_INTERNALS
  #define CYTHON_USE_PYLIST_INTERNALS 0
  #ifndef CYTHON_USE_UNICODE_INTERNALS
    #define CYTHON_USE_UNICODE_INTERNALS 1
  #endif
  #undef CYTHON_USE_UNICODE_WRITER
  #define CYTHON_USE_UNICODE_WRITER 0
  #undef CYTHON_USE_PYLONG_INTERNALS
  #define CYTHON_USE_PYLONG_INTERNALS 0
  #ifndef CYTHON_AVOID_BORROWED_REFS
    #define CYTHON_AVOID_BORROWED_REFS 0
  #endif
  #ifndef CYTHON_ASSUME_SAFE_MACROS
    #define CYTHON_ASSUME_SAFE_MACROS 1
  #endif
  #ifndef CYTHON_UNPACK_METHODS
    #define CYTHON_UNPACK_METHODS 1
  #endif
  #undef CYTHON_FAST_THREAD_STATE
  #define CYTHON_FAST_THREAD_STATE 0
  #undef CYTHON_FAST_PYCALL
  #define CYTHON_FAST_PYCALL 0
  #ifndef CYTHON_PEP489_MULTI_PHASE_INIT
    #define CYTHON_PEP489_MULTI_PHASE_INIT 1
  #endif
  #ifndef CYTHON_USE_TP_FINALIZE
    #define CYTHON_USE_TP_FINALIZE 1
  #endif
  #undef CYTHON_USE_DICT_VERSIONS
  #define CYTHON_USE_DICT_VERSIONS 0
  #undef CYTHON_USE_EXC_INFO_STACK
  #define CYTHON_USE_EXC_INFO_STACK 0
#else
  #define CYTHON_COMPILING_IN_PYPY 0
  #define CYTHON_COMPILING_IN_CPYTHON 1
  #define CYTHON_COMPILING_IN_LIMITED_API 0
  #define CYTHON_COMPILING_IN_GRAAL 0
  #define CYTHON_COMPILING_IN_NOGIL 0
  #ifndef CYTHON_USE_TYPE_SLOTS
    #define CYTHON_USE_TYPE_SLOTS 1
  #endif
  #ifndef CYTHON_USE_TYPE_SPECS
    #define CYTHON_USE_TYPE_SPECS 0
  #endif
  #ifndef CYTHON_USE_PYTYPE_LOOKUP
    #define CYTHON_USE_PYTYPE_LOOKUP 1
  #endif
  #if PY_MAJOR_VERSION < 3
    #undef CYTHON_USE_ASYNC_SLOTS
    #define CYTHON_USE_ASYNC_SLOTS 0
  #elif !defined(CYTHON_USE_ASYNC_SLOTS)
    #define CYTHON_USE_ASYNC_SLOTS 1
  #endif
  #ifndef CYTHON_USE_PYLONG_INTERNALS
    #define CYTHON_USE_PYLONG_INTERNALS 1
  #endif
  #ifndef CYTHON_USE_PYLIST_INTERNALS
    #define CYTHON_USE_PYLIST_INTERNALS 1
  #endif
  #ifndef CYTHON_USE_UNICODE_INTERNALS
    #define CYTHON_USE_UNICODE_INTERNALS 1
  #endif
  #if PY_VERSION_HEX < 0x030300F0 || PY_VERSION_HEX >= 0x030B00A2
    #undef CYTHON_USE_UNICODE_WRITER
    #define CYTHON_USE_UNICODE_WRITER 0
  #elif !defined(CYTHON_USE_UNICODE_WRITER)
    #define CYTHON_USE_UNICODE_WRITER 1
  #endif
  #ifndef CYTHON_AVOID_BORROWED_REFS
    #define CYTHON_AVOID_BORROWED_REFS 0
  #endif
  #ifndef CYTHON_ASSUME_SAFE_MACROS
    #define CYTHON_ASSUME_SAFE_MACROS 1
  #endif
  #ifndef CYTHON_UNPACK_METHODS
    #define CYTHON_UNPACK_METHODS 1
  #endif
  #ifndef CYTHON_FAST_THREAD_STATE
    #define CYTHON_FAST_THREAD_STATE 1
  #endif
  #ifndef CYTHON_FAST_GIL
    #define CYTHON_FAST_GIL (PY_MAJOR_VERSION < 3 || PY_VERSION_HEX >= 0x03060000 && PY_VERSION_HEX < 0x030C00A6)
  #endif
  #ifndef CYTHON_METH_FASTCALL
    #define CYTHON_METH_FASTCALL (PY_VERSION_HEX >= 0x030700A1)
  #endif
  #ifndef CYTHON_FAST_PYCALL
    #define CYTHON_FAST_PYCALL 1
  #endif
  #ifndef CYTHON_PEP487_INIT_SUBCLASS
    #define CYTHON_PEP487_INIT_SUBCLASS 1
  #endif
  #if PY_VERSION_HEX < 0x03050000
    #undef CYTHON_PEP489_MULTI_PHASE_INIT
    #define CYTHON_PEP489_MULTI_PHASE_INIT 0
  #elif !defined(CYTHON_PEP489_MULTI_PHASE_INIT)
    #define CYTHON_PEP489_MULTI_PHASE_INIT 1
  #endif
  #ifndef CYTHON_USE_MODULE_STATE
    #define CYTHON_USE_MODULE_STATE 0
  #endif
  #if PY_VERSION_HEX < 0x030400a1
    #undef CYTHON_USE_TP_FINALIZE
    #define CYTHON_USE_TP_FINALIZE 0
  #elif !defined(CYTHON_USE_TP_FINALIZE)
    #define CYTHON_USE_TP_FINALIZE 1
  #endif
  #if PY_VERSION_HEX < 0x030600B1
    #undef CYTHON_USE_DICT_VERSIONS
    #define CYTHON_USE_DICT_VERSIONS 0
  #elif !defined(CYTHON_USE_DICT_VERSIONS)
    #define CYTHON_USE_DICT_VERSIONS  (PY_VERSION_HEX < 0x030C00A5)
  #endif
  #if PY_VERSION_HEX < 0x030700A3
    #undef CYTHON_USE_EXC_INFO_STACK
    #define CYTHON_USE_EXC_INFO_STACK 0
  #elif !defined(CYTHON_USE_EXC_INFO_STACK)
    #define CYTHON_USE_EXC_INFO_STACK 1
  #endif
  #ifndef CYTHON_UPDATE_DESCRIPTOR_DOC
    #define CYTHON_UPDATE_DESCRIPTOR_DOC 1
  #endif
#endif
#if !defined(CYTHON_FAST_PYCCALL)
#define CYTHON_FAST_PYCCALL  (CYTHON_FAST_PYCALL && PY_VERSION_HEX >= 0x030600B1)
#endif
#if !defined(CYTHON_VECTORCALL)
#define CYTHON_VECTORCALL  (CYTHON_FAST_PYCCALL && PY_VERSION_HEX >= 0x030800B1)
#endif
#define CYTHON_BACKPORT_VECTORCALL (CYTHON_METH_FASTCALL && PY_VERSION_HEX < 0x030800B1)
#if CYTHON_USE_PYLONG_INTERNALS
  #if PY_MAJOR_VERSION < 3
    #include "longintrepr.h"
  #endif
  #undef SHIFT
  #undef BASE
  #undef MASK
  #ifdef SIZEOF_VOID_P
    enum { __pyx_check_sizeof_voidp = 1 / (int)(SIZEOF_VOID_P == sizeof(void*)) };
  #endif
#endif
#ifndef __has_attribute
  #define __has_attribute(x) 0
#endif
#ifndef __has_cpp_attribute
  #define __has_cpp_attribute(x) 0
#endif
#ifndef CYTHON_RESTRICT
  #if defined(__GNUC__)
    #define CYTHON_RESTRICT __restrict__
  #elif defined(_MSC_VER) && _MSC_VER >= 1400
    #define CYTHON_RESTRICT __restrict
  #elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define CYTHON_RESTRICT restrict
  #else
    #define CYTHON_RESTRICT
  #endif
#endif
#ifndef CYTHON_UNUSED
  #if defined(__cplusplus)
    /* for clang __has_cpp_attribute(maybe_unused) is true even before C++17
     * but leads to warnings with -pedantic, since it is a C++17 feature */
    #if ((defined(_MSVC_LANG) && _MSVC_LANG >= 201703L) || __cplusplus >= 201703L)
      #if __has_cpp_attribute(maybe_unused)
        #define CYTHON_UNUSED [[maybe_unused]]
      #endif
    #endif
  #endif
#endif
#ifndef CYTHON_UNUSED
# if defined(__GNUC__)
#   if !(defined(__cplusplus)) || (__GNUC__ > 3 || (__GNUC__ == 3 && __GNUC_MINOR__ >= 4))
#     define CYTHON_UNUSED __attribute__ ((__unused__))
#   else
#     define CYTHON_UNUSED
#   endif
# elif defined(__ICC) || (defined(__INTEL_COMPILER) && !defined(_MSC_VER))
#   define CYTHON_UNUSED __attribute__ ((__unused__))
# else
#   define CYTHON_UNUSED
# endif
#endif
#ifndef CYTHON_UNUSED_VAR
#  if defined(__cplusplus)
     template<class T> void CYTHON_UNUSED_VAR( const T& ) { }
#  else
#    define CYTHON_UNUSED_VAR(x) (void)(x)
#  endif
#endif
#ifndef CYTHON_MAYBE_UNUSED_VAR
  #define CYTHON_MAYBE_UNUSED_VAR(x) CYTHON_UNUSED_VAR(x)
#endif
#ifndef CYTHON_NCP_UNUSED
# if CYTHON_COMPILING_IN_CPYTHON
#  define CYTHON_NCP_UNUSED
# else
#  define CYTHON_NCP_UNUSED CYTHON_UNUSED
# endif
#endif
#ifndef CYTHON_USE_CPP_STD_MOVE
  #if defined(__cplusplus) && (\
    __cplusplus >= 201103L || (defined(_MSC_VER) && _MSC_VER >= 1600))
    #define CYTHON_USE_CPP_STD_MOVE 1
  #else
    #define CYTHON_USE_CPP_STD_MOVE 0
  #endif
#endif
#define __Pyx_void_to_None(void_result) ((void)(void_result), Py_INCREF(Py_None), Py_None)
#ifdef _MSC_VER
    #ifndef _MSC_STDINT_H_
        #if _MSC_VER < 1300
            typedef unsigned char     uint8_t;
            typedef unsigned short    uint16_t;
            typedef unsigned int      uint32_t;
        #else
            typedef unsigned __int8   uint8_t;
            typedef unsigned __int16  uint16_t;
            typedef unsigned __int32  uint32_t;
        #endif
    #endif
    #if _MSC_VER < 1300
        #ifdef _WIN64
            typedef unsigned long long  __pyx_uintptr_t;
        #else
            typedef unsigned int        __pyx_uintptr_t;
        #endif
    #else
        #ifdef _WIN64
            typedef unsigned __int64    __pyx_uintptr_t;
        #else
            typedef unsigned __int32    __pyx_uintptr_t;
        #endif
    #endif
#else
    #include <stdint.h>
    typedef uintptr_t  __pyx_uintptr_t;
#endif
#ifndef CYTHON_FALLTHROUGH
  #if defined(__cplusplus)
    /* for clang __has_cpp_attribute(fallthrough) is true even before C++17
     * but leads to warnings with -pedantic, since it is a C++17 feature */
    #if ((defined(_MSVC_LANG) && _MSVC_LANG >= 201703L) || __cplusplus >= 201703L)
      #if __has_cpp_attribute(fallthrough)
        #define CYTHON_FALLTHROUGH [[fallthrough]]
      #endif
    #endif
    #ifndef CYTHON_FALLTHROUGH
      #if __has_cpp_attribute(clang::fallthrough)
        #define CYTHON_FALLTHROUGH [[clang::fallthrough]]
      #elif __has_cpp_attribute(gnu::fallthrough)
        #define CYTHON_FALLTHROUGH [[gnu::fallthrough]]
      #endif
    #endif
  #endif
  #ifndef CYTHON_FALLTHROUGH
    #if __has_attribute(fallthrough)
      #define CYTHON_FALLTHROUGH __attribute__((fallthrough))
    #else
      #define CYTHON_FALLTHROUGH
    #endif
  #endif
  #if defined(__clang__) && defined(__apple_build_version__)
    #if __apple_build_version__ < 7000000
      #undef  CYTHON_FALLTHROUGH
      #define CYTHON_FALLTHROUGH
    #endif
  #endif
#endif
#ifdef __cplusplus
  template <typename T>
  struct __PYX_IS_UNSIGNED_IMPL {static const bool value = T(0) < T(-1);};
  #define __PYX_IS_UNSIGNED(type) (__PYX_IS_UNSIGNED_IMPL<type>::value)
#else
  #define __PYX_IS_UNSIGNED(type) (((type)-1) > 0)
#endif
#if CYTHON_COMPILING_IN_PYPY == 1
  #define __PYX_NEED_TP_PRINT_SLOT  (PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x030A0000)
#else
  #define __PYX_NEED_TP_PRINT_SLOT  (PY_VERSION_HEX >= 0x030800b4 && PY_VERSION_HEX < 0x03090000)
#endif
#define __PYX_REINTERPRET_FUNCION(func_pointer, other_pointer) ((func_pointer)(void(*)(void))(other_pointer))

#ifndef CYTHON_INLINE
  #if defined(__clang__)
    #define CYTHON_INLINE __inline__ __attribute__ ((__unused__))
  #elif defined(__GNUC__)
    #define CYTHON_INLINE __inline__
  #elif defined(_MSC_VER)
    #define CYTHON_INLINE __inline
  #elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define CYTHON_INLINE inline
  #else
    #define CYTHON_INLINE
  #endif
#endif

#define __PYX_BUILD_PY_SSIZE_T "n"
#define CYTHON_FORMAT_SSIZE_T "z"
#if PY_MAJOR_VERSION < 3
  #define __Pyx_BUILTIN_MODULE_NAME "__builtin__"
  #define __Pyx_DefaultClassType PyClass_Type
  #define __Pyx_PyCode_New(a, p, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)\
          PyCode_New(a+k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)
#else
  #define __Pyx_BUILTIN_MODULE_NAME "builtins"
  #define __Pyx_DefaultClassType PyType_Type
#if CYTHON_COMPILING_IN_LIMITED_API
    static CYTHON_INLINE PyObject* __Pyx_PyCode_New(int a, int p, int k, int l, int s, int f,
                                                    PyObject *code, PyObject *c, PyObject* n, PyObject *v,
                                                    PyObject *fv, PyObject *cell, PyObject* fn,
                                                    PyObject *name, int fline, PyObject *lnos) {
        PyObject *exception_table = NULL;
        PyObject *types_module=NULL, *code_type=NULL, *result=NULL;
        PyObject *version_info; // borrowed
        PyObject *py_minor_version = NULL;
        long minor_version = 0;
        PyObject *type, *value, *traceback;
        PyErr_Fetch(&type, &value, &traceback);
        #if __PYX_LIMITED_VERSION_HEX >= 0x030B0000
        minor_version = 11; // we don't yet need to distinguish between versions > 11
        #else
        if (!(version_info = PySys_GetObject("version_info"))) goto end;
        if (!(py_minor_version = PySequence_GetItem(version_info, 1))) goto end;
        minor_version = PyLong_AsLong(py_minor_version);
        if (minor_version == -1 && PyErr_Occurred()) goto end;
        #endif
        if (!(types_module = PyImport_ImportModule("types"))) goto end;
        if (!(code_type = PyObject_GetAttrString(types_module, "CodeType"))) goto end;
        if (minor_version <= 7) {
            (void)p;
            result = PyObject_CallFunction(code_type, "iiiiiOOOOOOiOO", a, k, l, s, f, code,
                          c, n, v, fn, name, fline, lnos, fv, cell);
        } else if (minor_version <= 10) {
            result = PyObject_CallFunction(code_type, "iiiiiiOOOOOOiOO", a,p, k, l, s, f, code,
                          c, n, v, fn, name, fline, lnos, fv, cell);
        } else {
            if (!(exception_table = PyBytes_FromStringAndSize(NULL, 0))) goto end;
            result = PyObject_CallFunction(code_type, "iiiiiiOOOOOOOiOO", a,p, k, l, s, f, code,
                          c, n, v, fn, name, name, fline, lnos, exception_table, fv, cell);
        }
    end:
        Py_XDECREF(code_type);
        Py_XDECREF(exception_table);
        Py_XDECREF(types_module);
        Py_XDECREF(py_minor_version);
        if (type) {
            PyErr_Restore(type, value, traceback);
        }
        return result;
    }
    #ifndef CO_OPTIMIZED
    #define CO_OPTIMIZED 0x0001
    #endif
    #ifndef CO_NEWLOCALS
    #define CO_NEWLOCALS 0x0002
    #endif
    #ifndef CO_VARARGS
    #define CO_VARARGS 0x0004
    #endif
    #ifndef CO_VARKEYWORDS
    #define CO_VARKEYWORDS 0x0008
    #endif
    #ifndef CO_ASYNC_GENERATOR
    #define CO_ASYNC_GENERATOR 0x0200
    #endif
    #ifndef CO_GENERATOR
    #define CO_GENERATOR 0x0020
    #endif
    #ifndef CO_COROUTINE
    #define CO_COROUTINE 0x0080
    #endif
#elif PY_VERSION_HEX >= 0x030B0000
  static CYTHON_INLINE PyCodeObject* __Pyx_PyCode_New(int a, int p, int k, int l, int s, int f,
                                                    PyObject *code, PyObject *c, PyObject* n, PyObject *v,
                                                    PyObject *fv, PyObject *cell, PyObject* fn,
                                                    PyObject *name, int fline, PyObject *lnos) {
    PyCodeObject *result;
    PyObject *empty_bytes = PyBytes_FromStringAndSize("", 0);  // we don't have access to __pyx_empty_bytes here
    if (!empty_bytes) return NULL;
    result =
      #if PY_VERSION_HEX >= 0x030C0000
        PyUnstable_Code_NewWithPosOnlyArgs
      #else
        PyCode_NewWithPosOnlyArgs
      #endif
        (a, p, k, l, s, f, code, c, n, v, fv, cell, fn, name, name, fline, lnos, empty_bytes);
    Py_DECREF(empty_bytes);
    return result;
  }
#elif PY_VERSION_HEX >= 0x030800B2 && !CYTHON_COMPILING_IN_PYPY
  #define __Pyx_PyCode_New(a, p, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)\
          PyCode_NewWithPosOnlyArgs(a, p, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)
#else
  #define __Pyx_PyCode_New(a, p, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)\
          PyCode_New(a, k, l, s, f, code, c, n, v, fv, cell, fn, name, fline, lnos)
#endif
#endif
#if PY_VERSION_HEX >= 0x030900A4 || defined(Py_IS_TYPE)
  #define __Pyx_IS_TYPE(ob, type) Py_IS_TYPE(ob, type)
#else
  #define __Pyx_IS_TYPE(ob, type) (((const PyObject*)ob)->ob_type == (type))
#endif
#if PY_VERSION_HEX >= 0x030A00B1 || defined(Py_Is)
  #define __Pyx_Py_Is(x, y)  Py_Is(x, y)
#else
  #define __Pyx_Py_Is(x, y) ((x) == (y))
#endif
#if PY_VERSION_HEX >= 0x030A00B1 || defined(Py_IsNone)
  #define __Pyx_Py_IsNone(ob) Py_IsNone(ob)
#else
  #define __Pyx_Py_IsNone(ob) __Pyx_Py_Is((ob), Py_None)
#endif
#if PY_VERSION_HEX >= 0x030A00B1 || defined(Py_IsTrue)
  #define __Pyx_Py_IsTrue(ob) Py_IsTrue(ob)
#else
  #define __Pyx_Py_IsTrue(ob) __Pyx_Py_Is((ob), Py_True)
#endif
#if PY_VERSION_HEX >= 0x030A00B1 || defined(Py_IsFalse)
  #define __Pyx_Py_IsFalse(ob) Py_IsFalse(ob)
#else
  #define __Pyx_Py_IsFalse(ob) __Pyx_Py_Is((ob), Py_False)
#endif
#define __Pyx_NoneAsNull(obj)  (__Pyx_Py_IsNone(obj) ? NULL : (obj))
#if PY_VERSION_HEX >= 0x030900F0 && !CYTHON_COMPILING_IN_PYPY
  #define __Pyx_PyObject_GC_IsFinalized(o) PyObject_GC_IsFinalized(o)
#else
  #define __Pyx_PyObject_GC_IsFinalized(o) _PyGC_FINALIZED(o)
#endif
#ifndef CO_COROUTINE
  #define CO_COROUTINE 0x80
#endif
#ifndef CO_ASYNC_GENERATOR
  #define CO_ASYNC_GENERATOR 0x200
#endif
#ifndef Py_TPFLAGS_CHECKTYPES
  #define Py_TPFLAGS_CHECKTYPES 0
#endif
#ifndef Py_TPFLAGS_HAVE_INDEX
  #define Py_TPFLAGS_HAVE_INDEX 0
#endif
#ifndef Py_TPFLAGS_HAVE_NEWBUFFER
  #define Py_TPFLAGS_HAVE_NEWBUFFER 0
#endif
#ifndef Py_TPFLAGS_HAVE_FINALIZE
  #define Py_TPFLAGS_HAVE_FINALIZE 0
#endif
#ifndef Py_TPFLAGS_SEQUENCE
  #define Py_TPFLAGS_SEQUENCE 0
#endif
#ifndef Py_TPFLAGS_MAPPING
  #define Py_TPFLAGS_MAPPING 0
#endif
#ifndef METH_STACKLESS
  #define METH_STACKLESS 0
#endif
#if PY_VERSION_HEX <= 0x030700A3 || !defined(METH_FASTCALL)
  #ifndef METH_FASTCALL
     #define METH_FASTCALL 0x80
  #endif
  typedef PyObject *(*__Pyx_PyCFunctionFast) (PyObject *self, PyObject *const *args, Py_ssize_t nargs);
  typedef PyObject *(*__Pyx_PyCFunctionFastWithKeywords) (PyObject *self, PyObject *const *args,
                                                          Py_ssize_t nargs, PyObject *kwnames);
#else
  #define __Pyx_PyCFunctionFast _PyCFunctionFast
  #define __Pyx_PyCFunctionFastWithKeywords _PyCFunctionFastWithKeywords
#endif
#if CYTHON_METH_FASTCALL
  #define __Pyx_METH_FASTCALL METH_FASTCALL
  #define __Pyx_PyCFunction_FastCall __Pyx_PyCFunctionFast
  #define __Pyx_PyCFunction_FastCallWithKeywords __Pyx_PyCFunctionFastWithKeywords
#else
  #define __Pyx_METH_FASTCALL METH_VARARGS
  #define __Pyx_PyCFunction_FastCall PyCFunction
  #define __Pyx_PyCFunction_FastCallWithKeywords PyCFunctionWithKeywords
#endif
#if CYTHON_VECTORCALL
  #define __pyx_vectorcallfunc vectorcallfunc
  #define __Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET  PY_VECTORCALL_ARGUMENTS_OFFSET
  #define __Pyx_PyVectorcall_NARGS(n)  PyVectorcall_NARGS((size_t)(n))
#elif CYTHON_BACKPORT_VECTORCALL
  typedef PyObject *(*__pyx_vectorcallfunc)(PyObject *callable, PyObject *const *args,
                                            size_t nargsf, PyObject *kwnames);
  #define __Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET  ((size_t)1 << (8 * sizeof(size_t) - 1))
  #define __Pyx_PyVectorcall_NARGS(n)  ((Py_ssize_t)(((size_t)(n)) & ~__Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET))
#else
  #define __Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET  0
  #define __Pyx_PyVectorcall_NARGS(n)  ((Py_ssize_t)(n))
#endif
#if __PYX_LIMITED_VERSION_HEX < 0x030900B1
  #define __Pyx_PyType_FromModuleAndSpec(m, s, b)  ((void)m, PyType_FromSpecWithBases(s, b))
  typedef PyObject *(*__Pyx_PyCMethod)(PyObject *, PyTypeObject *, PyObject *const *, size_t, PyObject *);
#else
  #define __Pyx_PyType_FromModuleAndSpec(m, s, b)  PyType_FromModuleAndSpec(m, s, b)
  #define __Pyx_PyCMethod  PyCMethod
#endif
#ifndef METH_METHOD
  #define METH_METHOD 0x200
#endif
#if CYTHON_COMPILING_IN_PYPY && !defined(PyObject_Malloc)
  #define PyObject_Malloc(s)   PyMem_Malloc(s)
  #define PyObject_Free(p)     PyMem_Free(p)
  #define PyObject_Realloc(p)  PyMem_Realloc(p)
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
  #define __Pyx_PyCode_HasFreeVars(co)  (PyCode_GetNumFree(co) > 0)
  #define __Pyx_PyFrame_SetLineNumber(frame, lineno)
#else
  #define __Pyx_PyCode_HasFreeVars(co)  (PyCode_GetNumFree(co) > 0)
  #define __Pyx_PyFrame_SetLineNumber(frame, lineno)  (frame)->f_lineno = (lineno)
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
  #define __Pyx_PyThreadState_Current PyThreadState_Get()
#elif !CYTHON_FAST_THREAD_STATE
  #define __Pyx_PyThreadState_Current PyThreadState_GET()
#elif PY_VERSION_HEX >= 0x03060000
  #define __Pyx_PyThreadState_Current _PyThreadState_UncheckedGet()
#elif PY_VERSION_HEX >= 0x03000000
  #define __Pyx_PyThreadState_Current PyThreadState_GET()
#else
  #define __Pyx_PyThreadState_Current _PyThreadState_Current
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
static CYTHON_INLINE void *__Pyx_PyModule_GetState(PyObject *op)
{
    void *result;
    result = PyModule_GetState(op);
    if (!result)
        Py_FatalError("Couldn't find the module state");
    return result;
}
#endif
#define __Pyx_PyObject_GetSlot(obj, name, func_ctype)  __Pyx_PyType_GetSlot(Py_TYPE(obj), name, func_ctype)
#if CYTHON_COMPILING_IN_LIMITED_API
  #define __Pyx_PyType_GetSlot(type, name, func_ctype)  ((func_ctype) PyType_GetSlot((type), Py_##name))
#else
  #define __Pyx_PyType_GetSlot(type, name, func_ctype)  ((type)->name)
#endif
#if PY_VERSION_HEX < 0x030700A2 && !defined(PyThread_tss_create) && !defined(Py_tss_NEEDS_INIT)
#include "pythread.h"
#define Py_tss_NEEDS_INIT 0
typedef int Py_tss_t;
static CYTHON_INLINE int PyThread_tss_create(Py_tss_t *key) {
  *key = PyThread_create_key();
  return 0;
}
static CYTHON_INLINE Py_tss_t * PyThread_tss_alloc(void) {
  Py_tss_t *key = (Py_tss_t *)PyObject_Malloc(sizeof(Py_tss_t));
  *key = Py_tss_NEEDS_INIT;
  return key;
}
static CYTHON_INLINE void PyThread_tss_free(Py_tss_t *key) {
  PyObject_Free(key);
}
static CYTHON_INLINE int PyThread_tss_is_created(Py_tss_t *key) {
  return *key != Py_tss_NEEDS_INIT;
}
static CYTHON_INLINE void PyThread_tss_delete(Py_tss_t *key) {
  PyThread_delete_key(*key);
  *key = Py_tss_NEEDS_INIT;
}
static CYTHON_INLINE int PyThread_tss_set(Py_tss_t *key, void *value) {
  return PyThread_set_key_value(*key, value);
}
static CYTHON_INLINE void * PyThread_tss_get(Py_tss_t *key) {
  return PyThread_get_key_value(*key);
}
#endif
#if PY_MAJOR_VERSION < 3
    #if CYTHON_COMPILING_IN_PYPY
        #if PYPY_VERSION_NUM < 0x07030600
            #if defined(__cplusplus) && __cplusplus >= 201402L
                [[deprecated("`with nogil:` inside a nogil function will not release the GIL in PyPy2 < 7.3.6")]]
            #elif defined(__GNUC__) || defined(__clang__)
                __attribute__ ((__deprecated__("`with nogil:` inside a nogil function will not release the GIL in PyPy2 < 7.3.6")))
            #elif defined(_MSC_VER)
                __declspec(deprecated("`with nogil:` inside a nogil function will not release the GIL in PyPy2 < 7.3.6"))
            #endif
            static CYTHON_INLINE int PyGILState_Check(void) {
                return 0;
            }
        #else  // PYPY_VERSION_NUM < 0x07030600
        #endif  // PYPY_VERSION_NUM < 0x07030600
    #else
        static CYTHON_INLINE int PyGILState_Check(void) {
            PyThreadState * tstate = _PyThreadState_Current;
            return tstate && (tstate == PyGILState_GetThisThreadState());
        }
    #endif
#endif
#if CYTHON_COMPILING_IN_CPYTHON || defined(_PyDict_NewPresized)
#define __Pyx_PyDict_NewPresized(n)  ((n <= 8) ? PyDict_New() : _PyDict_NewPresized(n))
#else
#define __Pyx_PyDict_NewPresized(n)  PyDict_New()
#endif
#if PY_MAJOR_VERSION >= 3 || CYTHON_FUTURE_DIVISION
  #define __Pyx_PyNumber_Divide(x,y)         PyNumber_TrueDivide(x,y)
  #define __Pyx_PyNumber_InPlaceDivide(x,y)  PyNumber_InPlaceTrueDivide(x,y)
#else
  #define __Pyx_PyNumber_Divide(x,y)         PyNumber_Divide(x,y)
  #define __Pyx_PyNumber_InPlaceDivide(x,y)  PyNumber_InPlaceDivide(x,y)
#endif
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX > 0x030600B4 && CYTHON_USE_UNICODE_INTERNALS
#define __Pyx_PyDict_GetItemStrWithError(dict, name)  _PyDict_GetItem_KnownHash(dict, name, ((PyASCIIObject *) name)->hash)
static CYTHON_INLINE PyObject * __Pyx_PyDict_GetItemStr(PyObject *dict, PyObject *name) {
    PyObject *res = __Pyx_PyDict_GetItemStrWithError(dict, name);
    if (res == NULL) PyErr_Clear();
    return res;
}
#elif PY_MAJOR_VERSION >= 3 && (!CYTHON_COMPILING_IN_PYPY || PYPY_VERSION_NUM >= 0x07020000)
#define __Pyx_PyDict_GetItemStrWithError  PyDict_GetItemWithError
#define __Pyx_PyDict_GetItemStr           PyDict_GetItem
#else
static CYTHON_INLINE PyObject * __Pyx_PyDict_GetItemStrWithError(PyObject *dict, PyObject *name) {
#if CYTHON_COMPILING_IN_PYPY
    return PyDict_GetItem(dict, name);
#else
    PyDictEntry *ep;
    PyDictObject *mp = (PyDictObject*) dict;
    long hash = ((PyStringObject *) name)->ob_shash;
    assert(hash != -1);
    ep = (mp->ma_lookup)(mp, name, hash);
    if (ep == NULL) {
        return NULL;
    }
    return ep->me_value;
#endif
}
#define __Pyx_PyDict_GetItemStr           PyDict_GetItem
#endif
#if CYTHON_USE_TYPE_SLOTS
  #define __Pyx_PyType_GetFlags(tp)   (((PyTypeObject *)tp)->tp_flags)
  #define __Pyx_PyType_HasFeature(type, feature)  ((__Pyx_PyType_GetFlags(type) & (feature)) != 0)
  #define __Pyx_PyObject_GetIterNextFunc(obj)  (Py_TYPE(obj)->tp_iternext)
#else
  #define __Pyx_PyType_GetFlags(tp)   (PyType_GetFlags((PyTypeObject *)tp))
  #define __Pyx_PyType_HasFeature(type, feature)  PyType_HasFeature(type, feature)
  #define __Pyx_PyObject_GetIterNextFunc(obj)  PyIter_Next
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
  #define __Pyx_SetItemOnTypeDict(tp, k, v) PyObject_GenericSetAttr((PyObject*)tp, k, v)
#else
  #define __Pyx_SetItemOnTypeDict(tp, k, v) PyDict_SetItem(tp->tp_dict, k, v)
#endif
#if CYTHON_USE_TYPE_SPECS && PY_VERSION_HEX >= 0x03080000
#define __Pyx_PyHeapTypeObject_GC_Del(obj)  {\
    PyTypeObject *type = Py_TYPE(obj);\
    assert(__Pyx_PyType_HasFeature(type, Py_TPFLAGS_HEAPTYPE));\
    PyObject_GC_Del(obj);\
    Py_DECREF(type);\
}
#else
#define __Pyx_PyHeapTypeObject_GC_Del(obj)  PyObject_GC_Del(obj)
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
  #define CYTHON_PEP393_ENABLED 1
  #define __Pyx_PyUnicode_READY(op)       (0)
  #define __Pyx_PyUnicode_GET_LENGTH(u)   PyUnicode_GetLength(u)
  #define __Pyx_PyUnicode_READ_CHAR(u, i) PyUnicode_ReadChar(u, i)
  #define __Pyx_PyUnicode_MAX_CHAR_VALUE(u)   ((void)u, 1114111U)
  #define __Pyx_PyUnicode_KIND(u)         ((void)u, (0))
  #define __Pyx_PyUnicode_DATA(u)         ((void*)u)
  #define __Pyx_PyUnicode_READ(k, d, i)   ((void)k, PyUnicode_ReadChar((PyObject*)(d), i))
  #define __Pyx_PyUnicode_IS_TRUE(u)      (0 != PyUnicode_GetLength(u))
#elif PY_VERSION_HEX > 0x03030000 && defined(PyUnicode_KIND)
  #define CYTHON_PEP393_ENABLED 1
  #if PY_VERSION_HEX >= 0x030C0000
    #define __Pyx_PyUnicode_READY(op)       (0)
  #else
    #define __Pyx_PyUnicode_READY(op)       (likely(PyUnicode_IS_READY(op)) ?\
                                                0 : _PyUnicode_Ready((PyObject *)(op)))
  #endif
  #define __Pyx_PyUnicode_GET_LENGTH(u)   PyUnicode_GET_LENGTH(u)
  #define __Pyx_PyUnicode_READ_CHAR(u, i) PyUnicode_READ_CHAR(u, i)
  #define __Pyx_PyUnicode_MAX_CHAR_VALUE(u)   PyUnicode_MAX_CHAR_VALUE(u)
  #define __Pyx_PyUnicode_KIND(u)         ((int)PyUnicode_KIND(u))
  #define __Pyx_PyUnicode_DATA(u)         PyUnicode_DATA(u)
  #define __Pyx_PyUnicode_READ(k, d, i)   PyUnicode_READ(k, d, i)
  #define __Pyx_PyUnicode_WRITE(k, d, i, ch)  PyUnicode_WRITE(k, d, i, (Py_UCS4) ch)
  #if PY_VERSION_HEX >= 0x030C0000
    #define __Pyx_PyUnicode_IS_TRUE(u)      (0 != PyUnicode_GET_LENGTH(u))
  #else
    #if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x03090000
    #define __Pyx_PyUnicode_IS_TRUE(u)      (0 != (likely(PyUnicode_IS_READY(u)) ? PyUnicode_GET_LENGTH(u) : ((PyCompactUnicodeObject *)(u))->wstr_length))
    #else
    #define __Pyx_PyUnicode_IS_TRUE(u)      (0 != (likely(PyUnicode_IS_READY(u)) ? PyUnicode_GET_LENGTH(u) : PyUnicode_GET_SIZE(u)))
    #endif
  #endif
#else
  #define CYTHON_PEP393_ENABLED 0
  #define PyUnicode_1BYTE_KIND  1
  #define PyUnicode_2BYTE_KIND  2
  #define PyUnicode_4BYTE_KIND  4
  #define __Pyx_PyUnicode_READY(op)       (0)
  #define __Pyx_PyUnicode_GET_LENGTH(u)   PyUnicode_GET_SIZE(u)
  #define __Pyx_PyUnicode_READ_CHAR(u, i) ((Py_UCS4)(PyUnicode_AS_UNICODE(u)[i]))
  #define __Pyx_PyUnicode_MAX_CHAR_VALUE(u)   ((sizeof(Py_UNICODE) == 2) ? 65535U : 1114111U)
  #define __Pyx_PyUnicode_KIND(u)         ((int)sizeof(Py_UNICODE))
  #define __Pyx_PyUnicode_DATA(u)         ((void*)PyUnicode_AS_UNICODE(u))
  #define __Pyx_PyUnicode_READ(k, d, i)   ((void)(k), (Py_UCS4)(((Py_UNICODE*)d)[i]))
  #define __Pyx_PyUnicode_WRITE(k, d, i, ch)  (((void)(k)), ((Py_UNICODE*)d)[i] = (Py_UNICODE) ch)
  #define __Pyx_PyUnicode_IS_TRUE(u)      (0 != PyUnicode_GET_SIZE(u))
#endif
#if CYTHON_COMPILING_IN_PYPY
  #define __Pyx_PyUnicode_Concat(a, b)      PyNumber_Add(a, b)
  #define __Pyx_PyUnicode_ConcatSafe(a, b)  PyNumber_Add(a, b)
#else
  #define __Pyx_PyUnicode_Concat(a, b)      PyUnicode_Concat(a, b)
  #define __Pyx_PyUnicode_ConcatSafe(a, b)  ((unlikely((a) == Py_None) || unlikely((b) == Py_None)) ?\
      PyNumber_Add(a, b) : __Pyx_PyUnicode_Concat(a, b))
#endif
#if CYTHON_COMPILING_IN_PYPY
  #if !defined(PyUnicode_DecodeUnicodeEscape)
    #define PyUnicode_DecodeUnicodeEscape(s, size, errors)  PyUnicode_Decode(s, size, "unicode_escape", errors)
  #endif
  #if !defined(PyUnicode_Contains) || (PY_MAJOR_VERSION == 2 && PYPY_VERSION_NUM < 0x07030500)
    #undef PyUnicode_Contains
    #define PyUnicode_Contains(u, s)  PySequence_Contains(u, s)
  #endif
  #if !defined(PyByteArray_Check)
    #define PyByteArray_Check(obj)  PyObject_TypeCheck(obj, &PyByteArray_Type)
  #endif
  #if !defined(PyObject_Format)
    #define PyObject_Format(obj, fmt)  PyObject_CallMethod(obj, "__format__", "O", fmt)
  #endif
#endif
#define __Pyx_PyString_FormatSafe(a, b)   ((unlikely((a) == Py_None || (PyString_Check(b) && !PyString_CheckExact(b)))) ? PyNumber_Remainder(a, b) : __Pyx_PyString_Format(a, b))
#define __Pyx_PyUnicode_FormatSafe(a, b)  ((unlikely((a) == Py_None || (PyUnicode_Check(b) && !PyUnicode_CheckExact(b)))) ? PyNumber_Remainder(a, b) : PyUnicode_Format(a, b))
#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyString_Format(a, b)  PyUnicode_Format(a, b)
#else
  #define __Pyx_PyString_Format(a, b)  PyString_Format(a, b)
#endif
#if PY_MAJOR_VERSION < 3 && !defined(PyObject_ASCII)
  #define PyObject_ASCII(o)            PyObject_Repr(o)
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBaseString_Type            PyUnicode_Type
  #define PyStringObject               PyUnicodeObject
  #define PyString_Type                PyUnicode_Type
  #define PyString_Check               PyUnicode_Check
  #define PyString_CheckExact          PyUnicode_CheckExact
#ifndef PyObject_Unicode
  #define PyObject_Unicode             PyObject_Str
#endif
#endif
#if PY_MAJOR_VERSION >= 3
  #define __Pyx_PyBaseString_Check(obj) PyUnicode_Check(obj)
  #define __Pyx_PyBaseString_CheckExact(obj) PyUnicode_CheckExact(obj)
#else
  #define __Pyx_PyBaseString_Check(obj) (PyString_Check(obj) || PyUnicode_Check(obj))
  #define __Pyx_PyBaseString_CheckExact(obj) (PyString_CheckExact(obj) || PyUnicode_CheckExact(obj))
#endif
#if CYTHON_COMPILING_IN_CPYTHON
  #define __Pyx_PySequence_ListKeepNew(obj)\
    (likely(PyList_CheckExact(obj) && Py_REFCNT(obj) == 1) ? __Pyx_NewRef(obj) : PySequence_List(obj))
#else
  #define __Pyx_PySequence_ListKeepNew(obj)  PySequence_List(obj)
#endif
#ifndef PySet_CheckExact
  #define PySet_CheckExact(obj)        __Pyx_IS_TYPE(obj, &PySet_Type)
#endif
#if PY_VERSION_HEX >= 0x030900A4
  #define __Pyx_SET_REFCNT(obj, refcnt) Py_SET_REFCNT(obj, refcnt)
  #define __Pyx_SET_SIZE(obj, size) Py_SET_SIZE(obj, size)
#else
  #define __Pyx_SET_REFCNT(obj, refcnt) Py_REFCNT(obj) = (refcnt)
  #define __Pyx_SET_SIZE(obj, size) Py_SIZE(obj) = (size)
#endif
#if CYTHON_ASSUME_SAFE_MACROS
  #define __Pyx_PySequence_ITEM(o, i) PySequence_ITEM(o, i)
  #define __Pyx_PySequence_SIZE(seq)  Py_SIZE(seq)
  #define __Pyx_PyTuple_SET_ITEM(o, i, v) (PyTuple_SET_ITEM(o, i, v), (0))
  #define __Pyx_PyList_SET_ITEM(o, i, v) (PyList_SET_ITEM(o, i, v), (0))
  #define __Pyx_PyTuple_GET_SIZE(o) PyTuple_GET_SIZE(o)
  #define __Pyx_PyList_GET_SIZE(o) PyList_GET_SIZE(o)
  #define __Pyx_PySet_GET_SIZE(o) PySet_GET_SIZE(o)
  #define __Pyx_PyBytes_GET_SIZE(o) PyBytes_GET_SIZE(o)
  #define __Pyx_PyByteArray_GET_SIZE(o) PyByteArray_GET_SIZE(o)
#else
  #define __Pyx_PySequence_ITEM(o, i) PySequence_GetItem(o, i)
  #define __Pyx_PySequence_SIZE(seq)  PySequence_Size(seq)
  #define __Pyx_PyTuple_SET_ITEM(o, i, v) PyTuple_SetItem(o, i, v)
  #define __Pyx_PyList_SET_ITEM(o, i, v) PyList_SetItem(o, i, v)
  #define __Pyx_PyTuple_GET_SIZE(o) PyTuple_Size(o)
  #define __Pyx_PyList_GET_SIZE(o) PyList_Size(o)
  #define __Pyx_PySet_GET_SIZE(o) PySet_Size(o)
  #define __Pyx_PyBytes_GET_SIZE(o) PyBytes_Size(o)
  #define __Pyx_PyByteArray_GET_SIZE(o) PyByteArray_Size(o)
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyIntObject                  PyLongObject
  #define PyInt_Type                   PyLong_Type
  #define PyInt_Check(op)              PyLong_Check(op)
  #define PyInt_CheckExact(op)         PyLong_CheckExact(op)
  #define __Pyx_Py3Int_Check(op)       PyLong_Check(op)
  #define __Pyx_Py3Int_CheckExact(op)  PyLong_CheckExact(op)
  #define PyInt_FromString             PyLong_FromString
  #define PyInt_FromUnicode            PyLong_FromUnicode
  #define PyInt_FromLong               PyLong_FromLong
  #define PyInt_FromSize_t             PyLong_FromSize_t
  #define PyInt_FromSsize_t            PyLong_FromSsize_t
  #define PyInt_AsLong                 PyLong_AsLong
  #define PyInt_AS_LONG                PyLong_AS_LONG
  #define PyInt_AsSsize_t              PyLong_AsSsize_t
  #define PyInt_AsUnsignedLongMask     PyLong_AsUnsignedLongMask
  #define PyInt_AsUnsignedLongLongMask PyLong_AsUnsignedLongLongMask
  #define PyNumber_Int                 PyNumber_Long
#else
  #define __Pyx_Py3Int_Check(op)       (PyLong_Check(op) || PyInt_Check(op))
  #define __Pyx_Py3Int_CheckExact(op)  (PyLong_CheckExact(op) || PyInt_CheckExact(op))
#endif
#if PY_MAJOR_VERSION >= 3
  #define PyBoolObject                 PyLongObject
#endif
#if PY_MAJOR_VERSION >= 3 && CYTHON_COMPILING_IN_PYPY
  #ifndef PyUnicode_InternFromString
    #define PyUnicode_InternFromString(s) PyUnicode_FromString(s)
  #endif
#endif
#if PY_VERSION_HEX < 0x030200A4
  typedef long Py_hash_t;
  #define __Pyx_PyInt_FromHash_t PyInt_FromLong
  #define __Pyx_PyInt_AsHash_t   __Pyx_PyIndex_AsHash_t
#else
  #define __Pyx_PyInt_FromHash_t PyInt_FromSsize_t
  #define __Pyx_PyInt_AsHash_t   __Pyx_PyIndex_AsSsize_t
#endif
#if CYTHON_USE_ASYNC_SLOTS
  #if PY_VERSION_HEX >= 0x030500B1
    #define __Pyx_PyAsyncMethodsStruct PyAsyncMethods
    #define __Pyx_PyType_AsAsync(obj) (Py_TYPE(obj)->tp_as_async)
  #else
    #define __Pyx_PyType_AsAsync(obj) ((__Pyx_PyAsyncMethodsStruct*) (Py_TYPE(obj)->tp_reserved))
  #endif
#else
  #define __Pyx_PyType_AsAsync(obj) NULL
#endif
#ifndef __Pyx_PyAsyncMethodsStruct
    typedef struct {
        unaryfunc am_await;
        unaryfunc am_aiter;
        unaryfunc am_anext;
    } __Pyx_PyAsyncMethodsStruct;
#endif

#if defined(_WIN32) || defined(WIN32) || defined(MS_WINDOWS)
  #if !defined(_USE_MATH_DEFINES)
    #define _USE_MATH_DEFINES
  #endif
#endif
#include <math.h>
#ifdef NAN
#define __PYX_NAN() ((float) NAN)
#else
static CYTHON_INLINE float __PYX_NAN() {
  float value;
  memset(&value, 0xFF, sizeof(value));
  return value;
}
#endif
#if defined(__CYGWIN__) && defined(_LDBL_EQ_DBL)
#define __Pyx_truncl trunc
#else
#define __Pyx_truncl truncl
#endif

#define __PYX_MARK_ERR_POS(f_index, lineno) \
    { __pyx_filename = __pyx_f[f_index]; (void)__pyx_filename; __pyx_lineno = lineno; (void)__pyx_lineno; __pyx_clineno = __LINE__; (void)__pyx_clineno; }
#define __PYX_ERR(f_index, lineno, Ln_error) \
    { __PYX_MARK_ERR_POS(f_index, lineno) goto Ln_error; }

#ifdef CYTHON_EXTERN_C
    #undef __PYX_EXTERN_C
    #define __PYX_EXTERN_C CYTHON_EXTERN_C
#elif defined(__PYX_EXTERN_C)
    #ifdef _MSC_VER
    #pragma message ("Please do not define the '__PYX_EXTERN_C' macro externally. Use 'CYTHON_EXTERN_C' instead.")
    #else
    #warning Please do not define the '__PYX_EXTERN_C' macro externally. Use 'CYTHON_EXTERN_C' instead.
    #endif
#else
  #ifdef __cplusplus
    #define __PYX_EXTERN_C extern "C"
  #else
    #define __PYX_EXTERN_C extern
  #endif
#endif

#define __PYX_HAVE__pysam__libcutils
#define __PYX_HAVE_API__pysam__libcutils
/* Early includes */
#include <string.h>
#include <stdio.h>
#include "pythread.h"

    #if CYTHON_COMPILING_IN_PYPY
    #ifdef _MSC_VER
    #pragma message ("This module uses CPython specific internals of 'array.array', which are not available in PyPy.")
    #else
    #warning This module uses CPython specific internals of 'array.array', which are not available in PyPy.
    #endif
    #endif
    
#include <stdlib.h>
#include <stdint.h>
#include <sys/types.h>
#include <fcntl.h>
#include <unistd.h>
#include "samtools.pysam.h"
#include "bcftools.pysam.h"
#ifdef _OPENMP
#include <omp.h>
#endif /* _OPENMP */

#if defined(PYREX_WITHOUT_ASSERTIONS) && !defined(CYTHON_WITHOUT_ASSERTIONS)
#define CYTHON_WITHOUT_ASSERTIONS
#endif

typedef struct {PyObject **p; const char *s; const Py_ssize_t n; const char* encoding;
                const char is_unicode; const char is_str; const char intern; } __Pyx_StringTabEntry;

#define __PYX_DEFAULT_STRING_ENCODING_IS_ASCII 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_UTF8 0
#define __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT (PY_MAJOR_VERSION >= 3 && __PYX_DEFAULT_STRING_ENCODING_IS_UTF8)
#define __PYX_DEFAULT_STRING_ENCODING ""
#define __Pyx_PyObject_FromString __Pyx_PyBytes_FromString
#define __Pyx_PyObject_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#define __Pyx_uchar_cast(c) ((unsigned char)c)
#define __Pyx_long_cast(x) ((long)x)
#define __Pyx_fits_Py_ssize_t(v, type, is_signed)  (\
    (sizeof(type) < sizeof(Py_ssize_t))  ||\
    (sizeof(type) > sizeof(Py_ssize_t) &&\
          likely(v < (type)PY_SSIZE_T_MAX ||\
                 v == (type)PY_SSIZE_T_MAX)  &&\
          (!is_signed || likely(v > (type)PY_SSIZE_T_MIN ||\
                                v == (type)PY_SSIZE_T_MIN)))  ||\
    (sizeof(type) == sizeof(Py_ssize_t) &&\
          (is_signed || likely(v < (type)PY_SSIZE_T_MAX ||\
                               v == (type)PY_SSIZE_T_MAX)))  )
static CYTHON_INLINE int __Pyx_is_valid_index(Py_ssize_t i, Py_ssize_t limit) {
    return (size_t) i < (size_t) limit;
}
#if defined (__cplusplus) && __cplusplus >= 201103L
    #include <cstdlib>
    #define __Pyx_sst_abs(value) std::abs(value)
#elif SIZEOF_INT >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) abs(value)
#elif SIZEOF_LONG >= SIZEOF_SIZE_T
    #define __Pyx_sst_abs(value) labs(value)
#elif defined (_MSC_VER)
    #define __Pyx_sst_abs(value) ((Py_ssize_t)_abs64(value))
#elif defined (__STDC_VERSION__) && __STDC_VERSION__ >= 199901L
    #define __Pyx_sst_abs(value) llabs(value)
#elif defined (__GNUC__)
    #define __Pyx_sst_abs(value) __builtin_llabs(value)
#else
    #define __Pyx_sst_abs(value) ((value<0) ? -value : value)
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject*);
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject*, Py_ssize_t* length);
#define __Pyx_PyByteArray_FromString(s) PyByteArray_FromStringAndSize((const char*)s, strlen((const char*)s))
#define __Pyx_PyByteArray_FromStringAndSize(s, l) PyByteArray_FromStringAndSize((const char*)s, l)
#define __Pyx_PyBytes_FromString        PyBytes_FromString
#define __Pyx_PyBytes_FromStringAndSize PyBytes_FromStringAndSize
static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char*);
#if PY_MAJOR_VERSION < 3
    #define __Pyx_PyStr_FromString        __Pyx_PyBytes_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyBytes_FromStringAndSize
#else
    #define __Pyx_PyStr_FromString        __Pyx_PyUnicode_FromString
    #define __Pyx_PyStr_FromStringAndSize __Pyx_PyUnicode_FromStringAndSize
#endif
#define __Pyx_PyBytes_AsWritableString(s)     ((char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableSString(s)    ((signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsWritableUString(s)    ((unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsString(s)     ((const char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsSString(s)    ((const signed char*) PyBytes_AS_STRING(s))
#define __Pyx_PyBytes_AsUString(s)    ((const unsigned char*) PyBytes_AS_STRING(s))
#define __Pyx_PyObject_AsWritableString(s)    ((char*)(__pyx_uintptr_t) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableSString(s)    ((signed char*)(__pyx_uintptr_t) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsWritableUString(s)    ((unsigned char*)(__pyx_uintptr_t) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsSString(s)    ((const signed char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_AsUString(s)    ((const unsigned char*) __Pyx_PyObject_AsString(s))
#define __Pyx_PyObject_FromCString(s)  __Pyx_PyObject_FromString((const char*)s)
#define __Pyx_PyBytes_FromCString(s)   __Pyx_PyBytes_FromString((const char*)s)
#define __Pyx_PyByteArray_FromCString(s)   __Pyx_PyByteArray_FromString((const char*)s)
#define __Pyx_PyStr_FromCString(s)     __Pyx_PyStr_FromString((const char*)s)
#define __Pyx_PyUnicode_FromCString(s) __Pyx_PyUnicode_FromString((const char*)s)
#if CYTHON_COMPILING_IN_LIMITED_API
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const wchar_t *u)
{
    const wchar_t *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#else
static CYTHON_INLINE size_t __Pyx_Py_UNICODE_strlen(const Py_UNICODE *u)
{
    const Py_UNICODE *u_end = u;
    while (*u_end++) ;
    return (size_t)(u_end - u - 1);
}
#endif
#define __Pyx_PyUnicode_FromOrdinal(o)       PyUnicode_FromOrdinal((int)o)
#define __Pyx_PyUnicode_FromUnicode(u)       PyUnicode_FromUnicode(u, __Pyx_Py_UNICODE_strlen(u))
#define __Pyx_PyUnicode_FromUnicodeAndLength PyUnicode_FromUnicode
#define __Pyx_PyUnicode_AsUnicode            PyUnicode_AsUnicode
#define __Pyx_NewRef(obj) (Py_INCREF(obj), obj)
#define __Pyx_Owned_Py_None(b) __Pyx_NewRef(Py_None)
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b);
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject*);
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject*);
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x);
#define __Pyx_PySequence_Tuple(obj)\
    (likely(PyTuple_CheckExact(obj)) ? __Pyx_NewRef(obj) : PySequence_Tuple(obj))
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject*);
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t);
static CYTHON_INLINE Py_hash_t __Pyx_PyIndex_AsHash_t(PyObject*);
#if CYTHON_ASSUME_SAFE_MACROS
#define __pyx_PyFloat_AsDouble(x) (PyFloat_CheckExact(x) ? PyFloat_AS_DOUBLE(x) : PyFloat_AsDouble(x))
#else
#define __pyx_PyFloat_AsDouble(x) PyFloat_AsDouble(x)
#endif
#define __pyx_PyFloat_AsFloat(x) ((float) __pyx_PyFloat_AsDouble(x))
#if PY_MAJOR_VERSION >= 3
#define __Pyx_PyNumber_Int(x) (PyLong_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Long(x))
#else
#define __Pyx_PyNumber_Int(x) (PyInt_CheckExact(x) ? __Pyx_NewRef(x) : PyNumber_Int(x))
#endif
#if CYTHON_USE_PYLONG_INTERNALS
  #if PY_VERSION_HEX >= 0x030C00A7
  #ifndef _PyLong_SIGN_MASK
    #define _PyLong_SIGN_MASK 3
  #endif
  #ifndef _PyLong_NON_SIZE_BITS
    #define _PyLong_NON_SIZE_BITS 3
  #endif
  #define __Pyx_PyLong_Sign(x)  (((PyLongObject*)x)->long_value.lv_tag & _PyLong_SIGN_MASK)
  #define __Pyx_PyLong_IsNeg(x)  ((__Pyx_PyLong_Sign(x) & 2) != 0)
  #define __Pyx_PyLong_IsNonNeg(x)  (!__Pyx_PyLong_IsNeg(x))
  #define __Pyx_PyLong_IsZero(x)  (__Pyx_PyLong_Sign(x) & 1)
  #define __Pyx_PyLong_IsPos(x)  (__Pyx_PyLong_Sign(x) == 0)
  #define __Pyx_PyLong_CompactValueUnsigned(x)  (__Pyx_PyLong_Digits(x)[0])
  #define __Pyx_PyLong_DigitCount(x)  ((Py_ssize_t) (((PyLongObject*)x)->long_value.lv_tag >> _PyLong_NON_SIZE_BITS))
  #define __Pyx_PyLong_SignedDigitCount(x)\
        ((1 - (Py_ssize_t) __Pyx_PyLong_Sign(x)) * __Pyx_PyLong_DigitCount(x))
  #if defined(PyUnstable_Long_IsCompact) && defined(PyUnstable_Long_CompactValue)
    #define __Pyx_PyLong_IsCompact(x)     PyUnstable_Long_IsCompact((PyLongObject*) x)
    #define __Pyx_PyLong_CompactValue(x)  PyUnstable_Long_CompactValue((PyLongObject*) x)
  #else
    #define __Pyx_PyLong_IsCompact(x)     (((PyLongObject*)x)->long_value.lv_tag < (2 << _PyLong_NON_SIZE_BITS))
    #define __Pyx_PyLong_CompactValue(x)  ((1 - (Py_ssize_t) __Pyx_PyLong_Sign(x)) * (Py_ssize_t) __Pyx_PyLong_Digits(x)[0])
  #endif
  typedef Py_ssize_t  __Pyx_compact_pylong;
  typedef size_t  __Pyx_compact_upylong;
  #else  // Py < 3.12
  #define __Pyx_PyLong_IsNeg(x)  (Py_SIZE(x) < 0)
  #define __Pyx_PyLong_IsNonNeg(x)  (Py_SIZE(x) >= 0)
  #define __Pyx_PyLong_IsZero(x)  (Py_SIZE(x) == 0)
  #define __Pyx_PyLong_IsPos(x)  (Py_SIZE(x) > 0)
  #define __Pyx_PyLong_CompactValueUnsigned(x)  ((Py_SIZE(x) == 0) ? 0 : __Pyx_PyLong_Digits(x)[0])
  #define __Pyx_PyLong_DigitCount(x)  __Pyx_sst_abs(Py_SIZE(x))
  #define __Pyx_PyLong_SignedDigitCount(x)  Py_SIZE(x)
  #define __Pyx_PyLong_IsCompact(x)  (Py_SIZE(x) == 0 || Py_SIZE(x) == 1 || Py_SIZE(x) == -1)
  #define __Pyx_PyLong_CompactValue(x)\
        ((Py_SIZE(x) == 0) ? (sdigit) 0 : ((Py_SIZE(x) < 0) ? -(sdigit)__Pyx_PyLong_Digits(x)[0] : (sdigit)__Pyx_PyLong_Digits(x)[0]))
  typedef sdigit  __Pyx_compact_pylong;
  typedef digit  __Pyx_compact_upylong;
  #endif
  #if PY_VERSION_HEX >= 0x030C00A5
  #define __Pyx_PyLong_Digits(x)  (((PyLongObject*)x)->long_value.ob_digit)
  #else
  #define __Pyx_PyLong_Digits(x)  (((PyLongObject*)x)->ob_digit)
  #endif
#endif
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
static int __Pyx_sys_getdefaultencoding_not_ascii;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    PyObject* ascii_chars_u = NULL;
    PyObject* ascii_chars_b = NULL;
    const char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    if (strcmp(default_encoding_c, "ascii") == 0) {
        __Pyx_sys_getdefaultencoding_not_ascii = 0;
    } else {
        char ascii_chars[128];
        int c;
        for (c = 0; c < 128; c++) {
            ascii_chars[c] = (char) c;
        }
        __Pyx_sys_getdefaultencoding_not_ascii = 1;
        ascii_chars_u = PyUnicode_DecodeASCII(ascii_chars, 128, NULL);
        if (!ascii_chars_u) goto bad;
        ascii_chars_b = PyUnicode_AsEncodedString(ascii_chars_u, default_encoding_c, NULL);
        if (!ascii_chars_b || !PyBytes_Check(ascii_chars_b) || memcmp(ascii_chars, PyBytes_AS_STRING(ascii_chars_b), 128) != 0) {
            PyErr_Format(
                PyExc_ValueError,
                "This module compiled with c_string_encoding=ascii, but default encoding '%.200s' is not a superset of ascii.",
                default_encoding_c);
            goto bad;
        }
        Py_DECREF(ascii_chars_u);
        Py_DECREF(ascii_chars_b);
    }
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    Py_XDECREF(ascii_chars_u);
    Py_XDECREF(ascii_chars_b);
    return -1;
}
#endif
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT && PY_MAJOR_VERSION >= 3
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_DecodeUTF8(c_str, size, NULL)
#else
#define __Pyx_PyUnicode_FromStringAndSize(c_str, size) PyUnicode_Decode(c_str, size, __PYX_DEFAULT_STRING_ENCODING, NULL)
#if __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
static char* __PYX_DEFAULT_STRING_ENCODING;
static int __Pyx_init_sys_getdefaultencoding_params(void) {
    PyObject* sys;
    PyObject* default_encoding = NULL;
    char* default_encoding_c;
    sys = PyImport_ImportModule("sys");
    if (!sys) goto bad;
    default_encoding = PyObject_CallMethod(sys, (char*) (const char*) "getdefaultencoding", NULL);
    Py_DECREF(sys);
    if (!default_encoding) goto bad;
    default_encoding_c = PyBytes_AsString(default_encoding);
    if (!default_encoding_c) goto bad;
    __PYX_DEFAULT_STRING_ENCODING = (char*) malloc(strlen(default_encoding_c) + 1);
    if (!__PYX_DEFAULT_STRING_ENCODING) goto bad;
    strcpy(__PYX_DEFAULT_STRING_ENCODING, default_encoding_c);
    Py_DECREF(default_encoding);
    return 0;
bad:
    Py_XDECREF(default_encoding);
    return -1;
}
#endif
#endif


/* Test for GCC > 2.95 */
#if defined(__GNUC__)     && (__GNUC__ > 2 || (__GNUC__ == 2 && (__GNUC_MINOR__ > 95)))
  #define likely(x)   __builtin_expect(!!(x), 1)
  #define unlikely(x) __builtin_expect(!!(x), 0)
#else /* !__GNUC__ or GCC < 2.95 */
  #define likely(x)   (x)
  #define unlikely(x) (x)
#endif /* __GNUC__ */
static CYTHON_INLINE void __Pyx_pretend_to_initialize(void* ptr) { (void)ptr; }

#if !CYTHON_USE_MODULE_STATE
static PyObject *__pyx_m = NULL;
#endif
static int __pyx_lineno;
static int __pyx_clineno = 0;
static const char * __pyx_cfilenm = __FILE__;
static const char *__pyx_filename;

/* #### Code section: filename_table ### */

static const char *__pyx_f[] = {
  "pysam/libcutils.pyx",
  "contextvars.pxd",
  "array.pxd",
  "type.pxd",
  "bool.pxd",
  "complex.pxd",
};
/* #### Code section: utility_code_proto_before_types ### */
/* #### Code section: numeric_typedefs ### */
/* #### Code section: complex_type_declarations ### */
/* #### Code section: type_declarations ### */

/*--- Type declarations ---*/
#ifndef _ARRAYARRAY_H
struct arrayobject;
typedef struct arrayobject arrayobject;
#endif
struct __pyx_opt_args_7cpython_11contextvars_get_value;
struct __pyx_opt_args_7cpython_11contextvars_get_value_no_default;

/* "cpython/contextvars.pxd":112
 * 
 * 
 * cdef inline object get_value(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the default value of the context variable,
 */
struct __pyx_opt_args_7cpython_11contextvars_get_value {
  int __pyx_n;
  PyObject *default_value;
};

/* "cpython/contextvars.pxd":129
 * 
 * 
 * cdef inline object get_value_no_default(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the provided default value if no such value was found.
 */
struct __pyx_opt_args_7cpython_11contextvars_get_value_no_default {
  int __pyx_n;
  PyObject *default_value;
};
struct __pyx_opt_args_5pysam_9libcutils_parse_region;
struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array;
struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring;
struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring;
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str;
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_bytes;
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str_w_len;
struct __pyx_opt_args_5pysam_9libcutils_force_str;
struct __pyx_opt_args_5pysam_9libcutils_force_bytes;
struct __pyx_opt_args_5pysam_9libcutils_decode_bytes;

/* "pysam/libcutils.pxd":8
 * from cpython cimport array as c_array
 * 
 * cpdef parse_region(contig=*, start=*, stop=*, region=*, reference=*, end=*)             # <<<<<<<<<<<<<<
 * 
 * cdef int libc_whence_from_io(int whence)
 */
struct __pyx_opt_args_5pysam_9libcutils_parse_region {
  int __pyx_n;
  PyObject *contig;
  PyObject *start;
  PyObject *stop;
  PyObject *region;
  PyObject *reference;
  PyObject *end;
};

/* "pysam/libcutils.pxd":15
 * # Utility functions for quality string conversions
 * 
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=*)             # <<<<<<<<<<<<<<
 * cpdef array_to_qualitystring(c_array.array arr, int offset=*)
 * cpdef qualities_to_qualitystring(qualities, int offset=*)
 */
struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array {
  int __pyx_n;
  int offset;
};

/* "pysam/libcutils.pxd":16
 * 
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=*)
 * cpdef array_to_qualitystring(c_array.array arr, int offset=*)             # <<<<<<<<<<<<<<
 * cpdef qualities_to_qualitystring(qualities, int offset=*)
 * 
 */
struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring {
  int __pyx_n;
  int offset;
};

/* "pysam/libcutils.pxd":17
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=*)
 * cpdef array_to_qualitystring(c_array.array arr, int offset=*)
 * cpdef qualities_to_qualitystring(qualities, int offset=*)             # <<<<<<<<<<<<<<
 * 
 * ########################################################################
 */
struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring {
  int __pyx_n;
  int offset;
};

/* "pysam/libcutils.pxd":29
 * ## Python 3 compatibility functions
 * ########################################################################
 * cdef charptr_to_str(const char *s, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef bytes charptr_to_bytes(const char *s, encoding=*, errors=*)
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=*, errors=*)
 */
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};

/* "pysam/libcutils.pxd":30
 * ########################################################################
 * cdef charptr_to_str(const char *s, encoding=*, errors=*)
 * cdef bytes charptr_to_bytes(const char *s, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=*, errors=*)
 * cdef force_str(object s, encoding=*, errors=*)
 */
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_bytes {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};

/* "pysam/libcutils.pxd":31
 * cdef charptr_to_str(const char *s, encoding=*, errors=*)
 * cdef bytes charptr_to_bytes(const char *s, encoding=*, errors=*)
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef force_str(object s, encoding=*, errors=*)
 * cdef bytes force_bytes(object s, encoding=*, errors=*)
 */
struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str_w_len {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};

/* "pysam/libcutils.pxd":32
 * cdef bytes charptr_to_bytes(const char *s, encoding=*, errors=*)
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=*, errors=*)
 * cdef force_str(object s, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef bytes force_bytes(object s, encoding=*, errors=*)
 * cdef decode_bytes(bytes s, encoding=*, errors=*)
 */
struct __pyx_opt_args_5pysam_9libcutils_force_str {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};

/* "pysam/libcutils.pxd":33
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=*, errors=*)
 * cdef force_str(object s, encoding=*, errors=*)
 * cdef bytes force_bytes(object s, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef decode_bytes(bytes s, encoding=*, errors=*)
 * cdef bytes encode_filename(object filename)
 */
struct __pyx_opt_args_5pysam_9libcutils_force_bytes {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};

/* "pysam/libcutils.pxd":34
 * cdef force_str(object s, encoding=*, errors=*)
 * cdef bytes force_bytes(object s, encoding=*, errors=*)
 * cdef decode_bytes(bytes s, encoding=*, errors=*)             # <<<<<<<<<<<<<<
 * cdef bytes encode_filename(object filename)
 * cdef from_string_and_size(const char *s, size_t length)
 */
struct __pyx_opt_args_5pysam_9libcutils_decode_bytes {
  int __pyx_n;
  PyObject *encoding;
  PyObject *errors;
};
/* #### Code section: utility_code_proto ### */

/* --- Runtime support code (head) --- */
/* Refnanny.proto */
#ifndef CYTHON_REFNANNY
  #define CYTHON_REFNANNY 0
#endif
#if CYTHON_REFNANNY
  typedef struct {
    void (*INCREF)(void*, PyObject*, Py_ssize_t);
    void (*DECREF)(void*, PyObject*, Py_ssize_t);
    void (*GOTREF)(void*, PyObject*, Py_ssize_t);
    void (*GIVEREF)(void*, PyObject*, Py_ssize_t);
    void* (*SetupContext)(const char*, Py_ssize_t, const char*);
    void (*FinishContext)(void**);
  } __Pyx_RefNannyAPIStruct;
  static __Pyx_RefNannyAPIStruct *__Pyx_RefNanny = NULL;
  static __Pyx_RefNannyAPIStruct *__Pyx_RefNannyImportAPI(const char *modname);
  #define __Pyx_RefNannyDeclarations void *__pyx_refnanny = NULL;
#ifdef WITH_THREAD
  #define __Pyx_RefNannySetupContext(name, acquire_gil)\
          if (acquire_gil) {\
              PyGILState_STATE __pyx_gilstate_save = PyGILState_Ensure();\
              __pyx_refnanny = __Pyx_RefNanny->SetupContext((name), (__LINE__), (__FILE__));\
              PyGILState_Release(__pyx_gilstate_save);\
          } else {\
              __pyx_refnanny = __Pyx_RefNanny->SetupContext((name), (__LINE__), (__FILE__));\
          }
  #define __Pyx_RefNannyFinishContextNogil() {\
              PyGILState_STATE __pyx_gilstate_save = PyGILState_Ensure();\
              __Pyx_RefNannyFinishContext();\
              PyGILState_Release(__pyx_gilstate_save);\
          }
#else
  #define __Pyx_RefNannySetupContext(name, acquire_gil)\
          __pyx_refnanny = __Pyx_RefNanny->SetupContext((name), (__LINE__), (__FILE__))
  #define __Pyx_RefNannyFinishContextNogil() __Pyx_RefNannyFinishContext()
#endif
  #define __Pyx_RefNannyFinishContextNogil() {\
              PyGILState_STATE __pyx_gilstate_save = PyGILState_Ensure();\
              __Pyx_RefNannyFinishContext();\
              PyGILState_Release(__pyx_gilstate_save);\
          }
  #define __Pyx_RefNannyFinishContext()\
          __Pyx_RefNanny->FinishContext(&__pyx_refnanny)
  #define __Pyx_INCREF(r)  __Pyx_RefNanny->INCREF(__pyx_refnanny, (PyObject *)(r), (__LINE__))
  #define __Pyx_DECREF(r)  __Pyx_RefNanny->DECREF(__pyx_refnanny, (PyObject *)(r), (__LINE__))
  #define __Pyx_GOTREF(r)  __Pyx_RefNanny->GOTREF(__pyx_refnanny, (PyObject *)(r), (__LINE__))
  #define __Pyx_GIVEREF(r) __Pyx_RefNanny->GIVEREF(__pyx_refnanny, (PyObject *)(r), (__LINE__))
  #define __Pyx_XINCREF(r)  do { if((r) == NULL); else {__Pyx_INCREF(r); }} while(0)
  #define __Pyx_XDECREF(r)  do { if((r) == NULL); else {__Pyx_DECREF(r); }} while(0)
  #define __Pyx_XGOTREF(r)  do { if((r) == NULL); else {__Pyx_GOTREF(r); }} while(0)
  #define __Pyx_XGIVEREF(r) do { if((r) == NULL); else {__Pyx_GIVEREF(r);}} while(0)
#else
  #define __Pyx_RefNannyDeclarations
  #define __Pyx_RefNannySetupContext(name, acquire_gil)
  #define __Pyx_RefNannyFinishContextNogil()
  #define __Pyx_RefNannyFinishContext()
  #define __Pyx_INCREF(r) Py_INCREF(r)
  #define __Pyx_DECREF(r) Py_DECREF(r)
  #define __Pyx_GOTREF(r)
  #define __Pyx_GIVEREF(r)
  #define __Pyx_XINCREF(r) Py_XINCREF(r)
  #define __Pyx_XDECREF(r) Py_XDECREF(r)
  #define __Pyx_XGOTREF(r)
  #define __Pyx_XGIVEREF(r)
#endif
#define __Pyx_Py_XDECREF_SET(r, v) do {\
        PyObject *tmp = (PyObject *) r;\
        r = v; Py_XDECREF(tmp);\
    } while (0)
#define __Pyx_XDECREF_SET(r, v) do {\
        PyObject *tmp = (PyObject *) r;\
        r = v; __Pyx_XDECREF(tmp);\
    } while (0)
#define __Pyx_DECREF_SET(r, v) do {\
        PyObject *tmp = (PyObject *) r;\
        r = v; __Pyx_DECREF(tmp);\
    } while (0)
#define __Pyx_CLEAR(r)    do { PyObject* tmp = ((PyObject*)(r)); r = NULL; __Pyx_DECREF(tmp);} while(0)
#define __Pyx_XCLEAR(r)   do { if((r) != NULL) {PyObject* tmp = ((PyObject*)(r)); r = NULL; __Pyx_DECREF(tmp);}} while(0)

/* PyErrExceptionMatches.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyErr_ExceptionMatches(err) __Pyx_PyErr_ExceptionMatchesInState(__pyx_tstate, err)
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err);
#else
#define __Pyx_PyErr_ExceptionMatches(err)  PyErr_ExceptionMatches(err)
#endif

/* PyThreadStateGet.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyThreadState_declare  PyThreadState *__pyx_tstate;
#define __Pyx_PyThreadState_assign  __pyx_tstate = __Pyx_PyThreadState_Current;
#if PY_VERSION_HEX >= 0x030C00A6
#define __Pyx_PyErr_Occurred()  (__pyx_tstate->current_exception != NULL)
#define __Pyx_PyErr_CurrentExceptionType()  (__pyx_tstate->current_exception ? (PyObject*) Py_TYPE(__pyx_tstate->current_exception) : (PyObject*) NULL)
#else
#define __Pyx_PyErr_Occurred()  (__pyx_tstate->curexc_type != NULL)
#define __Pyx_PyErr_CurrentExceptionType()  (__pyx_tstate->curexc_type)
#endif
#else
#define __Pyx_PyThreadState_declare
#define __Pyx_PyThreadState_assign
#define __Pyx_PyErr_Occurred()  (PyErr_Occurred() != NULL)
#define __Pyx_PyErr_CurrentExceptionType()  PyErr_Occurred()
#endif

/* PyErrFetchRestore.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_PyErr_Clear() __Pyx_ErrRestore(NULL, NULL, NULL)
#define __Pyx_ErrRestoreWithState(type, value, tb)  __Pyx_ErrRestoreInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)    __Pyx_ErrFetchInState(PyThreadState_GET(), type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  __Pyx_ErrRestoreInState(__pyx_tstate, type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)    __Pyx_ErrFetchInState(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX < 0x030C00A6
#define __Pyx_PyErr_SetNone(exc) (Py_INCREF(exc), __Pyx_ErrRestore((exc), NULL, NULL))
#else
#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
#endif
#else
#define __Pyx_PyErr_Clear() PyErr_Clear()
#define __Pyx_PyErr_SetNone(exc) PyErr_SetNone(exc)
#define __Pyx_ErrRestoreWithState(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchWithState(type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestoreInState(tstate, type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetchInState(tstate, type, value, tb)  PyErr_Fetch(type, value, tb)
#define __Pyx_ErrRestore(type, value, tb)  PyErr_Restore(type, value, tb)
#define __Pyx_ErrFetch(type, value, tb)  PyErr_Fetch(type, value, tb)
#endif

/* PyObjectGetAttrStr.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStr(PyObject* obj, PyObject* attr_name);
#else
#define __Pyx_PyObject_GetAttrStr(o,n) PyObject_GetAttr(o,n)
#endif

/* PyObjectGetAttrStrNoError.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStrNoError(PyObject* obj, PyObject* attr_name);

/* GetBuiltinName.proto */
static PyObject *__Pyx_GetBuiltinName(PyObject *name);

/* TupleAndListFromArray.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyList_FromArray(PyObject *const *src, Py_ssize_t n);
static CYTHON_INLINE PyObject* __Pyx_PyTuple_FromArray(PyObject *const *src, Py_ssize_t n);
#endif

/* IncludeStringH.proto */
#include <string.h>

/* BytesEquals.proto */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals);

/* UnicodeEquals.proto */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals);

/* fastcall.proto */
#if CYTHON_AVOID_BORROWED_REFS
    #define __Pyx_Arg_VARARGS(args, i) PySequence_GetItem(args, i)
#elif CYTHON_ASSUME_SAFE_MACROS
    #define __Pyx_Arg_VARARGS(args, i) PyTuple_GET_ITEM(args, i)
#else
    #define __Pyx_Arg_VARARGS(args, i) PyTuple_GetItem(args, i)
#endif
#if CYTHON_AVOID_BORROWED_REFS
    #define __Pyx_Arg_NewRef_VARARGS(arg) __Pyx_NewRef(arg)
    #define __Pyx_Arg_XDECREF_VARARGS(arg) Py_XDECREF(arg)
#else
    #define __Pyx_Arg_NewRef_VARARGS(arg) arg // no-op
    #define __Pyx_Arg_XDECREF_VARARGS(arg) // no-op - arg is borrowed
#endif
#define __Pyx_NumKwargs_VARARGS(kwds) PyDict_Size(kwds)
#define __Pyx_KwValues_VARARGS(args, nargs) NULL
#define __Pyx_GetKwValue_VARARGS(kw, kwvalues, s) __Pyx_PyDict_GetItemStrWithError(kw, s)
#define __Pyx_KwargsAsDict_VARARGS(kw, kwvalues) PyDict_Copy(kw)
#if CYTHON_METH_FASTCALL
    #define __Pyx_Arg_FASTCALL(args, i) args[i]
    #define __Pyx_NumKwargs_FASTCALL(kwds) PyTuple_GET_SIZE(kwds)
    #define __Pyx_KwValues_FASTCALL(args, nargs) ((args) + (nargs))
    static CYTHON_INLINE PyObject * __Pyx_GetKwValue_FASTCALL(PyObject *kwnames, PyObject *const *kwvalues, PyObject *s);
    #define __Pyx_KwargsAsDict_FASTCALL(kw, kwvalues) _PyStack_AsDict(kwvalues, kw)
    #define __Pyx_Arg_NewRef_FASTCALL(arg) arg // no-op, __Pyx_Arg_FASTCALL is direct and this needs
    #define __Pyx_Arg_XDECREF_FASTCALL(arg)  // no-op - arg was returned from array
#else
    #define __Pyx_Arg_FASTCALL __Pyx_Arg_VARARGS
    #define __Pyx_NumKwargs_FASTCALL __Pyx_NumKwargs_VARARGS
    #define __Pyx_KwValues_FASTCALL __Pyx_KwValues_VARARGS
    #define __Pyx_GetKwValue_FASTCALL __Pyx_GetKwValue_VARARGS
    #define __Pyx_KwargsAsDict_FASTCALL __Pyx_KwargsAsDict_VARARGS
    #define __Pyx_Arg_NewRef_FASTCALL(arg) __Pyx_Arg_NewRef_VARARGS(arg)
    #define __Pyx_Arg_XDECREF_FASTCALL(arg) __Pyx_Arg_XDECREF_VARARGS(arg)
#endif
#if CYTHON_COMPILING_IN_CPYTHON && CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
#define __Pyx_ArgsSlice_VARARGS(args, start, stop) __Pyx_PyTuple_FromArray(&__Pyx_Arg_VARARGS(args, start), stop - start)
#define __Pyx_ArgsSlice_FASTCALL(args, start, stop) __Pyx_PyTuple_FromArray(&__Pyx_Arg_FASTCALL(args, start), stop - start)
#else
#define __Pyx_ArgsSlice_VARARGS(args, start, stop) PyTuple_GetSlice(args, start, stop)
#define __Pyx_ArgsSlice_FASTCALL(args, start, stop) PyTuple_GetSlice(args, start, stop)
#endif

/* ListCompAppend.proto */
#if CYTHON_USE_PYLIST_INTERNALS && CYTHON_ASSUME_SAFE_MACROS
static CYTHON_INLINE int __Pyx_ListComp_Append(PyObject* list, PyObject* x) {
    PyListObject* L = (PyListObject*) list;
    Py_ssize_t len = Py_SIZE(list);
    if (likely(L->allocated > len)) {
        Py_INCREF(x);
        PyList_SET_ITEM(list, len, x);
        __Pyx_SET_SIZE(list, len + 1);
        return 0;
    }
    return PyList_Append(list, x);
}
#else
#define __Pyx_ListComp_Append(L,x) PyList_Append(L,x)
#endif

/* PyObjectCall.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw);
#else
#define __Pyx_PyObject_Call(func, arg, kw) PyObject_Call(func, arg, kw)
#endif

/* RaiseDoubleKeywords.proto */
static void __Pyx_RaiseDoubleKeywordsError(const char* func_name, PyObject* kw_name);

/* ParseKeywords.proto */
static int __Pyx_ParseOptionalKeywords(PyObject *kwds, PyObject *const *kwvalues,
    PyObject **argnames[],
    PyObject *kwds2, PyObject *values[], Py_ssize_t num_pos_args,
    const char* function_name);

/* RaiseArgTupleInvalid.proto */
static void __Pyx_RaiseArgtupleInvalid(const char* func_name, int exact,
    Py_ssize_t num_min, Py_ssize_t num_max, Py_ssize_t num_found);

/* GetItemInt.proto */
#define __Pyx_GetItemInt(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Fast(o, (Py_ssize_t)i, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL) :\
               __Pyx_GetItemInt_Generic(o, to_py_func(i))))
#define __Pyx_GetItemInt_List(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_List_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "list index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
#define __Pyx_GetItemInt_Tuple(o, i, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_GetItemInt_Tuple_Fast(o, (Py_ssize_t)i, wraparound, boundscheck) :\
    (PyErr_SetString(PyExc_IndexError, "tuple index out of range"), (PyObject*)NULL))
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              int wraparound, int boundscheck);
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j);
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i,
                                                     int is_list, int wraparound, int boundscheck);

/* SetItemInt.proto */
#define __Pyx_SetItemInt(o, i, v, type, is_signed, to_py_func, is_list, wraparound, boundscheck)\
    (__Pyx_fits_Py_ssize_t(i, type, is_signed) ?\
    __Pyx_SetItemInt_Fast(o, (Py_ssize_t)i, v, is_list, wraparound, boundscheck) :\
    (is_list ? (PyErr_SetString(PyExc_IndexError, "list assignment index out of range"), -1) :\
               __Pyx_SetItemInt_Generic(o, to_py_func(i), v)))
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v);
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v,
                                               int is_list, int wraparound, int boundscheck);

/* PyFunctionFastCall.proto */
#if CYTHON_FAST_PYCALL
#if !CYTHON_VECTORCALL
#define __Pyx_PyFunction_FastCall(func, args, nargs)\
    __Pyx_PyFunction_FastCallDict((func), (args), (nargs), NULL)
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs);
#endif
#define __Pyx_BUILD_ASSERT_EXPR(cond)\
    (sizeof(char [1 - 2*!(cond)]) - 1)
#ifndef Py_MEMBER_SIZE
#define Py_MEMBER_SIZE(type, member) sizeof(((type *)0)->member)
#endif
#if !CYTHON_VECTORCALL
#if PY_VERSION_HEX >= 0x03080000
  #include "frameobject.h"
#if PY_VERSION_HEX >= 0x030b00a6 && !CYTHON_COMPILING_IN_LIMITED_API
  #ifndef Py_BUILD_CORE
    #define Py_BUILD_CORE 1
  #endif
  #include "internal/pycore_frame.h"
#endif
  #define __Pxy_PyFrame_Initialize_Offsets()
  #define __Pyx_PyFrame_GetLocalsplus(frame)  ((frame)->f_localsplus)
#else
  static size_t __pyx_pyframe_localsplus_offset = 0;
  #include "frameobject.h"
  #define __Pxy_PyFrame_Initialize_Offsets()\
    ((void)__Pyx_BUILD_ASSERT_EXPR(sizeof(PyFrameObject) == offsetof(PyFrameObject, f_localsplus) + Py_MEMBER_SIZE(PyFrameObject, f_localsplus)),\
     (void)(__pyx_pyframe_localsplus_offset = ((size_t)PyFrame_Type.tp_basicsize) - Py_MEMBER_SIZE(PyFrameObject, f_localsplus)))
  #define __Pyx_PyFrame_GetLocalsplus(frame)\
    (assert(__pyx_pyframe_localsplus_offset), (PyObject **)(((char *)(frame)) + __pyx_pyframe_localsplus_offset))
#endif
#endif
#endif

/* PyObjectCallMethO.proto */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg);
#endif

/* PyObjectFastCall.proto */
#define __Pyx_PyObject_FastCall(func, args, nargs)  __Pyx_PyObject_FastCallDict(func, args, (size_t)(nargs), NULL)
static CYTHON_INLINE PyObject* __Pyx_PyObject_FastCallDict(PyObject *func, PyObject **args, size_t nargs, PyObject *kwargs);

/* ArgTypeTest.proto */
#define __Pyx_ArgTypeTest(obj, type, none_allowed, name, exact)\
    ((likely(__Pyx_IS_TYPE(obj, type) | (none_allowed && (obj == Py_None)))) ? 1 :\
        __Pyx__ArgTypeTest(obj, type, name, exact))
static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact);

/* ExtTypeTest.proto */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type);

/* PyObjectCallOneArg.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg);

/* ObjectGetItem.proto */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject *key);
#else
#define __Pyx_PyObject_GetItem(obj, key)  PyObject_GetItem(obj, key)
#endif

/* RaiseUnexpectedTypeError.proto */
static int __Pyx_RaiseUnexpectedTypeError(const char *expected, PyObject *obj);

/* PyDictVersioning.proto */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
#define __PYX_DICT_VERSION_INIT  ((PY_UINT64_T) -1)
#define __PYX_GET_DICT_VERSION(dict)  (((PyDictObject*)(dict))->ma_version_tag)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)\
    (version_var) = __PYX_GET_DICT_VERSION(dict);\
    (cache_var) = (value);
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP) {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    if (likely(__PYX_GET_DICT_VERSION(DICT) == __pyx_dict_version)) {\
        (VAR) = __pyx_dict_cached_value;\
    } else {\
        (VAR) = __pyx_dict_cached_value = (LOOKUP);\
        __pyx_dict_version = __PYX_GET_DICT_VERSION(DICT);\
    }\
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj);
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj);
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version);
#else
#define __PYX_GET_DICT_VERSION(dict)  (0)
#define __PYX_UPDATE_DICT_CACHE(dict, value, cache_var, version_var)
#define __PYX_PY_DICT_LOOKUP_IF_MODIFIED(VAR, DICT, LOOKUP)  (VAR) = (LOOKUP);
#endif

/* GetModuleGlobalName.proto */
#if CYTHON_USE_DICT_VERSIONS
#define __Pyx_GetModuleGlobalName(var, name)  do {\
    static PY_UINT64_T __pyx_dict_version = 0;\
    static PyObject *__pyx_dict_cached_value = NULL;\
    (var) = (likely(__pyx_dict_version == __PYX_GET_DICT_VERSION(__pyx_d))) ?\
        (likely(__pyx_dict_cached_value) ? __Pyx_NewRef(__pyx_dict_cached_value) : __Pyx_GetBuiltinName(name)) :\
        __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
} while(0)
#define __Pyx_GetModuleGlobalNameUncached(var, name)  do {\
    PY_UINT64_T __pyx_dict_version;\
    PyObject *__pyx_dict_cached_value;\
    (var) = __Pyx__GetModuleGlobalName(name, &__pyx_dict_version, &__pyx_dict_cached_value);\
} while(0)
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value);
#else
#define __Pyx_GetModuleGlobalName(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
#define __Pyx_GetModuleGlobalNameUncached(var, name)  (var) = __Pyx__GetModuleGlobalName(name)
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name);
#endif

/* RaiseException.proto */
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause);

/* GetTopmostException.proto */
#if CYTHON_USE_EXC_INFO_STACK && CYTHON_FAST_THREAD_STATE
static _PyErr_StackItem * __Pyx_PyErr_GetTopmostException(PyThreadState *tstate);
#endif

/* SaveResetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSave(type, value, tb)  __Pyx__ExceptionSave(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#define __Pyx_ExceptionReset(type, value, tb)  __Pyx__ExceptionReset(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb);
#else
#define __Pyx_ExceptionSave(type, value, tb)   PyErr_GetExcInfo(type, value, tb)
#define __Pyx_ExceptionReset(type, value, tb)  PyErr_SetExcInfo(type, value, tb)
#endif

/* GetException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_GetException(type, value, tb)  __Pyx__GetException(__pyx_tstate, type, value, tb)
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* PySequenceContains.proto */
static CYTHON_INLINE int __Pyx_PySequence_ContainsTF(PyObject* item, PyObject* seq, int eq) {
    int result = PySequence_Contains(seq, item);
    return unlikely(result < 0) ? result : (result == (eq == Py_EQ));
}

/* RaiseTooManyValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected);

/* RaiseNeedMoreValuesToUnpack.proto */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index);

/* IterFinish.proto */
static CYTHON_INLINE int __Pyx_IterFinish(void);

/* UnpackItemEndCheck.proto */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected);

/* PyIntBinop.proto */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check);
#else
#define __Pyx_PyInt_SubtractObjC(op1, op2, intval, inplace, zerodivision_check)\
    (inplace ? PyNumber_InPlaceSubtract(op1, op2) : PyNumber_Subtract(op1, op2))
#endif

/* PyObjectLookupSpecial.proto */
#if CYTHON_USE_PYTYPE_LOOKUP && CYTHON_USE_TYPE_SLOTS
#define __Pyx_PyObject_LookupSpecialNoError(obj, attr_name)  __Pyx__PyObject_LookupSpecial(obj, attr_name, 0)
#define __Pyx_PyObject_LookupSpecial(obj, attr_name)  __Pyx__PyObject_LookupSpecial(obj, attr_name, 1)
static CYTHON_INLINE PyObject* __Pyx__PyObject_LookupSpecial(PyObject* obj, PyObject* attr_name, int with_error);
#else
#define __Pyx_PyObject_LookupSpecialNoError(o,n) __Pyx_PyObject_GetAttrStrNoError(o,n)
#define __Pyx_PyObject_LookupSpecial(o,n) __Pyx_PyObject_GetAttrStr(o,n)
#endif

/* SwapException.proto */
#if CYTHON_FAST_THREAD_STATE
#define __Pyx_ExceptionSwap(type, value, tb)  __Pyx__ExceptionSwap(__pyx_tstate, type, value, tb)
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb);
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb);
#endif

/* PyIntCompare.proto */
static CYTHON_INLINE int __Pyx_PyInt_BoolEqObjC(PyObject *op1, PyObject *op2, long intval, long inplace);

/* DictGetItem.proto */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key);
#define __Pyx_PyObject_Dict_GetItem(obj, name)\
    (likely(PyDict_CheckExact(obj)) ?\
     __Pyx_PyDict_GetItem(obj, name) : PyObject_GetItem(obj, name))
#else
#define __Pyx_PyDict_GetItem(d, key) PyObject_GetItem(d, key)
#define __Pyx_PyObject_Dict_GetItem(obj, name)  PyObject_GetItem(obj, name)
#endif

/* IncludeStructmemberH.proto */
#include <structmember.h>

/* FixUpExtensionType.proto */
#if CYTHON_USE_TYPE_SPECS
static int __Pyx_fix_up_extension_type_from_spec(PyType_Spec *spec, PyTypeObject *type);
#endif

/* FetchSharedCythonModule.proto */
static PyObject *__Pyx_FetchSharedCythonABIModule(void);

/* FetchCommonType.proto */
#if !CYTHON_USE_TYPE_SPECS
static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type);
#else
static PyTypeObject* __Pyx_FetchCommonTypeFromSpec(PyObject *module, PyType_Spec *spec, PyObject *bases);
#endif

/* PyMethodNew.proto */
#if CYTHON_COMPILING_IN_LIMITED_API
static PyObject *__Pyx_PyMethod_New(PyObject *func, PyObject *self, PyObject *typ) {
    PyObject *typesModule=NULL, *methodType=NULL, *result=NULL;
    CYTHON_UNUSED_VAR(typ);
    if (!self)
        return __Pyx_NewRef(func);
    typesModule = PyImport_ImportModule("types");
    if (!typesModule) return NULL;
    methodType = PyObject_GetAttrString(typesModule, "MethodType");
    Py_DECREF(typesModule);
    if (!methodType) return NULL;
    result = PyObject_CallFunctionObjArgs(methodType, func, self, NULL);
    Py_DECREF(methodType);
    return result;
}
#elif PY_MAJOR_VERSION >= 3
static PyObject *__Pyx_PyMethod_New(PyObject *func, PyObject *self, PyObject *typ) {
    CYTHON_UNUSED_VAR(typ);
    if (!self)
        return __Pyx_NewRef(func);
    return PyMethod_New(func, self);
}
#else
    #define __Pyx_PyMethod_New PyMethod_New
#endif

/* PyVectorcallFastCallDict.proto */
#if CYTHON_METH_FASTCALL
static CYTHON_INLINE PyObject *__Pyx_PyVectorcall_FastCallDict(PyObject *func, __pyx_vectorcallfunc vc, PyObject *const *args, size_t nargs, PyObject *kw);
#endif

/* CythonFunctionShared.proto */
#define __Pyx_CyFunction_USED
#define __Pyx_CYFUNCTION_STATICMETHOD  0x01
#define __Pyx_CYFUNCTION_CLASSMETHOD   0x02
#define __Pyx_CYFUNCTION_CCLASS        0x04
#define __Pyx_CYFUNCTION_COROUTINE     0x08
#define __Pyx_CyFunction_GetClosure(f)\
    (((__pyx_CyFunctionObject *) (f))->func_closure)
#if PY_VERSION_HEX < 0x030900B1 || CYTHON_COMPILING_IN_LIMITED_API
  #define __Pyx_CyFunction_GetClassObj(f)\
      (((__pyx_CyFunctionObject *) (f))->func_classobj)
#else
  #define __Pyx_CyFunction_GetClassObj(f)\
      ((PyObject*) ((PyCMethodObject *) (f))->mm_class)
#endif
#define __Pyx_CyFunction_SetClassObj(f, classobj)\
    __Pyx__CyFunction_SetClassObj((__pyx_CyFunctionObject *) (f), (classobj))
#define __Pyx_CyFunction_Defaults(type, f)\
    ((type *)(((__pyx_CyFunctionObject *) (f))->defaults))
#define __Pyx_CyFunction_SetDefaultsGetter(f, g)\
    ((__pyx_CyFunctionObject *) (f))->defaults_getter = (g)
typedef struct {
#if CYTHON_COMPILING_IN_LIMITED_API
    PyObject_HEAD
    PyObject *func;
#elif PY_VERSION_HEX < 0x030900B1
    PyCFunctionObject func;
#else
    PyCMethodObject func;
#endif
#if CYTHON_BACKPORT_VECTORCALL
    __pyx_vectorcallfunc func_vectorcall;
#endif
#if PY_VERSION_HEX < 0x030500A0 || CYTHON_COMPILING_IN_LIMITED_API
    PyObject *func_weakreflist;
#endif
    PyObject *func_dict;
    PyObject *func_name;
    PyObject *func_qualname;
    PyObject *func_doc;
    PyObject *func_globals;
    PyObject *func_code;
    PyObject *func_closure;
#if PY_VERSION_HEX < 0x030900B1 || CYTHON_COMPILING_IN_LIMITED_API
    PyObject *func_classobj;
#endif
    void *defaults;
    int defaults_pyobjects;
    size_t defaults_size;  // used by FusedFunction for copying defaults
    int flags;
    PyObject *defaults_tuple;
    PyObject *defaults_kwdict;
    PyObject *(*defaults_getter)(PyObject *);
    PyObject *func_annotations;
    PyObject *func_is_coroutine;
} __pyx_CyFunctionObject;
#define __Pyx_CyFunction_Check(obj)  __Pyx_TypeCheck(obj, __pyx_CyFunctionType)
#define __Pyx_IsCyOrPyCFunction(obj)  __Pyx_TypeCheck2(obj, __pyx_CyFunctionType, &PyCFunction_Type)
#define __Pyx_CyFunction_CheckExact(obj)  __Pyx_IS_TYPE(obj, __pyx_CyFunctionType)
static PyObject *__Pyx_CyFunction_Init(__pyx_CyFunctionObject* op, PyMethodDef *ml,
                                      int flags, PyObject* qualname,
                                      PyObject *closure,
                                      PyObject *module, PyObject *globals,
                                      PyObject* code);
static CYTHON_INLINE void __Pyx__CyFunction_SetClassObj(__pyx_CyFunctionObject* f, PyObject* classobj);
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *m,
                                                         size_t size,
                                                         int pyobjects);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *m,
                                                            PyObject *tuple);
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *m,
                                                             PyObject *dict);
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *m,
                                                              PyObject *dict);
static int __pyx_CyFunction_init(PyObject *module);
#if CYTHON_METH_FASTCALL
static PyObject * __Pyx_CyFunction_Vectorcall_NOARGS(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames);
static PyObject * __Pyx_CyFunction_Vectorcall_O(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames);
static PyObject * __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames);
static PyObject * __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS_METHOD(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames);
#if CYTHON_BACKPORT_VECTORCALL
#define __Pyx_CyFunction_func_vectorcall(f) (((__pyx_CyFunctionObject*)f)->func_vectorcall)
#else
#define __Pyx_CyFunction_func_vectorcall(f) (((PyCFunctionObject*)f)->vectorcall)
#endif
#endif

/* CythonFunction.proto */
static PyObject *__Pyx_CyFunction_New(PyMethodDef *ml,
                                      int flags, PyObject* qualname,
                                      PyObject *closure,
                                      PyObject *module, PyObject *globals,
                                      PyObject* code);

/* RaiseUnboundLocalError.proto */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname);

/* TypeImport.proto */
#ifndef __PYX_HAVE_RT_ImportType_proto_3_0_2
#define __PYX_HAVE_RT_ImportType_proto_3_0_2
#if defined (__STDC_VERSION__) && __STDC_VERSION__ >= 201112L
#include <stdalign.h>
#endif
#if (defined (__STDC_VERSION__) && __STDC_VERSION__ >= 201112L) || __cplusplus >= 201103L
#define __PYX_GET_STRUCT_ALIGNMENT_3_0_2(s) alignof(s)
#else
#define __PYX_GET_STRUCT_ALIGNMENT_3_0_2(s) sizeof(void*)
#endif
enum __Pyx_ImportType_CheckSize_3_0_2 {
   __Pyx_ImportType_CheckSize_Error_3_0_2 = 0,
   __Pyx_ImportType_CheckSize_Warn_3_0_2 = 1,
   __Pyx_ImportType_CheckSize_Ignore_3_0_2 = 2
};
static PyTypeObject *__Pyx_ImportType_3_0_2(PyObject* module, const char *module_name, const char *class_name, size_t size, size_t alignment, enum __Pyx_ImportType_CheckSize_3_0_2 check_size);
#endif

/* Import.proto */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level);

/* ImportDottedModule.proto */
static PyObject *__Pyx_ImportDottedModule(PyObject *name, PyObject *parts_tuple);
#if PY_MAJOR_VERSION >= 3
static PyObject *__Pyx_ImportDottedModule_WalkParts(PyObject *module, PyObject *name, PyObject *parts_tuple);
#endif

/* ImportFrom.proto */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name);

/* PyObjectCallNoArg.proto */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func);

/* CLineInTraceback.proto */
#ifdef CYTHON_CLINE_IN_TRACEBACK
#define __Pyx_CLineForTraceback(tstate, c_line)  (((CYTHON_CLINE_IN_TRACEBACK)) ? c_line : 0)
#else
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line);
#endif

/* CodeObjectCache.proto */
#if !CYTHON_COMPILING_IN_LIMITED_API
typedef struct {
    PyCodeObject* code_object;
    int code_line;
} __Pyx_CodeObjectCacheEntry;
struct __Pyx_CodeObjectCache {
    int count;
    int max_count;
    __Pyx_CodeObjectCacheEntry* entries;
};
static struct __Pyx_CodeObjectCache __pyx_code_cache = {0,0,NULL};
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line);
static PyCodeObject *__pyx_find_code_object(int code_line);
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object);
#endif

/* AddTraceback.proto */
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename);

/* ArrayAPI.proto */
#ifndef _ARRAYARRAY_H
#define _ARRAYARRAY_H
typedef struct arraydescr {
    int typecode;
    int itemsize;
    PyObject * (*getitem)(struct arrayobject *, Py_ssize_t);
    int (*setitem)(struct arrayobject *, Py_ssize_t, PyObject *);
#if PY_MAJOR_VERSION >= 3
    char *formats;
#endif
} arraydescr;
struct arrayobject {
    PyObject_HEAD
    Py_ssize_t ob_size;
    union {
        char *ob_item;
        float *as_floats;
        double *as_doubles;
        int *as_ints;
        unsigned int *as_uints;
        unsigned char *as_uchars;
        signed char *as_schars;
        char *as_chars;
        unsigned long *as_ulongs;
        long *as_longs;
#if PY_MAJOR_VERSION >= 3
        unsigned long long *as_ulonglongs;
        long long *as_longlongs;
#endif
        short *as_shorts;
        unsigned short *as_ushorts;
        Py_UNICODE *as_pyunicodes;
        void *as_voidptr;
    } data;
    Py_ssize_t allocated;
    struct arraydescr *ob_descr;
    PyObject *weakreflist;
#if PY_MAJOR_VERSION >= 3
        int ob_exports;
#endif
};
#ifndef NO_NEWARRAY_INLINE
static CYTHON_INLINE PyObject * newarrayobject(PyTypeObject *type, Py_ssize_t size,
    struct arraydescr *descr) {
    arrayobject *op;
    size_t nbytes;
    if (size < 0) {
        PyErr_BadInternalCall();
        return NULL;
    }
    nbytes = size * descr->itemsize;
    if (nbytes / descr->itemsize != (size_t)size) {
        return PyErr_NoMemory();
    }
    op = (arrayobject *) type->tp_alloc(type, 0);
    if (op == NULL) {
        return NULL;
    }
    op->ob_descr = descr;
    op->allocated = size;
    op->weakreflist = NULL;
    __Pyx_SET_SIZE(op, size);
    if (size <= 0) {
        op->data.ob_item = NULL;
    }
    else {
        op->data.ob_item = PyMem_NEW(char, nbytes);
        if (op->data.ob_item == NULL) {
            Py_DECREF(op);
            return PyErr_NoMemory();
        }
    }
    return (PyObject *) op;
}
#else
PyObject* newarrayobject(PyTypeObject *type, Py_ssize_t size,
    struct arraydescr *descr);
#endif
static CYTHON_INLINE int resize(arrayobject *self, Py_ssize_t n) {
    void *items = (void*) self->data.ob_item;
    PyMem_Resize(items, char, (size_t)(n * self->ob_descr->itemsize));
    if (items == NULL) {
        PyErr_NoMemory();
        return -1;
    }
    self->data.ob_item = (char*) items;
    __Pyx_SET_SIZE(self, n);
    self->allocated = n;
    return 0;
}
static CYTHON_INLINE int resize_smart(arrayobject *self, Py_ssize_t n) {
    void *items = (void*) self->data.ob_item;
    Py_ssize_t newsize;
    if (n < self->allocated && n*4 > self->allocated) {
        __Pyx_SET_SIZE(self, n);
        return 0;
    }
    newsize = n + (n / 2) + 1;
    if (newsize <= n) {
        PyErr_NoMemory();
        return -1;
    }
    PyMem_Resize(items, char, (size_t)(newsize * self->ob_descr->itemsize));
    if (items == NULL) {
        PyErr_NoMemory();
        return -1;
    }
    self->data.ob_item = (char*) items;
    __Pyx_SET_SIZE(self, n);
    self->allocated = newsize;
    return 0;
}
#endif

/* GCCDiagnostics.proto */
#if !defined(__INTEL_COMPILER) && defined(__GNUC__) && (__GNUC__ > 4 || (__GNUC__ == 4 && __GNUC_MINOR__ >= 6))
#define __Pyx_HAS_GCC_DIAGNOSTIC
#endif

/* CIntFromPy.proto */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *);

/* CIntFromPy.proto */
static CYTHON_INLINE char __Pyx_PyInt_As_char(PyObject *);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value);

/* CIntFromPy.proto */
static CYTHON_INLINE int32_t __Pyx_PyInt_As_int32_t(PyObject *);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value);

/* CIntToPy.proto */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int32_t(int32_t value);

/* FormatTypeName.proto */
#if CYTHON_COMPILING_IN_LIMITED_API
typedef PyObject *__Pyx_TypeName;
#define __Pyx_FMT_TYPENAME "%U"
static __Pyx_TypeName __Pyx_PyType_GetName(PyTypeObject* tp);
#define __Pyx_DECREF_TypeName(obj) Py_XDECREF(obj)
#else
typedef const char *__Pyx_TypeName;
#define __Pyx_FMT_TYPENAME "%.200s"
#define __Pyx_PyType_GetName(tp) ((tp)->tp_name)
#define __Pyx_DECREF_TypeName(obj)
#endif

/* CIntFromPy.proto */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *);

/* FastTypeChecks.proto */
#if CYTHON_COMPILING_IN_CPYTHON
#define __Pyx_TypeCheck(obj, type) __Pyx_IsSubtype(Py_TYPE(obj), (PyTypeObject *)type)
#define __Pyx_TypeCheck2(obj, type1, type2) __Pyx_IsAnySubtype2(Py_TYPE(obj), (PyTypeObject *)type1, (PyTypeObject *)type2)
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b);
static CYTHON_INLINE int __Pyx_IsAnySubtype2(PyTypeObject *cls, PyTypeObject *a, PyTypeObject *b);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject *type);
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *type1, PyObject *type2);
#else
#define __Pyx_TypeCheck(obj, type) PyObject_TypeCheck(obj, (PyTypeObject *)type)
#define __Pyx_TypeCheck2(obj, type1, type2) (PyObject_TypeCheck(obj, (PyTypeObject *)type1) || PyObject_TypeCheck(obj, (PyTypeObject *)type2))
#define __Pyx_PyErr_GivenExceptionMatches(err, type) PyErr_GivenExceptionMatches(err, type)
#define __Pyx_PyErr_GivenExceptionMatches2(err, type1, type2) (PyErr_GivenExceptionMatches(err, type1) || PyErr_GivenExceptionMatches(err, type2))
#endif
#define __Pyx_PyErr_ExceptionMatches2(err1, err2)  __Pyx_PyErr_GivenExceptionMatches2(__Pyx_PyErr_CurrentExceptionType(), err1, err2)
#define __Pyx_PyException_Check(obj) __Pyx_TypeCheck(obj, PyExc_Exception)

/* CheckBinaryVersion.proto */
static int __Pyx_check_binary_version(void);

/* FunctionExport.proto */
static int __Pyx_ExportFunction(const char *name, void (*f)(void), const char *sig);

/* InitStrings.proto */
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t);

/* #### Code section: module_declarations ### */
static CYTHON_INLINE double __pyx_f_7cpython_7complex_7complex_4real_real(PyComplexObject *__pyx_v_self); /* proto*/
static CYTHON_INLINE double __pyx_f_7cpython_7complex_7complex_4imag_imag(PyComplexObject *__pyx_v_self); /* proto*/

/* Module declarations from "cython" */

/* Module declarations from "cpython.version" */

/* Module declarations from "__builtin__" */

/* Module declarations from "cpython.type" */

/* Module declarations from "libc.string" */

/* Module declarations from "libc.stdio" */

/* Module declarations from "cpython.object" */

/* Module declarations from "cpython.ref" */

/* Module declarations from "cpython.exc" */

/* Module declarations from "cpython.module" */

/* Module declarations from "cpython.mem" */

/* Module declarations from "cpython.tuple" */

/* Module declarations from "cpython.list" */

/* Module declarations from "cpython.sequence" */

/* Module declarations from "cpython.mapping" */

/* Module declarations from "cpython.iterator" */

/* Module declarations from "cpython.number" */

/* Module declarations from "cpython.int" */

/* Module declarations from "__builtin__" */

/* Module declarations from "cpython.bool" */

/* Module declarations from "cpython.long" */

/* Module declarations from "cpython.float" */

/* Module declarations from "__builtin__" */

/* Module declarations from "cpython.complex" */

/* Module declarations from "cpython.string" */

/* Module declarations from "cpython.unicode" */

/* Module declarations from "cpython.pyport" */

/* Module declarations from "cpython.dict" */

/* Module declarations from "cpython.instance" */

/* Module declarations from "cpython.function" */

/* Module declarations from "cpython.method" */

/* Module declarations from "cpython.weakref" */

/* Module declarations from "cpython.getargs" */

/* Module declarations from "cpython.pythread" */

/* Module declarations from "cpython.pystate" */

/* Module declarations from "cpython.cobject" */

/* Module declarations from "cpython.oldbuffer" */

/* Module declarations from "cpython.set" */

/* Module declarations from "cpython.buffer" */

/* Module declarations from "cpython.bytes" */

/* Module declarations from "cpython.pycapsule" */

/* Module declarations from "cpython.contextvars" */

/* Module declarations from "cpython" */

/* Module declarations from "array" */

/* Module declarations from "cpython.array" */
static CYTHON_INLINE arrayobject *__pyx_f_7cpython_5array_clone(arrayobject *, Py_ssize_t, int); /*proto*/
static CYTHON_INLINE int __pyx_f_7cpython_5array_extend_buffer(arrayobject *, char *, Py_ssize_t); /*proto*/

/* Module declarations from "libc.stdlib" */

/* Module declarations from "libc.stdint" */

/* Module declarations from "posix.types" */

/* Module declarations from "posix.fcntl" */

/* Module declarations from "posix.unistd" */

/* Module declarations from "libcsamtools" */

/* Module declarations from "libcbcftools" */

/* Module declarations from "pysam.libcutils" */
static int __pyx_v_5pysam_9libcutils_MAX_POS;
static PyObject *__pyx_v_5pysam_9libcutils_ERROR_HANDLER = 0;
static PyObject *__pyx_v_5pysam_9libcutils_FILENAME_ENCODING = 0;
static PyObject *__pyx_v_5pysam_9libcutils_TEXT_ENCODING = 0;
static PyObject *__pyx_f_5pysam_9libcutils_parse_region(int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_parse_region *__pyx_optional_args); /*proto*/
static arrayobject *__pyx_f_5pysam_9libcutils_qualitystring_to_array(PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_array_to_qualitystring(arrayobject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_qualities_to_qualitystring(PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_get_encoding_error_handler(int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_set_encoding_error_handler(PyObject *, int __pyx_skip_dispatch); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_force_str(PyObject *, struct __pyx_opt_args_5pysam_9libcutils_force_str *__pyx_optional_args); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_force_bytes(PyObject *, struct __pyx_opt_args_5pysam_9libcutils_force_bytes *__pyx_optional_args); /*proto*/
/* #### Code section: typeinfo ### */
/* #### Code section: before_global_var ### */
#define __Pyx_MODULE_NAME "pysam.libcutils"
extern int __pyx_module_is_main_pysam__libcutils;
int __pyx_module_is_main_pysam__libcutils = 0;

/* Implementation of "pysam.libcutils" */
/* #### Code section: global_var ### */
static PyObject *__pyx_builtin_chr;
static PyObject *__pyx_builtin_TypeError;
static PyObject *__pyx_builtin_ValueError;
static PyObject *__pyx_builtin_OverflowError;
static PyObject *__pyx_builtin_IOError;
static PyObject *__pyx_builtin_open;
static PyObject *__pyx_builtin_UnicodeDecodeError;
static PyObject *__pyx_builtin_MemoryError;
/* #### Code section: string_decls ### */
static const char __pyx_k_[] = "";
static const char __pyx_k_B[] = "B";
static const char __pyx_k_a[] = "a";
static const char __pyx_k_c[] = "-c";
static const char __pyx_k_i[] = "i";
static const char __pyx_k_l[] = "l";
static const char __pyx_k_m[] = "-m";
static const char __pyx_k_n[] = "n";
static const char __pyx_k_o[] = "-o";
static const char __pyx_k_r[] = "r";
static const char __pyx_k__7[] = ":";
static const char __pyx_k__8[] = "-";
static const char __pyx_k_fn[] = "fn";
static const char __pyx_k_io[] = "io";
static const char __pyx_k_os[] = "os";
static const char __pyx_k_rb[] = "rb";
static const char __pyx_k_re[] = "re";
static const char __pyx_k__10[] = "-@";
static const char __pyx_k__11[] = " ";
static const char __pyx_k__14[] = "*";
static const char __pyx_k__15[] = ".";
static const char __pyx_k__33[] = "?";
static const char __pyx_k_all[] = "__all__";
static const char __pyx_k_arg[] = "arg";
static const char __pyx_k_chr[] = "chr";
static const char __pyx_k_end[] = "end";
static const char __pyx_k_inf[] = "inf";
static const char __pyx_k_o_2[] = "-o {}";
static const char __pyx_k_out[] = "out";
static const char __pyx_k_roh[] = "roh";
static const char __pyx_k_sys[] = "sys";
static const char __pyx_k_args[] = "args";
static const char __pyx_k_exit[] = "__exit__";
static const char __pyx_k_main[] = "__main__";
static const char __pyx_k_name[] = "name";
static const char __pyx_k_open[] = "open";
static const char __pyx_k_path[] = "path";
static const char __pyx_k_read[] = "read";
static const char __pyx_k_spec[] = "__spec__";
static const char __pyx_k_stop[] = "stop";
static const char __pyx_k_test[] = "__test__";
static const char __pyx_k_view[] = "view";
static const char __pyx_k_ascii[] = "ascii";
static const char __pyx_k_calmd[] = "calmd";
static const char __pyx_k_cargs[] = "cargs";
static const char __pyx_k_close[] = "close";
static const char __pyx_k_depad[] = "depad";
static const char __pyx_k_enter[] = "__enter__";
static const char __pyx_k_index[] = "index";
static const char __pyx_k_split[] = "split";
static const char __pyx_k_start[] = "start";
static const char __pyx_k_stats[] = "stats";
static const char __pyx_k_types[] = "types";
static const char __pyx_k_utf_8[] = "utf-8";
static const char __pyx_k_codecs[] = "codecs";
static const char __pyx_k_contig[] = "contig";
static const char __pyx_k_decode[] = "decode";
static const char __pyx_k_encode[] = "encode";
static const char __pyx_k_exists[] = "exists";
static const char __pyx_k_extend[] = "extend";
static const char __pyx_k_format[] = "format";
static const char __pyx_k_import[] = "__import__";
static const char __pyx_k_method[] = "method";
static const char __pyx_k_name_2[] = "__name__";
static const char __pyx_k_object[] = "object";
static const char __pyx_k_offset[] = "offset";
static const char __pyx_k_output[] = "--output";
static const char __pyx_k_region[] = "region";
static const char __pyx_k_remove[] = "remove";
static const char __pyx_k_retval[] = "retval";
static const char __pyx_k_strict[] = "strict";
static const char __pyx_k_string[] = "string";
static const char __pyx_k_IOError[] = "IOError";
static const char __pyx_k_collect[] = "_collect";
static const char __pyx_k_mkstemp[] = "mkstemp";
static const char __pyx_k_mpileup[] = "mpileup";
static const char __pyx_k_threads[] = "--threads";
static const char __pyx_k_tobytes[] = "tobytes";
static const char __pyx_k_bcftools[] = "bcftools";
static const char __pyx_k_fsencode[] = "fsencode";
static const char __pyx_k_is_usage[] = "is_usage";
static const char __pyx_k_samtools[] = "samtools";
static const char __pyx_k_stderr_f[] = "stderr_f";
static const char __pyx_k_stderr_h[] = "stderr_h";
static const char __pyx_k_stdout_f[] = "stdout_f";
static const char __pyx_k_stdout_h[] = "stdout_h";
static const char __pyx_k_tempfile[] = "tempfile";
static const char __pyx_k_ARGUMENTS[] = "ARGUMENTS";
static const char __pyx_k_TypeError[] = "TypeError";
static const char __pyx_k_exception[] = "exception";
static const char __pyx_k_input_str[] = "input_str";
static const char __pyx_k_min_shift[] = "--min-shift";
static const char __pyx_k_qualities[] = "qualities";
static const char __pyx_k_reference[] = "reference";
static const char __pyx_k_skip_next[] = "skip_next";
static const char __pyx_k_ValueError[] = "ValueError";
static const char __pyx_k_collection[] = "collection";
static const char __pyx_k_contextlib[] = "contextlib";
static const char __pyx_k_extra_args[] = "extra_args";
static const char __pyx_k_out_stderr[] = "out_stderr";
static const char __pyx_k_out_stdout[] = "out_stdout";
static const char __pyx_k_startswith[] = "startswith";
static const char __pyx_k_MemoryError[] = "MemoryError";
static const char __pyx_k_output_file[] = "--output-file";
static const char __pyx_k_save_stdout[] = "save_stdout";
static const char __pyx_k_catch_stdout[] = "catch_stdout";
static const char __pyx_k_initializing[] = "_initializing";
static const char __pyx_k_is_coroutine[] = "_is_coroutine";
static const char __pyx_k_parse_region[] = "parse_region";
static const char __pyx_k_OverflowError[] = "OverflowError";
static const char __pyx_k_class_getitem[] = "__class_getitem__";
static const char __pyx_k_stdout_option[] = "stdout_option";
static const char __pyx_k_contextmanager[] = "contextmanager";
static const char __pyx_k_latin1_replace[] = "latin1_replace";
static const char __pyx_k_pysam_dispatch[] = "_pysam_dispatch";
static const char __pyx_k_register_error[] = "register_error";
static const char __pyx_k_pysam_libcutils[] = "pysam.libcutils";
static const char __pyx_k_MAP_STDOUT_OPTIONS[] = "MAP_STDOUT_OPTIONS";
static const char __pyx_k_UnicodeDecodeError[] = "UnicodeDecodeError";
static const char __pyx_k_asyncio_coroutines[] = "asyncio.coroutines";
static const char __pyx_k_cline_in_traceback[] = "cline_in_traceback";
static const char __pyx_k_getdefaultencoding[] = "getdefaultencoding";
static const char __pyx_k_pysam_latin1replace[] = "pysam.latin1replace";
static const char __pyx_k_pysam_libcutils_pyx[] = "pysam/libcutils.pyx";
static const char __pyx_k_stop_out_of_range_i[] = "stop out of range (%i)";
static const char __pyx_k_start_out_of_range_i[] = "start out of range (%i)";
static const char __pyx_k_getfilesystemencoding[] = "getfilesystemencoding";
static const char __pyx_k_array_to_qualitystring[] = "array_to_qualitystring";
static const char __pyx_k_qualitystring_to_array[] = "qualitystring_to_array";
static const char __pyx_k_get_encoding_error_handler[] = "get_encoding_error_handler";
static const char __pyx_k_qualities_to_qualitystring[] = "qualities_to_qualitystring";
static const char __pyx_k_set_encoding_error_handler[] = "set_encoding_error_handler";
static const char __pyx_k_No_such_file_or_directory_s[] = "No such file or directory: '%s'";
static const char __pyx_k_pysam_dispatch_locals__collect[] = "_pysam_dispatch.<locals>._collect";
static const char __pyx_k_contig_and_reference_should_not[] = "contig and reference should not both be specified";
static const char __pyx_k_error_while_opening_for_writing[] = "error while opening {} for writing";
static const char __pyx_k_stop_and_end_should_not_both_be[] = "stop and end should not both be specified";
static const char __pyx_k_Argument_must_be_string_bytes_or[] = "Argument must be string, bytes or unicode.";
static const char __pyx_k_contig_reference_and_region_shou[] = "contig/reference and region should not both be specified";
static const char __pyx_k_invalid_coordinates_start_i_stop[] = "invalid coordinates: start (%i) > stop (%i)";
static const char __pyx_k_neither_contig_nor_region_are_gi[] = "neither contig nor region are given";
/* #### Code section: decls ### */
static int __pyx_pf_7cpython_5array_5array___getbuffer__(arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info, CYTHON_UNUSED int __pyx_v_flags); /* proto */
static void __pyx_pf_7cpython_5array_5array_2__releasebuffer__(CYTHON_UNUSED arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_qualitystring_to_array(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_input_str, int __pyx_v_offset); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_2array_to_qualitystring(CYTHON_UNUSED PyObject *__pyx_self, arrayobject *__pyx_v_qualities, int __pyx_v_offset); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_4qualities_to_qualitystring(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_qualities, int __pyx_v_offset); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_6latin1_replace(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_exception); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_8get_encoding_error_handler(CYTHON_UNUSED PyObject *__pyx_self); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_10set_encoding_error_handler(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_name); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_12parse_region(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_contig, PyObject *__pyx_v_start, PyObject *__pyx_v_stop, PyObject *__pyx_v_region, PyObject *__pyx_v_reference, PyObject *__pyx_v_end); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_15_pysam_dispatch__collect(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_fn); /* proto */
static PyObject *__pyx_pf_5pysam_9libcutils_14_pysam_dispatch(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_collection, PyObject *__pyx_v_method, PyObject *__pyx_v_args, PyObject *__pyx_v_catch_stdout, PyObject *__pyx_v_is_usage, PyObject *__pyx_v_save_stdout); /* proto */
/* #### Code section: late_includes ### */
/* #### Code section: module_state ### */
typedef struct {
  PyObject *__pyx_d;
  PyObject *__pyx_b;
  PyObject *__pyx_cython_runtime;
  PyObject *__pyx_empty_tuple;
  PyObject *__pyx_empty_bytes;
  PyObject *__pyx_empty_unicode;
  #ifdef __Pyx_CyFunction_USED
  PyTypeObject *__pyx_CyFunctionType;
  #endif
  #ifdef __Pyx_FusedFunction_USED
  PyTypeObject *__pyx_FusedFunctionType;
  #endif
  #ifdef __Pyx_Generator_USED
  PyTypeObject *__pyx_GeneratorType;
  #endif
  #ifdef __Pyx_IterableCoroutine_USED
  PyTypeObject *__pyx_IterableCoroutineType;
  #endif
  #ifdef __Pyx_Coroutine_USED
  PyTypeObject *__pyx_CoroutineAwaitType;
  #endif
  #ifdef __Pyx_Coroutine_USED
  PyTypeObject *__pyx_CoroutineType;
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  PyTypeObject *__pyx_ptype_7cpython_4type_type;
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  PyTypeObject *__pyx_ptype_7cpython_4bool_bool;
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  PyTypeObject *__pyx_ptype_7cpython_7complex_complex;
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  PyTypeObject *__pyx_ptype_7cpython_5array_array;
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  #if CYTHON_USE_MODULE_STATE
  #endif
  PyObject *__pyx_kp_u_;
  PyObject *__pyx_n_s_ARGUMENTS;
  PyObject *__pyx_kp_u_Argument_must_be_string_bytes_or;
  PyObject *__pyx_n_u_B;
  PyObject *__pyx_n_s_IOError;
  PyObject *__pyx_n_s_MAP_STDOUT_OPTIONS;
  PyObject *__pyx_n_s_MemoryError;
  PyObject *__pyx_kp_u_No_such_file_or_directory_s;
  PyObject *__pyx_n_s_OverflowError;
  PyObject *__pyx_n_s_TypeError;
  PyObject *__pyx_n_s_UnicodeDecodeError;
  PyObject *__pyx_n_s_ValueError;
  PyObject *__pyx_kp_u__10;
  PyObject *__pyx_kp_u__11;
  PyObject *__pyx_n_s__14;
  PyObject *__pyx_kp_u__15;
  PyObject *__pyx_n_s__33;
  PyObject *__pyx_kp_u__7;
  PyObject *__pyx_kp_u__8;
  PyObject *__pyx_n_s_a;
  PyObject *__pyx_n_s_all;
  PyObject *__pyx_n_s_arg;
  PyObject *__pyx_n_s_args;
  PyObject *__pyx_n_s_array_to_qualitystring;
  PyObject *__pyx_n_u_array_to_qualitystring;
  PyObject *__pyx_n_u_ascii;
  PyObject *__pyx_n_s_asyncio_coroutines;
  PyObject *__pyx_n_b_bcftools;
  PyObject *__pyx_n_u_bcftools;
  PyObject *__pyx_kp_u_c;
  PyObject *__pyx_n_u_calmd;
  PyObject *__pyx_n_s_cargs;
  PyObject *__pyx_n_s_catch_stdout;
  PyObject *__pyx_n_s_chr;
  PyObject *__pyx_n_s_class_getitem;
  PyObject *__pyx_n_s_cline_in_traceback;
  PyObject *__pyx_n_s_close;
  PyObject *__pyx_n_s_codecs;
  PyObject *__pyx_n_s_collect;
  PyObject *__pyx_n_s_collection;
  PyObject *__pyx_n_s_contextlib;
  PyObject *__pyx_n_s_contextmanager;
  PyObject *__pyx_n_s_contig;
  PyObject *__pyx_kp_u_contig_and_reference_should_not;
  PyObject *__pyx_kp_u_contig_reference_and_region_shou;
  PyObject *__pyx_n_s_decode;
  PyObject *__pyx_n_u_depad;
  PyObject *__pyx_n_s_encode;
  PyObject *__pyx_n_s_end;
  PyObject *__pyx_n_s_enter;
  PyObject *__pyx_kp_u_error_while_opening_for_writing;
  PyObject *__pyx_n_s_exception;
  PyObject *__pyx_n_s_exists;
  PyObject *__pyx_n_s_exit;
  PyObject *__pyx_n_s_extend;
  PyObject *__pyx_n_s_extra_args;
  PyObject *__pyx_n_s_fn;
  PyObject *__pyx_n_s_format;
  PyObject *__pyx_n_s_fsencode;
  PyObject *__pyx_n_s_get_encoding_error_handler;
  PyObject *__pyx_n_u_get_encoding_error_handler;
  PyObject *__pyx_n_s_getdefaultencoding;
  PyObject *__pyx_n_s_getfilesystemencoding;
  PyObject *__pyx_n_s_i;
  PyObject *__pyx_n_s_import;
  PyObject *__pyx_n_b_index;
  PyObject *__pyx_n_u_index;
  PyObject *__pyx_n_s_inf;
  PyObject *__pyx_n_s_initializing;
  PyObject *__pyx_n_s_input_str;
  PyObject *__pyx_kp_u_invalid_coordinates_start_i_stop;
  PyObject *__pyx_n_s_io;
  PyObject *__pyx_n_s_is_coroutine;
  PyObject *__pyx_n_s_is_usage;
  PyObject *__pyx_n_s_l;
  PyObject *__pyx_n_s_latin1_replace;
  PyObject *__pyx_kp_u_m;
  PyObject *__pyx_n_s_main;
  PyObject *__pyx_n_s_method;
  PyObject *__pyx_kp_u_min_shift;
  PyObject *__pyx_n_s_mkstemp;
  PyObject *__pyx_n_u_mpileup;
  PyObject *__pyx_n_s_n;
  PyObject *__pyx_n_s_name;
  PyObject *__pyx_n_s_name_2;
  PyObject *__pyx_kp_u_neither_contig_nor_region_are_gi;
  PyObject *__pyx_kp_u_o;
  PyObject *__pyx_kp_u_o_2;
  PyObject *__pyx_n_s_object;
  PyObject *__pyx_n_s_offset;
  PyObject *__pyx_n_s_open;
  PyObject *__pyx_n_s_os;
  PyObject *__pyx_n_s_out;
  PyObject *__pyx_n_s_out_stderr;
  PyObject *__pyx_n_s_out_stdout;
  PyObject *__pyx_kp_u_output;
  PyObject *__pyx_kp_u_output_file;
  PyObject *__pyx_n_s_parse_region;
  PyObject *__pyx_n_s_path;
  PyObject *__pyx_n_s_pysam_dispatch;
  PyObject *__pyx_n_s_pysam_dispatch_locals__collect;
  PyObject *__pyx_kp_u_pysam_latin1replace;
  PyObject *__pyx_n_s_pysam_libcutils;
  PyObject *__pyx_kp_s_pysam_libcutils_pyx;
  PyObject *__pyx_n_s_qualities;
  PyObject *__pyx_n_s_qualities_to_qualitystring;
  PyObject *__pyx_n_u_qualities_to_qualitystring;
  PyObject *__pyx_n_s_qualitystring_to_array;
  PyObject *__pyx_n_u_qualitystring_to_array;
  PyObject *__pyx_n_u_r;
  PyObject *__pyx_n_u_rb;
  PyObject *__pyx_n_s_re;
  PyObject *__pyx_n_s_read;
  PyObject *__pyx_n_s_reference;
  PyObject *__pyx_n_s_region;
  PyObject *__pyx_n_s_register_error;
  PyObject *__pyx_n_s_remove;
  PyObject *__pyx_n_s_retval;
  PyObject *__pyx_n_u_roh;
  PyObject *__pyx_n_b_samtools;
  PyObject *__pyx_n_u_samtools;
  PyObject *__pyx_n_s_save_stdout;
  PyObject *__pyx_n_s_set_encoding_error_handler;
  PyObject *__pyx_n_u_set_encoding_error_handler;
  PyObject *__pyx_n_s_skip_next;
  PyObject *__pyx_n_s_spec;
  PyObject *__pyx_n_s_split;
  PyObject *__pyx_n_s_start;
  PyObject *__pyx_kp_u_start_out_of_range_i;
  PyObject *__pyx_n_s_startswith;
  PyObject *__pyx_n_u_stats;
  PyObject *__pyx_n_s_stderr_f;
  PyObject *__pyx_n_s_stderr_h;
  PyObject *__pyx_n_s_stdout_f;
  PyObject *__pyx_n_s_stdout_h;
  PyObject *__pyx_n_s_stdout_option;
  PyObject *__pyx_n_s_stop;
  PyObject *__pyx_kp_u_stop_and_end_should_not_both_be;
  PyObject *__pyx_kp_u_stop_out_of_range_i;
  PyObject *__pyx_n_u_strict;
  PyObject *__pyx_n_s_string;
  PyObject *__pyx_n_s_sys;
  PyObject *__pyx_n_s_tempfile;
  PyObject *__pyx_n_s_test;
  PyObject *__pyx_kp_u_threads;
  PyObject *__pyx_n_s_tobytes;
  PyObject *__pyx_n_s_types;
  PyObject *__pyx_kp_u_utf_8;
  PyObject *__pyx_n_u_view;
  PyObject *__pyx_int_1;
  PyObject *__pyx_int_33;
  PyObject *__pyx_int_neg_1;
  PyObject *__pyx_tuple__2;
  PyObject *__pyx_tuple__3;
  PyObject *__pyx_tuple__4;
  PyObject *__pyx_tuple__5;
  PyObject *__pyx_tuple__6;
  PyObject *__pyx_tuple__9;
  PyObject *__pyx_tuple__12;
  PyObject *__pyx_tuple__16;
  PyObject *__pyx_tuple__18;
  PyObject *__pyx_tuple__19;
  PyObject *__pyx_tuple__22;
  PyObject *__pyx_tuple__25;
  PyObject *__pyx_tuple__27;
  PyObject *__pyx_tuple__29;
  PyObject *__pyx_tuple__30;
  PyObject *__pyx_tuple__32;
  PyObject *__pyx_codeobj__13;
  PyObject *__pyx_codeobj__17;
  PyObject *__pyx_codeobj__20;
  PyObject *__pyx_codeobj__21;
  PyObject *__pyx_codeobj__23;
  PyObject *__pyx_codeobj__24;
  PyObject *__pyx_codeobj__26;
  PyObject *__pyx_codeobj__28;
  PyObject *__pyx_codeobj__31;
} __pyx_mstate;

#if CYTHON_USE_MODULE_STATE
#ifdef __cplusplus
namespace {
  extern struct PyModuleDef __pyx_moduledef;
} /* anonymous namespace */
#else
static struct PyModuleDef __pyx_moduledef;
#endif

#define __pyx_mstate(o) ((__pyx_mstate *)__Pyx_PyModule_GetState(o))

#define __pyx_mstate_global (__pyx_mstate(PyState_FindModule(&__pyx_moduledef)))

#define __pyx_m (PyState_FindModule(&__pyx_moduledef))
#else
static __pyx_mstate __pyx_mstate_global_static =
#ifdef __cplusplus
    {};
#else
    {0};
#endif
static __pyx_mstate *__pyx_mstate_global = &__pyx_mstate_global_static;
#endif
/* #### Code section: module_state_clear ### */
#if CYTHON_USE_MODULE_STATE
static int __pyx_m_clear(PyObject *m) {
  __pyx_mstate *clear_module_state = __pyx_mstate(m);
  if (!clear_module_state) return 0;
  Py_CLEAR(clear_module_state->__pyx_d);
  Py_CLEAR(clear_module_state->__pyx_b);
  Py_CLEAR(clear_module_state->__pyx_cython_runtime);
  Py_CLEAR(clear_module_state->__pyx_empty_tuple);
  Py_CLEAR(clear_module_state->__pyx_empty_bytes);
  Py_CLEAR(clear_module_state->__pyx_empty_unicode);
  #ifdef __Pyx_CyFunction_USED
  Py_CLEAR(clear_module_state->__pyx_CyFunctionType);
  #endif
  #ifdef __Pyx_FusedFunction_USED
  Py_CLEAR(clear_module_state->__pyx_FusedFunctionType);
  #endif
  Py_CLEAR(clear_module_state->__pyx_ptype_7cpython_4type_type);
  Py_CLEAR(clear_module_state->__pyx_ptype_7cpython_4bool_bool);
  Py_CLEAR(clear_module_state->__pyx_ptype_7cpython_7complex_complex);
  Py_CLEAR(clear_module_state->__pyx_ptype_7cpython_5array_array);
  Py_CLEAR(clear_module_state->__pyx_kp_u_);
  Py_CLEAR(clear_module_state->__pyx_n_s_ARGUMENTS);
  Py_CLEAR(clear_module_state->__pyx_kp_u_Argument_must_be_string_bytes_or);
  Py_CLEAR(clear_module_state->__pyx_n_u_B);
  Py_CLEAR(clear_module_state->__pyx_n_s_IOError);
  Py_CLEAR(clear_module_state->__pyx_n_s_MAP_STDOUT_OPTIONS);
  Py_CLEAR(clear_module_state->__pyx_n_s_MemoryError);
  Py_CLEAR(clear_module_state->__pyx_kp_u_No_such_file_or_directory_s);
  Py_CLEAR(clear_module_state->__pyx_n_s_OverflowError);
  Py_CLEAR(clear_module_state->__pyx_n_s_TypeError);
  Py_CLEAR(clear_module_state->__pyx_n_s_UnicodeDecodeError);
  Py_CLEAR(clear_module_state->__pyx_n_s_ValueError);
  Py_CLEAR(clear_module_state->__pyx_kp_u__10);
  Py_CLEAR(clear_module_state->__pyx_kp_u__11);
  Py_CLEAR(clear_module_state->__pyx_n_s__14);
  Py_CLEAR(clear_module_state->__pyx_kp_u__15);
  Py_CLEAR(clear_module_state->__pyx_n_s__33);
  Py_CLEAR(clear_module_state->__pyx_kp_u__7);
  Py_CLEAR(clear_module_state->__pyx_kp_u__8);
  Py_CLEAR(clear_module_state->__pyx_n_s_a);
  Py_CLEAR(clear_module_state->__pyx_n_s_all);
  Py_CLEAR(clear_module_state->__pyx_n_s_arg);
  Py_CLEAR(clear_module_state->__pyx_n_s_args);
  Py_CLEAR(clear_module_state->__pyx_n_s_array_to_qualitystring);
  Py_CLEAR(clear_module_state->__pyx_n_u_array_to_qualitystring);
  Py_CLEAR(clear_module_state->__pyx_n_u_ascii);
  Py_CLEAR(clear_module_state->__pyx_n_s_asyncio_coroutines);
  Py_CLEAR(clear_module_state->__pyx_n_b_bcftools);
  Py_CLEAR(clear_module_state->__pyx_n_u_bcftools);
  Py_CLEAR(clear_module_state->__pyx_kp_u_c);
  Py_CLEAR(clear_module_state->__pyx_n_u_calmd);
  Py_CLEAR(clear_module_state->__pyx_n_s_cargs);
  Py_CLEAR(clear_module_state->__pyx_n_s_catch_stdout);
  Py_CLEAR(clear_module_state->__pyx_n_s_chr);
  Py_CLEAR(clear_module_state->__pyx_n_s_class_getitem);
  Py_CLEAR(clear_module_state->__pyx_n_s_cline_in_traceback);
  Py_CLEAR(clear_module_state->__pyx_n_s_close);
  Py_CLEAR(clear_module_state->__pyx_n_s_codecs);
  Py_CLEAR(clear_module_state->__pyx_n_s_collect);
  Py_CLEAR(clear_module_state->__pyx_n_s_collection);
  Py_CLEAR(clear_module_state->__pyx_n_s_contextlib);
  Py_CLEAR(clear_module_state->__pyx_n_s_contextmanager);
  Py_CLEAR(clear_module_state->__pyx_n_s_contig);
  Py_CLEAR(clear_module_state->__pyx_kp_u_contig_and_reference_should_not);
  Py_CLEAR(clear_module_state->__pyx_kp_u_contig_reference_and_region_shou);
  Py_CLEAR(clear_module_state->__pyx_n_s_decode);
  Py_CLEAR(clear_module_state->__pyx_n_u_depad);
  Py_CLEAR(clear_module_state->__pyx_n_s_encode);
  Py_CLEAR(clear_module_state->__pyx_n_s_end);
  Py_CLEAR(clear_module_state->__pyx_n_s_enter);
  Py_CLEAR(clear_module_state->__pyx_kp_u_error_while_opening_for_writing);
  Py_CLEAR(clear_module_state->__pyx_n_s_exception);
  Py_CLEAR(clear_module_state->__pyx_n_s_exists);
  Py_CLEAR(clear_module_state->__pyx_n_s_exit);
  Py_CLEAR(clear_module_state->__pyx_n_s_extend);
  Py_CLEAR(clear_module_state->__pyx_n_s_extra_args);
  Py_CLEAR(clear_module_state->__pyx_n_s_fn);
  Py_CLEAR(clear_module_state->__pyx_n_s_format);
  Py_CLEAR(clear_module_state->__pyx_n_s_fsencode);
  Py_CLEAR(clear_module_state->__pyx_n_s_get_encoding_error_handler);
  Py_CLEAR(clear_module_state->__pyx_n_u_get_encoding_error_handler);
  Py_CLEAR(clear_module_state->__pyx_n_s_getdefaultencoding);
  Py_CLEAR(clear_module_state->__pyx_n_s_getfilesystemencoding);
  Py_CLEAR(clear_module_state->__pyx_n_s_i);
  Py_CLEAR(clear_module_state->__pyx_n_s_import);
  Py_CLEAR(clear_module_state->__pyx_n_b_index);
  Py_CLEAR(clear_module_state->__pyx_n_u_index);
  Py_CLEAR(clear_module_state->__pyx_n_s_inf);
  Py_CLEAR(clear_module_state->__pyx_n_s_initializing);
  Py_CLEAR(clear_module_state->__pyx_n_s_input_str);
  Py_CLEAR(clear_module_state->__pyx_kp_u_invalid_coordinates_start_i_stop);
  Py_CLEAR(clear_module_state->__pyx_n_s_io);
  Py_CLEAR(clear_module_state->__pyx_n_s_is_coroutine);
  Py_CLEAR(clear_module_state->__pyx_n_s_is_usage);
  Py_CLEAR(clear_module_state->__pyx_n_s_l);
  Py_CLEAR(clear_module_state->__pyx_n_s_latin1_replace);
  Py_CLEAR(clear_module_state->__pyx_kp_u_m);
  Py_CLEAR(clear_module_state->__pyx_n_s_main);
  Py_CLEAR(clear_module_state->__pyx_n_s_method);
  Py_CLEAR(clear_module_state->__pyx_kp_u_min_shift);
  Py_CLEAR(clear_module_state->__pyx_n_s_mkstemp);
  Py_CLEAR(clear_module_state->__pyx_n_u_mpileup);
  Py_CLEAR(clear_module_state->__pyx_n_s_n);
  Py_CLEAR(clear_module_state->__pyx_n_s_name);
  Py_CLEAR(clear_module_state->__pyx_n_s_name_2);
  Py_CLEAR(clear_module_state->__pyx_kp_u_neither_contig_nor_region_are_gi);
  Py_CLEAR(clear_module_state->__pyx_kp_u_o);
  Py_CLEAR(clear_module_state->__pyx_kp_u_o_2);
  Py_CLEAR(clear_module_state->__pyx_n_s_object);
  Py_CLEAR(clear_module_state->__pyx_n_s_offset);
  Py_CLEAR(clear_module_state->__pyx_n_s_open);
  Py_CLEAR(clear_module_state->__pyx_n_s_os);
  Py_CLEAR(clear_module_state->__pyx_n_s_out);
  Py_CLEAR(clear_module_state->__pyx_n_s_out_stderr);
  Py_CLEAR(clear_module_state->__pyx_n_s_out_stdout);
  Py_CLEAR(clear_module_state->__pyx_kp_u_output);
  Py_CLEAR(clear_module_state->__pyx_kp_u_output_file);
  Py_CLEAR(clear_module_state->__pyx_n_s_parse_region);
  Py_CLEAR(clear_module_state->__pyx_n_s_path);
  Py_CLEAR(clear_module_state->__pyx_n_s_pysam_dispatch);
  Py_CLEAR(clear_module_state->__pyx_n_s_pysam_dispatch_locals__collect);
  Py_CLEAR(clear_module_state->__pyx_kp_u_pysam_latin1replace);
  Py_CLEAR(clear_module_state->__pyx_n_s_pysam_libcutils);
  Py_CLEAR(clear_module_state->__pyx_kp_s_pysam_libcutils_pyx);
  Py_CLEAR(clear_module_state->__pyx_n_s_qualities);
  Py_CLEAR(clear_module_state->__pyx_n_s_qualities_to_qualitystring);
  Py_CLEAR(clear_module_state->__pyx_n_u_qualities_to_qualitystring);
  Py_CLEAR(clear_module_state->__pyx_n_s_qualitystring_to_array);
  Py_CLEAR(clear_module_state->__pyx_n_u_qualitystring_to_array);
  Py_CLEAR(clear_module_state->__pyx_n_u_r);
  Py_CLEAR(clear_module_state->__pyx_n_u_rb);
  Py_CLEAR(clear_module_state->__pyx_n_s_re);
  Py_CLEAR(clear_module_state->__pyx_n_s_read);
  Py_CLEAR(clear_module_state->__pyx_n_s_reference);
  Py_CLEAR(clear_module_state->__pyx_n_s_region);
  Py_CLEAR(clear_module_state->__pyx_n_s_register_error);
  Py_CLEAR(clear_module_state->__pyx_n_s_remove);
  Py_CLEAR(clear_module_state->__pyx_n_s_retval);
  Py_CLEAR(clear_module_state->__pyx_n_u_roh);
  Py_CLEAR(clear_module_state->__pyx_n_b_samtools);
  Py_CLEAR(clear_module_state->__pyx_n_u_samtools);
  Py_CLEAR(clear_module_state->__pyx_n_s_save_stdout);
  Py_CLEAR(clear_module_state->__pyx_n_s_set_encoding_error_handler);
  Py_CLEAR(clear_module_state->__pyx_n_u_set_encoding_error_handler);
  Py_CLEAR(clear_module_state->__pyx_n_s_skip_next);
  Py_CLEAR(clear_module_state->__pyx_n_s_spec);
  Py_CLEAR(clear_module_state->__pyx_n_s_split);
  Py_CLEAR(clear_module_state->__pyx_n_s_start);
  Py_CLEAR(clear_module_state->__pyx_kp_u_start_out_of_range_i);
  Py_CLEAR(clear_module_state->__pyx_n_s_startswith);
  Py_CLEAR(clear_module_state->__pyx_n_u_stats);
  Py_CLEAR(clear_module_state->__pyx_n_s_stderr_f);
  Py_CLEAR(clear_module_state->__pyx_n_s_stderr_h);
  Py_CLEAR(clear_module_state->__pyx_n_s_stdout_f);
  Py_CLEAR(clear_module_state->__pyx_n_s_stdout_h);
  Py_CLEAR(clear_module_state->__pyx_n_s_stdout_option);
  Py_CLEAR(clear_module_state->__pyx_n_s_stop);
  Py_CLEAR(clear_module_state->__pyx_kp_u_stop_and_end_should_not_both_be);
  Py_CLEAR(clear_module_state->__pyx_kp_u_stop_out_of_range_i);
  Py_CLEAR(clear_module_state->__pyx_n_u_strict);
  Py_CLEAR(clear_module_state->__pyx_n_s_string);
  Py_CLEAR(clear_module_state->__pyx_n_s_sys);
  Py_CLEAR(clear_module_state->__pyx_n_s_tempfile);
  Py_CLEAR(clear_module_state->__pyx_n_s_test);
  Py_CLEAR(clear_module_state->__pyx_kp_u_threads);
  Py_CLEAR(clear_module_state->__pyx_n_s_tobytes);
  Py_CLEAR(clear_module_state->__pyx_n_s_types);
  Py_CLEAR(clear_module_state->__pyx_kp_u_utf_8);
  Py_CLEAR(clear_module_state->__pyx_n_u_view);
  Py_CLEAR(clear_module_state->__pyx_int_1);
  Py_CLEAR(clear_module_state->__pyx_int_33);
  Py_CLEAR(clear_module_state->__pyx_int_neg_1);
  Py_CLEAR(clear_module_state->__pyx_tuple__2);
  Py_CLEAR(clear_module_state->__pyx_tuple__3);
  Py_CLEAR(clear_module_state->__pyx_tuple__4);
  Py_CLEAR(clear_module_state->__pyx_tuple__5);
  Py_CLEAR(clear_module_state->__pyx_tuple__6);
  Py_CLEAR(clear_module_state->__pyx_tuple__9);
  Py_CLEAR(clear_module_state->__pyx_tuple__12);
  Py_CLEAR(clear_module_state->__pyx_tuple__16);
  Py_CLEAR(clear_module_state->__pyx_tuple__18);
  Py_CLEAR(clear_module_state->__pyx_tuple__19);
  Py_CLEAR(clear_module_state->__pyx_tuple__22);
  Py_CLEAR(clear_module_state->__pyx_tuple__25);
  Py_CLEAR(clear_module_state->__pyx_tuple__27);
  Py_CLEAR(clear_module_state->__pyx_tuple__29);
  Py_CLEAR(clear_module_state->__pyx_tuple__30);
  Py_CLEAR(clear_module_state->__pyx_tuple__32);
  Py_CLEAR(clear_module_state->__pyx_codeobj__13);
  Py_CLEAR(clear_module_state->__pyx_codeobj__17);
  Py_CLEAR(clear_module_state->__pyx_codeobj__20);
  Py_CLEAR(clear_module_state->__pyx_codeobj__21);
  Py_CLEAR(clear_module_state->__pyx_codeobj__23);
  Py_CLEAR(clear_module_state->__pyx_codeobj__24);
  Py_CLEAR(clear_module_state->__pyx_codeobj__26);
  Py_CLEAR(clear_module_state->__pyx_codeobj__28);
  Py_CLEAR(clear_module_state->__pyx_codeobj__31);
  return 0;
}
#endif
/* #### Code section: module_state_traverse ### */
#if CYTHON_USE_MODULE_STATE
static int __pyx_m_traverse(PyObject *m, visitproc visit, void *arg) {
  __pyx_mstate *traverse_module_state = __pyx_mstate(m);
  if (!traverse_module_state) return 0;
  Py_VISIT(traverse_module_state->__pyx_d);
  Py_VISIT(traverse_module_state->__pyx_b);
  Py_VISIT(traverse_module_state->__pyx_cython_runtime);
  Py_VISIT(traverse_module_state->__pyx_empty_tuple);
  Py_VISIT(traverse_module_state->__pyx_empty_bytes);
  Py_VISIT(traverse_module_state->__pyx_empty_unicode);
  #ifdef __Pyx_CyFunction_USED
  Py_VISIT(traverse_module_state->__pyx_CyFunctionType);
  #endif
  #ifdef __Pyx_FusedFunction_USED
  Py_VISIT(traverse_module_state->__pyx_FusedFunctionType);
  #endif
  Py_VISIT(traverse_module_state->__pyx_ptype_7cpython_4type_type);
  Py_VISIT(traverse_module_state->__pyx_ptype_7cpython_4bool_bool);
  Py_VISIT(traverse_module_state->__pyx_ptype_7cpython_7complex_complex);
  Py_VISIT(traverse_module_state->__pyx_ptype_7cpython_5array_array);
  Py_VISIT(traverse_module_state->__pyx_kp_u_);
  Py_VISIT(traverse_module_state->__pyx_n_s_ARGUMENTS);
  Py_VISIT(traverse_module_state->__pyx_kp_u_Argument_must_be_string_bytes_or);
  Py_VISIT(traverse_module_state->__pyx_n_u_B);
  Py_VISIT(traverse_module_state->__pyx_n_s_IOError);
  Py_VISIT(traverse_module_state->__pyx_n_s_MAP_STDOUT_OPTIONS);
  Py_VISIT(traverse_module_state->__pyx_n_s_MemoryError);
  Py_VISIT(traverse_module_state->__pyx_kp_u_No_such_file_or_directory_s);
  Py_VISIT(traverse_module_state->__pyx_n_s_OverflowError);
  Py_VISIT(traverse_module_state->__pyx_n_s_TypeError);
  Py_VISIT(traverse_module_state->__pyx_n_s_UnicodeDecodeError);
  Py_VISIT(traverse_module_state->__pyx_n_s_ValueError);
  Py_VISIT(traverse_module_state->__pyx_kp_u__10);
  Py_VISIT(traverse_module_state->__pyx_kp_u__11);
  Py_VISIT(traverse_module_state->__pyx_n_s__14);
  Py_VISIT(traverse_module_state->__pyx_kp_u__15);
  Py_VISIT(traverse_module_state->__pyx_n_s__33);
  Py_VISIT(traverse_module_state->__pyx_kp_u__7);
  Py_VISIT(traverse_module_state->__pyx_kp_u__8);
  Py_VISIT(traverse_module_state->__pyx_n_s_a);
  Py_VISIT(traverse_module_state->__pyx_n_s_all);
  Py_VISIT(traverse_module_state->__pyx_n_s_arg);
  Py_VISIT(traverse_module_state->__pyx_n_s_args);
  Py_VISIT(traverse_module_state->__pyx_n_s_array_to_qualitystring);
  Py_VISIT(traverse_module_state->__pyx_n_u_array_to_qualitystring);
  Py_VISIT(traverse_module_state->__pyx_n_u_ascii);
  Py_VISIT(traverse_module_state->__pyx_n_s_asyncio_coroutines);
  Py_VISIT(traverse_module_state->__pyx_n_b_bcftools);
  Py_VISIT(traverse_module_state->__pyx_n_u_bcftools);
  Py_VISIT(traverse_module_state->__pyx_kp_u_c);
  Py_VISIT(traverse_module_state->__pyx_n_u_calmd);
  Py_VISIT(traverse_module_state->__pyx_n_s_cargs);
  Py_VISIT(traverse_module_state->__pyx_n_s_catch_stdout);
  Py_VISIT(traverse_module_state->__pyx_n_s_chr);
  Py_VISIT(traverse_module_state->__pyx_n_s_class_getitem);
  Py_VISIT(traverse_module_state->__pyx_n_s_cline_in_traceback);
  Py_VISIT(traverse_module_state->__pyx_n_s_close);
  Py_VISIT(traverse_module_state->__pyx_n_s_codecs);
  Py_VISIT(traverse_module_state->__pyx_n_s_collect);
  Py_VISIT(traverse_module_state->__pyx_n_s_collection);
  Py_VISIT(traverse_module_state->__pyx_n_s_contextlib);
  Py_VISIT(traverse_module_state->__pyx_n_s_contextmanager);
  Py_VISIT(traverse_module_state->__pyx_n_s_contig);
  Py_VISIT(traverse_module_state->__pyx_kp_u_contig_and_reference_should_not);
  Py_VISIT(traverse_module_state->__pyx_kp_u_contig_reference_and_region_shou);
  Py_VISIT(traverse_module_state->__pyx_n_s_decode);
  Py_VISIT(traverse_module_state->__pyx_n_u_depad);
  Py_VISIT(traverse_module_state->__pyx_n_s_encode);
  Py_VISIT(traverse_module_state->__pyx_n_s_end);
  Py_VISIT(traverse_module_state->__pyx_n_s_enter);
  Py_VISIT(traverse_module_state->__pyx_kp_u_error_while_opening_for_writing);
  Py_VISIT(traverse_module_state->__pyx_n_s_exception);
  Py_VISIT(traverse_module_state->__pyx_n_s_exists);
  Py_VISIT(traverse_module_state->__pyx_n_s_exit);
  Py_VISIT(traverse_module_state->__pyx_n_s_extend);
  Py_VISIT(traverse_module_state->__pyx_n_s_extra_args);
  Py_VISIT(traverse_module_state->__pyx_n_s_fn);
  Py_VISIT(traverse_module_state->__pyx_n_s_format);
  Py_VISIT(traverse_module_state->__pyx_n_s_fsencode);
  Py_VISIT(traverse_module_state->__pyx_n_s_get_encoding_error_handler);
  Py_VISIT(traverse_module_state->__pyx_n_u_get_encoding_error_handler);
  Py_VISIT(traverse_module_state->__pyx_n_s_getdefaultencoding);
  Py_VISIT(traverse_module_state->__pyx_n_s_getfilesystemencoding);
  Py_VISIT(traverse_module_state->__pyx_n_s_i);
  Py_VISIT(traverse_module_state->__pyx_n_s_import);
  Py_VISIT(traverse_module_state->__pyx_n_b_index);
  Py_VISIT(traverse_module_state->__pyx_n_u_index);
  Py_VISIT(traverse_module_state->__pyx_n_s_inf);
  Py_VISIT(traverse_module_state->__pyx_n_s_initializing);
  Py_VISIT(traverse_module_state->__pyx_n_s_input_str);
  Py_VISIT(traverse_module_state->__pyx_kp_u_invalid_coordinates_start_i_stop);
  Py_VISIT(traverse_module_state->__pyx_n_s_io);
  Py_VISIT(traverse_module_state->__pyx_n_s_is_coroutine);
  Py_VISIT(traverse_module_state->__pyx_n_s_is_usage);
  Py_VISIT(traverse_module_state->__pyx_n_s_l);
  Py_VISIT(traverse_module_state->__pyx_n_s_latin1_replace);
  Py_VISIT(traverse_module_state->__pyx_kp_u_m);
  Py_VISIT(traverse_module_state->__pyx_n_s_main);
  Py_VISIT(traverse_module_state->__pyx_n_s_method);
  Py_VISIT(traverse_module_state->__pyx_kp_u_min_shift);
  Py_VISIT(traverse_module_state->__pyx_n_s_mkstemp);
  Py_VISIT(traverse_module_state->__pyx_n_u_mpileup);
  Py_VISIT(traverse_module_state->__pyx_n_s_n);
  Py_VISIT(traverse_module_state->__pyx_n_s_name);
  Py_VISIT(traverse_module_state->__pyx_n_s_name_2);
  Py_VISIT(traverse_module_state->__pyx_kp_u_neither_contig_nor_region_are_gi);
  Py_VISIT(traverse_module_state->__pyx_kp_u_o);
  Py_VISIT(traverse_module_state->__pyx_kp_u_o_2);
  Py_VISIT(traverse_module_state->__pyx_n_s_object);
  Py_VISIT(traverse_module_state->__pyx_n_s_offset);
  Py_VISIT(traverse_module_state->__pyx_n_s_open);
  Py_VISIT(traverse_module_state->__pyx_n_s_os);
  Py_VISIT(traverse_module_state->__pyx_n_s_out);
  Py_VISIT(traverse_module_state->__pyx_n_s_out_stderr);
  Py_VISIT(traverse_module_state->__pyx_n_s_out_stdout);
  Py_VISIT(traverse_module_state->__pyx_kp_u_output);
  Py_VISIT(traverse_module_state->__pyx_kp_u_output_file);
  Py_VISIT(traverse_module_state->__pyx_n_s_parse_region);
  Py_VISIT(traverse_module_state->__pyx_n_s_path);
  Py_VISIT(traverse_module_state->__pyx_n_s_pysam_dispatch);
  Py_VISIT(traverse_module_state->__pyx_n_s_pysam_dispatch_locals__collect);
  Py_VISIT(traverse_module_state->__pyx_kp_u_pysam_latin1replace);
  Py_VISIT(traverse_module_state->__pyx_n_s_pysam_libcutils);
  Py_VISIT(traverse_module_state->__pyx_kp_s_pysam_libcutils_pyx);
  Py_VISIT(traverse_module_state->__pyx_n_s_qualities);
  Py_VISIT(traverse_module_state->__pyx_n_s_qualities_to_qualitystring);
  Py_VISIT(traverse_module_state->__pyx_n_u_qualities_to_qualitystring);
  Py_VISIT(traverse_module_state->__pyx_n_s_qualitystring_to_array);
  Py_VISIT(traverse_module_state->__pyx_n_u_qualitystring_to_array);
  Py_VISIT(traverse_module_state->__pyx_n_u_r);
  Py_VISIT(traverse_module_state->__pyx_n_u_rb);
  Py_VISIT(traverse_module_state->__pyx_n_s_re);
  Py_VISIT(traverse_module_state->__pyx_n_s_read);
  Py_VISIT(traverse_module_state->__pyx_n_s_reference);
  Py_VISIT(traverse_module_state->__pyx_n_s_region);
  Py_VISIT(traverse_module_state->__pyx_n_s_register_error);
  Py_VISIT(traverse_module_state->__pyx_n_s_remove);
  Py_VISIT(traverse_module_state->__pyx_n_s_retval);
  Py_VISIT(traverse_module_state->__pyx_n_u_roh);
  Py_VISIT(traverse_module_state->__pyx_n_b_samtools);
  Py_VISIT(traverse_module_state->__pyx_n_u_samtools);
  Py_VISIT(traverse_module_state->__pyx_n_s_save_stdout);
  Py_VISIT(traverse_module_state->__pyx_n_s_set_encoding_error_handler);
  Py_VISIT(traverse_module_state->__pyx_n_u_set_encoding_error_handler);
  Py_VISIT(traverse_module_state->__pyx_n_s_skip_next);
  Py_VISIT(traverse_module_state->__pyx_n_s_spec);
  Py_VISIT(traverse_module_state->__pyx_n_s_split);
  Py_VISIT(traverse_module_state->__pyx_n_s_start);
  Py_VISIT(traverse_module_state->__pyx_kp_u_start_out_of_range_i);
  Py_VISIT(traverse_module_state->__pyx_n_s_startswith);
  Py_VISIT(traverse_module_state->__pyx_n_u_stats);
  Py_VISIT(traverse_module_state->__pyx_n_s_stderr_f);
  Py_VISIT(traverse_module_state->__pyx_n_s_stderr_h);
  Py_VISIT(traverse_module_state->__pyx_n_s_stdout_f);
  Py_VISIT(traverse_module_state->__pyx_n_s_stdout_h);
  Py_VISIT(traverse_module_state->__pyx_n_s_stdout_option);
  Py_VISIT(traverse_module_state->__pyx_n_s_stop);
  Py_VISIT(traverse_module_state->__pyx_kp_u_stop_and_end_should_not_both_be);
  Py_VISIT(traverse_module_state->__pyx_kp_u_stop_out_of_range_i);
  Py_VISIT(traverse_module_state->__pyx_n_u_strict);
  Py_VISIT(traverse_module_state->__pyx_n_s_string);
  Py_VISIT(traverse_module_state->__pyx_n_s_sys);
  Py_VISIT(traverse_module_state->__pyx_n_s_tempfile);
  Py_VISIT(traverse_module_state->__pyx_n_s_test);
  Py_VISIT(traverse_module_state->__pyx_kp_u_threads);
  Py_VISIT(traverse_module_state->__pyx_n_s_tobytes);
  Py_VISIT(traverse_module_state->__pyx_n_s_types);
  Py_VISIT(traverse_module_state->__pyx_kp_u_utf_8);
  Py_VISIT(traverse_module_state->__pyx_n_u_view);
  Py_VISIT(traverse_module_state->__pyx_int_1);
  Py_VISIT(traverse_module_state->__pyx_int_33);
  Py_VISIT(traverse_module_state->__pyx_int_neg_1);
  Py_VISIT(traverse_module_state->__pyx_tuple__2);
  Py_VISIT(traverse_module_state->__pyx_tuple__3);
  Py_VISIT(traverse_module_state->__pyx_tuple__4);
  Py_VISIT(traverse_module_state->__pyx_tuple__5);
  Py_VISIT(traverse_module_state->__pyx_tuple__6);
  Py_VISIT(traverse_module_state->__pyx_tuple__9);
  Py_VISIT(traverse_module_state->__pyx_tuple__12);
  Py_VISIT(traverse_module_state->__pyx_tuple__16);
  Py_VISIT(traverse_module_state->__pyx_tuple__18);
  Py_VISIT(traverse_module_state->__pyx_tuple__19);
  Py_VISIT(traverse_module_state->__pyx_tuple__22);
  Py_VISIT(traverse_module_state->__pyx_tuple__25);
  Py_VISIT(traverse_module_state->__pyx_tuple__27);
  Py_VISIT(traverse_module_state->__pyx_tuple__29);
  Py_VISIT(traverse_module_state->__pyx_tuple__30);
  Py_VISIT(traverse_module_state->__pyx_tuple__32);
  Py_VISIT(traverse_module_state->__pyx_codeobj__13);
  Py_VISIT(traverse_module_state->__pyx_codeobj__17);
  Py_VISIT(traverse_module_state->__pyx_codeobj__20);
  Py_VISIT(traverse_module_state->__pyx_codeobj__21);
  Py_VISIT(traverse_module_state->__pyx_codeobj__23);
  Py_VISIT(traverse_module_state->__pyx_codeobj__24);
  Py_VISIT(traverse_module_state->__pyx_codeobj__26);
  Py_VISIT(traverse_module_state->__pyx_codeobj__28);
  Py_VISIT(traverse_module_state->__pyx_codeobj__31);
  return 0;
}
#endif
/* #### Code section: module_state_defines ### */
#define __pyx_d __pyx_mstate_global->__pyx_d
#define __pyx_b __pyx_mstate_global->__pyx_b
#define __pyx_cython_runtime __pyx_mstate_global->__pyx_cython_runtime
#define __pyx_empty_tuple __pyx_mstate_global->__pyx_empty_tuple
#define __pyx_empty_bytes __pyx_mstate_global->__pyx_empty_bytes
#define __pyx_empty_unicode __pyx_mstate_global->__pyx_empty_unicode
#ifdef __Pyx_CyFunction_USED
#define __pyx_CyFunctionType __pyx_mstate_global->__pyx_CyFunctionType
#endif
#ifdef __Pyx_FusedFunction_USED
#define __pyx_FusedFunctionType __pyx_mstate_global->__pyx_FusedFunctionType
#endif
#ifdef __Pyx_Generator_USED
#define __pyx_GeneratorType __pyx_mstate_global->__pyx_GeneratorType
#endif
#ifdef __Pyx_IterableCoroutine_USED
#define __pyx_IterableCoroutineType __pyx_mstate_global->__pyx_IterableCoroutineType
#endif
#ifdef __Pyx_Coroutine_USED
#define __pyx_CoroutineAwaitType __pyx_mstate_global->__pyx_CoroutineAwaitType
#endif
#ifdef __Pyx_Coroutine_USED
#define __pyx_CoroutineType __pyx_mstate_global->__pyx_CoroutineType
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#define __pyx_ptype_7cpython_4type_type __pyx_mstate_global->__pyx_ptype_7cpython_4type_type
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#define __pyx_ptype_7cpython_4bool_bool __pyx_mstate_global->__pyx_ptype_7cpython_4bool_bool
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#define __pyx_ptype_7cpython_7complex_complex __pyx_mstate_global->__pyx_ptype_7cpython_7complex_complex
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#define __pyx_ptype_7cpython_5array_array __pyx_mstate_global->__pyx_ptype_7cpython_5array_array
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#if CYTHON_USE_MODULE_STATE
#endif
#define __pyx_kp_u_ __pyx_mstate_global->__pyx_kp_u_
#define __pyx_n_s_ARGUMENTS __pyx_mstate_global->__pyx_n_s_ARGUMENTS
#define __pyx_kp_u_Argument_must_be_string_bytes_or __pyx_mstate_global->__pyx_kp_u_Argument_must_be_string_bytes_or
#define __pyx_n_u_B __pyx_mstate_global->__pyx_n_u_B
#define __pyx_n_s_IOError __pyx_mstate_global->__pyx_n_s_IOError
#define __pyx_n_s_MAP_STDOUT_OPTIONS __pyx_mstate_global->__pyx_n_s_MAP_STDOUT_OPTIONS
#define __pyx_n_s_MemoryError __pyx_mstate_global->__pyx_n_s_MemoryError
#define __pyx_kp_u_No_such_file_or_directory_s __pyx_mstate_global->__pyx_kp_u_No_such_file_or_directory_s
#define __pyx_n_s_OverflowError __pyx_mstate_global->__pyx_n_s_OverflowError
#define __pyx_n_s_TypeError __pyx_mstate_global->__pyx_n_s_TypeError
#define __pyx_n_s_UnicodeDecodeError __pyx_mstate_global->__pyx_n_s_UnicodeDecodeError
#define __pyx_n_s_ValueError __pyx_mstate_global->__pyx_n_s_ValueError
#define __pyx_kp_u__10 __pyx_mstate_global->__pyx_kp_u__10
#define __pyx_kp_u__11 __pyx_mstate_global->__pyx_kp_u__11
#define __pyx_n_s__14 __pyx_mstate_global->__pyx_n_s__14
#define __pyx_kp_u__15 __pyx_mstate_global->__pyx_kp_u__15
#define __pyx_n_s__33 __pyx_mstate_global->__pyx_n_s__33
#define __pyx_kp_u__7 __pyx_mstate_global->__pyx_kp_u__7
#define __pyx_kp_u__8 __pyx_mstate_global->__pyx_kp_u__8
#define __pyx_n_s_a __pyx_mstate_global->__pyx_n_s_a
#define __pyx_n_s_all __pyx_mstate_global->__pyx_n_s_all
#define __pyx_n_s_arg __pyx_mstate_global->__pyx_n_s_arg
#define __pyx_n_s_args __pyx_mstate_global->__pyx_n_s_args
#define __pyx_n_s_array_to_qualitystring __pyx_mstate_global->__pyx_n_s_array_to_qualitystring
#define __pyx_n_u_array_to_qualitystring __pyx_mstate_global->__pyx_n_u_array_to_qualitystring
#define __pyx_n_u_ascii __pyx_mstate_global->__pyx_n_u_ascii
#define __pyx_n_s_asyncio_coroutines __pyx_mstate_global->__pyx_n_s_asyncio_coroutines
#define __pyx_n_b_bcftools __pyx_mstate_global->__pyx_n_b_bcftools
#define __pyx_n_u_bcftools __pyx_mstate_global->__pyx_n_u_bcftools
#define __pyx_kp_u_c __pyx_mstate_global->__pyx_kp_u_c
#define __pyx_n_u_calmd __pyx_mstate_global->__pyx_n_u_calmd
#define __pyx_n_s_cargs __pyx_mstate_global->__pyx_n_s_cargs
#define __pyx_n_s_catch_stdout __pyx_mstate_global->__pyx_n_s_catch_stdout
#define __pyx_n_s_chr __pyx_mstate_global->__pyx_n_s_chr
#define __pyx_n_s_class_getitem __pyx_mstate_global->__pyx_n_s_class_getitem
#define __pyx_n_s_cline_in_traceback __pyx_mstate_global->__pyx_n_s_cline_in_traceback
#define __pyx_n_s_close __pyx_mstate_global->__pyx_n_s_close
#define __pyx_n_s_codecs __pyx_mstate_global->__pyx_n_s_codecs
#define __pyx_n_s_collect __pyx_mstate_global->__pyx_n_s_collect
#define __pyx_n_s_collection __pyx_mstate_global->__pyx_n_s_collection
#define __pyx_n_s_contextlib __pyx_mstate_global->__pyx_n_s_contextlib
#define __pyx_n_s_contextmanager __pyx_mstate_global->__pyx_n_s_contextmanager
#define __pyx_n_s_contig __pyx_mstate_global->__pyx_n_s_contig
#define __pyx_kp_u_contig_and_reference_should_not __pyx_mstate_global->__pyx_kp_u_contig_and_reference_should_not
#define __pyx_kp_u_contig_reference_and_region_shou __pyx_mstate_global->__pyx_kp_u_contig_reference_and_region_shou
#define __pyx_n_s_decode __pyx_mstate_global->__pyx_n_s_decode
#define __pyx_n_u_depad __pyx_mstate_global->__pyx_n_u_depad
#define __pyx_n_s_encode __pyx_mstate_global->__pyx_n_s_encode
#define __pyx_n_s_end __pyx_mstate_global->__pyx_n_s_end
#define __pyx_n_s_enter __pyx_mstate_global->__pyx_n_s_enter
#define __pyx_kp_u_error_while_opening_for_writing __pyx_mstate_global->__pyx_kp_u_error_while_opening_for_writing
#define __pyx_n_s_exception __pyx_mstate_global->__pyx_n_s_exception
#define __pyx_n_s_exists __pyx_mstate_global->__pyx_n_s_exists
#define __pyx_n_s_exit __pyx_mstate_global->__pyx_n_s_exit
#define __pyx_n_s_extend __pyx_mstate_global->__pyx_n_s_extend
#define __pyx_n_s_extra_args __pyx_mstate_global->__pyx_n_s_extra_args
#define __pyx_n_s_fn __pyx_mstate_global->__pyx_n_s_fn
#define __pyx_n_s_format __pyx_mstate_global->__pyx_n_s_format
#define __pyx_n_s_fsencode __pyx_mstate_global->__pyx_n_s_fsencode
#define __pyx_n_s_get_encoding_error_handler __pyx_mstate_global->__pyx_n_s_get_encoding_error_handler
#define __pyx_n_u_get_encoding_error_handler __pyx_mstate_global->__pyx_n_u_get_encoding_error_handler
#define __pyx_n_s_getdefaultencoding __pyx_mstate_global->__pyx_n_s_getdefaultencoding
#define __pyx_n_s_getfilesystemencoding __pyx_mstate_global->__pyx_n_s_getfilesystemencoding
#define __pyx_n_s_i __pyx_mstate_global->__pyx_n_s_i
#define __pyx_n_s_import __pyx_mstate_global->__pyx_n_s_import
#define __pyx_n_b_index __pyx_mstate_global->__pyx_n_b_index
#define __pyx_n_u_index __pyx_mstate_global->__pyx_n_u_index
#define __pyx_n_s_inf __pyx_mstate_global->__pyx_n_s_inf
#define __pyx_n_s_initializing __pyx_mstate_global->__pyx_n_s_initializing
#define __pyx_n_s_input_str __pyx_mstate_global->__pyx_n_s_input_str
#define __pyx_kp_u_invalid_coordinates_start_i_stop __pyx_mstate_global->__pyx_kp_u_invalid_coordinates_start_i_stop
#define __pyx_n_s_io __pyx_mstate_global->__pyx_n_s_io
#define __pyx_n_s_is_coroutine __pyx_mstate_global->__pyx_n_s_is_coroutine
#define __pyx_n_s_is_usage __pyx_mstate_global->__pyx_n_s_is_usage
#define __pyx_n_s_l __pyx_mstate_global->__pyx_n_s_l
#define __pyx_n_s_latin1_replace __pyx_mstate_global->__pyx_n_s_latin1_replace
#define __pyx_kp_u_m __pyx_mstate_global->__pyx_kp_u_m
#define __pyx_n_s_main __pyx_mstate_global->__pyx_n_s_main
#define __pyx_n_s_method __pyx_mstate_global->__pyx_n_s_method
#define __pyx_kp_u_min_shift __pyx_mstate_global->__pyx_kp_u_min_shift
#define __pyx_n_s_mkstemp __pyx_mstate_global->__pyx_n_s_mkstemp
#define __pyx_n_u_mpileup __pyx_mstate_global->__pyx_n_u_mpileup
#define __pyx_n_s_n __pyx_mstate_global->__pyx_n_s_n
#define __pyx_n_s_name __pyx_mstate_global->__pyx_n_s_name
#define __pyx_n_s_name_2 __pyx_mstate_global->__pyx_n_s_name_2
#define __pyx_kp_u_neither_contig_nor_region_are_gi __pyx_mstate_global->__pyx_kp_u_neither_contig_nor_region_are_gi
#define __pyx_kp_u_o __pyx_mstate_global->__pyx_kp_u_o
#define __pyx_kp_u_o_2 __pyx_mstate_global->__pyx_kp_u_o_2
#define __pyx_n_s_object __pyx_mstate_global->__pyx_n_s_object
#define __pyx_n_s_offset __pyx_mstate_global->__pyx_n_s_offset
#define __pyx_n_s_open __pyx_mstate_global->__pyx_n_s_open
#define __pyx_n_s_os __pyx_mstate_global->__pyx_n_s_os
#define __pyx_n_s_out __pyx_mstate_global->__pyx_n_s_out
#define __pyx_n_s_out_stderr __pyx_mstate_global->__pyx_n_s_out_stderr
#define __pyx_n_s_out_stdout __pyx_mstate_global->__pyx_n_s_out_stdout
#define __pyx_kp_u_output __pyx_mstate_global->__pyx_kp_u_output
#define __pyx_kp_u_output_file __pyx_mstate_global->__pyx_kp_u_output_file
#define __pyx_n_s_parse_region __pyx_mstate_global->__pyx_n_s_parse_region
#define __pyx_n_s_path __pyx_mstate_global->__pyx_n_s_path
#define __pyx_n_s_pysam_dispatch __pyx_mstate_global->__pyx_n_s_pysam_dispatch
#define __pyx_n_s_pysam_dispatch_locals__collect __pyx_mstate_global->__pyx_n_s_pysam_dispatch_locals__collect
#define __pyx_kp_u_pysam_latin1replace __pyx_mstate_global->__pyx_kp_u_pysam_latin1replace
#define __pyx_n_s_pysam_libcutils __pyx_mstate_global->__pyx_n_s_pysam_libcutils
#define __pyx_kp_s_pysam_libcutils_pyx __pyx_mstate_global->__pyx_kp_s_pysam_libcutils_pyx
#define __pyx_n_s_qualities __pyx_mstate_global->__pyx_n_s_qualities
#define __pyx_n_s_qualities_to_qualitystring __pyx_mstate_global->__pyx_n_s_qualities_to_qualitystring
#define __pyx_n_u_qualities_to_qualitystring __pyx_mstate_global->__pyx_n_u_qualities_to_qualitystring
#define __pyx_n_s_qualitystring_to_array __pyx_mstate_global->__pyx_n_s_qualitystring_to_array
#define __pyx_n_u_qualitystring_to_array __pyx_mstate_global->__pyx_n_u_qualitystring_to_array
#define __pyx_n_u_r __pyx_mstate_global->__pyx_n_u_r
#define __pyx_n_u_rb __pyx_mstate_global->__pyx_n_u_rb
#define __pyx_n_s_re __pyx_mstate_global->__pyx_n_s_re
#define __pyx_n_s_read __pyx_mstate_global->__pyx_n_s_read
#define __pyx_n_s_reference __pyx_mstate_global->__pyx_n_s_reference
#define __pyx_n_s_region __pyx_mstate_global->__pyx_n_s_region
#define __pyx_n_s_register_error __pyx_mstate_global->__pyx_n_s_register_error
#define __pyx_n_s_remove __pyx_mstate_global->__pyx_n_s_remove
#define __pyx_n_s_retval __pyx_mstate_global->__pyx_n_s_retval
#define __pyx_n_u_roh __pyx_mstate_global->__pyx_n_u_roh
#define __pyx_n_b_samtools __pyx_mstate_global->__pyx_n_b_samtools
#define __pyx_n_u_samtools __pyx_mstate_global->__pyx_n_u_samtools
#define __pyx_n_s_save_stdout __pyx_mstate_global->__pyx_n_s_save_stdout
#define __pyx_n_s_set_encoding_error_handler __pyx_mstate_global->__pyx_n_s_set_encoding_error_handler
#define __pyx_n_u_set_encoding_error_handler __pyx_mstate_global->__pyx_n_u_set_encoding_error_handler
#define __pyx_n_s_skip_next __pyx_mstate_global->__pyx_n_s_skip_next
#define __pyx_n_s_spec __pyx_mstate_global->__pyx_n_s_spec
#define __pyx_n_s_split __pyx_mstate_global->__pyx_n_s_split
#define __pyx_n_s_start __pyx_mstate_global->__pyx_n_s_start
#define __pyx_kp_u_start_out_of_range_i __pyx_mstate_global->__pyx_kp_u_start_out_of_range_i
#define __pyx_n_s_startswith __pyx_mstate_global->__pyx_n_s_startswith
#define __pyx_n_u_stats __pyx_mstate_global->__pyx_n_u_stats
#define __pyx_n_s_stderr_f __pyx_mstate_global->__pyx_n_s_stderr_f
#define __pyx_n_s_stderr_h __pyx_mstate_global->__pyx_n_s_stderr_h
#define __pyx_n_s_stdout_f __pyx_mstate_global->__pyx_n_s_stdout_f
#define __pyx_n_s_stdout_h __pyx_mstate_global->__pyx_n_s_stdout_h
#define __pyx_n_s_stdout_option __pyx_mstate_global->__pyx_n_s_stdout_option
#define __pyx_n_s_stop __pyx_mstate_global->__pyx_n_s_stop
#define __pyx_kp_u_stop_and_end_should_not_both_be __pyx_mstate_global->__pyx_kp_u_stop_and_end_should_not_both_be
#define __pyx_kp_u_stop_out_of_range_i __pyx_mstate_global->__pyx_kp_u_stop_out_of_range_i
#define __pyx_n_u_strict __pyx_mstate_global->__pyx_n_u_strict
#define __pyx_n_s_string __pyx_mstate_global->__pyx_n_s_string
#define __pyx_n_s_sys __pyx_mstate_global->__pyx_n_s_sys
#define __pyx_n_s_tempfile __pyx_mstate_global->__pyx_n_s_tempfile
#define __pyx_n_s_test __pyx_mstate_global->__pyx_n_s_test
#define __pyx_kp_u_threads __pyx_mstate_global->__pyx_kp_u_threads
#define __pyx_n_s_tobytes __pyx_mstate_global->__pyx_n_s_tobytes
#define __pyx_n_s_types __pyx_mstate_global->__pyx_n_s_types
#define __pyx_kp_u_utf_8 __pyx_mstate_global->__pyx_kp_u_utf_8
#define __pyx_n_u_view __pyx_mstate_global->__pyx_n_u_view
#define __pyx_int_1 __pyx_mstate_global->__pyx_int_1
#define __pyx_int_33 __pyx_mstate_global->__pyx_int_33
#define __pyx_int_neg_1 __pyx_mstate_global->__pyx_int_neg_1
#define __pyx_tuple__2 __pyx_mstate_global->__pyx_tuple__2
#define __pyx_tuple__3 __pyx_mstate_global->__pyx_tuple__3
#define __pyx_tuple__4 __pyx_mstate_global->__pyx_tuple__4
#define __pyx_tuple__5 __pyx_mstate_global->__pyx_tuple__5
#define __pyx_tuple__6 __pyx_mstate_global->__pyx_tuple__6
#define __pyx_tuple__9 __pyx_mstate_global->__pyx_tuple__9
#define __pyx_tuple__12 __pyx_mstate_global->__pyx_tuple__12
#define __pyx_tuple__16 __pyx_mstate_global->__pyx_tuple__16
#define __pyx_tuple__18 __pyx_mstate_global->__pyx_tuple__18
#define __pyx_tuple__19 __pyx_mstate_global->__pyx_tuple__19
#define __pyx_tuple__22 __pyx_mstate_global->__pyx_tuple__22
#define __pyx_tuple__25 __pyx_mstate_global->__pyx_tuple__25
#define __pyx_tuple__27 __pyx_mstate_global->__pyx_tuple__27
#define __pyx_tuple__29 __pyx_mstate_global->__pyx_tuple__29
#define __pyx_tuple__30 __pyx_mstate_global->__pyx_tuple__30
#define __pyx_tuple__32 __pyx_mstate_global->__pyx_tuple__32
#define __pyx_codeobj__13 __pyx_mstate_global->__pyx_codeobj__13
#define __pyx_codeobj__17 __pyx_mstate_global->__pyx_codeobj__17
#define __pyx_codeobj__20 __pyx_mstate_global->__pyx_codeobj__20
#define __pyx_codeobj__21 __pyx_mstate_global->__pyx_codeobj__21
#define __pyx_codeobj__23 __pyx_mstate_global->__pyx_codeobj__23
#define __pyx_codeobj__24 __pyx_mstate_global->__pyx_codeobj__24
#define __pyx_codeobj__26 __pyx_mstate_global->__pyx_codeobj__26
#define __pyx_codeobj__28 __pyx_mstate_global->__pyx_codeobj__28
#define __pyx_codeobj__31 __pyx_mstate_global->__pyx_codeobj__31
/* #### Code section: module_code ### */

/* "cpython/complex.pxd":19
 * 
 *         @property
 *         cdef inline double real(self):             # <<<<<<<<<<<<<<
 *             return self.cval.real
 * 
 */

static CYTHON_INLINE double __pyx_f_7cpython_7complex_7complex_4real_real(PyComplexObject *__pyx_v_self) {
  double __pyx_r;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("real", 0);

  /* "cpython/complex.pxd":20
 *         @property
 *         cdef inline double real(self):
 *             return self.cval.real             # <<<<<<<<<<<<<<
 * 
 *         @property
 */
  __pyx_r = __pyx_v_self->cval.real;
  goto __pyx_L0;

  /* "cpython/complex.pxd":19
 * 
 *         @property
 *         cdef inline double real(self):             # <<<<<<<<<<<<<<
 *             return self.cval.real
 * 
 */

  /* function exit code */
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "cpython/complex.pxd":23
 * 
 *         @property
 *         cdef inline double imag(self):             # <<<<<<<<<<<<<<
 *             return self.cval.imag
 * 
 */

static CYTHON_INLINE double __pyx_f_7cpython_7complex_7complex_4imag_imag(PyComplexObject *__pyx_v_self) {
  double __pyx_r;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("imag", 0);

  /* "cpython/complex.pxd":24
 *         @property
 *         cdef inline double imag(self):
 *             return self.cval.imag             # <<<<<<<<<<<<<<
 * 
 *     # PyTypeObject PyComplex_Type
 */
  __pyx_r = __pyx_v_self->cval.imag;
  goto __pyx_L0;

  /* "cpython/complex.pxd":23
 * 
 *         @property
 *         cdef inline double imag(self):             # <<<<<<<<<<<<<<
 *             return self.cval.imag
 * 
 */

  /* function exit code */
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "cpython/contextvars.pxd":112
 * 
 * 
 * cdef inline object get_value(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the default value of the context variable,
 */

static CYTHON_INLINE PyObject *__pyx_f_7cpython_11contextvars_get_value(PyObject *__pyx_v_var, struct __pyx_opt_args_7cpython_11contextvars_get_value *__pyx_optional_args) {
  PyObject *__pyx_v_default_value = ((PyObject *)Py_None);
  PyObject *__pyx_v_value;
  PyObject *__pyx_v_pyvalue = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  int __pyx_t_2;
  PyObject *__pyx_t_3 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("get_value", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_default_value = __pyx_optional_args->default_value;
    }
  }

  /* "cpython/contextvars.pxd":117
 *     or None if no such value or default was found.
 *     """
 *     cdef PyObject *value = NULL             # <<<<<<<<<<<<<<
 *     PyContextVar_Get(var, NULL, &value)
 *     if value is NULL:
 */
  __pyx_v_value = NULL;

  /* "cpython/contextvars.pxd":118
 *     """
 *     cdef PyObject *value = NULL
 *     PyContextVar_Get(var, NULL, &value)             # <<<<<<<<<<<<<<
 *     if value is NULL:
 *         # context variable does not have a default
 */
  __pyx_t_1 = PyContextVar_Get(__pyx_v_var, NULL, (&__pyx_v_value)); if (unlikely(__pyx_t_1 == ((int)-1))) __PYX_ERR(1, 118, __pyx_L1_error)

  /* "cpython/contextvars.pxd":119
 *     cdef PyObject *value = NULL
 *     PyContextVar_Get(var, NULL, &value)
 *     if value is NULL:             # <<<<<<<<<<<<<<
 *         # context variable does not have a default
 *         pyvalue = default_value
 */
  __pyx_t_2 = (__pyx_v_value == NULL);
  if (__pyx_t_2) {

    /* "cpython/contextvars.pxd":121
 *     if value is NULL:
 *         # context variable does not have a default
 *         pyvalue = default_value             # <<<<<<<<<<<<<<
 *     else:
 *         # value or default value of context variable
 */
    __Pyx_INCREF(__pyx_v_default_value);
    __pyx_v_pyvalue = __pyx_v_default_value;

    /* "cpython/contextvars.pxd":119
 *     cdef PyObject *value = NULL
 *     PyContextVar_Get(var, NULL, &value)
 *     if value is NULL:             # <<<<<<<<<<<<<<
 *         # context variable does not have a default
 *         pyvalue = default_value
 */
    goto __pyx_L3;
  }

  /* "cpython/contextvars.pxd":124
 *     else:
 *         # value or default value of context variable
 *         pyvalue = <object>value             # <<<<<<<<<<<<<<
 *         Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'
 *     return pyvalue
 */
  /*else*/ {
    __pyx_t_3 = ((PyObject *)__pyx_v_value);
    __Pyx_INCREF(__pyx_t_3);
    __pyx_v_pyvalue = __pyx_t_3;
    __pyx_t_3 = 0;

    /* "cpython/contextvars.pxd":125
 *         # value or default value of context variable
 *         pyvalue = <object>value
 *         Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'             # <<<<<<<<<<<<<<
 *     return pyvalue
 * 
 */
    Py_XDECREF(__pyx_v_value);
  }
  __pyx_L3:;

  /* "cpython/contextvars.pxd":126
 *         pyvalue = <object>value
 *         Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'
 *     return pyvalue             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_pyvalue);
  __pyx_r = __pyx_v_pyvalue;
  goto __pyx_L0;

  /* "cpython/contextvars.pxd":112
 * 
 * 
 * cdef inline object get_value(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the default value of the context variable,
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_AddTraceback("cpython.contextvars.get_value", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_pyvalue);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "cpython/contextvars.pxd":129
 * 
 * 
 * cdef inline object get_value_no_default(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the provided default value if no such value was found.
 */

static CYTHON_INLINE PyObject *__pyx_f_7cpython_11contextvars_get_value_no_default(PyObject *__pyx_v_var, struct __pyx_opt_args_7cpython_11contextvars_get_value_no_default *__pyx_optional_args) {
  PyObject *__pyx_v_default_value = ((PyObject *)Py_None);
  PyObject *__pyx_v_value;
  PyObject *__pyx_v_pyvalue = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("get_value_no_default", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_default_value = __pyx_optional_args->default_value;
    }
  }

  /* "cpython/contextvars.pxd":135
 *     Ignores the default value of the context variable, if any.
 *     """
 *     cdef PyObject *value = NULL             # <<<<<<<<<<<<<<
 *     PyContextVar_Get(var, <PyObject*>default_value, &value)
 *     # value of context variable or 'default_value'
 */
  __pyx_v_value = NULL;

  /* "cpython/contextvars.pxd":136
 *     """
 *     cdef PyObject *value = NULL
 *     PyContextVar_Get(var, <PyObject*>default_value, &value)             # <<<<<<<<<<<<<<
 *     # value of context variable or 'default_value'
 *     pyvalue = <object>value
 */
  __pyx_t_1 = PyContextVar_Get(__pyx_v_var, ((PyObject *)__pyx_v_default_value), (&__pyx_v_value)); if (unlikely(__pyx_t_1 == ((int)-1))) __PYX_ERR(1, 136, __pyx_L1_error)

  /* "cpython/contextvars.pxd":138
 *     PyContextVar_Get(var, <PyObject*>default_value, &value)
 *     # value of context variable or 'default_value'
 *     pyvalue = <object>value             # <<<<<<<<<<<<<<
 *     Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'
 *     return pyvalue
 */
  __pyx_t_2 = ((PyObject *)__pyx_v_value);
  __Pyx_INCREF(__pyx_t_2);
  __pyx_v_pyvalue = __pyx_t_2;
  __pyx_t_2 = 0;

  /* "cpython/contextvars.pxd":139
 *     # value of context variable or 'default_value'
 *     pyvalue = <object>value
 *     Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'             # <<<<<<<<<<<<<<
 *     return pyvalue
 */
  Py_XDECREF(__pyx_v_value);

  /* "cpython/contextvars.pxd":140
 *     pyvalue = <object>value
 *     Py_XDECREF(value)  # PyContextVar_Get() returned an owned reference as 'PyObject*'
 *     return pyvalue             # <<<<<<<<<<<<<<
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_pyvalue);
  __pyx_r = __pyx_v_pyvalue;
  goto __pyx_L0;

  /* "cpython/contextvars.pxd":129
 * 
 * 
 * cdef inline object get_value_no_default(var, default_value=None):             # <<<<<<<<<<<<<<
 *     """Return a new reference to the value of the context variable,
 *     or the provided default value if no such value was found.
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_AddTraceback("cpython.contextvars.get_value_no_default", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_pyvalue);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":104
 *             __data_union data
 * 
 *         def __getbuffer__(self, Py_buffer* info, int flags):             # <<<<<<<<<<<<<<
 *             # This implementation of getbuffer is geared towards Cython
 *             # requirements, and does not yet fulfill the PEP.
 */

/* Python wrapper */
CYTHON_UNUSED static int __pyx_pw_7cpython_5array_5array_1__getbuffer__(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags); /*proto*/
CYTHON_UNUSED static int __pyx_pw_7cpython_5array_5array_1__getbuffer__(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info, int __pyx_v_flags) {
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  int __pyx_r;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__getbuffer__ (wrapper)", 0);
  __pyx_kwvalues = __Pyx_KwValues_VARARGS(__pyx_args, __pyx_nargs);
  __pyx_r = __pyx_pf_7cpython_5array_5array___getbuffer__(((arrayobject *)__pyx_v_self), ((Py_buffer *)__pyx_v_info), ((int)__pyx_v_flags));

  /* function exit code */
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static int __pyx_pf_7cpython_5array_5array___getbuffer__(arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info, CYTHON_UNUSED int __pyx_v_flags) {
  PyObject *__pyx_v_item_count = NULL;
  int __pyx_r;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  char *__pyx_t_2;
  int __pyx_t_3;
  PyObject *__pyx_t_4 = NULL;
  Py_ssize_t __pyx_t_5;
  int __pyx_t_6;
  char __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  if (unlikely(__pyx_v_info == NULL)) {
    PyErr_SetString(PyExc_BufferError, "PyObject_GetBuffer: view==NULL argument is obsolete");
    return -1;
  }
  __Pyx_RefNannySetupContext("__getbuffer__", 0);
  __pyx_v_info->obj = Py_None; __Pyx_INCREF(Py_None);
  __Pyx_GIVEREF(__pyx_v_info->obj);

  /* "array.pxd":109
 *             # In particular strided access is always provided regardless
 *             # of flags
 *             item_count = Py_SIZE(self)             # <<<<<<<<<<<<<<
 * 
 *             info.suboffsets = NULL
 */
  __pyx_t_1 = PyInt_FromSsize_t(Py_SIZE(((PyObject *)__pyx_v_self))); if (unlikely(!__pyx_t_1)) __PYX_ERR(2, 109, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_v_item_count = __pyx_t_1;
  __pyx_t_1 = 0;

  /* "array.pxd":111
 *             item_count = Py_SIZE(self)
 * 
 *             info.suboffsets = NULL             # <<<<<<<<<<<<<<
 *             info.buf = self.data.as_chars
 *             info.readonly = 0
 */
  __pyx_v_info->suboffsets = NULL;

  /* "array.pxd":112
 * 
 *             info.suboffsets = NULL
 *             info.buf = self.data.as_chars             # <<<<<<<<<<<<<<
 *             info.readonly = 0
 *             info.ndim = 1
 */
  __pyx_t_2 = __pyx_v_self->data.as_chars;
  __pyx_v_info->buf = __pyx_t_2;

  /* "array.pxd":113
 *             info.suboffsets = NULL
 *             info.buf = self.data.as_chars
 *             info.readonly = 0             # <<<<<<<<<<<<<<
 *             info.ndim = 1
 *             info.itemsize = self.ob_descr.itemsize   # e.g. sizeof(float)
 */
  __pyx_v_info->readonly = 0;

  /* "array.pxd":114
 *             info.buf = self.data.as_chars
 *             info.readonly = 0
 *             info.ndim = 1             # <<<<<<<<<<<<<<
 *             info.itemsize = self.ob_descr.itemsize   # e.g. sizeof(float)
 *             info.len = info.itemsize * item_count
 */
  __pyx_v_info->ndim = 1;

  /* "array.pxd":115
 *             info.readonly = 0
 *             info.ndim = 1
 *             info.itemsize = self.ob_descr.itemsize   # e.g. sizeof(float)             # <<<<<<<<<<<<<<
 *             info.len = info.itemsize * item_count
 * 
 */
  __pyx_t_3 = __pyx_v_self->ob_descr->itemsize;
  __pyx_v_info->itemsize = __pyx_t_3;

  /* "array.pxd":116
 *             info.ndim = 1
 *             info.itemsize = self.ob_descr.itemsize   # e.g. sizeof(float)
 *             info.len = info.itemsize * item_count             # <<<<<<<<<<<<<<
 * 
 *             info.shape = <Py_ssize_t*> PyObject_Malloc(sizeof(Py_ssize_t) + 2)
 */
  __pyx_t_1 = PyInt_FromSsize_t(__pyx_v_info->itemsize); if (unlikely(!__pyx_t_1)) __PYX_ERR(2, 116, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_t_4 = PyNumber_Multiply(__pyx_t_1, __pyx_v_item_count); if (unlikely(!__pyx_t_4)) __PYX_ERR(2, 116, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __pyx_t_5 = __Pyx_PyIndex_AsSsize_t(__pyx_t_4); if (unlikely((__pyx_t_5 == (Py_ssize_t)-1) && PyErr_Occurred())) __PYX_ERR(2, 116, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  __pyx_v_info->len = __pyx_t_5;

  /* "array.pxd":118
 *             info.len = info.itemsize * item_count
 * 
 *             info.shape = <Py_ssize_t*> PyObject_Malloc(sizeof(Py_ssize_t) + 2)             # <<<<<<<<<<<<<<
 *             if not info.shape:
 *                 raise MemoryError()
 */
  __pyx_v_info->shape = ((Py_ssize_t *)PyObject_Malloc(((sizeof(Py_ssize_t)) + 2)));

  /* "array.pxd":119
 * 
 *             info.shape = <Py_ssize_t*> PyObject_Malloc(sizeof(Py_ssize_t) + 2)
 *             if not info.shape:             # <<<<<<<<<<<<<<
 *                 raise MemoryError()
 *             info.shape[0] = item_count      # constant regardless of resizing
 */
  __pyx_t_6 = (!(__pyx_v_info->shape != 0));
  if (unlikely(__pyx_t_6)) {

    /* "array.pxd":120
 *             info.shape = <Py_ssize_t*> PyObject_Malloc(sizeof(Py_ssize_t) + 2)
 *             if not info.shape:
 *                 raise MemoryError()             # <<<<<<<<<<<<<<
 *             info.shape[0] = item_count      # constant regardless of resizing
 *             info.strides = &info.itemsize
 */
    PyErr_NoMemory(); __PYX_ERR(2, 120, __pyx_L1_error)

    /* "array.pxd":119
 * 
 *             info.shape = <Py_ssize_t*> PyObject_Malloc(sizeof(Py_ssize_t) + 2)
 *             if not info.shape:             # <<<<<<<<<<<<<<
 *                 raise MemoryError()
 *             info.shape[0] = item_count      # constant regardless of resizing
 */
  }

  /* "array.pxd":121
 *             if not info.shape:
 *                 raise MemoryError()
 *             info.shape[0] = item_count      # constant regardless of resizing             # <<<<<<<<<<<<<<
 *             info.strides = &info.itemsize
 * 
 */
  __pyx_t_5 = __Pyx_PyIndex_AsSsize_t(__pyx_v_item_count); if (unlikely((__pyx_t_5 == (Py_ssize_t)-1) && PyErr_Occurred())) __PYX_ERR(2, 121, __pyx_L1_error)
  (__pyx_v_info->shape[0]) = __pyx_t_5;

  /* "array.pxd":122
 *                 raise MemoryError()
 *             info.shape[0] = item_count      # constant regardless of resizing
 *             info.strides = &info.itemsize             # <<<<<<<<<<<<<<
 * 
 *             info.format = <char*> (info.shape + 1)
 */
  __pyx_v_info->strides = (&__pyx_v_info->itemsize);

  /* "array.pxd":124
 *             info.strides = &info.itemsize
 * 
 *             info.format = <char*> (info.shape + 1)             # <<<<<<<<<<<<<<
 *             info.format[0] = self.ob_descr.typecode
 *             info.format[1] = 0
 */
  __pyx_v_info->format = ((char *)(__pyx_v_info->shape + 1));

  /* "array.pxd":125
 * 
 *             info.format = <char*> (info.shape + 1)
 *             info.format[0] = self.ob_descr.typecode             # <<<<<<<<<<<<<<
 *             info.format[1] = 0
 *             info.obj = self
 */
  __pyx_t_7 = __pyx_v_self->ob_descr->typecode;
  (__pyx_v_info->format[0]) = __pyx_t_7;

  /* "array.pxd":126
 *             info.format = <char*> (info.shape + 1)
 *             info.format[0] = self.ob_descr.typecode
 *             info.format[1] = 0             # <<<<<<<<<<<<<<
 *             info.obj = self
 * 
 */
  (__pyx_v_info->format[1]) = 0;

  /* "array.pxd":127
 *             info.format[0] = self.ob_descr.typecode
 *             info.format[1] = 0
 *             info.obj = self             # <<<<<<<<<<<<<<
 * 
 *         def __releasebuffer__(self, Py_buffer* info):
 */
  __Pyx_INCREF((PyObject *)__pyx_v_self);
  __Pyx_GIVEREF((PyObject *)__pyx_v_self);
  __Pyx_GOTREF(__pyx_v_info->obj);
  __Pyx_DECREF(__pyx_v_info->obj);
  __pyx_v_info->obj = ((PyObject *)__pyx_v_self);

  /* "array.pxd":104
 *             __data_union data
 * 
 *         def __getbuffer__(self, Py_buffer* info, int flags):             # <<<<<<<<<<<<<<
 *             # This implementation of getbuffer is geared towards Cython
 *             # requirements, and does not yet fulfill the PEP.
 */

  /* function exit code */
  __pyx_r = 0;
  goto __pyx_L0;
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_AddTraceback("cpython.array.array.__getbuffer__", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = -1;
  if (__pyx_v_info->obj != NULL) {
    __Pyx_GOTREF(__pyx_v_info->obj);
    __Pyx_DECREF(__pyx_v_info->obj); __pyx_v_info->obj = 0;
  }
  goto __pyx_L2;
  __pyx_L0:;
  if (__pyx_v_info->obj == Py_None) {
    __Pyx_GOTREF(__pyx_v_info->obj);
    __Pyx_DECREF(__pyx_v_info->obj); __pyx_v_info->obj = 0;
  }
  __pyx_L2:;
  __Pyx_XDECREF(__pyx_v_item_count);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":129
 *             info.obj = self
 * 
 *         def __releasebuffer__(self, Py_buffer* info):             # <<<<<<<<<<<<<<
 *             PyObject_Free(info.shape)
 * 
 */

/* Python wrapper */
CYTHON_UNUSED static void __pyx_pw_7cpython_5array_5array_3__releasebuffer__(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info); /*proto*/
CYTHON_UNUSED static void __pyx_pw_7cpython_5array_5array_3__releasebuffer__(PyObject *__pyx_v_self, Py_buffer *__pyx_v_info) {
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__releasebuffer__ (wrapper)", 0);
  __pyx_kwvalues = __Pyx_KwValues_VARARGS(__pyx_args, __pyx_nargs);
  __pyx_pf_7cpython_5array_5array_2__releasebuffer__(((arrayobject *)__pyx_v_self), ((Py_buffer *)__pyx_v_info));

  /* function exit code */
  __Pyx_RefNannyFinishContext();
}

static void __pyx_pf_7cpython_5array_5array_2__releasebuffer__(CYTHON_UNUSED arrayobject *__pyx_v_self, Py_buffer *__pyx_v_info) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__releasebuffer__", 0);

  /* "array.pxd":130
 * 
 *         def __releasebuffer__(self, Py_buffer* info):
 *             PyObject_Free(info.shape)             # <<<<<<<<<<<<<<
 * 
 *     array newarrayobject(PyTypeObject* type, Py_ssize_t size, arraydescr *descr)
 */
  PyObject_Free(__pyx_v_info->shape);

  /* "array.pxd":129
 *             info.obj = self
 * 
 *         def __releasebuffer__(self, Py_buffer* info):             # <<<<<<<<<<<<<<
 *             PyObject_Free(info.shape)
 * 
 */

  /* function exit code */
  __Pyx_RefNannyFinishContext();
}

/* "array.pxd":141
 * 
 * 
 * cdef inline array clone(array template, Py_ssize_t length, bint zero):             # <<<<<<<<<<<<<<
 *     """ fast creation of a new array, given a template array.
 *     type will be same as template.
 */

static CYTHON_INLINE arrayobject *__pyx_f_7cpython_5array_clone(arrayobject *__pyx_v_template, Py_ssize_t __pyx_v_length, int __pyx_v_zero) {
  arrayobject *__pyx_v_op = 0;
  arrayobject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_t_2;
  int __pyx_t_3;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("clone", 0);

  /* "array.pxd":145
 *     type will be same as template.
 *     if zero is true, new array will be initialized with zeroes."""
 *     cdef array op = newarrayobject(Py_TYPE(template), length, template.ob_descr)             # <<<<<<<<<<<<<<
 *     if zero and op is not None:
 *         memset(op.data.as_chars, 0, length * op.ob_descr.itemsize)
 */
  __pyx_t_1 = ((PyObject *)newarrayobject(Py_TYPE(((PyObject *)__pyx_v_template)), __pyx_v_length, __pyx_v_template->ob_descr)); if (unlikely(!__pyx_t_1)) __PYX_ERR(2, 145, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_v_op = ((arrayobject *)__pyx_t_1);
  __pyx_t_1 = 0;

  /* "array.pxd":146
 *     if zero is true, new array will be initialized with zeroes."""
 *     cdef array op = newarrayobject(Py_TYPE(template), length, template.ob_descr)
 *     if zero and op is not None:             # <<<<<<<<<<<<<<
 *         memset(op.data.as_chars, 0, length * op.ob_descr.itemsize)
 *     return op
 */
  if (__pyx_v_zero) {
  } else {
    __pyx_t_2 = __pyx_v_zero;
    goto __pyx_L4_bool_binop_done;
  }
  __pyx_t_3 = (((PyObject *)__pyx_v_op) != Py_None);
  __pyx_t_2 = __pyx_t_3;
  __pyx_L4_bool_binop_done:;
  if (__pyx_t_2) {

    /* "array.pxd":147
 *     cdef array op = newarrayobject(Py_TYPE(template), length, template.ob_descr)
 *     if zero and op is not None:
 *         memset(op.data.as_chars, 0, length * op.ob_descr.itemsize)             # <<<<<<<<<<<<<<
 *     return op
 * 
 */
    (void)(memset(__pyx_v_op->data.as_chars, 0, (__pyx_v_length * __pyx_v_op->ob_descr->itemsize)));

    /* "array.pxd":146
 *     if zero is true, new array will be initialized with zeroes."""
 *     cdef array op = newarrayobject(Py_TYPE(template), length, template.ob_descr)
 *     if zero and op is not None:             # <<<<<<<<<<<<<<
 *         memset(op.data.as_chars, 0, length * op.ob_descr.itemsize)
 *     return op
 */
  }

  /* "array.pxd":148
 *     if zero and op is not None:
 *         memset(op.data.as_chars, 0, length * op.ob_descr.itemsize)
 *     return op             # <<<<<<<<<<<<<<
 * 
 * cdef inline array copy(array self):
 */
  __Pyx_XDECREF((PyObject *)__pyx_r);
  __Pyx_INCREF((PyObject *)__pyx_v_op);
  __pyx_r = __pyx_v_op;
  goto __pyx_L0;

  /* "array.pxd":141
 * 
 * 
 * cdef inline array clone(array template, Py_ssize_t length, bint zero):             # <<<<<<<<<<<<<<
 *     """ fast creation of a new array, given a template array.
 *     type will be same as template.
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("cpython.array.clone", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF((PyObject *)__pyx_v_op);
  __Pyx_XGIVEREF((PyObject *)__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":150
 *     return op
 * 
 * cdef inline array copy(array self):             # <<<<<<<<<<<<<<
 *     """ make a copy of an array. """
 *     cdef array op = newarrayobject(Py_TYPE(self), Py_SIZE(self), self.ob_descr)
 */

static CYTHON_INLINE arrayobject *__pyx_f_7cpython_5array_copy(arrayobject *__pyx_v_self) {
  arrayobject *__pyx_v_op = 0;
  arrayobject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("copy", 0);

  /* "array.pxd":152
 * cdef inline array copy(array self):
 *     """ make a copy of an array. """
 *     cdef array op = newarrayobject(Py_TYPE(self), Py_SIZE(self), self.ob_descr)             # <<<<<<<<<<<<<<
 *     memcpy(op.data.as_chars, self.data.as_chars, Py_SIZE(op) * op.ob_descr.itemsize)
 *     return op
 */
  __pyx_t_1 = ((PyObject *)newarrayobject(Py_TYPE(((PyObject *)__pyx_v_self)), Py_SIZE(((PyObject *)__pyx_v_self)), __pyx_v_self->ob_descr)); if (unlikely(!__pyx_t_1)) __PYX_ERR(2, 152, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_v_op = ((arrayobject *)__pyx_t_1);
  __pyx_t_1 = 0;

  /* "array.pxd":153
 *     """ make a copy of an array. """
 *     cdef array op = newarrayobject(Py_TYPE(self), Py_SIZE(self), self.ob_descr)
 *     memcpy(op.data.as_chars, self.data.as_chars, Py_SIZE(op) * op.ob_descr.itemsize)             # <<<<<<<<<<<<<<
 *     return op
 * 
 */
  (void)(memcpy(__pyx_v_op->data.as_chars, __pyx_v_self->data.as_chars, (Py_SIZE(((PyObject *)__pyx_v_op)) * __pyx_v_op->ob_descr->itemsize)));

  /* "array.pxd":154
 *     cdef array op = newarrayobject(Py_TYPE(self), Py_SIZE(self), self.ob_descr)
 *     memcpy(op.data.as_chars, self.data.as_chars, Py_SIZE(op) * op.ob_descr.itemsize)
 *     return op             # <<<<<<<<<<<<<<
 * 
 * cdef inline int extend_buffer(array self, char* stuff, Py_ssize_t n) except -1:
 */
  __Pyx_XDECREF((PyObject *)__pyx_r);
  __Pyx_INCREF((PyObject *)__pyx_v_op);
  __pyx_r = __pyx_v_op;
  goto __pyx_L0;

  /* "array.pxd":150
 *     return op
 * 
 * cdef inline array copy(array self):             # <<<<<<<<<<<<<<
 *     """ make a copy of an array. """
 *     cdef array op = newarrayobject(Py_TYPE(self), Py_SIZE(self), self.ob_descr)
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("cpython.array.copy", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF((PyObject *)__pyx_v_op);
  __Pyx_XGIVEREF((PyObject *)__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":156
 *     return op
 * 
 * cdef inline int extend_buffer(array self, char* stuff, Py_ssize_t n) except -1:             # <<<<<<<<<<<<<<
 *     """ efficient appending of new stuff of same type
 *     (e.g. of same array type)
 */

static CYTHON_INLINE int __pyx_f_7cpython_5array_extend_buffer(arrayobject *__pyx_v_self, char *__pyx_v_stuff, Py_ssize_t __pyx_v_n) {
  Py_ssize_t __pyx_v_itemsize;
  Py_ssize_t __pyx_v_origsize;
  int __pyx_r;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("extend_buffer", 0);

  /* "array.pxd":160
 *     (e.g. of same array type)
 *     n: number of elements (not number of bytes!) """
 *     cdef Py_ssize_t itemsize = self.ob_descr.itemsize             # <<<<<<<<<<<<<<
 *     cdef Py_ssize_t origsize = Py_SIZE(self)
 *     resize_smart(self, origsize + n)
 */
  __pyx_t_1 = __pyx_v_self->ob_descr->itemsize;
  __pyx_v_itemsize = __pyx_t_1;

  /* "array.pxd":161
 *     n: number of elements (not number of bytes!) """
 *     cdef Py_ssize_t itemsize = self.ob_descr.itemsize
 *     cdef Py_ssize_t origsize = Py_SIZE(self)             # <<<<<<<<<<<<<<
 *     resize_smart(self, origsize + n)
 *     memcpy(self.data.as_chars + origsize * itemsize, stuff, n * itemsize)
 */
  __pyx_v_origsize = Py_SIZE(((PyObject *)__pyx_v_self));

  /* "array.pxd":162
 *     cdef Py_ssize_t itemsize = self.ob_descr.itemsize
 *     cdef Py_ssize_t origsize = Py_SIZE(self)
 *     resize_smart(self, origsize + n)             # <<<<<<<<<<<<<<
 *     memcpy(self.data.as_chars + origsize * itemsize, stuff, n * itemsize)
 *     return 0
 */
  __pyx_t_1 = resize_smart(__pyx_v_self, (__pyx_v_origsize + __pyx_v_n)); if (unlikely(__pyx_t_1 == ((int)-1))) __PYX_ERR(2, 162, __pyx_L1_error)

  /* "array.pxd":163
 *     cdef Py_ssize_t origsize = Py_SIZE(self)
 *     resize_smart(self, origsize + n)
 *     memcpy(self.data.as_chars + origsize * itemsize, stuff, n * itemsize)             # <<<<<<<<<<<<<<
 *     return 0
 * 
 */
  (void)(memcpy((__pyx_v_self->data.as_chars + (__pyx_v_origsize * __pyx_v_itemsize)), __pyx_v_stuff, (__pyx_v_n * __pyx_v_itemsize)));

  /* "array.pxd":164
 *     resize_smart(self, origsize + n)
 *     memcpy(self.data.as_chars + origsize * itemsize, stuff, n * itemsize)
 *     return 0             # <<<<<<<<<<<<<<
 * 
 * cdef inline int extend(array self, array other) except -1:
 */
  __pyx_r = 0;
  goto __pyx_L0;

  /* "array.pxd":156
 *     return op
 * 
 * cdef inline int extend_buffer(array self, char* stuff, Py_ssize_t n) except -1:             # <<<<<<<<<<<<<<
 *     """ efficient appending of new stuff of same type
 *     (e.g. of same array type)
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_AddTraceback("cpython.array.extend_buffer", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = -1;
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":166
 *     return 0
 * 
 * cdef inline int extend(array self, array other) except -1:             # <<<<<<<<<<<<<<
 *     """ extend array with data from another array; types must match. """
 *     if self.ob_descr.typecode != other.ob_descr.typecode:
 */

static CYTHON_INLINE int __pyx_f_7cpython_5array_extend(arrayobject *__pyx_v_self, arrayobject *__pyx_v_other) {
  int __pyx_r;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  int __pyx_t_2;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("extend", 0);

  /* "array.pxd":168
 * cdef inline int extend(array self, array other) except -1:
 *     """ extend array with data from another array; types must match. """
 *     if self.ob_descr.typecode != other.ob_descr.typecode:             # <<<<<<<<<<<<<<
 *         PyErr_BadArgument()
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))
 */
  __pyx_t_1 = (__pyx_v_self->ob_descr->typecode != __pyx_v_other->ob_descr->typecode);
  if (__pyx_t_1) {

    /* "array.pxd":169
 *     """ extend array with data from another array; types must match. """
 *     if self.ob_descr.typecode != other.ob_descr.typecode:
 *         PyErr_BadArgument()             # <<<<<<<<<<<<<<
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))
 * 
 */
    __pyx_t_2 = PyErr_BadArgument(); if (unlikely(__pyx_t_2 == ((int)0))) __PYX_ERR(2, 169, __pyx_L1_error)

    /* "array.pxd":168
 * cdef inline int extend(array self, array other) except -1:
 *     """ extend array with data from another array; types must match. """
 *     if self.ob_descr.typecode != other.ob_descr.typecode:             # <<<<<<<<<<<<<<
 *         PyErr_BadArgument()
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))
 */
  }

  /* "array.pxd":170
 *     if self.ob_descr.typecode != other.ob_descr.typecode:
 *         PyErr_BadArgument()
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))             # <<<<<<<<<<<<<<
 * 
 * cdef inline void zero(array self):
 */
  __pyx_t_2 = __pyx_f_7cpython_5array_extend_buffer(__pyx_v_self, __pyx_v_other->data.as_chars, Py_SIZE(((PyObject *)__pyx_v_other))); if (unlikely(__pyx_t_2 == ((int)-1))) __PYX_ERR(2, 170, __pyx_L1_error)
  __pyx_r = __pyx_t_2;
  goto __pyx_L0;

  /* "array.pxd":166
 *     return 0
 * 
 * cdef inline int extend(array self, array other) except -1:             # <<<<<<<<<<<<<<
 *     """ extend array with data from another array; types must match. """
 *     if self.ob_descr.typecode != other.ob_descr.typecode:
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_AddTraceback("cpython.array.extend", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = -1;
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "array.pxd":172
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))
 * 
 * cdef inline void zero(array self):             # <<<<<<<<<<<<<<
 *     """ set all elements of array to zero. """
 *     memset(self.data.as_chars, 0, Py_SIZE(self) * self.ob_descr.itemsize)
 */

static CYTHON_INLINE void __pyx_f_7cpython_5array_zero(arrayobject *__pyx_v_self) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("zero", 0);

  /* "array.pxd":174
 * cdef inline void zero(array self):
 *     """ set all elements of array to zero. """
 *     memset(self.data.as_chars, 0, Py_SIZE(self) * self.ob_descr.itemsize)             # <<<<<<<<<<<<<<
 */
  (void)(memset(__pyx_v_self->data.as_chars, 0, (Py_SIZE(((PyObject *)__pyx_v_self)) * __pyx_v_self->ob_descr->itemsize)));

  /* "array.pxd":172
 *     return extend_buffer(self, other.data.as_chars, Py_SIZE(other))
 * 
 * cdef inline void zero(array self):             # <<<<<<<<<<<<<<
 *     """ set all elements of array to zero. """
 *     memset(self.data.as_chars, 0, Py_SIZE(self) * self.ob_descr.itemsize)
 */

  /* function exit code */
  __Pyx_RefNannyFinishContext();
}

/* "pysam/libcutils.pyx":35
 * #################################################################
 * # Utility functions for quality string conversions
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:
 */

static PyObject *__pyx_pw_5pysam_9libcutils_1qualitystring_to_array(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static arrayobject *__pyx_f_5pysam_9libcutils_qualitystring_to_array(PyObject *__pyx_v_input_str, CYTHON_UNUSED int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array *__pyx_optional_args) {
  int __pyx_v_offset = ((int)33);
  PyObject *__pyx_v_qs = NULL;
  char __pyx_7genexpr__pyx_v_i;
  arrayobject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  char *__pyx_t_4;
  char *__pyx_t_5;
  char *__pyx_t_6;
  char *__pyx_t_7;
  PyObject *__pyx_t_8 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("qualitystring_to_array", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_offset = __pyx_optional_args->offset;
    }
  }

  /* "pysam/libcutils.pyx":37
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:             # <<<<<<<<<<<<<<
 *         return None
 *     qs = force_bytes(input_str)
 */
  __pyx_t_1 = (__pyx_v_input_str == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":38
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:
 *         return None             # <<<<<<<<<<<<<<
 *     qs = force_bytes(input_str)
 *     cdef char i
 */
    __Pyx_XDECREF((PyObject *)__pyx_r);
    __pyx_r = ((arrayobject *)Py_None); __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":37
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:             # <<<<<<<<<<<<<<
 *         return None
 *     qs = force_bytes(input_str)
 */
  }

  /* "pysam/libcutils.pyx":39
 *     if input_str is None:
 *         return None
 *     qs = force_bytes(input_str)             # <<<<<<<<<<<<<<
 *     cdef char i
 *     return c_array.array('B', [i - offset for i in qs])
 */
  __pyx_t_2 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_input_str, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 39, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __pyx_v_qs = ((PyObject*)__pyx_t_2);
  __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":41
 *     qs = force_bytes(input_str)
 *     cdef char i
 *     return c_array.array('B', [i - offset for i in qs])             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF((PyObject *)__pyx_r);
  { /* enter inner scope */
    __pyx_t_2 = PyList_New(0); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 41, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    if (unlikely(__pyx_v_qs == Py_None)) {
      PyErr_SetString(PyExc_TypeError, "'NoneType' is not iterable");
      __PYX_ERR(0, 41, __pyx_L1_error)
    }
    __Pyx_INCREF(__pyx_v_qs);
    __pyx_t_3 = __pyx_v_qs;
    __pyx_t_5 = PyBytes_AS_STRING(__pyx_t_3);
    __pyx_t_6 = (__pyx_t_5 + PyBytes_GET_SIZE(__pyx_t_3));
    for (__pyx_t_7 = __pyx_t_5; __pyx_t_7 < __pyx_t_6; __pyx_t_7++) {
      __pyx_t_4 = __pyx_t_7;
      __pyx_7genexpr__pyx_v_i = (__pyx_t_4[0]);
      __pyx_t_8 = __Pyx_PyInt_From_int((__pyx_7genexpr__pyx_v_i - __pyx_v_offset)); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 41, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_8);
      if (unlikely(__Pyx_ListComp_Append(__pyx_t_2, (PyObject*)__pyx_t_8))) __PYX_ERR(0, 41, __pyx_L1_error)
      __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
    }
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  } /* exit inner scope */
  __pyx_t_8 = PyTuple_New(2); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 41, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_8);
  __Pyx_INCREF(__pyx_n_u_B);
  __Pyx_GIVEREF(__pyx_n_u_B);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_8, 0, __pyx_n_u_B)) __PYX_ERR(0, 41, __pyx_L1_error);
  __Pyx_GIVEREF(__pyx_t_2);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_8, 1, __pyx_t_2)) __PYX_ERR(0, 41, __pyx_L1_error);
  __pyx_t_2 = 0;
  __pyx_t_2 = __Pyx_PyObject_Call(((PyObject *)__pyx_ptype_7cpython_5array_array), __pyx_t_8, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 41, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
  __pyx_r = ((arrayobject *)__pyx_t_2);
  __pyx_t_2 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":35
 * #################################################################
 * # Utility functions for quality string conversions
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_8);
  __Pyx_AddTraceback("pysam.libcutils.qualitystring_to_array", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_qs);
  __Pyx_XGIVEREF((PyObject *)__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_1qualitystring_to_array(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
PyDoc_STRVAR(__pyx_doc_5pysam_9libcutils_qualitystring_to_array, "convert a qualitystring to an array of quality values.");
static PyMethodDef __pyx_mdef_5pysam_9libcutils_1qualitystring_to_array = {"qualitystring_to_array", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_1qualitystring_to_array, __Pyx_METH_FASTCALL|METH_KEYWORDS, __pyx_doc_5pysam_9libcutils_qualitystring_to_array};
static PyObject *__pyx_pw_5pysam_9libcutils_1qualitystring_to_array(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_input_str = 0;
  int __pyx_v_offset;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[2] = {0,0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("qualitystring_to_array (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 35, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_input_str,&__pyx_n_s_offset,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_input_str)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 35, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
        CYTHON_FALLTHROUGH;
        case  1:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_offset);
          if (value) { values[1] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 35, __pyx_L3_error)
        }
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "qualitystring_to_array") < 0)) __PYX_ERR(0, 35, __pyx_L3_error)
      }
    } else {
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        break;
        default: goto __pyx_L5_argtuple_error;
      }
    }
    __pyx_v_input_str = values[0];
    if (values[1]) {
      __pyx_v_offset = __Pyx_PyInt_As_int(values[1]); if (unlikely((__pyx_v_offset == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 35, __pyx_L3_error)
    } else {
      __pyx_v_offset = ((int)33);
    }
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("qualitystring_to_array", 0, 1, 2, __pyx_nargs); __PYX_ERR(0, 35, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.qualitystring_to_array", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_qualitystring_to_array(__pyx_self, __pyx_v_input_str, __pyx_v_offset);

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_qualitystring_to_array(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_input_str, int __pyx_v_offset) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array __pyx_t_2;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("qualitystring_to_array", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_2.__pyx_n = 1;
  __pyx_t_2.offset = __pyx_v_offset;
  __pyx_t_1 = ((PyObject *)__pyx_f_5pysam_9libcutils_qualitystring_to_array(__pyx_v_input_str, 0, &__pyx_t_2)); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 35, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.qualitystring_to_array", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":44
 * 
 * 
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert an array of quality values to a string."""
 *     if qualities is None:
 */

static PyObject *__pyx_pw_5pysam_9libcutils_3array_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_array_to_qualitystring(arrayobject *__pyx_v_qualities, CYTHON_UNUSED int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring *__pyx_optional_args) {
  int __pyx_v_offset = ((int)33);
  int __pyx_v_x;
  arrayobject *__pyx_v_result = 0;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  Py_ssize_t __pyx_t_2;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  int __pyx_t_6;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("array_to_qualitystring", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_offset = __pyx_optional_args->offset;
    }
  }

  /* "pysam/libcutils.pyx":46
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):
 *     """convert an array of quality values to a string."""
 *     if qualities is None:             # <<<<<<<<<<<<<<
 *         return None
 *     cdef int x
 */
  __pyx_t_1 = (((PyObject *)__pyx_v_qualities) == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":47
 *     """convert an array of quality values to a string."""
 *     if qualities is None:
 *         return None             # <<<<<<<<<<<<<<
 *     cdef int x
 * 
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":46
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):
 *     """convert an array of quality values to a string."""
 *     if qualities is None:             # <<<<<<<<<<<<<<
 *         return None
 *     cdef int x
 */
  }

  /* "pysam/libcutils.pyx":51
 * 
 *     cdef c_array.array result
 *     result = c_array.clone(qualities, len(qualities), zero=False)             # <<<<<<<<<<<<<<
 * 
 *     for x from 0 <= x < len(qualities):
 */
  if (unlikely(((PyObject *)__pyx_v_qualities) == Py_None)) {
    PyErr_SetString(PyExc_TypeError, "object of type 'NoneType' has no len()");
    __PYX_ERR(0, 51, __pyx_L1_error)
  }
  __pyx_t_2 = Py_SIZE(((PyObject *)__pyx_v_qualities)); if (unlikely(__pyx_t_2 == ((Py_ssize_t)-1))) __PYX_ERR(0, 51, __pyx_L1_error)
  __pyx_t_3 = ((PyObject *)__pyx_f_7cpython_5array_clone(__pyx_v_qualities, __pyx_t_2, 0)); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 51, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_v_result = ((arrayobject *)__pyx_t_3);
  __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":53
 *     result = c_array.clone(qualities, len(qualities), zero=False)
 * 
 *     for x from 0 <= x < len(qualities):             # <<<<<<<<<<<<<<
 *         result[x] = qualities[x] + offset
 *     return force_str(result.tobytes())
 */
  if (unlikely(((PyObject *)__pyx_v_qualities) == Py_None)) {
    PyErr_SetString(PyExc_TypeError, "object of type 'NoneType' has no len()");
    __PYX_ERR(0, 53, __pyx_L1_error)
  }
  __pyx_t_2 = Py_SIZE(((PyObject *)__pyx_v_qualities)); if (unlikely(__pyx_t_2 == ((Py_ssize_t)-1))) __PYX_ERR(0, 53, __pyx_L1_error)
  for (__pyx_v_x = 0; __pyx_v_x < __pyx_t_2; __pyx_v_x++) {

    /* "pysam/libcutils.pyx":54
 * 
 *     for x from 0 <= x < len(qualities):
 *         result[x] = qualities[x] + offset             # <<<<<<<<<<<<<<
 *     return force_str(result.tobytes())
 * 
 */
    __pyx_t_3 = __Pyx_GetItemInt(((PyObject *)__pyx_v_qualities), __pyx_v_x, int, 1, __Pyx_PyInt_From_int, 0, 1, 1); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 54, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __pyx_t_4 = __Pyx_PyInt_From_int(__pyx_v_offset); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 54, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_4);
    __pyx_t_5 = PyNumber_Add(__pyx_t_3, __pyx_t_4); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 54, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_5);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
    if (unlikely((__Pyx_SetItemInt(((PyObject *)__pyx_v_result), __pyx_v_x, __pyx_t_5, int, 1, __Pyx_PyInt_From_int, 0, 1, 1) < 0))) __PYX_ERR(0, 54, __pyx_L1_error)
    __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
  }

  /* "pysam/libcutils.pyx":55
 *     for x from 0 <= x < len(qualities):
 *         result[x] = qualities[x] + offset
 *     return force_str(result.tobytes())             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_4 = __Pyx_PyObject_GetAttrStr(((PyObject *)__pyx_v_result), __pyx_n_s_tobytes); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 55, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __pyx_t_3 = NULL;
  __pyx_t_6 = 0;
  #if CYTHON_UNPACK_METHODS
  if (likely(PyMethod_Check(__pyx_t_4))) {
    __pyx_t_3 = PyMethod_GET_SELF(__pyx_t_4);
    if (likely(__pyx_t_3)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_4);
      __Pyx_INCREF(__pyx_t_3);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_4, function);
      __pyx_t_6 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[1] = {__pyx_t_3, };
    __pyx_t_5 = __Pyx_PyObject_FastCall(__pyx_t_4, __pyx_callargs+1-__pyx_t_6, 0+__pyx_t_6);
    __Pyx_XDECREF(__pyx_t_3); __pyx_t_3 = 0;
    if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 55, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_5);
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  }
  __pyx_t_4 = __pyx_f_5pysam_9libcutils_force_str(__pyx_t_5, NULL); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 55, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
  __pyx_r = __pyx_t_4;
  __pyx_t_4 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":44
 * 
 * 
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert an array of quality values to a string."""
 *     if qualities is None:
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_AddTraceback("pysam.libcutils.array_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF((PyObject *)__pyx_v_result);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_3array_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
PyDoc_STRVAR(__pyx_doc_5pysam_9libcutils_2array_to_qualitystring, "convert an array of quality values to a string.");
static PyMethodDef __pyx_mdef_5pysam_9libcutils_3array_to_qualitystring = {"array_to_qualitystring", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_3array_to_qualitystring, __Pyx_METH_FASTCALL|METH_KEYWORDS, __pyx_doc_5pysam_9libcutils_2array_to_qualitystring};
static PyObject *__pyx_pw_5pysam_9libcutils_3array_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  arrayobject *__pyx_v_qualities = 0;
  int __pyx_v_offset;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[2] = {0,0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("array_to_qualitystring (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 44, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_qualities,&__pyx_n_s_offset,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_qualities)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 44, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
        CYTHON_FALLTHROUGH;
        case  1:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_offset);
          if (value) { values[1] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 44, __pyx_L3_error)
        }
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "array_to_qualitystring") < 0)) __PYX_ERR(0, 44, __pyx_L3_error)
      }
    } else {
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        break;
        default: goto __pyx_L5_argtuple_error;
      }
    }
    __pyx_v_qualities = ((arrayobject *)values[0]);
    if (values[1]) {
      __pyx_v_offset = __Pyx_PyInt_As_int(values[1]); if (unlikely((__pyx_v_offset == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 44, __pyx_L3_error)
    } else {
      __pyx_v_offset = ((int)33);
    }
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("array_to_qualitystring", 0, 1, 2, __pyx_nargs); __PYX_ERR(0, 44, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.array_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  if (unlikely(!__Pyx_ArgTypeTest(((PyObject *)__pyx_v_qualities), __pyx_ptype_7cpython_5array_array, 1, "qualities", 0))) __PYX_ERR(0, 44, __pyx_L1_error)
  __pyx_r = __pyx_pf_5pysam_9libcutils_2array_to_qualitystring(__pyx_self, __pyx_v_qualities, __pyx_v_offset);

  /* function exit code */
  goto __pyx_L0;
  __pyx_L1_error:;
  __pyx_r = NULL;
  __pyx_L0:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_2array_to_qualitystring(CYTHON_UNUSED PyObject *__pyx_self, arrayobject *__pyx_v_qualities, int __pyx_v_offset) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring __pyx_t_2;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("array_to_qualitystring", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_2.__pyx_n = 1;
  __pyx_t_2.offset = __pyx_v_offset;
  __pyx_t_1 = __pyx_f_5pysam_9libcutils_array_to_qualitystring(__pyx_v_qualities, 0, &__pyx_t_2); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 44, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.array_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":58
 * 
 * 
 * cpdef qualities_to_qualitystring(qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a list or array of quality scores to the string
 *     representation used in the SAM format.
 */

static PyObject *__pyx_pw_5pysam_9libcutils_5qualities_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_qualities_to_qualitystring(PyObject *__pyx_v_qualities, CYTHON_UNUSED int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring *__pyx_optional_args) {
  int __pyx_v_offset = ((int)33);
  char __pyx_8genexpr1__pyx_v_x;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring __pyx_t_3;
  PyObject *__pyx_t_4 = NULL;
  Py_ssize_t __pyx_t_5;
  PyObject *(*__pyx_t_6)(PyObject *);
  PyObject *__pyx_t_7 = NULL;
  char __pyx_t_8;
  PyObject *__pyx_t_9 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("qualities_to_qualitystring", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_offset = __pyx_optional_args->offset;
    }
  }

  /* "pysam/libcutils.pyx":75
 *     """
 *     cdef char x
 *     if qualities is None:             # <<<<<<<<<<<<<<
 *         return None
 *     elif isinstance(qualities, c_array.array):
 */
  __pyx_t_1 = (__pyx_v_qualities == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":76
 *     cdef char x
 *     if qualities is None:
 *         return None             # <<<<<<<<<<<<<<
 *     elif isinstance(qualities, c_array.array):
 *         return array_to_qualitystring(qualities, offset=offset)
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":75
 *     """
 *     cdef char x
 *     if qualities is None:             # <<<<<<<<<<<<<<
 *         return None
 *     elif isinstance(qualities, c_array.array):
 */
  }

  /* "pysam/libcutils.pyx":77
 *     if qualities is None:
 *         return None
 *     elif isinstance(qualities, c_array.array):             # <<<<<<<<<<<<<<
 *         return array_to_qualitystring(qualities, offset=offset)
 *     else:
 */
  __pyx_t_1 = __Pyx_TypeCheck(__pyx_v_qualities, __pyx_ptype_7cpython_5array_array); 
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":78
 *         return None
 *     elif isinstance(qualities, c_array.array):
 *         return array_to_qualitystring(qualities, offset=offset)             # <<<<<<<<<<<<<<
 *     else:
 *         # tuples and lists
 */
    __Pyx_XDECREF(__pyx_r);
    if (!(likely(((__pyx_v_qualities) == Py_None) || likely(__Pyx_TypeTest(__pyx_v_qualities, __pyx_ptype_7cpython_5array_array))))) __PYX_ERR(0, 78, __pyx_L1_error)
    __pyx_t_3.__pyx_n = 1;
    __pyx_t_3.offset = __pyx_v_offset;
    __pyx_t_2 = __pyx_f_5pysam_9libcutils_array_to_qualitystring(((arrayobject *)__pyx_v_qualities), 0, &__pyx_t_3); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 78, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __pyx_r = __pyx_t_2;
    __pyx_t_2 = 0;
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":77
 *     if qualities is None:
 *         return None
 *     elif isinstance(qualities, c_array.array):             # <<<<<<<<<<<<<<
 *         return array_to_qualitystring(qualities, offset=offset)
 *     else:
 */
  }

  /* "pysam/libcutils.pyx":81
 *     else:
 *         # tuples and lists
 *         return force_str("".join([chr(x + offset) for x in qualities]))             # <<<<<<<<<<<<<<
 * 
 * 
 */
  /*else*/ {
    __Pyx_XDECREF(__pyx_r);
    { /* enter inner scope */
      __pyx_t_2 = PyList_New(0); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 81, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      if (likely(PyList_CheckExact(__pyx_v_qualities)) || PyTuple_CheckExact(__pyx_v_qualities)) {
        __pyx_t_4 = __pyx_v_qualities; __Pyx_INCREF(__pyx_t_4); __pyx_t_5 = 0;
        __pyx_t_6 = NULL;
      } else {
        __pyx_t_5 = -1; __pyx_t_4 = PyObject_GetIter(__pyx_v_qualities); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 81, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_4);
        __pyx_t_6 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_4); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 81, __pyx_L1_error)
      }
      for (;;) {
        if (likely(!__pyx_t_6)) {
          if (likely(PyList_CheckExact(__pyx_t_4))) {
            if (__pyx_t_5 >= PyList_GET_SIZE(__pyx_t_4)) break;
            #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
            __pyx_t_7 = PyList_GET_ITEM(__pyx_t_4, __pyx_t_5); __Pyx_INCREF(__pyx_t_7); __pyx_t_5++; if (unlikely((0 < 0))) __PYX_ERR(0, 81, __pyx_L1_error)
            #else
            __pyx_t_7 = PySequence_ITEM(__pyx_t_4, __pyx_t_5); __pyx_t_5++; if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 81, __pyx_L1_error)
            __Pyx_GOTREF(__pyx_t_7);
            #endif
          } else {
            if (__pyx_t_5 >= PyTuple_GET_SIZE(__pyx_t_4)) break;
            #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
            __pyx_t_7 = PyTuple_GET_ITEM(__pyx_t_4, __pyx_t_5); __Pyx_INCREF(__pyx_t_7); __pyx_t_5++; if (unlikely((0 < 0))) __PYX_ERR(0, 81, __pyx_L1_error)
            #else
            __pyx_t_7 = PySequence_ITEM(__pyx_t_4, __pyx_t_5); __pyx_t_5++; if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 81, __pyx_L1_error)
            __Pyx_GOTREF(__pyx_t_7);
            #endif
          }
        } else {
          __pyx_t_7 = __pyx_t_6(__pyx_t_4);
          if (unlikely(!__pyx_t_7)) {
            PyObject* exc_type = PyErr_Occurred();
            if (exc_type) {
              if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) PyErr_Clear();
              else __PYX_ERR(0, 81, __pyx_L1_error)
            }
            break;
          }
          __Pyx_GOTREF(__pyx_t_7);
        }
        __pyx_t_8 = __Pyx_PyInt_As_char(__pyx_t_7); if (unlikely((__pyx_t_8 == (char)-1) && PyErr_Occurred())) __PYX_ERR(0, 81, __pyx_L1_error)
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
        __pyx_8genexpr1__pyx_v_x = __pyx_t_8;
        __pyx_t_7 = __Pyx_PyInt_From_int((__pyx_8genexpr1__pyx_v_x + __pyx_v_offset)); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 81, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __pyx_t_9 = __Pyx_PyObject_CallOneArg(__pyx_builtin_chr, __pyx_t_7); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 81, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_9);
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
        if (unlikely(__Pyx_ListComp_Append(__pyx_t_2, (PyObject*)__pyx_t_9))) __PYX_ERR(0, 81, __pyx_L1_error)
        __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
      }
      __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
    } /* exit inner scope */
    __pyx_t_4 = PyUnicode_Join(__pyx_kp_u_, __pyx_t_2); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 81, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_4);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __pyx_t_2 = __pyx_f_5pysam_9libcutils_force_str(__pyx_t_4, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 81, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
    __pyx_r = __pyx_t_2;
    __pyx_t_2 = 0;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":58
 * 
 * 
 * cpdef qualities_to_qualitystring(qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a list or array of quality scores to the string
 *     representation used in the SAM format.
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_7);
  __Pyx_XDECREF(__pyx_t_9);
  __Pyx_AddTraceback("pysam.libcutils.qualities_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_5qualities_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
PyDoc_STRVAR(__pyx_doc_5pysam_9libcutils_4qualities_to_qualitystring, "convert a list or array of quality scores to the string\n    representation used in the SAM format.\n\n    Parameters\n    ----------\n    offset : int\n        offset to be added to the quality scores to arrive at\n        the characters of the quality string (default=33).\n\n    Returns\n    -------\n    string\n         a quality string\n\n    ");
static PyMethodDef __pyx_mdef_5pysam_9libcutils_5qualities_to_qualitystring = {"qualities_to_qualitystring", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_5qualities_to_qualitystring, __Pyx_METH_FASTCALL|METH_KEYWORDS, __pyx_doc_5pysam_9libcutils_4qualities_to_qualitystring};
static PyObject *__pyx_pw_5pysam_9libcutils_5qualities_to_qualitystring(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_qualities = 0;
  int __pyx_v_offset;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[2] = {0,0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("qualities_to_qualitystring (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 58, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_qualities,&__pyx_n_s_offset,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_qualities)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 58, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
        CYTHON_FALLTHROUGH;
        case  1:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_offset);
          if (value) { values[1] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 58, __pyx_L3_error)
        }
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "qualities_to_qualitystring") < 0)) __PYX_ERR(0, 58, __pyx_L3_error)
      }
    } else {
      switch (__pyx_nargs) {
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        break;
        default: goto __pyx_L5_argtuple_error;
      }
    }
    __pyx_v_qualities = values[0];
    if (values[1]) {
      __pyx_v_offset = __Pyx_PyInt_As_int(values[1]); if (unlikely((__pyx_v_offset == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 58, __pyx_L3_error)
    } else {
      __pyx_v_offset = ((int)33);
    }
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("qualities_to_qualitystring", 0, 1, 2, __pyx_nargs); __PYX_ERR(0, 58, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.qualities_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_4qualities_to_qualitystring(__pyx_self, __pyx_v_qualities, __pyx_v_offset);

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_4qualities_to_qualitystring(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_qualities, int __pyx_v_offset) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring __pyx_t_2;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("qualities_to_qualitystring", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_2.__pyx_n = 1;
  __pyx_t_2.offset = __pyx_v_offset;
  __pyx_t_1 = __pyx_f_5pysam_9libcutils_qualities_to_qualitystring(__pyx_v_qualities, 0, &__pyx_t_2); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 58, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.qualities_to_qualitystring", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":89
 * 
 * # Codec error handler that just interprets each bad byte as ISO-8859-1.
 * def latin1_replace(exception):             # <<<<<<<<<<<<<<
 *     return (chr(exception.object[exception.start]), exception.end)
 * 
 */

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_7latin1_replace(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyMethodDef __pyx_mdef_5pysam_9libcutils_7latin1_replace = {"latin1_replace", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_7latin1_replace, __Pyx_METH_FASTCALL|METH_KEYWORDS, 0};
static PyObject *__pyx_pw_5pysam_9libcutils_7latin1_replace(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_exception = 0;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[1] = {0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("latin1_replace (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 89, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_exception,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_exception)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 89, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "latin1_replace") < 0)) __PYX_ERR(0, 89, __pyx_L3_error)
      }
    } else if (unlikely(__pyx_nargs != 1)) {
      goto __pyx_L5_argtuple_error;
    } else {
      values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
    }
    __pyx_v_exception = values[0];
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("latin1_replace", 1, 1, 1, __pyx_nargs); __PYX_ERR(0, 89, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.latin1_replace", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_6latin1_replace(__pyx_self, __pyx_v_exception);

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_6latin1_replace(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_exception) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("latin1_replace", 0);

  /* "pysam/libcutils.pyx":90
 * # Codec error handler that just interprets each bad byte as ISO-8859-1.
 * def latin1_replace(exception):
 *     return (chr(exception.object[exception.start]), exception.end)             # <<<<<<<<<<<<<<
 * 
 * register_error('pysam.latin1replace', latin1_replace)
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_1 = __Pyx_PyObject_GetAttrStr(__pyx_v_exception, __pyx_n_s_object); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_t_2 = __Pyx_PyObject_GetAttrStr(__pyx_v_exception, __pyx_n_s_start); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __pyx_t_3 = __Pyx_PyObject_GetItem(__pyx_t_1, __pyx_t_2); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __pyx_t_2 = __Pyx_PyObject_CallOneArg(__pyx_builtin_chr, __pyx_t_3); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_v_exception, __pyx_n_s_end); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_t_1 = PyTuple_New(2); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 90, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __Pyx_GIVEREF(__pyx_t_2);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_1, 0, __pyx_t_2)) __PYX_ERR(0, 90, __pyx_L1_error);
  __Pyx_GIVEREF(__pyx_t_3);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_1, 1, __pyx_t_3)) __PYX_ERR(0, 90, __pyx_L1_error);
  __pyx_t_2 = 0;
  __pyx_t_3 = 0;
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":89
 * 
 * # Codec error handler that just interprets each bad byte as ISO-8859-1.
 * def latin1_replace(exception):             # <<<<<<<<<<<<<<
 *     return (chr(exception.object[exception.start]), exception.end)
 * 
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_AddTraceback("pysam.libcutils.latin1_replace", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":97
 * cdef str ERROR_HANDLER = 'strict'
 * 
 * cpdef get_encoding_error_handler():             # <<<<<<<<<<<<<<
 *     return ERROR_HANDLER
 * 
 */

static PyObject *__pyx_pw_5pysam_9libcutils_9get_encoding_error_handler(PyObject *__pyx_self, CYTHON_UNUSED PyObject *unused); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_get_encoding_error_handler(CYTHON_UNUSED int __pyx_skip_dispatch) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("get_encoding_error_handler", 0);

  /* "pysam/libcutils.pyx":98
 * 
 * cpdef get_encoding_error_handler():
 *     return ERROR_HANDLER             # <<<<<<<<<<<<<<
 * 
 * cpdef set_encoding_error_handler(name):
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __pyx_r = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":97
 * cdef str ERROR_HANDLER = 'strict'
 * 
 * cpdef get_encoding_error_handler():             # <<<<<<<<<<<<<<
 *     return ERROR_HANDLER
 * 
 */

  /* function exit code */
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_9get_encoding_error_handler(PyObject *__pyx_self, CYTHON_UNUSED PyObject *unused); /*proto*/
static PyMethodDef __pyx_mdef_5pysam_9libcutils_9get_encoding_error_handler = {"get_encoding_error_handler", (PyCFunction)__pyx_pw_5pysam_9libcutils_9get_encoding_error_handler, METH_NOARGS, 0};
static PyObject *__pyx_pw_5pysam_9libcutils_9get_encoding_error_handler(PyObject *__pyx_self, CYTHON_UNUSED PyObject *unused) {
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("get_encoding_error_handler (wrapper)", 0);
  __pyx_kwvalues = __Pyx_KwValues_VARARGS(__pyx_args, __pyx_nargs);
  __pyx_r = __pyx_pf_5pysam_9libcutils_8get_encoding_error_handler(__pyx_self);

  /* function exit code */
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_8get_encoding_error_handler(CYTHON_UNUSED PyObject *__pyx_self) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("get_encoding_error_handler", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_1 = __pyx_f_5pysam_9libcutils_get_encoding_error_handler(0); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 97, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.get_encoding_error_handler", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":100
 *     return ERROR_HANDLER
 * 
 * cpdef set_encoding_error_handler(name):             # <<<<<<<<<<<<<<
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER
 */

static PyObject *__pyx_pw_5pysam_9libcutils_11set_encoding_error_handler(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_set_encoding_error_handler(PyObject *__pyx_v_name, CYTHON_UNUSED int __pyx_skip_dispatch) {
  PyObject *__pyx_v_previous = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("set_encoding_error_handler", 0);

  /* "pysam/libcutils.pyx":102
 * cpdef set_encoding_error_handler(name):
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER             # <<<<<<<<<<<<<<
 *     ERROR_HANDLER = name
 *     return previous
 */
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __pyx_v_previous = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;

  /* "pysam/libcutils.pyx":103
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER
 *     ERROR_HANDLER = name             # <<<<<<<<<<<<<<
 *     return previous
 * 
 */
  if (!(likely(PyUnicode_CheckExact(__pyx_v_name))||((__pyx_v_name) == Py_None) || __Pyx_RaiseUnexpectedTypeError("unicode", __pyx_v_name))) __PYX_ERR(0, 103, __pyx_L1_error)
  __pyx_t_1 = __pyx_v_name;
  __Pyx_INCREF(__pyx_t_1);
  __Pyx_XGOTREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __Pyx_DECREF_SET(__pyx_v_5pysam_9libcutils_ERROR_HANDLER, ((PyObject*)__pyx_t_1));
  __Pyx_GIVEREF(__pyx_t_1);
  __pyx_t_1 = 0;

  /* "pysam/libcutils.pyx":104
 *     previous = ERROR_HANDLER
 *     ERROR_HANDLER = name
 *     return previous             # <<<<<<<<<<<<<<
 * 
 * ########################################################################
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_previous);
  __pyx_r = __pyx_v_previous;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":100
 *     return ERROR_HANDLER
 * 
 * cpdef set_encoding_error_handler(name):             # <<<<<<<<<<<<<<
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.set_encoding_error_handler", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_previous);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_11set_encoding_error_handler(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyMethodDef __pyx_mdef_5pysam_9libcutils_11set_encoding_error_handler = {"set_encoding_error_handler", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_11set_encoding_error_handler, __Pyx_METH_FASTCALL|METH_KEYWORDS, 0};
static PyObject *__pyx_pw_5pysam_9libcutils_11set_encoding_error_handler(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_name = 0;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[1] = {0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("set_encoding_error_handler (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 100, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_name,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_name)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 100, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "set_encoding_error_handler") < 0)) __PYX_ERR(0, 100, __pyx_L3_error)
      }
    } else if (unlikely(__pyx_nargs != 1)) {
      goto __pyx_L5_argtuple_error;
    } else {
      values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
    }
    __pyx_v_name = values[0];
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("set_encoding_error_handler", 1, 1, 1, __pyx_nargs); __PYX_ERR(0, 100, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.set_encoding_error_handler", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_10set_encoding_error_handler(__pyx_self, __pyx_v_name);

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_10set_encoding_error_handler(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_name) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("set_encoding_error_handler", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_1 = __pyx_f_5pysam_9libcutils_set_encoding_error_handler(__pyx_v_name, 0); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 100, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.set_encoding_error_handler", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":110
 * ########################################################################
 * 
 * cdef from_string_and_size(const char* s, size_t length):             # <<<<<<<<<<<<<<
 *     return s[:length].decode('utf-8', ERROR_HANDLER)
 * 
 */

static PyObject *__pyx_f_5pysam_9libcutils_from_string_and_size(char const *__pyx_v_s, size_t __pyx_v_length) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  int __pyx_t_4;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("from_string_and_size", 0);

  /* "pysam/libcutils.pyx":111
 * 
 * cdef from_string_and_size(const char* s, size_t length):
 *     return s[:length].decode('utf-8', ERROR_HANDLER)             # <<<<<<<<<<<<<<
 * 
 * # filename encoding (adapted from lxml.etree.pyx)
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_2 = __Pyx_PyBytes_FromStringAndSize(__pyx_v_s + 0, __pyx_v_length - 0); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 111, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_t_2, __pyx_n_s_decode); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 111, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __pyx_t_2 = NULL;
  __pyx_t_4 = 0;
  #if CYTHON_UNPACK_METHODS
  if (likely(PyMethod_Check(__pyx_t_3))) {
    __pyx_t_2 = PyMethod_GET_SELF(__pyx_t_3);
    if (likely(__pyx_t_2)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_3);
      __Pyx_INCREF(__pyx_t_2);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_3, function);
      __pyx_t_4 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[3] = {__pyx_t_2, __pyx_kp_u_utf_8, __pyx_v_5pysam_9libcutils_ERROR_HANDLER};
    __pyx_t_1 = __Pyx_PyObject_FastCall(__pyx_t_3, __pyx_callargs+1-__pyx_t_4, 2+__pyx_t_4);
    __Pyx_XDECREF(__pyx_t_2); __pyx_t_2 = 0;
    if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 111, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_1);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  }
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":110
 * ########################################################################
 * 
 * cdef from_string_and_size(const char* s, size_t length):             # <<<<<<<<<<<<<<
 *     return s[:length].decode('utf-8', ERROR_HANDLER)
 * 
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_AddTraceback("pysam.libcutils.from_string_and_size", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":117
 * cdef str TEXT_ENCODING = 'utf-8'
 * 
 * cdef bytes encode_filename(object filename):             # <<<<<<<<<<<<<<
 *     """Make sure a filename is 8-bit encoded (or None)."""
 *     if filename is None:
 */

static PyObject *__pyx_f_5pysam_9libcutils_encode_filename(PyObject *__pyx_v_filename) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  int __pyx_t_5;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("encode_filename", 0);

  /* "pysam/libcutils.pyx":119
 * cdef bytes encode_filename(object filename):
 *     """Make sure a filename is 8-bit encoded (or None)."""
 *     if filename is None:             # <<<<<<<<<<<<<<
 *         return None
 *     return os.fsencode(filename)
 */
  __pyx_t_1 = (__pyx_v_filename == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":120
 *     """Make sure a filename is 8-bit encoded (or None)."""
 *     if filename is None:
 *         return None             # <<<<<<<<<<<<<<
 *     return os.fsencode(filename)
 * 
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = ((PyObject*)Py_None); __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":119
 * cdef bytes encode_filename(object filename):
 *     """Make sure a filename is 8-bit encoded (or None)."""
 *     if filename is None:             # <<<<<<<<<<<<<<
 *         return None
 *     return os.fsencode(filename)
 */
  }

  /* "pysam/libcutils.pyx":121
 *     if filename is None:
 *         return None
 *     return os.fsencode(filename)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_GetModuleGlobalName(__pyx_t_3, __pyx_n_s_os); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 121, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_t_4 = __Pyx_PyObject_GetAttrStr(__pyx_t_3, __pyx_n_s_fsencode); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 121, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __pyx_t_3 = NULL;
  __pyx_t_5 = 0;
  #if CYTHON_UNPACK_METHODS
  if (unlikely(PyMethod_Check(__pyx_t_4))) {
    __pyx_t_3 = PyMethod_GET_SELF(__pyx_t_4);
    if (likely(__pyx_t_3)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_4);
      __Pyx_INCREF(__pyx_t_3);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_4, function);
      __pyx_t_5 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[2] = {__pyx_t_3, __pyx_v_filename};
    __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_4, __pyx_callargs+1-__pyx_t_5, 1+__pyx_t_5);
    __Pyx_XDECREF(__pyx_t_3); __pyx_t_3 = 0;
    if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 121, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  }
  if (!(likely(PyBytes_CheckExact(__pyx_t_2))||((__pyx_t_2) == Py_None) || __Pyx_RaiseUnexpectedTypeError("bytes", __pyx_t_2))) __PYX_ERR(0, 121, __pyx_L1_error)
  __pyx_r = ((PyObject*)__pyx_t_2);
  __pyx_t_2 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":117
 * cdef str TEXT_ENCODING = 'utf-8'
 * 
 * cdef bytes encode_filename(object filename):             # <<<<<<<<<<<<<<
 *     """Make sure a filename is 8-bit encoded (or None)."""
 *     if filename is None:
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_AddTraceback("pysam.libcutils.encode_filename", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":124
 * 
 * 
 * cdef bytes force_bytes(object s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """convert string or unicode object to bytes, assuming
 *     utf8 encoding.
 */

static PyObject *__pyx_f_5pysam_9libcutils_force_bytes(PyObject *__pyx_v_s, struct __pyx_opt_args_5pysam_9libcutils_force_bytes *__pyx_optional_args) {
  PyObject *__pyx_v_encoding = ((PyObject *)Py_None);
  PyObject *__pyx_v_errors = ((PyObject *)Py_None);
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("force_bytes", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_encoding = __pyx_optional_args->encoding;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_errors = __pyx_optional_args->errors;
      }
    }
  }

  /* "pysam/libcutils.pyx":128
 *     utf8 encoding.
 *     """
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     elif PyBytes_Check(s):
 */
  __pyx_t_1 = (__pyx_v_s == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":129
 *     """
 *     if s is None:
 *         return None             # <<<<<<<<<<<<<<
 *     elif PyBytes_Check(s):
 *         return s
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = ((PyObject*)Py_None); __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":128
 *     utf8 encoding.
 *     """
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     elif PyBytes_Check(s):
 */
  }

  /* "pysam/libcutils.pyx":130
 *     if s is None:
 *         return None
 *     elif PyBytes_Check(s):             # <<<<<<<<<<<<<<
 *         return s
 *     elif PyUnicode_Check(s):
 */
  __pyx_t_1 = PyBytes_Check(__pyx_v_s);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":131
 *         return None
 *     elif PyBytes_Check(s):
 *         return s             # <<<<<<<<<<<<<<
 *     elif PyUnicode_Check(s):
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
    __Pyx_XDECREF(__pyx_r);
    if (!(likely(PyBytes_CheckExact(__pyx_v_s))||((__pyx_v_s) == Py_None) || __Pyx_RaiseUnexpectedTypeError("bytes", __pyx_v_s))) __PYX_ERR(0, 131, __pyx_L1_error)
    __Pyx_INCREF(__pyx_v_s);
    __pyx_r = ((PyObject*)__pyx_v_s);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":130
 *     if s is None:
 *         return None
 *     elif PyBytes_Check(s):             # <<<<<<<<<<<<<<
 *         return s
 *     elif PyUnicode_Check(s):
 */
  }

  /* "pysam/libcutils.pyx":132
 *     elif PyBytes_Check(s):
 *         return s
 *     elif PyUnicode_Check(s):             # <<<<<<<<<<<<<<
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     else:
 */
  __pyx_t_1 = PyUnicode_Check(__pyx_v_s);
  if (likely(__pyx_t_1)) {

    /* "pysam/libcutils.pyx":133
 *         return s
 *     elif PyUnicode_Check(s):
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)             # <<<<<<<<<<<<<<
 *     else:
 *         raise TypeError("Argument must be string, bytes or unicode.")
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_v_s, __pyx_n_s_encode); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 133, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_encoding); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 133, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_encoding);
      __pyx_t_4 = __pyx_v_encoding;
      goto __pyx_L4_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
    __pyx_t_4 = __pyx_v_5pysam_9libcutils_TEXT_ENCODING;
    __pyx_L4_bool_binop_done:;
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_errors); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 133, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_errors);
      __pyx_t_5 = __pyx_v_errors;
      goto __pyx_L6_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
    __pyx_t_5 = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
    __pyx_L6_bool_binop_done:;
    __pyx_t_6 = NULL;
    __pyx_t_7 = 0;
    #if CYTHON_UNPACK_METHODS
    if (likely(PyMethod_Check(__pyx_t_3))) {
      __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_3);
      if (likely(__pyx_t_6)) {
        PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_3);
        __Pyx_INCREF(__pyx_t_6);
        __Pyx_INCREF(function);
        __Pyx_DECREF_SET(__pyx_t_3, function);
        __pyx_t_7 = 1;
      }
    }
    #endif
    {
      PyObject *__pyx_callargs[3] = {__pyx_t_6, __pyx_t_4, __pyx_t_5};
      __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_3, __pyx_callargs+1-__pyx_t_7, 2+__pyx_t_7);
      __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
      __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
      __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
      if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 133, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    }
    if (!(likely(PyBytes_CheckExact(__pyx_t_2))||((__pyx_t_2) == Py_None) || __Pyx_RaiseUnexpectedTypeError("bytes", __pyx_t_2))) __PYX_ERR(0, 133, __pyx_L1_error)
    __pyx_r = ((PyObject*)__pyx_t_2);
    __pyx_t_2 = 0;
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":132
 *     elif PyBytes_Check(s):
 *         return s
 *     elif PyUnicode_Check(s):             # <<<<<<<<<<<<<<
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     else:
 */
  }

  /* "pysam/libcutils.pyx":135
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     else:
 *         raise TypeError("Argument must be string, bytes or unicode.")             # <<<<<<<<<<<<<<
 * 
 * 
 */
  /*else*/ {
    __pyx_t_2 = __Pyx_PyObject_Call(__pyx_builtin_TypeError, __pyx_tuple__2, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 135, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_Raise(__pyx_t_2, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __PYX_ERR(0, 135, __pyx_L1_error)
  }

  /* "pysam/libcutils.pyx":124
 * 
 * 
 * cdef bytes force_bytes(object s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """convert string or unicode object to bytes, assuming
 *     utf8 encoding.
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_AddTraceback("pysam.libcutils.force_bytes", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":138
 * 
 * 
 * cdef charptr_to_str(const char* s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

static PyObject *__pyx_f_5pysam_9libcutils_charptr_to_str(char const *__pyx_v_s, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str *__pyx_optional_args) {
  PyObject *__pyx_v_encoding = ((PyObject *)Py_None);
  PyObject *__pyx_v_errors = ((PyObject *)Py_None);
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("charptr_to_str", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_encoding = __pyx_optional_args->encoding;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_errors = __pyx_optional_args->errors;
      }
    }
  }

  /* "pysam/libcutils.pyx":139
 * 
 * cdef charptr_to_str(const char* s, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
  __pyx_t_1 = (__pyx_v_s == NULL);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":140
 * cdef charptr_to_str(const char* s, encoding=None, errors=None):
 *     if s == NULL:
 *         return None             # <<<<<<<<<<<<<<
 *     return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 * 
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":139
 * 
 * cdef charptr_to_str(const char* s, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
  }

  /* "pysam/libcutils.pyx":141
 *     if s == NULL:
 *         return None
 *     return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_3 = __Pyx_PyBytes_FromString(__pyx_v_s); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 141, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_t_4 = __Pyx_PyObject_GetAttrStr(__pyx_t_3, __pyx_n_s_decode); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 141, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_encoding); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 141, __pyx_L1_error)
  if (!__pyx_t_1) {
  } else {
    __Pyx_INCREF(__pyx_v_encoding);
    __pyx_t_3 = __pyx_v_encoding;
    goto __pyx_L4_bool_binop_done;
  }
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
  __pyx_t_3 = __pyx_v_5pysam_9libcutils_TEXT_ENCODING;
  __pyx_L4_bool_binop_done:;
  __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_errors); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 141, __pyx_L1_error)
  if (!__pyx_t_1) {
  } else {
    __Pyx_INCREF(__pyx_v_errors);
    __pyx_t_5 = __pyx_v_errors;
    goto __pyx_L6_bool_binop_done;
  }
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __pyx_t_5 = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
  __pyx_L6_bool_binop_done:;
  __pyx_t_6 = NULL;
  __pyx_t_7 = 0;
  #if CYTHON_UNPACK_METHODS
  if (likely(PyMethod_Check(__pyx_t_4))) {
    __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_4);
    if (likely(__pyx_t_6)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_4);
      __Pyx_INCREF(__pyx_t_6);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_4, function);
      __pyx_t_7 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[3] = {__pyx_t_6, __pyx_t_3, __pyx_t_5};
    __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_4, __pyx_callargs+1-__pyx_t_7, 2+__pyx_t_7);
    __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
    if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 141, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  }
  __pyx_r = __pyx_t_2;
  __pyx_t_2 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":138
 * 
 * 
 * cdef charptr_to_str(const char* s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_AddTraceback("pysam.libcutils.charptr_to_str", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":144
 * 
 * 
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

static PyObject *__pyx_f_5pysam_9libcutils_charptr_to_str_w_len(char const *__pyx_v_s, size_t __pyx_v_n, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str_w_len *__pyx_optional_args) {
  PyObject *__pyx_v_encoding = ((PyObject *)Py_None);
  PyObject *__pyx_v_errors = ((PyObject *)Py_None);
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("charptr_to_str_w_len", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_encoding = __pyx_optional_args->encoding;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_errors = __pyx_optional_args->errors;
      }
    }
  }

  /* "pysam/libcutils.pyx":145
 * 
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     return s[:n].decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
  __pyx_t_1 = (__pyx_v_s == NULL);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":146
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=None, errors=None):
 *     if s == NULL:
 *         return None             # <<<<<<<<<<<<<<
 *     return s[:n].decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 * 
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":145
 * 
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     return s[:n].decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
  }

  /* "pysam/libcutils.pyx":147
 *     if s == NULL:
 *         return None
 *     return s[:n].decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_3 = __Pyx_PyBytes_FromStringAndSize(__pyx_v_s + 0, __pyx_v_n - 0); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 147, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_t_4 = __Pyx_PyObject_GetAttrStr(__pyx_t_3, __pyx_n_s_decode); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 147, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_encoding); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 147, __pyx_L1_error)
  if (!__pyx_t_1) {
  } else {
    __Pyx_INCREF(__pyx_v_encoding);
    __pyx_t_3 = __pyx_v_encoding;
    goto __pyx_L4_bool_binop_done;
  }
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
  __pyx_t_3 = __pyx_v_5pysam_9libcutils_TEXT_ENCODING;
  __pyx_L4_bool_binop_done:;
  __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_errors); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 147, __pyx_L1_error)
  if (!__pyx_t_1) {
  } else {
    __Pyx_INCREF(__pyx_v_errors);
    __pyx_t_5 = __pyx_v_errors;
    goto __pyx_L6_bool_binop_done;
  }
  __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __pyx_t_5 = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
  __pyx_L6_bool_binop_done:;
  __pyx_t_6 = NULL;
  __pyx_t_7 = 0;
  #if CYTHON_UNPACK_METHODS
  if (likely(PyMethod_Check(__pyx_t_4))) {
    __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_4);
    if (likely(__pyx_t_6)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_4);
      __Pyx_INCREF(__pyx_t_6);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_4, function);
      __pyx_t_7 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[3] = {__pyx_t_6, __pyx_t_3, __pyx_t_5};
    __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_4, __pyx_callargs+1-__pyx_t_7, 2+__pyx_t_7);
    __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
    if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 147, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  }
  __pyx_r = __pyx_t_2;
  __pyx_t_2 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":144
 * 
 * 
 * cdef charptr_to_str_w_len(const char* s, size_t n, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_AddTraceback("pysam.libcutils.charptr_to_str_w_len", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":150
 * 
 * 
 * cdef bytes charptr_to_bytes(const char* s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

static PyObject *__pyx_f_5pysam_9libcutils_charptr_to_bytes(char const *__pyx_v_s, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_bytes *__pyx_optional_args) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("charptr_to_bytes", 0);
  if (__pyx_optional_args) {
  }

  /* "pysam/libcutils.pyx":151
 * 
 * cdef bytes charptr_to_bytes(const char* s, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     else:
 */
  __pyx_t_1 = (__pyx_v_s == NULL);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":152
 * cdef bytes charptr_to_bytes(const char* s, encoding=None, errors=None):
 *     if s == NULL:
 *         return None             # <<<<<<<<<<<<<<
 *     else:
 *         return s
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = ((PyObject*)Py_None); __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":151
 * 
 * cdef bytes charptr_to_bytes(const char* s, encoding=None, errors=None):
 *     if s == NULL:             # <<<<<<<<<<<<<<
 *         return None
 *     else:
 */
  }

  /* "pysam/libcutils.pyx":154
 *         return None
 *     else:
 *         return s             # <<<<<<<<<<<<<<
 * 
 * 
 */
  /*else*/ {
    __Pyx_XDECREF(__pyx_r);
    __pyx_t_2 = __Pyx_PyBytes_FromString(__pyx_v_s); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 154, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __pyx_r = ((PyObject*)__pyx_t_2);
    __pyx_t_2 = 0;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":150
 * 
 * 
 * cdef bytes charptr_to_bytes(const char* s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     if s == NULL:
 *         return None
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_AddTraceback("pysam.libcutils.charptr_to_bytes", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":157
 * 
 * 
 * cdef force_str(object s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """Return s converted to str type of current Python
 *     (bytes in Py2, unicode in Py3)"""
 */

static PyObject *__pyx_f_5pysam_9libcutils_force_str(PyObject *__pyx_v_s, struct __pyx_opt_args_5pysam_9libcutils_force_str *__pyx_optional_args) {
  PyObject *__pyx_v_encoding = ((PyObject *)Py_None);
  PyObject *__pyx_v_errors = ((PyObject *)Py_None);
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("force_str", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_encoding = __pyx_optional_args->encoding;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_errors = __pyx_optional_args->errors;
      }
    }
  }

  /* "pysam/libcutils.pyx":160
 *     """Return s converted to str type of current Python
 *     (bytes in Py2, unicode in Py3)"""
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     if PyBytes_Check(s):
 */
  __pyx_t_1 = (__pyx_v_s == Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":161
 *     (bytes in Py2, unicode in Py3)"""
 *     if s is None:
 *         return None             # <<<<<<<<<<<<<<
 *     if PyBytes_Check(s):
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":160
 *     """Return s converted to str type of current Python
 *     (bytes in Py2, unicode in Py3)"""
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     if PyBytes_Check(s):
 */
  }

  /* "pysam/libcutils.pyx":162
 *     if s is None:
 *         return None
 *     if PyBytes_Check(s):             # <<<<<<<<<<<<<<
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     # assume unicode
 */
  __pyx_t_1 = PyBytes_Check(__pyx_v_s);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":163
 *         return None
 *     if PyBytes_Check(s):
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)             # <<<<<<<<<<<<<<
 *     # assume unicode
 *     return s
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_v_s, __pyx_n_s_decode); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 163, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_encoding); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 163, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_encoding);
      __pyx_t_4 = __pyx_v_encoding;
      goto __pyx_L5_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
    __pyx_t_4 = __pyx_v_5pysam_9libcutils_TEXT_ENCODING;
    __pyx_L5_bool_binop_done:;
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_errors); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 163, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_errors);
      __pyx_t_5 = __pyx_v_errors;
      goto __pyx_L7_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
    __pyx_t_5 = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
    __pyx_L7_bool_binop_done:;
    __pyx_t_6 = NULL;
    __pyx_t_7 = 0;
    #if CYTHON_UNPACK_METHODS
    if (likely(PyMethod_Check(__pyx_t_3))) {
      __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_3);
      if (likely(__pyx_t_6)) {
        PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_3);
        __Pyx_INCREF(__pyx_t_6);
        __Pyx_INCREF(function);
        __Pyx_DECREF_SET(__pyx_t_3, function);
        __pyx_t_7 = 1;
      }
    }
    #endif
    {
      PyObject *__pyx_callargs[3] = {__pyx_t_6, __pyx_t_4, __pyx_t_5};
      __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_3, __pyx_callargs+1-__pyx_t_7, 2+__pyx_t_7);
      __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
      __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
      __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
      if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 163, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    }
    __pyx_r = __pyx_t_2;
    __pyx_t_2 = 0;
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":162
 *     if s is None:
 *         return None
 *     if PyBytes_Check(s):             # <<<<<<<<<<<<<<
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     # assume unicode
 */
  }

  /* "pysam/libcutils.pyx":165
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     # assume unicode
 *     return s             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_s);
  __pyx_r = __pyx_v_s;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":157
 * 
 * 
 * cdef force_str(object s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """Return s converted to str type of current Python
 *     (bytes in Py2, unicode in Py3)"""
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_AddTraceback("pysam.libcutils.force_str", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":168
 * 
 * 
 * cdef decode_bytes(bytes s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """Return s converted to current Python's str type,
 *     always decoding even in Python 2"""
 */

static PyObject *__pyx_f_5pysam_9libcutils_decode_bytes(PyObject *__pyx_v_s, struct __pyx_opt_args_5pysam_9libcutils_decode_bytes *__pyx_optional_args) {
  PyObject *__pyx_v_encoding = ((PyObject *)Py_None);
  PyObject *__pyx_v_errors = ((PyObject *)Py_None);
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int __pyx_t_7;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("decode_bytes", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_encoding = __pyx_optional_args->encoding;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_errors = __pyx_optional_args->errors;
      }
    }
  }

  /* "pysam/libcutils.pyx":171
 *     """Return s converted to current Python's str type,
 *     always decoding even in Python 2"""
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     else:
 */
  __pyx_t_1 = (__pyx_v_s == ((PyObject*)Py_None));
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":172
 *     always decoding even in Python 2"""
 *     if s is None:
 *         return None             # <<<<<<<<<<<<<<
 *     else:
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 */
    __Pyx_XDECREF(__pyx_r);
    __pyx_r = Py_None; __Pyx_INCREF(Py_None);
    goto __pyx_L0;

    /* "pysam/libcutils.pyx":171
 *     """Return s converted to current Python's str type,
 *     always decoding even in Python 2"""
 *     if s is None:             # <<<<<<<<<<<<<<
 *         return None
 *     else:
 */
  }

  /* "pysam/libcutils.pyx":174
 *         return None
 *     else:
 *         return s.decode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  /*else*/ {
    __Pyx_XDECREF(__pyx_r);
    __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_v_s, __pyx_n_s_decode); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 174, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_encoding); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 174, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_encoding);
      __pyx_t_4 = __pyx_v_encoding;
      goto __pyx_L4_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
    __pyx_t_4 = __pyx_v_5pysam_9libcutils_TEXT_ENCODING;
    __pyx_L4_bool_binop_done:;
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_errors); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 174, __pyx_L1_error)
    if (!__pyx_t_1) {
    } else {
      __Pyx_INCREF(__pyx_v_errors);
      __pyx_t_5 = __pyx_v_errors;
      goto __pyx_L6_bool_binop_done;
    }
    __Pyx_INCREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
    __pyx_t_5 = __pyx_v_5pysam_9libcutils_ERROR_HANDLER;
    __pyx_L6_bool_binop_done:;
    __pyx_t_6 = NULL;
    __pyx_t_7 = 0;
    #if CYTHON_UNPACK_METHODS
    if (likely(PyMethod_Check(__pyx_t_3))) {
      __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_3);
      if (likely(__pyx_t_6)) {
        PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_3);
        __Pyx_INCREF(__pyx_t_6);
        __Pyx_INCREF(function);
        __Pyx_DECREF_SET(__pyx_t_3, function);
        __pyx_t_7 = 1;
      }
    }
    #endif
    {
      PyObject *__pyx_callargs[3] = {__pyx_t_6, __pyx_t_4, __pyx_t_5};
      __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_3, __pyx_callargs+1-__pyx_t_7, 2+__pyx_t_7);
      __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
      __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
      __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
      if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 174, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    }
    __pyx_r = __pyx_t_2;
    __pyx_t_2 = 0;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":168
 * 
 * 
 * cdef decode_bytes(bytes s, encoding=None, errors=None):             # <<<<<<<<<<<<<<
 *     """Return s converted to current Python's str type,
 *     always decoding even in Python 2"""
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_AddTraceback("pysam.libcutils.decode_bytes", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":177
 * 
 * 
 * cpdef parse_region(contig=None,             # <<<<<<<<<<<<<<
 *                    start=None,
 *                    stop=None,
 */

static PyObject *__pyx_pw_5pysam_9libcutils_13parse_region(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyObject *__pyx_f_5pysam_9libcutils_parse_region(CYTHON_UNUSED int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_parse_region *__pyx_optional_args) {
  PyObject *__pyx_v_contig = ((PyObject *)Py_None);

  /* "pysam/libcutils.pyx":178
 * 
 * cpdef parse_region(contig=None,
 *                    start=None,             # <<<<<<<<<<<<<<
 *                    stop=None,
 *                    region=None,
 */
  PyObject *__pyx_v_start = ((PyObject *)Py_None);

  /* "pysam/libcutils.pyx":179
 * cpdef parse_region(contig=None,
 *                    start=None,
 *                    stop=None,             # <<<<<<<<<<<<<<
 *                    region=None,
 *                    reference=None,
 */
  PyObject *__pyx_v_stop = ((PyObject *)Py_None);

  /* "pysam/libcutils.pyx":180
 *                    start=None,
 *                    stop=None,
 *                    region=None,             # <<<<<<<<<<<<<<
 *                    reference=None,
 *                    end=None):
 */
  PyObject *__pyx_v_region = ((PyObject *)Py_None);

  /* "pysam/libcutils.pyx":181
 *                    stop=None,
 *                    region=None,
 *                    reference=None,             # <<<<<<<<<<<<<<
 *                    end=None):
 *     """parse alternative ways to specify a genomic region. A region can
 */
  PyObject *__pyx_v_reference = ((PyObject *)Py_None);

  /* "pysam/libcutils.pyx":182
 *                    region=None,
 *                    reference=None,
 *                    end=None):             # <<<<<<<<<<<<<<
 *     """parse alternative ways to specify a genomic region. A region can
 *     either be specified by :term:`reference`, `start` and
 */
  PyObject *__pyx_v_end = ((PyObject *)Py_None);
  int32_t __pyx_v_rstart;
  int32_t __pyx_v_rstop;
  PyObject *__pyx_v_coord = NULL;
  PyObject *__pyx_v_parts = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  PyObject *__pyx_t_2 = NULL;
  int __pyx_t_3;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  int32_t __pyx_t_7;
  int __pyx_t_8;
  PyObject *__pyx_t_9 = NULL;
  PyObject *__pyx_t_10 = NULL;
  PyObject *__pyx_t_11 = NULL;
  PyObject *__pyx_t_12 = NULL;
  PyObject *(*__pyx_t_13)(PyObject *);
  Py_ssize_t __pyx_t_14;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("parse_region", 0);
  if (__pyx_optional_args) {
    if (__pyx_optional_args->__pyx_n > 0) {
      __pyx_v_contig = __pyx_optional_args->contig;
      if (__pyx_optional_args->__pyx_n > 1) {
        __pyx_v_start = __pyx_optional_args->start;
        if (__pyx_optional_args->__pyx_n > 2) {
          __pyx_v_stop = __pyx_optional_args->stop;
          if (__pyx_optional_args->__pyx_n > 3) {
            __pyx_v_region = __pyx_optional_args->region;
            if (__pyx_optional_args->__pyx_n > 4) {
              __pyx_v_reference = __pyx_optional_args->reference;
              if (__pyx_optional_args->__pyx_n > 5) {
                __pyx_v_end = __pyx_optional_args->end;
              }
            }
          }
        }
      }
    }
  }
  __Pyx_INCREF(__pyx_v_contig);
  __Pyx_INCREF(__pyx_v_stop);

  /* "pysam/libcutils.pyx":215
 * 
 * 
 *     if reference is not None:             # <<<<<<<<<<<<<<
 *         if contig is not None:
 *            raise ValueError('contig and reference should not both be specified')
 */
  __pyx_t_1 = (__pyx_v_reference != Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":216
 * 
 *     if reference is not None:
 *         if contig is not None:             # <<<<<<<<<<<<<<
 *            raise ValueError('contig and reference should not both be specified')
 *         contig = reference
 */
    __pyx_t_1 = (__pyx_v_contig != Py_None);
    if (unlikely(__pyx_t_1)) {

      /* "pysam/libcutils.pyx":217
 *     if reference is not None:
 *         if contig is not None:
 *            raise ValueError('contig and reference should not both be specified')             # <<<<<<<<<<<<<<
 *         contig = reference
 * 
 */
      __pyx_t_2 = __Pyx_PyObject_Call(__pyx_builtin_ValueError, __pyx_tuple__3, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 217, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_Raise(__pyx_t_2, 0, 0, 0);
      __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
      __PYX_ERR(0, 217, __pyx_L1_error)

      /* "pysam/libcutils.pyx":216
 * 
 *     if reference is not None:
 *         if contig is not None:             # <<<<<<<<<<<<<<
 *            raise ValueError('contig and reference should not both be specified')
 *         contig = reference
 */
    }

    /* "pysam/libcutils.pyx":218
 *         if contig is not None:
 *            raise ValueError('contig and reference should not both be specified')
 *         contig = reference             # <<<<<<<<<<<<<<
 * 
 *     if contig is not None and region is not None:
 */
    __Pyx_INCREF(__pyx_v_reference);
    __Pyx_DECREF_SET(__pyx_v_contig, __pyx_v_reference);

    /* "pysam/libcutils.pyx":215
 * 
 * 
 *     if reference is not None:             # <<<<<<<<<<<<<<
 *         if contig is not None:
 *            raise ValueError('contig and reference should not both be specified')
 */
  }

  /* "pysam/libcutils.pyx":220
 *         contig = reference
 * 
 *     if contig is not None and region is not None:             # <<<<<<<<<<<<<<
 *         raise ValueError('contig/reference and region should not both be specified')
 * 
 */
  __pyx_t_3 = (__pyx_v_contig != Py_None);
  if (__pyx_t_3) {
  } else {
    __pyx_t_1 = __pyx_t_3;
    goto __pyx_L6_bool_binop_done;
  }
  __pyx_t_3 = (__pyx_v_region != Py_None);
  __pyx_t_1 = __pyx_t_3;
  __pyx_L6_bool_binop_done:;
  if (unlikely(__pyx_t_1)) {

    /* "pysam/libcutils.pyx":221
 * 
 *     if contig is not None and region is not None:
 *         raise ValueError('contig/reference and region should not both be specified')             # <<<<<<<<<<<<<<
 * 
 *     if end is not None:
 */
    __pyx_t_2 = __Pyx_PyObject_Call(__pyx_builtin_ValueError, __pyx_tuple__4, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 221, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_Raise(__pyx_t_2, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __PYX_ERR(0, 221, __pyx_L1_error)

    /* "pysam/libcutils.pyx":220
 *         contig = reference
 * 
 *     if contig is not None and region is not None:             # <<<<<<<<<<<<<<
 *         raise ValueError('contig/reference and region should not both be specified')
 * 
 */
  }

  /* "pysam/libcutils.pyx":223
 *         raise ValueError('contig/reference and region should not both be specified')
 * 
 *     if end is not None:             # <<<<<<<<<<<<<<
 *         if stop is not None:
 *             raise ValueError('stop and end should not both be specified')
 */
  __pyx_t_1 = (__pyx_v_end != Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":224
 * 
 *     if end is not None:
 *         if stop is not None:             # <<<<<<<<<<<<<<
 *             raise ValueError('stop and end should not both be specified')
 *         stop = end
 */
    __pyx_t_1 = (__pyx_v_stop != Py_None);
    if (unlikely(__pyx_t_1)) {

      /* "pysam/libcutils.pyx":225
 *     if end is not None:
 *         if stop is not None:
 *             raise ValueError('stop and end should not both be specified')             # <<<<<<<<<<<<<<
 *         stop = end
 * 
 */
      __pyx_t_2 = __Pyx_PyObject_Call(__pyx_builtin_ValueError, __pyx_tuple__5, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 225, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_Raise(__pyx_t_2, 0, 0, 0);
      __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
      __PYX_ERR(0, 225, __pyx_L1_error)

      /* "pysam/libcutils.pyx":224
 * 
 *     if end is not None:
 *         if stop is not None:             # <<<<<<<<<<<<<<
 *             raise ValueError('stop and end should not both be specified')
 *         stop = end
 */
    }

    /* "pysam/libcutils.pyx":226
 *         if stop is not None:
 *             raise ValueError('stop and end should not both be specified')
 *         stop = end             # <<<<<<<<<<<<<<
 * 
 *     if contig is None and region is None:
 */
    __Pyx_INCREF(__pyx_v_end);
    __Pyx_DECREF_SET(__pyx_v_stop, __pyx_v_end);

    /* "pysam/libcutils.pyx":223
 *         raise ValueError('contig/reference and region should not both be specified')
 * 
 *     if end is not None:             # <<<<<<<<<<<<<<
 *         if stop is not None:
 *             raise ValueError('stop and end should not both be specified')
 */
  }

  /* "pysam/libcutils.pyx":228
 *         stop = end
 * 
 *     if contig is None and region is None:             # <<<<<<<<<<<<<<
 *         raise ValueError("neither contig nor region are given")
 * 
 */
  __pyx_t_3 = (__pyx_v_contig == Py_None);
  if (__pyx_t_3) {
  } else {
    __pyx_t_1 = __pyx_t_3;
    goto __pyx_L11_bool_binop_done;
  }
  __pyx_t_3 = (__pyx_v_region == Py_None);
  __pyx_t_1 = __pyx_t_3;
  __pyx_L11_bool_binop_done:;
  if (unlikely(__pyx_t_1)) {

    /* "pysam/libcutils.pyx":229
 * 
 *     if contig is None and region is None:
 *         raise ValueError("neither contig nor region are given")             # <<<<<<<<<<<<<<
 * 
 *     rstart = 0
 */
    __pyx_t_2 = __Pyx_PyObject_Call(__pyx_builtin_ValueError, __pyx_tuple__6, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 229, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_Raise(__pyx_t_2, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __PYX_ERR(0, 229, __pyx_L1_error)

    /* "pysam/libcutils.pyx":228
 *         stop = end
 * 
 *     if contig is None and region is None:             # <<<<<<<<<<<<<<
 *         raise ValueError("neither contig nor region are given")
 * 
 */
  }

  /* "pysam/libcutils.pyx":231
 *         raise ValueError("neither contig nor region are given")
 * 
 *     rstart = 0             # <<<<<<<<<<<<<<
 *     rstop = MAX_POS
 *     if start is not None:
 */
  __pyx_v_rstart = 0;

  /* "pysam/libcutils.pyx":232
 * 
 *     rstart = 0
 *     rstop = MAX_POS             # <<<<<<<<<<<<<<
 *     if start is not None:
 *         try:
 */
  __pyx_v_rstop = __pyx_v_5pysam_9libcutils_MAX_POS;

  /* "pysam/libcutils.pyx":233
 *     rstart = 0
 *     rstop = MAX_POS
 *     if start is not None:             # <<<<<<<<<<<<<<
 *         try:
 *             rstart = start
 */
  __pyx_t_1 = (__pyx_v_start != Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":234
 *     rstop = MAX_POS
 *     if start is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstart = start
 *         except OverflowError:
 */
    {
      __Pyx_PyThreadState_declare
      __Pyx_PyThreadState_assign
      __Pyx_ExceptionSave(&__pyx_t_4, &__pyx_t_5, &__pyx_t_6);
      __Pyx_XGOTREF(__pyx_t_4);
      __Pyx_XGOTREF(__pyx_t_5);
      __Pyx_XGOTREF(__pyx_t_6);
      /*try:*/ {

        /* "pysam/libcutils.pyx":235
 *     if start is not None:
 *         try:
 *             rstart = start             # <<<<<<<<<<<<<<
 *         except OverflowError:
 *             raise ValueError('start out of range (%i)' % start)
 */
        __pyx_t_7 = __Pyx_PyInt_As_int32_t(__pyx_v_start); if (unlikely((__pyx_t_7 == ((int32_t)-1)) && PyErr_Occurred())) __PYX_ERR(0, 235, __pyx_L14_error)
        __pyx_v_rstart = __pyx_t_7;

        /* "pysam/libcutils.pyx":234
 *     rstop = MAX_POS
 *     if start is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstart = start
 *         except OverflowError:
 */
      }
      __Pyx_XDECREF(__pyx_t_4); __pyx_t_4 = 0;
      __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
      __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
      goto __pyx_L19_try_end;
      __pyx_L14_error:;
      __Pyx_XDECREF(__pyx_t_2); __pyx_t_2 = 0;

      /* "pysam/libcutils.pyx":236
 *         try:
 *             rstart = start
 *         except OverflowError:             # <<<<<<<<<<<<<<
 *             raise ValueError('start out of range (%i)' % start)
 * 
 */
      __pyx_t_8 = __Pyx_PyErr_ExceptionMatches(__pyx_builtin_OverflowError);
      if (__pyx_t_8) {
        __Pyx_AddTraceback("pysam.libcutils.parse_region", __pyx_clineno, __pyx_lineno, __pyx_filename);
        if (__Pyx_GetException(&__pyx_t_2, &__pyx_t_9, &__pyx_t_10) < 0) __PYX_ERR(0, 236, __pyx_L16_except_error)
        __Pyx_XGOTREF(__pyx_t_2);
        __Pyx_XGOTREF(__pyx_t_9);
        __Pyx_XGOTREF(__pyx_t_10);

        /* "pysam/libcutils.pyx":237
 *             rstart = start
 *         except OverflowError:
 *             raise ValueError('start out of range (%i)' % start)             # <<<<<<<<<<<<<<
 * 
 *     if stop is not None:
 */
        __pyx_t_11 = __Pyx_PyUnicode_FormatSafe(__pyx_kp_u_start_out_of_range_i, __pyx_v_start); if (unlikely(!__pyx_t_11)) __PYX_ERR(0, 237, __pyx_L16_except_error)
        __Pyx_GOTREF(__pyx_t_11);
        __pyx_t_12 = __Pyx_PyObject_CallOneArg(__pyx_builtin_ValueError, __pyx_t_11); if (unlikely(!__pyx_t_12)) __PYX_ERR(0, 237, __pyx_L16_except_error)
        __Pyx_GOTREF(__pyx_t_12);
        __Pyx_DECREF(__pyx_t_11); __pyx_t_11 = 0;
        __Pyx_Raise(__pyx_t_12, 0, 0, 0);
        __Pyx_DECREF(__pyx_t_12); __pyx_t_12 = 0;
        __PYX_ERR(0, 237, __pyx_L16_except_error)
      }
      goto __pyx_L16_except_error;

      /* "pysam/libcutils.pyx":234
 *     rstop = MAX_POS
 *     if start is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstart = start
 *         except OverflowError:
 */
      __pyx_L16_except_error:;
      __Pyx_XGIVEREF(__pyx_t_4);
      __Pyx_XGIVEREF(__pyx_t_5);
      __Pyx_XGIVEREF(__pyx_t_6);
      __Pyx_ExceptionReset(__pyx_t_4, __pyx_t_5, __pyx_t_6);
      goto __pyx_L1_error;
      __pyx_L19_try_end:;
    }

    /* "pysam/libcutils.pyx":233
 *     rstart = 0
 *     rstop = MAX_POS
 *     if start is not None:             # <<<<<<<<<<<<<<
 *         try:
 *             rstart = start
 */
  }

  /* "pysam/libcutils.pyx":239
 *             raise ValueError('start out of range (%i)' % start)
 * 
 *     if stop is not None:             # <<<<<<<<<<<<<<
 *         try:
 *             rstop = stop
 */
  __pyx_t_1 = (__pyx_v_stop != Py_None);
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":240
 * 
 *     if stop is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstop = stop
 *         except OverflowError:
 */
    {
      __Pyx_PyThreadState_declare
      __Pyx_PyThreadState_assign
      __Pyx_ExceptionSave(&__pyx_t_6, &__pyx_t_5, &__pyx_t_4);
      __Pyx_XGOTREF(__pyx_t_6);
      __Pyx_XGOTREF(__pyx_t_5);
      __Pyx_XGOTREF(__pyx_t_4);
      /*try:*/ {

        /* "pysam/libcutils.pyx":241
 *     if stop is not None:
 *         try:
 *             rstop = stop             # <<<<<<<<<<<<<<
 *         except OverflowError:
 *             raise ValueError('stop out of range (%i)' % stop)
 */
        __pyx_t_7 = __Pyx_PyInt_As_int32_t(__pyx_v_stop); if (unlikely((__pyx_t_7 == ((int32_t)-1)) && PyErr_Occurred())) __PYX_ERR(0, 241, __pyx_L23_error)
        __pyx_v_rstop = __pyx_t_7;

        /* "pysam/libcutils.pyx":240
 * 
 *     if stop is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstop = stop
 *         except OverflowError:
 */
      }
      __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
      __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
      __Pyx_XDECREF(__pyx_t_4); __pyx_t_4 = 0;
      goto __pyx_L28_try_end;
      __pyx_L23_error:;
      __Pyx_XDECREF(__pyx_t_10); __pyx_t_10 = 0;
      __Pyx_XDECREF(__pyx_t_11); __pyx_t_11 = 0;
      __Pyx_XDECREF(__pyx_t_12); __pyx_t_12 = 0;
      __Pyx_XDECREF(__pyx_t_2); __pyx_t_2 = 0;
      __Pyx_XDECREF(__pyx_t_9); __pyx_t_9 = 0;

      /* "pysam/libcutils.pyx":242
 *         try:
 *             rstop = stop
 *         except OverflowError:             # <<<<<<<<<<<<<<
 *             raise ValueError('stop out of range (%i)' % stop)
 * 
 */
      __pyx_t_8 = __Pyx_PyErr_ExceptionMatches(__pyx_builtin_OverflowError);
      if (__pyx_t_8) {
        __Pyx_AddTraceback("pysam.libcutils.parse_region", __pyx_clineno, __pyx_lineno, __pyx_filename);
        if (__Pyx_GetException(&__pyx_t_10, &__pyx_t_9, &__pyx_t_2) < 0) __PYX_ERR(0, 242, __pyx_L25_except_error)
        __Pyx_XGOTREF(__pyx_t_10);
        __Pyx_XGOTREF(__pyx_t_9);
        __Pyx_XGOTREF(__pyx_t_2);

        /* "pysam/libcutils.pyx":243
 *             rstop = stop
 *         except OverflowError:
 *             raise ValueError('stop out of range (%i)' % stop)             # <<<<<<<<<<<<<<
 * 
 *     if region:
 */
        __pyx_t_12 = __Pyx_PyUnicode_FormatSafe(__pyx_kp_u_stop_out_of_range_i, __pyx_v_stop); if (unlikely(!__pyx_t_12)) __PYX_ERR(0, 243, __pyx_L25_except_error)
        __Pyx_GOTREF(__pyx_t_12);
        __pyx_t_11 = __Pyx_PyObject_CallOneArg(__pyx_builtin_ValueError, __pyx_t_12); if (unlikely(!__pyx_t_11)) __PYX_ERR(0, 243, __pyx_L25_except_error)
        __Pyx_GOTREF(__pyx_t_11);
        __Pyx_DECREF(__pyx_t_12); __pyx_t_12 = 0;
        __Pyx_Raise(__pyx_t_11, 0, 0, 0);
        __Pyx_DECREF(__pyx_t_11); __pyx_t_11 = 0;
        __PYX_ERR(0, 243, __pyx_L25_except_error)
      }
      goto __pyx_L25_except_error;

      /* "pysam/libcutils.pyx":240
 * 
 *     if stop is not None:
 *         try:             # <<<<<<<<<<<<<<
 *             rstop = stop
 *         except OverflowError:
 */
      __pyx_L25_except_error:;
      __Pyx_XGIVEREF(__pyx_t_6);
      __Pyx_XGIVEREF(__pyx_t_5);
      __Pyx_XGIVEREF(__pyx_t_4);
      __Pyx_ExceptionReset(__pyx_t_6, __pyx_t_5, __pyx_t_4);
      goto __pyx_L1_error;
      __pyx_L28_try_end:;
    }

    /* "pysam/libcutils.pyx":239
 *             raise ValueError('start out of range (%i)' % start)
 * 
 *     if stop is not None:             # <<<<<<<<<<<<<<
 *         try:
 *             rstop = stop
 */
  }

  /* "pysam/libcutils.pyx":245
 *             raise ValueError('stop out of range (%i)' % stop)
 * 
 *     if region:             # <<<<<<<<<<<<<<
 *         if ":" in region:
 *             contig, coord = region.split(":")
 */
  __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_region); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 245, __pyx_L1_error)
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":246
 * 
 *     if region:
 *         if ":" in region:             # <<<<<<<<<<<<<<
 *             contig, coord = region.split(":")
 *             parts = coord.split("-")
 */
    __pyx_t_1 = (__Pyx_PySequence_ContainsTF(__pyx_kp_u__7, __pyx_v_region, Py_EQ)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 246, __pyx_L1_error)
    if (__pyx_t_1) {

      /* "pysam/libcutils.pyx":247
 *     if region:
 *         if ":" in region:
 *             contig, coord = region.split(":")             # <<<<<<<<<<<<<<
 *             parts = coord.split("-")
 *             rstart = int(parts[0]) - 1
 */
      __pyx_t_9 = __Pyx_PyObject_GetAttrStr(__pyx_v_region, __pyx_n_s_split); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 247, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_9);
      __pyx_t_10 = NULL;
      __pyx_t_8 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_9))) {
        __pyx_t_10 = PyMethod_GET_SELF(__pyx_t_9);
        if (likely(__pyx_t_10)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_9);
          __Pyx_INCREF(__pyx_t_10);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_9, function);
          __pyx_t_8 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_10, __pyx_kp_u__7};
        __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_9, __pyx_callargs+1-__pyx_t_8, 1+__pyx_t_8);
        __Pyx_XDECREF(__pyx_t_10); __pyx_t_10 = 0;
        if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 247, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_2);
        __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
      }
      if ((likely(PyTuple_CheckExact(__pyx_t_2))) || (PyList_CheckExact(__pyx_t_2))) {
        PyObject* sequence = __pyx_t_2;
        Py_ssize_t size = __Pyx_PySequence_SIZE(sequence);
        if (unlikely(size != 2)) {
          if (size > 2) __Pyx_RaiseTooManyValuesError(2);
          else if (size >= 0) __Pyx_RaiseNeedMoreValuesError(size);
          __PYX_ERR(0, 247, __pyx_L1_error)
        }
        #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
        if (likely(PyTuple_CheckExact(sequence))) {
          __pyx_t_9 = PyTuple_GET_ITEM(sequence, 0); 
          __pyx_t_10 = PyTuple_GET_ITEM(sequence, 1); 
        } else {
          __pyx_t_9 = PyList_GET_ITEM(sequence, 0); 
          __pyx_t_10 = PyList_GET_ITEM(sequence, 1); 
        }
        __Pyx_INCREF(__pyx_t_9);
        __Pyx_INCREF(__pyx_t_10);
        #else
        __pyx_t_9 = PySequence_ITEM(sequence, 0); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 247, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_9);
        __pyx_t_10 = PySequence_ITEM(sequence, 1); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 247, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_10);
        #endif
        __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
      } else {
        Py_ssize_t index = -1;
        __pyx_t_11 = PyObject_GetIter(__pyx_t_2); if (unlikely(!__pyx_t_11)) __PYX_ERR(0, 247, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_11);
        __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
        __pyx_t_13 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_11);
        index = 0; __pyx_t_9 = __pyx_t_13(__pyx_t_11); if (unlikely(!__pyx_t_9)) goto __pyx_L33_unpacking_failed;
        __Pyx_GOTREF(__pyx_t_9);
        index = 1; __pyx_t_10 = __pyx_t_13(__pyx_t_11); if (unlikely(!__pyx_t_10)) goto __pyx_L33_unpacking_failed;
        __Pyx_GOTREF(__pyx_t_10);
        if (__Pyx_IternextUnpackEndCheck(__pyx_t_13(__pyx_t_11), 2) < 0) __PYX_ERR(0, 247, __pyx_L1_error)
        __pyx_t_13 = NULL;
        __Pyx_DECREF(__pyx_t_11); __pyx_t_11 = 0;
        goto __pyx_L34_unpacking_done;
        __pyx_L33_unpacking_failed:;
        __Pyx_DECREF(__pyx_t_11); __pyx_t_11 = 0;
        __pyx_t_13 = NULL;
        if (__Pyx_IterFinish() == 0) __Pyx_RaiseNeedMoreValuesError(index);
        __PYX_ERR(0, 247, __pyx_L1_error)
        __pyx_L34_unpacking_done:;
      }
      __Pyx_DECREF_SET(__pyx_v_contig, __pyx_t_9);
      __pyx_t_9 = 0;
      __pyx_v_coord = __pyx_t_10;
      __pyx_t_10 = 0;

      /* "pysam/libcutils.pyx":248
 *         if ":" in region:
 *             contig, coord = region.split(":")
 *             parts = coord.split("-")             # <<<<<<<<<<<<<<
 *             rstart = int(parts[0]) - 1
 *             if len(parts) >= 1:
 */
      __pyx_t_10 = __Pyx_PyObject_GetAttrStr(__pyx_v_coord, __pyx_n_s_split); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 248, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_10);
      __pyx_t_9 = NULL;
      __pyx_t_8 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_10))) {
        __pyx_t_9 = PyMethod_GET_SELF(__pyx_t_10);
        if (likely(__pyx_t_9)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_10);
          __Pyx_INCREF(__pyx_t_9);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_10, function);
          __pyx_t_8 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_9, __pyx_kp_u__8};
        __pyx_t_2 = __Pyx_PyObject_FastCall(__pyx_t_10, __pyx_callargs+1-__pyx_t_8, 1+__pyx_t_8);
        __Pyx_XDECREF(__pyx_t_9); __pyx_t_9 = 0;
        if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 248, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_2);
        __Pyx_DECREF(__pyx_t_10); __pyx_t_10 = 0;
      }
      __pyx_v_parts = __pyx_t_2;
      __pyx_t_2 = 0;

      /* "pysam/libcutils.pyx":249
 *             contig, coord = region.split(":")
 *             parts = coord.split("-")
 *             rstart = int(parts[0]) - 1             # <<<<<<<<<<<<<<
 *             if len(parts) >= 1:
 *                 rstop = int(parts[1])
 */
      __pyx_t_2 = __Pyx_GetItemInt(__pyx_v_parts, 0, long, 1, __Pyx_PyInt_From_long, 0, 0, 1); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 249, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __pyx_t_10 = __Pyx_PyNumber_Int(__pyx_t_2); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 249, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_10);
      __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
      __pyx_t_2 = __Pyx_PyInt_SubtractObjC(__pyx_t_10, __pyx_int_1, 1, 0, 0); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 249, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_2);
      __Pyx_DECREF(__pyx_t_10); __pyx_t_10 = 0;
      __pyx_t_7 = __Pyx_PyInt_As_int32_t(__pyx_t_2); if (unlikely((__pyx_t_7 == ((int32_t)-1)) && PyErr_Occurred())) __PYX_ERR(0, 249, __pyx_L1_error)
      __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
      __pyx_v_rstart = __pyx_t_7;

      /* "pysam/libcutils.pyx":250
 *             parts = coord.split("-")
 *             rstart = int(parts[0]) - 1
 *             if len(parts) >= 1:             # <<<<<<<<<<<<<<
 *                 rstop = int(parts[1])
 *         else:
 */
      __pyx_t_14 = PyObject_Length(__pyx_v_parts); if (unlikely(__pyx_t_14 == ((Py_ssize_t)-1))) __PYX_ERR(0, 250, __pyx_L1_error)
      __pyx_t_1 = (__pyx_t_14 >= 1);
      if (__pyx_t_1) {

        /* "pysam/libcutils.pyx":251
 *             rstart = int(parts[0]) - 1
 *             if len(parts) >= 1:
 *                 rstop = int(parts[1])             # <<<<<<<<<<<<<<
 *         else:
 *             contig = region
 */
        __pyx_t_2 = __Pyx_GetItemInt(__pyx_v_parts, 1, long, 1, __Pyx_PyInt_From_long, 0, 0, 1); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 251, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_2);
        __pyx_t_10 = __Pyx_PyNumber_Int(__pyx_t_2); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 251, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_10);
        __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
        __pyx_t_7 = __Pyx_PyInt_As_int32_t(__pyx_t_10); if (unlikely((__pyx_t_7 == ((int32_t)-1)) && PyErr_Occurred())) __PYX_ERR(0, 251, __pyx_L1_error)
        __Pyx_DECREF(__pyx_t_10); __pyx_t_10 = 0;
        __pyx_v_rstop = __pyx_t_7;

        /* "pysam/libcutils.pyx":250
 *             parts = coord.split("-")
 *             rstart = int(parts[0]) - 1
 *             if len(parts) >= 1:             # <<<<<<<<<<<<<<
 *                 rstop = int(parts[1])
 *         else:
 */
      }

      /* "pysam/libcutils.pyx":246
 * 
 *     if region:
 *         if ":" in region:             # <<<<<<<<<<<<<<
 *             contig, coord = region.split(":")
 *             parts = coord.split("-")
 */
      goto __pyx_L32;
    }

    /* "pysam/libcutils.pyx":253
 *                 rstop = int(parts[1])
 *         else:
 *             contig = region             # <<<<<<<<<<<<<<
 * 
 *     if rstart > rstop:
 */
    /*else*/ {
      __Pyx_INCREF(__pyx_v_region);
      __Pyx_DECREF_SET(__pyx_v_contig, __pyx_v_region);
    }
    __pyx_L32:;

    /* "pysam/libcutils.pyx":245
 *             raise ValueError('stop out of range (%i)' % stop)
 * 
 *     if region:             # <<<<<<<<<<<<<<
 *         if ":" in region:
 *             contig, coord = region.split(":")
 */
  }

  /* "pysam/libcutils.pyx":255
 *             contig = region
 * 
 *     if rstart > rstop:             # <<<<<<<<<<<<<<
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))
 *     if not 0 <= rstart < MAX_POS:
 */
  __pyx_t_1 = (__pyx_v_rstart > __pyx_v_rstop);
  if (unlikely(__pyx_t_1)) {

    /* "pysam/libcutils.pyx":256
 * 
 *     if rstart > rstop:
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))             # <<<<<<<<<<<<<<
 *     if not 0 <= rstart < MAX_POS:
 *         raise ValueError('start out of range (%i)' % rstart)
 */
    __pyx_t_10 = __Pyx_PyInt_From_int32_t(__pyx_v_rstart); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 256, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_10);
    __pyx_t_2 = __Pyx_PyInt_From_int32_t(__pyx_v_rstop); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 256, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __pyx_t_9 = PyTuple_New(2); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 256, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __Pyx_GIVEREF(__pyx_t_10);
    if (__Pyx_PyTuple_SET_ITEM(__pyx_t_9, 0, __pyx_t_10)) __PYX_ERR(0, 256, __pyx_L1_error);
    __Pyx_GIVEREF(__pyx_t_2);
    if (__Pyx_PyTuple_SET_ITEM(__pyx_t_9, 1, __pyx_t_2)) __PYX_ERR(0, 256, __pyx_L1_error);
    __pyx_t_10 = 0;
    __pyx_t_2 = 0;
    __pyx_t_2 = PyUnicode_Format(__pyx_kp_u_invalid_coordinates_start_i_stop, __pyx_t_9); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 256, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __pyx_t_9 = __Pyx_PyObject_CallOneArg(__pyx_builtin_ValueError, __pyx_t_2); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 256, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __Pyx_Raise(__pyx_t_9, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __PYX_ERR(0, 256, __pyx_L1_error)

    /* "pysam/libcutils.pyx":255
 *             contig = region
 * 
 *     if rstart > rstop:             # <<<<<<<<<<<<<<
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))
 *     if not 0 <= rstart < MAX_POS:
 */
  }

  /* "pysam/libcutils.pyx":257
 *     if rstart > rstop:
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))
 *     if not 0 <= rstart < MAX_POS:             # <<<<<<<<<<<<<<
 *         raise ValueError('start out of range (%i)' % rstart)
 *     if not 0 <= rstop <= MAX_POS:
 */
  __pyx_t_1 = (0 <= __pyx_v_rstart);
  if (__pyx_t_1) {
    __pyx_t_1 = (__pyx_v_rstart < __pyx_v_5pysam_9libcutils_MAX_POS);
  }
  __pyx_t_3 = (!__pyx_t_1);
  if (unlikely(__pyx_t_3)) {

    /* "pysam/libcutils.pyx":258
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))
 *     if not 0 <= rstart < MAX_POS:
 *         raise ValueError('start out of range (%i)' % rstart)             # <<<<<<<<<<<<<<
 *     if not 0 <= rstop <= MAX_POS:
 *         raise ValueError('stop out of range (%i)' % rstop)
 */
    __pyx_t_9 = __Pyx_PyInt_From_int32_t(__pyx_v_rstart); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 258, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __pyx_t_2 = PyUnicode_Format(__pyx_kp_u_start_out_of_range_i, __pyx_t_9); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 258, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __pyx_t_9 = __Pyx_PyObject_CallOneArg(__pyx_builtin_ValueError, __pyx_t_2); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 258, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __Pyx_Raise(__pyx_t_9, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __PYX_ERR(0, 258, __pyx_L1_error)

    /* "pysam/libcutils.pyx":257
 *     if rstart > rstop:
 *         raise ValueError('invalid coordinates: start (%i) > stop (%i)' % (rstart, rstop))
 *     if not 0 <= rstart < MAX_POS:             # <<<<<<<<<<<<<<
 *         raise ValueError('start out of range (%i)' % rstart)
 *     if not 0 <= rstop <= MAX_POS:
 */
  }

  /* "pysam/libcutils.pyx":259
 *     if not 0 <= rstart < MAX_POS:
 *         raise ValueError('start out of range (%i)' % rstart)
 *     if not 0 <= rstop <= MAX_POS:             # <<<<<<<<<<<<<<
 *         raise ValueError('stop out of range (%i)' % rstop)
 * 
 */
  __pyx_t_3 = (0 <= __pyx_v_rstop);
  if (__pyx_t_3) {
    __pyx_t_3 = (__pyx_v_rstop <= __pyx_v_5pysam_9libcutils_MAX_POS);
  }
  __pyx_t_1 = (!__pyx_t_3);
  if (unlikely(__pyx_t_1)) {

    /* "pysam/libcutils.pyx":260
 *         raise ValueError('start out of range (%i)' % rstart)
 *     if not 0 <= rstop <= MAX_POS:
 *         raise ValueError('stop out of range (%i)' % rstop)             # <<<<<<<<<<<<<<
 * 
 *     return contig, rstart, rstop
 */
    __pyx_t_9 = __Pyx_PyInt_From_int32_t(__pyx_v_rstop); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 260, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __pyx_t_2 = PyUnicode_Format(__pyx_kp_u_stop_out_of_range_i, __pyx_t_9); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 260, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_2);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __pyx_t_9 = __Pyx_PyObject_CallOneArg(__pyx_builtin_ValueError, __pyx_t_2); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 260, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_9);
    __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
    __Pyx_Raise(__pyx_t_9, 0, 0, 0);
    __Pyx_DECREF(__pyx_t_9); __pyx_t_9 = 0;
    __PYX_ERR(0, 260, __pyx_L1_error)

    /* "pysam/libcutils.pyx":259
 *     if not 0 <= rstart < MAX_POS:
 *         raise ValueError('start out of range (%i)' % rstart)
 *     if not 0 <= rstop <= MAX_POS:             # <<<<<<<<<<<<<<
 *         raise ValueError('stop out of range (%i)' % rstop)
 * 
 */
  }

  /* "pysam/libcutils.pyx":262
 *         raise ValueError('stop out of range (%i)' % rstop)
 * 
 *     return contig, rstart, rstop             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_9 = __Pyx_PyInt_From_int32_t(__pyx_v_rstart); if (unlikely(!__pyx_t_9)) __PYX_ERR(0, 262, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_9);
  __pyx_t_2 = __Pyx_PyInt_From_int32_t(__pyx_v_rstop); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 262, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __pyx_t_10 = PyTuple_New(3); if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 262, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_10);
  __Pyx_INCREF(__pyx_v_contig);
  __Pyx_GIVEREF(__pyx_v_contig);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_10, 0, __pyx_v_contig)) __PYX_ERR(0, 262, __pyx_L1_error);
  __Pyx_GIVEREF(__pyx_t_9);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_10, 1, __pyx_t_9)) __PYX_ERR(0, 262, __pyx_L1_error);
  __Pyx_GIVEREF(__pyx_t_2);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_10, 2, __pyx_t_2)) __PYX_ERR(0, 262, __pyx_L1_error);
  __pyx_t_9 = 0;
  __pyx_t_2 = 0;
  __pyx_r = __pyx_t_10;
  __pyx_t_10 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":177
 * 
 * 
 * cpdef parse_region(contig=None,             # <<<<<<<<<<<<<<
 *                    start=None,
 *                    stop=None,
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_9);
  __Pyx_XDECREF(__pyx_t_10);
  __Pyx_XDECREF(__pyx_t_11);
  __Pyx_XDECREF(__pyx_t_12);
  __Pyx_AddTraceback("pysam.libcutils.parse_region", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = 0;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_coord);
  __Pyx_XDECREF(__pyx_v_parts);
  __Pyx_XDECREF(__pyx_v_contig);
  __Pyx_XDECREF(__pyx_v_stop);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_13parse_region(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
PyDoc_STRVAR(__pyx_doc_5pysam_9libcutils_12parse_region, "parse alternative ways to specify a genomic region. A region can\n    either be specified by :term:`reference`, `start` and\n    `end`. `start` and `end` denote 0-based, half-open intervals.\n    \n    :term:`reference` and `end` are also accepted for backward\n    compatibility as synonyms for :term:`contig` and `stop`,\n    respectively.\n\n    Alternatively, a samtools :term:`region` string can be supplied.\n\n    If any of the coordinates are missing they will be replaced by the\n    minimum (`start`) or maximum (`end`) coordinate.\n\n    Note that region strings are 1-based, while `start` and `end`\n    denote an interval in python coordinates.\n\n    Returns\n    -------\n\n    tuple :  a tuple of `reference`, `start` and `end`.\n\n    Raises\n    ------\n\n    ValueError\n       for invalid or out of bounds regions.\n\n    ");
static PyMethodDef __pyx_mdef_5pysam_9libcutils_13parse_region = {"parse_region", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_13parse_region, __Pyx_METH_FASTCALL|METH_KEYWORDS, __pyx_doc_5pysam_9libcutils_12parse_region};
static PyObject *__pyx_pw_5pysam_9libcutils_13parse_region(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_contig = 0;
  PyObject *__pyx_v_start = 0;
  PyObject *__pyx_v_stop = 0;
  PyObject *__pyx_v_region = 0;
  PyObject *__pyx_v_reference = 0;
  PyObject *__pyx_v_end = 0;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[6] = {0,0,0,0,0,0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("parse_region (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 177, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_contig,&__pyx_n_s_start,&__pyx_n_s_stop,&__pyx_n_s_region,&__pyx_n_s_reference,&__pyx_n_s_end,0};
    values[0] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":178
 * 
 * cpdef parse_region(contig=None,
 *                    start=None,             # <<<<<<<<<<<<<<
 *                    stop=None,
 *                    region=None,
 */
    values[1] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":179
 * cpdef parse_region(contig=None,
 *                    start=None,
 *                    stop=None,             # <<<<<<<<<<<<<<
 *                    region=None,
 *                    reference=None,
 */
    values[2] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":180
 *                    start=None,
 *                    stop=None,
 *                    region=None,             # <<<<<<<<<<<<<<
 *                    reference=None,
 *                    end=None):
 */
    values[3] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":181
 *                    stop=None,
 *                    region=None,
 *                    reference=None,             # <<<<<<<<<<<<<<
 *                    end=None):
 *     """parse alternative ways to specify a genomic region. A region can
 */
    values[4] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":182
 *                    region=None,
 *                    reference=None,
 *                    end=None):             # <<<<<<<<<<<<<<
 *     """parse alternative ways to specify a genomic region. A region can
 *     either be specified by :term:`reference`, `start` and
 */
    values[5] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  6: values[5] = __Pyx_Arg_FASTCALL(__pyx_args, 5);
        CYTHON_FALLTHROUGH;
        case  5: values[4] = __Pyx_Arg_FASTCALL(__pyx_args, 4);
        CYTHON_FALLTHROUGH;
        case  4: values[3] = __Pyx_Arg_FASTCALL(__pyx_args, 3);
        CYTHON_FALLTHROUGH;
        case  3: values[2] = __Pyx_Arg_FASTCALL(__pyx_args, 2);
        CYTHON_FALLTHROUGH;
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_contig);
          if (value) { values[0] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  1:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_start);
          if (value) { values[1] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  2:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_stop);
          if (value) { values[2] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  3:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_region);
          if (value) { values[3] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  4:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_reference);
          if (value) { values[4] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  5:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_end);
          if (value) { values[5] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 177, __pyx_L3_error)
        }
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "parse_region") < 0)) __PYX_ERR(0, 177, __pyx_L3_error)
      }
    } else {
      switch (__pyx_nargs) {
        case  6: values[5] = __Pyx_Arg_FASTCALL(__pyx_args, 5);
        CYTHON_FALLTHROUGH;
        case  5: values[4] = __Pyx_Arg_FASTCALL(__pyx_args, 4);
        CYTHON_FALLTHROUGH;
        case  4: values[3] = __Pyx_Arg_FASTCALL(__pyx_args, 3);
        CYTHON_FALLTHROUGH;
        case  3: values[2] = __Pyx_Arg_FASTCALL(__pyx_args, 2);
        CYTHON_FALLTHROUGH;
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
    }
    __pyx_v_contig = values[0];
    __pyx_v_start = values[1];
    __pyx_v_stop = values[2];
    __pyx_v_region = values[3];
    __pyx_v_reference = values[4];
    __pyx_v_end = values[5];
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("parse_region", 0, 0, 6, __pyx_nargs); __PYX_ERR(0, 177, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils.parse_region", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_12parse_region(__pyx_self, __pyx_v_contig, __pyx_v_start, __pyx_v_stop, __pyx_v_region, __pyx_v_reference, __pyx_v_end);

  /* "pysam/libcutils.pyx":177
 * 
 * 
 * cpdef parse_region(contig=None,             # <<<<<<<<<<<<<<
 *                    start=None,
 *                    stop=None,
 */

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_12parse_region(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_contig, PyObject *__pyx_v_start, PyObject *__pyx_v_stop, PyObject *__pyx_v_region, PyObject *__pyx_v_reference, PyObject *__pyx_v_end) {
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  struct __pyx_opt_args_5pysam_9libcutils_parse_region __pyx_t_2;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("parse_region", 0);
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_2.__pyx_n = 6;
  __pyx_t_2.contig = __pyx_v_contig;
  __pyx_t_2.start = __pyx_v_start;
  __pyx_t_2.stop = __pyx_v_stop;
  __pyx_t_2.region = __pyx_v_region;
  __pyx_t_2.reference = __pyx_v_reference;
  __pyx_t_2.end = __pyx_v_end;
  __pyx_t_1 = __pyx_f_5pysam_9libcutils_parse_region(0, &__pyx_t_2); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 177, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_r = __pyx_t_1;
  __pyx_t_1 = 0;
  goto __pyx_L0;

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_AddTraceback("pysam.libcutils.parse_region", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":265
 * 
 * 
 * cdef int libc_whence_from_io(int whence):             # <<<<<<<<<<<<<<
 *     # io.SEEK_SET/_CUR/_END are by definition 0/1/2 but C/POSIX's equivalents
 *     # have unspecified values. So we must translate, but checking for 0/1/2
 */

static int __pyx_f_5pysam_9libcutils_libc_whence_from_io(int __pyx_v_whence) {
  int __pyx_r;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  __Pyx_RefNannySetupContext("libc_whence_from_io", 0);

  /* "pysam/libcutils.pyx":269
 *     # have unspecified values. So we must translate, but checking for 0/1/2
 *     # rather than io.SEEK_SET/etc suffices.
 *     if whence == 0: return SEEK_SET             # <<<<<<<<<<<<<<
 *     if whence == 1: return SEEK_CUR
 *     if whence == 2: return SEEK_END
 */
  __pyx_t_1 = (__pyx_v_whence == 0);
  if (__pyx_t_1) {
    __pyx_r = SEEK_SET;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":270
 *     # rather than io.SEEK_SET/etc suffices.
 *     if whence == 0: return SEEK_SET
 *     if whence == 1: return SEEK_CUR             # <<<<<<<<<<<<<<
 *     if whence == 2: return SEEK_END
 *     return whence  # Otherwise likely invalid, but let HTSlib or OS report it
 */
  __pyx_t_1 = (__pyx_v_whence == 1);
  if (__pyx_t_1) {
    __pyx_r = SEEK_CUR;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":271
 *     if whence == 0: return SEEK_SET
 *     if whence == 1: return SEEK_CUR
 *     if whence == 2: return SEEK_END             # <<<<<<<<<<<<<<
 *     return whence  # Otherwise likely invalid, but let HTSlib or OS report it
 * 
 */
  __pyx_t_1 = (__pyx_v_whence == 2);
  if (__pyx_t_1) {
    __pyx_r = SEEK_END;
    goto __pyx_L0;
  }

  /* "pysam/libcutils.pyx":272
 *     if whence == 1: return SEEK_CUR
 *     if whence == 2: return SEEK_END
 *     return whence  # Otherwise likely invalid, but let HTSlib or OS report it             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __pyx_r = __pyx_v_whence;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":265
 * 
 * 
 * cdef int libc_whence_from_io(int whence):             # <<<<<<<<<<<<<<
 *     # io.SEEK_SET/_CUR/_END are by definition 0/1/2 but C/POSIX's equivalents
 *     # have unspecified values. So we must translate, but checking for 0/1/2
 */

  /* function exit code */
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_15_pysam_dispatch(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
PyDoc_STRVAR(__pyx_doc_5pysam_9libcutils_14_pysam_dispatch, "call ``method`` in samtools/bcftools providing arguments in args.\n    \n    By default, stdout is redirected to a temporary file using the patched\n    C sources except for a few commands that have an explicit output option\n    (typically: -o). In these commands (such as samtools view), this explicit\n    option is used. If *is_usage* is True, then these explicit output options\n    will not be used.\n\n    Catching of stdout can be turned off by setting *catch_stdout* to\n    False.\n    ");
static PyMethodDef __pyx_mdef_5pysam_9libcutils_15_pysam_dispatch = {"_pysam_dispatch", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_15_pysam_dispatch, __Pyx_METH_FASTCALL|METH_KEYWORDS, __pyx_doc_5pysam_9libcutils_14_pysam_dispatch};
static PyObject *__pyx_pw_5pysam_9libcutils_15_pysam_dispatch(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_collection = 0;
  PyObject *__pyx_v_method = 0;
  PyObject *__pyx_v_args = 0;
  PyObject *__pyx_v_catch_stdout = 0;
  PyObject *__pyx_v_is_usage = 0;
  PyObject *__pyx_v_save_stdout = 0;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[6] = {0,0,0,0,0,0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("_pysam_dispatch (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 275, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_collection,&__pyx_n_s_method,&__pyx_n_s_args,&__pyx_n_s_catch_stdout,&__pyx_n_s_is_usage,&__pyx_n_s_save_stdout,0};

    /* "pysam/libcutils.pyx":277
 * def _pysam_dispatch(collection,
 *                     method,
 *                     args=None,             # <<<<<<<<<<<<<<
 *                     catch_stdout=True,
 *                     is_usage=False,
 */
    values[2] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));

    /* "pysam/libcutils.pyx":278
 *                     method,
 *                     args=None,
 *                     catch_stdout=True,             # <<<<<<<<<<<<<<
 *                     is_usage=False,
 *                     save_stdout=None):
 */
    values[3] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)((PyObject *)Py_True)));

    /* "pysam/libcutils.pyx":279
 *                     args=None,
 *                     catch_stdout=True,
 *                     is_usage=False,             # <<<<<<<<<<<<<<
 *                     save_stdout=None):
 *     '''call ``method`` in samtools/bcftools providing arguments in args.
 */
    values[4] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)((PyObject *)Py_False)));

    /* "pysam/libcutils.pyx":280
 *                     catch_stdout=True,
 *                     is_usage=False,
 *                     save_stdout=None):             # <<<<<<<<<<<<<<
 *     '''call ``method`` in samtools/bcftools providing arguments in args.
 * 
 */
    values[5] = __Pyx_Arg_NewRef_FASTCALL(((PyObject *)Py_None));
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  6: values[5] = __Pyx_Arg_FASTCALL(__pyx_args, 5);
        CYTHON_FALLTHROUGH;
        case  5: values[4] = __Pyx_Arg_FASTCALL(__pyx_args, 4);
        CYTHON_FALLTHROUGH;
        case  4: values[3] = __Pyx_Arg_FASTCALL(__pyx_args, 3);
        CYTHON_FALLTHROUGH;
        case  3: values[2] = __Pyx_Arg_FASTCALL(__pyx_args, 2);
        CYTHON_FALLTHROUGH;
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        CYTHON_FALLTHROUGH;
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_collection)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
        CYTHON_FALLTHROUGH;
        case  1:
        if (likely((values[1] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_method)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[1]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        else {
          __Pyx_RaiseArgtupleInvalid("_pysam_dispatch", 0, 2, 6, 1); __PYX_ERR(0, 275, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  2:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_args);
          if (value) { values[2] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  3:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_catch_stdout);
          if (value) { values[3] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  4:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_is_usage);
          if (value) { values[4] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        }
        CYTHON_FALLTHROUGH;
        case  5:
        if (kw_args > 0) {
          PyObject* value = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_save_stdout);
          if (value) { values[5] = __Pyx_Arg_NewRef_FASTCALL(value); kw_args--; }
          else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 275, __pyx_L3_error)
        }
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "_pysam_dispatch") < 0)) __PYX_ERR(0, 275, __pyx_L3_error)
      }
    } else {
      switch (__pyx_nargs) {
        case  6: values[5] = __Pyx_Arg_FASTCALL(__pyx_args, 5);
        CYTHON_FALLTHROUGH;
        case  5: values[4] = __Pyx_Arg_FASTCALL(__pyx_args, 4);
        CYTHON_FALLTHROUGH;
        case  4: values[3] = __Pyx_Arg_FASTCALL(__pyx_args, 3);
        CYTHON_FALLTHROUGH;
        case  3: values[2] = __Pyx_Arg_FASTCALL(__pyx_args, 2);
        CYTHON_FALLTHROUGH;
        case  2: values[1] = __Pyx_Arg_FASTCALL(__pyx_args, 1);
        values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        break;
        default: goto __pyx_L5_argtuple_error;
      }
    }
    __pyx_v_collection = values[0];
    __pyx_v_method = values[1];
    __pyx_v_args = values[2];
    __pyx_v_catch_stdout = values[3];
    __pyx_v_is_usage = values[4];
    __pyx_v_save_stdout = values[5];
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("_pysam_dispatch", 0, 2, 6, __pyx_nargs); __PYX_ERR(0, 275, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_14_pysam_dispatch(__pyx_self, __pyx_v_collection, __pyx_v_method, __pyx_v_args, __pyx_v_catch_stdout, __pyx_v_is_usage, __pyx_v_save_stdout);

  /* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":412
 * 
 *     # get error messages
 *     def _collect(fn):             # <<<<<<<<<<<<<<
 *         out = []
 *         try:
 */

/* Python wrapper */
static PyObject *__pyx_pw_5pysam_9libcutils_15_pysam_dispatch_1_collect(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
); /*proto*/
static PyMethodDef __pyx_mdef_5pysam_9libcutils_15_pysam_dispatch_1_collect = {"_collect", (PyCFunction)(void*)(__Pyx_PyCFunction_FastCallWithKeywords)__pyx_pw_5pysam_9libcutils_15_pysam_dispatch_1_collect, __Pyx_METH_FASTCALL|METH_KEYWORDS, 0};
static PyObject *__pyx_pw_5pysam_9libcutils_15_pysam_dispatch_1_collect(PyObject *__pyx_self, 
#if CYTHON_METH_FASTCALL
PyObject *const *__pyx_args, Py_ssize_t __pyx_nargs, PyObject *__pyx_kwds
#else
PyObject *__pyx_args, PyObject *__pyx_kwds
#endif
) {
  PyObject *__pyx_v_fn = 0;
  #if !CYTHON_METH_FASTCALL
  CYTHON_UNUSED Py_ssize_t __pyx_nargs;
  #endif
  CYTHON_UNUSED PyObject *const *__pyx_kwvalues;
  PyObject* values[1] = {0};
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  PyObject *__pyx_r = 0;
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("_collect (wrapper)", 0);
  #if !CYTHON_METH_FASTCALL
  #if CYTHON_ASSUME_SAFE_MACROS
  __pyx_nargs = PyTuple_GET_SIZE(__pyx_args);
  #else
  __pyx_nargs = PyTuple_Size(__pyx_args);
  if (unlikely((__pyx_nargs < 0))) __PYX_ERR(0, 412, __pyx_L3_error)
  #endif
  #endif
  __pyx_kwvalues = __Pyx_KwValues_FASTCALL(__pyx_args, __pyx_nargs);
  {
    PyObject **__pyx_pyargnames[] = {&__pyx_n_s_fn,0};
    if (__pyx_kwds) {
      Py_ssize_t kw_args;
      switch (__pyx_nargs) {
        case  1: values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
        CYTHON_FALLTHROUGH;
        case  0: break;
        default: goto __pyx_L5_argtuple_error;
      }
      kw_args = __Pyx_NumKwargs_FASTCALL(__pyx_kwds);
      switch (__pyx_nargs) {
        case  0:
        if (likely((values[0] = __Pyx_GetKwValue_FASTCALL(__pyx_kwds, __pyx_kwvalues, __pyx_n_s_fn)) != 0)) {
          (void)__Pyx_Arg_NewRef_FASTCALL(values[0]);
          kw_args--;
        }
        else if (unlikely(PyErr_Occurred())) __PYX_ERR(0, 412, __pyx_L3_error)
        else goto __pyx_L5_argtuple_error;
      }
      if (unlikely(kw_args > 0)) {
        const Py_ssize_t kwd_pos_args = __pyx_nargs;
        if (unlikely(__Pyx_ParseOptionalKeywords(__pyx_kwds, __pyx_kwvalues, __pyx_pyargnames, 0, values + 0, kwd_pos_args, "_collect") < 0)) __PYX_ERR(0, 412, __pyx_L3_error)
      }
    } else if (unlikely(__pyx_nargs != 1)) {
      goto __pyx_L5_argtuple_error;
    } else {
      values[0] = __Pyx_Arg_FASTCALL(__pyx_args, 0);
    }
    __pyx_v_fn = values[0];
  }
  goto __pyx_L4_argument_unpacking_done;
  __pyx_L5_argtuple_error:;
  __Pyx_RaiseArgtupleInvalid("_collect", 1, 1, 1, __pyx_nargs); __PYX_ERR(0, 412, __pyx_L3_error)
  goto __pyx_L3_error;
  __pyx_L3_error:;
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch._collect", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __Pyx_RefNannyFinishContext();
  return NULL;
  __pyx_L4_argument_unpacking_done:;
  __pyx_r = __pyx_pf_5pysam_9libcutils_15_pysam_dispatch__collect(__pyx_self, __pyx_v_fn);

  /* function exit code */
  {
    Py_ssize_t __pyx_temp;
    for (__pyx_temp=0; __pyx_temp < (Py_ssize_t)(sizeof(values)/sizeof(values[0])); ++__pyx_temp) {
      __Pyx_Arg_XDECREF_FASTCALL(values[__pyx_temp]);
    }
  }
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyObject *__pyx_pf_5pysam_9libcutils_15_pysam_dispatch__collect(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_fn) {
  PyObject *__pyx_v_out = NULL;
  PyObject *__pyx_v_inf = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  PyObject *__pyx_t_5 = NULL;
  PyObject *__pyx_t_6 = NULL;
  PyObject *__pyx_t_7 = NULL;
  PyObject *__pyx_t_8 = NULL;
  int __pyx_t_9;
  PyObject *__pyx_t_10 = NULL;
  PyObject *__pyx_t_11 = NULL;
  PyObject *__pyx_t_12 = NULL;
  PyObject *__pyx_t_13 = NULL;
  int __pyx_t_14;
  int __pyx_t_15;
  PyObject *__pyx_t_16 = NULL;
  PyObject *__pyx_t_17 = NULL;
  PyObject *__pyx_t_18 = NULL;
  int __pyx_t_19;
  char const *__pyx_t_20;
  int __pyx_t_21;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("_collect", 0);

  /* "pysam/libcutils.pyx":413
 *     # get error messages
 *     def _collect(fn):
 *         out = []             # <<<<<<<<<<<<<<
 *         try:
 *             with open(fn, "r") as inf:
 */
  __pyx_t_1 = PyList_New(0); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 413, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_v_out = __pyx_t_1;
  __pyx_t_1 = 0;

  /* "pysam/libcutils.pyx":414
 *     def _collect(fn):
 *         out = []
 *         try:             # <<<<<<<<<<<<<<
 *             with open(fn, "r") as inf:
 *                 out = inf.read()
 */
  /*try:*/ {
    {
      __Pyx_PyThreadState_declare
      __Pyx_PyThreadState_assign
      __Pyx_ExceptionSave(&__pyx_t_2, &__pyx_t_3, &__pyx_t_4);
      __Pyx_XGOTREF(__pyx_t_2);
      __Pyx_XGOTREF(__pyx_t_3);
      __Pyx_XGOTREF(__pyx_t_4);
      /*try:*/ {

        /* "pysam/libcutils.pyx":415
 *         out = []
 *         try:
 *             with open(fn, "r") as inf:             # <<<<<<<<<<<<<<
 *                 out = inf.read()
 *         except UnicodeDecodeError:
 */
        /*with:*/ {
          __pyx_t_1 = PyTuple_New(2); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 415, __pyx_L6_error)
          __Pyx_GOTREF(__pyx_t_1);
          __Pyx_INCREF(__pyx_v_fn);
          __Pyx_GIVEREF(__pyx_v_fn);
          if (__Pyx_PyTuple_SET_ITEM(__pyx_t_1, 0, __pyx_v_fn)) __PYX_ERR(0, 415, __pyx_L6_error);
          __Pyx_INCREF(__pyx_n_u_r);
          __Pyx_GIVEREF(__pyx_n_u_r);
          if (__Pyx_PyTuple_SET_ITEM(__pyx_t_1, 1, __pyx_n_u_r)) __PYX_ERR(0, 415, __pyx_L6_error);
          __pyx_t_5 = __Pyx_PyObject_Call(__pyx_builtin_open, __pyx_t_1, NULL); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 415, __pyx_L6_error)
          __Pyx_GOTREF(__pyx_t_5);
          __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
          __pyx_t_6 = __Pyx_PyObject_LookupSpecial(__pyx_t_5, __pyx_n_s_exit); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 415, __pyx_L6_error)
          __Pyx_GOTREF(__pyx_t_6);
          __pyx_t_7 = __Pyx_PyObject_LookupSpecial(__pyx_t_5, __pyx_n_s_enter); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 415, __pyx_L12_error)
          __Pyx_GOTREF(__pyx_t_7);
          __pyx_t_8 = NULL;
          __pyx_t_9 = 0;
          #if CYTHON_UNPACK_METHODS
          if (likely(PyMethod_Check(__pyx_t_7))) {
            __pyx_t_8 = PyMethod_GET_SELF(__pyx_t_7);
            if (likely(__pyx_t_8)) {
              PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_7);
              __Pyx_INCREF(__pyx_t_8);
              __Pyx_INCREF(function);
              __Pyx_DECREF_SET(__pyx_t_7, function);
              __pyx_t_9 = 1;
            }
          }
          #endif
          {
            PyObject *__pyx_callargs[1] = {__pyx_t_8, };
            __pyx_t_1 = __Pyx_PyObject_FastCall(__pyx_t_7, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
            __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
            if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 415, __pyx_L12_error)
            __Pyx_GOTREF(__pyx_t_1);
            __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
          }
          __pyx_t_7 = __pyx_t_1;
          __pyx_t_1 = 0;
          __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
          /*try:*/ {
            {
              __Pyx_PyThreadState_declare
              __Pyx_PyThreadState_assign
              __Pyx_ExceptionSave(&__pyx_t_10, &__pyx_t_11, &__pyx_t_12);
              __Pyx_XGOTREF(__pyx_t_10);
              __Pyx_XGOTREF(__pyx_t_11);
              __Pyx_XGOTREF(__pyx_t_12);
              /*try:*/ {
                __pyx_v_inf = __pyx_t_7;
                __pyx_t_7 = 0;

                /* "pysam/libcutils.pyx":416
 *         try:
 *             with open(fn, "r") as inf:
 *                 out = inf.read()             # <<<<<<<<<<<<<<
 *         except UnicodeDecodeError:
 *             with open(fn, "rb") as inf:
 */
                __pyx_t_5 = __Pyx_PyObject_GetAttrStr(__pyx_v_inf, __pyx_n_s_read); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 416, __pyx_L16_error)
                __Pyx_GOTREF(__pyx_t_5);
                __pyx_t_1 = NULL;
                __pyx_t_9 = 0;
                #if CYTHON_UNPACK_METHODS
                if (likely(PyMethod_Check(__pyx_t_5))) {
                  __pyx_t_1 = PyMethod_GET_SELF(__pyx_t_5);
                  if (likely(__pyx_t_1)) {
                    PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_5);
                    __Pyx_INCREF(__pyx_t_1);
                    __Pyx_INCREF(function);
                    __Pyx_DECREF_SET(__pyx_t_5, function);
                    __pyx_t_9 = 1;
                  }
                }
                #endif
                {
                  PyObject *__pyx_callargs[1] = {__pyx_t_1, };
                  __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_5, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
                  __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
                  if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 416, __pyx_L16_error)
                  __Pyx_GOTREF(__pyx_t_7);
                  __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
                }
                __Pyx_DECREF_SET(__pyx_v_out, __pyx_t_7);
                __pyx_t_7 = 0;

                /* "pysam/libcutils.pyx":415
 *         out = []
 *         try:
 *             with open(fn, "r") as inf:             # <<<<<<<<<<<<<<
 *                 out = inf.read()
 *         except UnicodeDecodeError:
 */
              }
              __Pyx_XDECREF(__pyx_t_10); __pyx_t_10 = 0;
              __Pyx_XDECREF(__pyx_t_11); __pyx_t_11 = 0;
              __Pyx_XDECREF(__pyx_t_12); __pyx_t_12 = 0;
              goto __pyx_L21_try_end;
              __pyx_L16_error:;
              __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
              __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
              __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
              __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
              /*except:*/ {
                __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch._collect", __pyx_clineno, __pyx_lineno, __pyx_filename);
                if (__Pyx_GetException(&__pyx_t_7, &__pyx_t_5, &__pyx_t_1) < 0) __PYX_ERR(0, 415, __pyx_L18_except_error)
                __Pyx_XGOTREF(__pyx_t_7);
                __Pyx_XGOTREF(__pyx_t_5);
                __Pyx_XGOTREF(__pyx_t_1);
                __pyx_t_8 = PyTuple_Pack(3, __pyx_t_7, __pyx_t_5, __pyx_t_1); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 415, __pyx_L18_except_error)
                __Pyx_GOTREF(__pyx_t_8);
                __pyx_t_13 = __Pyx_PyObject_Call(__pyx_t_6, __pyx_t_8, NULL);
                __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
                __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
                if (unlikely(!__pyx_t_13)) __PYX_ERR(0, 415, __pyx_L18_except_error)
                __Pyx_GOTREF(__pyx_t_13);
                __pyx_t_14 = __Pyx_PyObject_IsTrue(__pyx_t_13);
                __Pyx_DECREF(__pyx_t_13); __pyx_t_13 = 0;
                if (__pyx_t_14 < 0) __PYX_ERR(0, 415, __pyx_L18_except_error)
                __pyx_t_15 = (!__pyx_t_14);
                if (unlikely(__pyx_t_15)) {
                  __Pyx_GIVEREF(__pyx_t_7);
                  __Pyx_GIVEREF(__pyx_t_5);
                  __Pyx_XGIVEREF(__pyx_t_1);
                  __Pyx_ErrRestoreWithState(__pyx_t_7, __pyx_t_5, __pyx_t_1);
                  __pyx_t_7 = 0; __pyx_t_5 = 0; __pyx_t_1 = 0; 
                  __PYX_ERR(0, 415, __pyx_L18_except_error)
                }
                __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
                __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
                __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
                goto __pyx_L17_exception_handled;
              }
              __pyx_L18_except_error:;
              __Pyx_XGIVEREF(__pyx_t_10);
              __Pyx_XGIVEREF(__pyx_t_11);
              __Pyx_XGIVEREF(__pyx_t_12);
              __Pyx_ExceptionReset(__pyx_t_10, __pyx_t_11, __pyx_t_12);
              goto __pyx_L6_error;
              __pyx_L17_exception_handled:;
              __Pyx_XGIVEREF(__pyx_t_10);
              __Pyx_XGIVEREF(__pyx_t_11);
              __Pyx_XGIVEREF(__pyx_t_12);
              __Pyx_ExceptionReset(__pyx_t_10, __pyx_t_11, __pyx_t_12);
              __pyx_L21_try_end:;
            }
          }
          /*finally:*/ {
            /*normal exit:*/{
              if (__pyx_t_6) {
                __pyx_t_12 = __Pyx_PyObject_Call(__pyx_t_6, __pyx_tuple__9, NULL);
                __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
                if (unlikely(!__pyx_t_12)) __PYX_ERR(0, 415, __pyx_L6_error)
                __Pyx_GOTREF(__pyx_t_12);
                __Pyx_DECREF(__pyx_t_12); __pyx_t_12 = 0;
              }
              goto __pyx_L15;
            }
            __pyx_L15:;
          }
          goto __pyx_L25;
          __pyx_L12_error:;
          __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
          goto __pyx_L6_error;
          __pyx_L25:;
        }

        /* "pysam/libcutils.pyx":414
 *     def _collect(fn):
 *         out = []
 *         try:             # <<<<<<<<<<<<<<
 *             with open(fn, "r") as inf:
 *                 out = inf.read()
 */
      }
      __Pyx_XDECREF(__pyx_t_2); __pyx_t_2 = 0;
      __Pyx_XDECREF(__pyx_t_3); __pyx_t_3 = 0;
      __Pyx_XDECREF(__pyx_t_4); __pyx_t_4 = 0;
      goto __pyx_L11_try_end;
      __pyx_L6_error:;
      __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
      __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
      __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
      __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;

      /* "pysam/libcutils.pyx":417
 *             with open(fn, "r") as inf:
 *                 out = inf.read()
 *         except UnicodeDecodeError:             # <<<<<<<<<<<<<<
 *             with open(fn, "rb") as inf:
 *                 # read binary output
 */
      __pyx_t_9 = __Pyx_PyErr_ExceptionMatches(__pyx_builtin_UnicodeDecodeError);
      if (__pyx_t_9) {
        __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch._collect", __pyx_clineno, __pyx_lineno, __pyx_filename);
        if (__Pyx_GetException(&__pyx_t_1, &__pyx_t_5, &__pyx_t_7) < 0) __PYX_ERR(0, 417, __pyx_L8_except_error)
        __Pyx_XGOTREF(__pyx_t_1);
        __Pyx_XGOTREF(__pyx_t_5);
        __Pyx_XGOTREF(__pyx_t_7);

        /* "pysam/libcutils.pyx":418
 *                 out = inf.read()
 *         except UnicodeDecodeError:
 *             with open(fn, "rb") as inf:             # <<<<<<<<<<<<<<
 *                 # read binary output
 *                 out = inf.read()
 */
        /*with:*/ {
          __pyx_t_8 = PyTuple_New(2); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 418, __pyx_L8_except_error)
          __Pyx_GOTREF(__pyx_t_8);
          __Pyx_INCREF(__pyx_v_fn);
          __Pyx_GIVEREF(__pyx_v_fn);
          if (__Pyx_PyTuple_SET_ITEM(__pyx_t_8, 0, __pyx_v_fn)) __PYX_ERR(0, 418, __pyx_L8_except_error);
          __Pyx_INCREF(__pyx_n_u_rb);
          __Pyx_GIVEREF(__pyx_n_u_rb);
          if (__Pyx_PyTuple_SET_ITEM(__pyx_t_8, 1, __pyx_n_u_rb)) __PYX_ERR(0, 418, __pyx_L8_except_error);
          __pyx_t_16 = __Pyx_PyObject_Call(__pyx_builtin_open, __pyx_t_8, NULL); if (unlikely(!__pyx_t_16)) __PYX_ERR(0, 418, __pyx_L8_except_error)
          __Pyx_GOTREF(__pyx_t_16);
          __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
          __pyx_t_6 = __Pyx_PyObject_LookupSpecial(__pyx_t_16, __pyx_n_s_exit); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 418, __pyx_L8_except_error)
          __Pyx_GOTREF(__pyx_t_6);
          __pyx_t_17 = __Pyx_PyObject_LookupSpecial(__pyx_t_16, __pyx_n_s_enter); if (unlikely(!__pyx_t_17)) __PYX_ERR(0, 418, __pyx_L28_error)
          __Pyx_GOTREF(__pyx_t_17);
          __pyx_t_18 = NULL;
          __pyx_t_9 = 0;
          #if CYTHON_UNPACK_METHODS
          if (likely(PyMethod_Check(__pyx_t_17))) {
            __pyx_t_18 = PyMethod_GET_SELF(__pyx_t_17);
            if (likely(__pyx_t_18)) {
              PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_17);
              __Pyx_INCREF(__pyx_t_18);
              __Pyx_INCREF(function);
              __Pyx_DECREF_SET(__pyx_t_17, function);
              __pyx_t_9 = 1;
            }
          }
          #endif
          {
            PyObject *__pyx_callargs[1] = {__pyx_t_18, };
            __pyx_t_8 = __Pyx_PyObject_FastCall(__pyx_t_17, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
            __Pyx_XDECREF(__pyx_t_18); __pyx_t_18 = 0;
            if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 418, __pyx_L28_error)
            __Pyx_GOTREF(__pyx_t_8);
            __Pyx_DECREF(__pyx_t_17); __pyx_t_17 = 0;
          }
          __pyx_t_17 = __pyx_t_8;
          __pyx_t_8 = 0;
          __Pyx_DECREF(__pyx_t_16); __pyx_t_16 = 0;
          /*try:*/ {
            {
              __Pyx_PyThreadState_declare
              __Pyx_PyThreadState_assign
              __Pyx_ExceptionSave(&__pyx_t_12, &__pyx_t_11, &__pyx_t_10);
              __Pyx_XGOTREF(__pyx_t_12);
              __Pyx_XGOTREF(__pyx_t_11);
              __Pyx_XGOTREF(__pyx_t_10);
              /*try:*/ {
                __Pyx_XDECREF_SET(__pyx_v_inf, __pyx_t_17);
                __pyx_t_17 = 0;

                /* "pysam/libcutils.pyx":420
 *             with open(fn, "rb") as inf:
 *                 # read binary output
 *                 out = inf.read()             # <<<<<<<<<<<<<<
 *         finally:
 *             os.remove(fn)
 */
                __pyx_t_16 = __Pyx_PyObject_GetAttrStr(__pyx_v_inf, __pyx_n_s_read); if (unlikely(!__pyx_t_16)) __PYX_ERR(0, 420, __pyx_L34_error)
                __Pyx_GOTREF(__pyx_t_16);
                __pyx_t_8 = NULL;
                __pyx_t_9 = 0;
                #if CYTHON_UNPACK_METHODS
                if (likely(PyMethod_Check(__pyx_t_16))) {
                  __pyx_t_8 = PyMethod_GET_SELF(__pyx_t_16);
                  if (likely(__pyx_t_8)) {
                    PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_16);
                    __Pyx_INCREF(__pyx_t_8);
                    __Pyx_INCREF(function);
                    __Pyx_DECREF_SET(__pyx_t_16, function);
                    __pyx_t_9 = 1;
                  }
                }
                #endif
                {
                  PyObject *__pyx_callargs[1] = {__pyx_t_8, };
                  __pyx_t_17 = __Pyx_PyObject_FastCall(__pyx_t_16, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
                  __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
                  if (unlikely(!__pyx_t_17)) __PYX_ERR(0, 420, __pyx_L34_error)
                  __Pyx_GOTREF(__pyx_t_17);
                  __Pyx_DECREF(__pyx_t_16); __pyx_t_16 = 0;
                }
                __Pyx_DECREF_SET(__pyx_v_out, __pyx_t_17);
                __pyx_t_17 = 0;

                /* "pysam/libcutils.pyx":418
 *                 out = inf.read()
 *         except UnicodeDecodeError:
 *             with open(fn, "rb") as inf:             # <<<<<<<<<<<<<<
 *                 # read binary output
 *                 out = inf.read()
 */
              }
              __Pyx_XDECREF(__pyx_t_12); __pyx_t_12 = 0;
              __Pyx_XDECREF(__pyx_t_11); __pyx_t_11 = 0;
              __Pyx_XDECREF(__pyx_t_10); __pyx_t_10 = 0;
              goto __pyx_L41_try_end;
              __pyx_L34_error:;
              __Pyx_XDECREF(__pyx_t_16); __pyx_t_16 = 0;
              __Pyx_XDECREF(__pyx_t_17); __pyx_t_17 = 0;
              __Pyx_XDECREF(__pyx_t_18); __pyx_t_18 = 0;
              __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
              /*except:*/ {
                __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch._collect", __pyx_clineno, __pyx_lineno, __pyx_filename);
                if (__Pyx_GetException(&__pyx_t_17, &__pyx_t_16, &__pyx_t_8) < 0) __PYX_ERR(0, 418, __pyx_L36_except_error)
                __Pyx_XGOTREF(__pyx_t_17);
                __Pyx_XGOTREF(__pyx_t_16);
                __Pyx_XGOTREF(__pyx_t_8);
                __pyx_t_18 = PyTuple_Pack(3, __pyx_t_17, __pyx_t_16, __pyx_t_8); if (unlikely(!__pyx_t_18)) __PYX_ERR(0, 418, __pyx_L36_except_error)
                __Pyx_GOTREF(__pyx_t_18);
                __pyx_t_13 = __Pyx_PyObject_Call(__pyx_t_6, __pyx_t_18, NULL);
                __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
                __Pyx_DECREF(__pyx_t_18); __pyx_t_18 = 0;
                if (unlikely(!__pyx_t_13)) __PYX_ERR(0, 418, __pyx_L36_except_error)
                __Pyx_GOTREF(__pyx_t_13);
                __pyx_t_15 = __Pyx_PyObject_IsTrue(__pyx_t_13);
                __Pyx_DECREF(__pyx_t_13); __pyx_t_13 = 0;
                if (__pyx_t_15 < 0) __PYX_ERR(0, 418, __pyx_L36_except_error)
                __pyx_t_14 = (!__pyx_t_15);
                if (unlikely(__pyx_t_14)) {
                  __Pyx_GIVEREF(__pyx_t_17);
                  __Pyx_GIVEREF(__pyx_t_16);
                  __Pyx_XGIVEREF(__pyx_t_8);
                  __Pyx_ErrRestoreWithState(__pyx_t_17, __pyx_t_16, __pyx_t_8);
                  __pyx_t_17 = 0; __pyx_t_16 = 0; __pyx_t_8 = 0; 
                  __PYX_ERR(0, 418, __pyx_L36_except_error)
                }
                __Pyx_XDECREF(__pyx_t_17); __pyx_t_17 = 0;
                __Pyx_XDECREF(__pyx_t_16); __pyx_t_16 = 0;
                __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
                goto __pyx_L35_exception_handled;
              }
              __pyx_L36_except_error:;
              __Pyx_XGIVEREF(__pyx_t_12);
              __Pyx_XGIVEREF(__pyx_t_11);
              __Pyx_XGIVEREF(__pyx_t_10);
              __Pyx_ExceptionReset(__pyx_t_12, __pyx_t_11, __pyx_t_10);
              goto __pyx_L8_except_error;
              __pyx_L35_exception_handled:;
              __Pyx_XGIVEREF(__pyx_t_12);
              __Pyx_XGIVEREF(__pyx_t_11);
              __Pyx_XGIVEREF(__pyx_t_10);
              __Pyx_ExceptionReset(__pyx_t_12, __pyx_t_11, __pyx_t_10);
              __pyx_L41_try_end:;
            }
          }
          /*finally:*/ {
            /*normal exit:*/{
              if (__pyx_t_6) {
                __pyx_t_10 = __Pyx_PyObject_Call(__pyx_t_6, __pyx_tuple__9, NULL);
                __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
                if (unlikely(!__pyx_t_10)) __PYX_ERR(0, 418, __pyx_L8_except_error)
                __Pyx_GOTREF(__pyx_t_10);
                __Pyx_DECREF(__pyx_t_10); __pyx_t_10 = 0;
              }
              goto __pyx_L33;
            }
            __pyx_L33:;
          }
          goto __pyx_L45;
          __pyx_L28_error:;
          __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
          goto __pyx_L8_except_error;
          __pyx_L45:;
        }
        __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
        __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
        __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
        goto __pyx_L7_exception_handled;
      }
      goto __pyx_L8_except_error;

      /* "pysam/libcutils.pyx":414
 *     def _collect(fn):
 *         out = []
 *         try:             # <<<<<<<<<<<<<<
 *             with open(fn, "r") as inf:
 *                 out = inf.read()
 */
      __pyx_L8_except_error:;
      __Pyx_XGIVEREF(__pyx_t_2);
      __Pyx_XGIVEREF(__pyx_t_3);
      __Pyx_XGIVEREF(__pyx_t_4);
      __Pyx_ExceptionReset(__pyx_t_2, __pyx_t_3, __pyx_t_4);
      goto __pyx_L4_error;
      __pyx_L7_exception_handled:;
      __Pyx_XGIVEREF(__pyx_t_2);
      __Pyx_XGIVEREF(__pyx_t_3);
      __Pyx_XGIVEREF(__pyx_t_4);
      __Pyx_ExceptionReset(__pyx_t_2, __pyx_t_3, __pyx_t_4);
      __pyx_L11_try_end:;
    }
  }

  /* "pysam/libcutils.pyx":422
 *                 out = inf.read()
 *         finally:
 *             os.remove(fn)             # <<<<<<<<<<<<<<
 *         return out
 * 
 */
  /*finally:*/ {
    /*normal exit:*/{
      __Pyx_GetModuleGlobalName(__pyx_t_5, __pyx_n_s_os); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 422, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_5);
      __pyx_t_1 = __Pyx_PyObject_GetAttrStr(__pyx_t_5, __pyx_n_s_remove); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 422, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_1);
      __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
      __pyx_t_5 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (unlikely(PyMethod_Check(__pyx_t_1))) {
        __pyx_t_5 = PyMethod_GET_SELF(__pyx_t_1);
        if (likely(__pyx_t_5)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_1);
          __Pyx_INCREF(__pyx_t_5);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_1, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_5, __pyx_v_fn};
        __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_1, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
        if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 422, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
      }
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      goto __pyx_L5;
    }
    __pyx_L4_error:;
    /*exception exit:*/{
      __Pyx_PyThreadState_declare
      __Pyx_PyThreadState_assign
      __pyx_t_4 = 0; __pyx_t_3 = 0; __pyx_t_2 = 0; __pyx_t_6 = 0; __pyx_t_10 = 0; __pyx_t_11 = 0;
      __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
      __Pyx_XDECREF(__pyx_t_16); __pyx_t_16 = 0;
      __Pyx_XDECREF(__pyx_t_17); __pyx_t_17 = 0;
      __Pyx_XDECREF(__pyx_t_18); __pyx_t_18 = 0;
      __Pyx_XDECREF(__pyx_t_5); __pyx_t_5 = 0;
      __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
      __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
      if (PY_MAJOR_VERSION >= 3) __Pyx_ExceptionSwap(&__pyx_t_6, &__pyx_t_10, &__pyx_t_11);
      if ((PY_MAJOR_VERSION < 3) || unlikely(__Pyx_GetException(&__pyx_t_4, &__pyx_t_3, &__pyx_t_2) < 0)) __Pyx_ErrFetch(&__pyx_t_4, &__pyx_t_3, &__pyx_t_2);
      __Pyx_XGOTREF(__pyx_t_4);
      __Pyx_XGOTREF(__pyx_t_3);
      __Pyx_XGOTREF(__pyx_t_2);
      __Pyx_XGOTREF(__pyx_t_6);
      __Pyx_XGOTREF(__pyx_t_10);
      __Pyx_XGOTREF(__pyx_t_11);
      __pyx_t_9 = __pyx_lineno; __pyx_t_19 = __pyx_clineno; __pyx_t_20 = __pyx_filename;
      {
        __Pyx_GetModuleGlobalName(__pyx_t_1, __pyx_n_s_os); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 422, __pyx_L47_error)
        __Pyx_GOTREF(__pyx_t_1);
        __pyx_t_5 = __Pyx_PyObject_GetAttrStr(__pyx_t_1, __pyx_n_s_remove); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 422, __pyx_L47_error)
        __Pyx_GOTREF(__pyx_t_5);
        __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
        __pyx_t_1 = NULL;
        __pyx_t_21 = 0;
        #if CYTHON_UNPACK_METHODS
        if (unlikely(PyMethod_Check(__pyx_t_5))) {
          __pyx_t_1 = PyMethod_GET_SELF(__pyx_t_5);
          if (likely(__pyx_t_1)) {
            PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_5);
            __Pyx_INCREF(__pyx_t_1);
            __Pyx_INCREF(function);
            __Pyx_DECREF_SET(__pyx_t_5, function);
            __pyx_t_21 = 1;
          }
        }
        #endif
        {
          PyObject *__pyx_callargs[2] = {__pyx_t_1, __pyx_v_fn};
          __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_5, __pyx_callargs+1-__pyx_t_21, 1+__pyx_t_21);
          __Pyx_XDECREF(__pyx_t_1); __pyx_t_1 = 0;
          if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 422, __pyx_L47_error)
          __Pyx_GOTREF(__pyx_t_7);
          __Pyx_DECREF(__pyx_t_5); __pyx_t_5 = 0;
        }
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      }
      if (PY_MAJOR_VERSION >= 3) {
        __Pyx_XGIVEREF(__pyx_t_6);
        __Pyx_XGIVEREF(__pyx_t_10);
        __Pyx_XGIVEREF(__pyx_t_11);
        __Pyx_ExceptionReset(__pyx_t_6, __pyx_t_10, __pyx_t_11);
      }
      __Pyx_XGIVEREF(__pyx_t_4);
      __Pyx_XGIVEREF(__pyx_t_3);
      __Pyx_XGIVEREF(__pyx_t_2);
      __Pyx_ErrRestore(__pyx_t_4, __pyx_t_3, __pyx_t_2);
      __pyx_t_4 = 0; __pyx_t_3 = 0; __pyx_t_2 = 0; __pyx_t_6 = 0; __pyx_t_10 = 0; __pyx_t_11 = 0;
      __pyx_lineno = __pyx_t_9; __pyx_clineno = __pyx_t_19; __pyx_filename = __pyx_t_20;
      goto __pyx_L1_error;
      __pyx_L47_error:;
      if (PY_MAJOR_VERSION >= 3) {
        __Pyx_XGIVEREF(__pyx_t_6);
        __Pyx_XGIVEREF(__pyx_t_10);
        __Pyx_XGIVEREF(__pyx_t_11);
        __Pyx_ExceptionReset(__pyx_t_6, __pyx_t_10, __pyx_t_11);
      }
      __Pyx_XDECREF(__pyx_t_4); __pyx_t_4 = 0;
      __Pyx_XDECREF(__pyx_t_3); __pyx_t_3 = 0;
      __Pyx_XDECREF(__pyx_t_2); __pyx_t_2 = 0;
      __pyx_t_6 = 0; __pyx_t_10 = 0; __pyx_t_11 = 0;
      goto __pyx_L1_error;
    }
    __pyx_L5:;
  }

  /* "pysam/libcutils.pyx":423
 *         finally:
 *             os.remove(fn)
 *         return out             # <<<<<<<<<<<<<<
 * 
 *     out_stderr = _collect(stderr_f)
 */
  __Pyx_XDECREF(__pyx_r);
  __Pyx_INCREF(__pyx_v_out);
  __pyx_r = __pyx_v_out;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":412
 * 
 *     # get error messages
 *     def _collect(fn):             # <<<<<<<<<<<<<<
 *         out = []
 *         try:
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_XDECREF(__pyx_t_5);
  __Pyx_XDECREF(__pyx_t_7);
  __Pyx_XDECREF(__pyx_t_8);
  __Pyx_XDECREF(__pyx_t_16);
  __Pyx_XDECREF(__pyx_t_17);
  __Pyx_XDECREF(__pyx_t_18);
  __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch._collect", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_out);
  __Pyx_XDECREF(__pyx_v_inf);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

/* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */

static PyObject *__pyx_pf_5pysam_9libcutils_14_pysam_dispatch(CYTHON_UNUSED PyObject *__pyx_self, PyObject *__pyx_v_collection, PyObject *__pyx_v_method, PyObject *__pyx_v_args, PyObject *__pyx_v_catch_stdout, PyObject *__pyx_v_is_usage, PyObject *__pyx_v_save_stdout) {
  PyObject *__pyx_v_ARGUMENTS = NULL;
  int __pyx_v_skip_next;
  PyObject *__pyx_v_arg = NULL;
  PyObject *__pyx_v_stderr_h = NULL;
  PyObject *__pyx_v_stderr_f = NULL;
  PyObject *__pyx_v_stdout_f = NULL;
  PyObject *__pyx_v_stdout_h = NULL;
  PyObject *__pyx_v_MAP_STDOUT_OPTIONS = NULL;
  PyObject *__pyx_v_stdout_option = NULL;
  char **__pyx_v_cargs;
  int __pyx_v_i;
  int __pyx_v_n;
  int __pyx_v_retval;
  int __pyx_v_l;
  int __pyx_v_extra_args;
  PyObject *__pyx_v__collect = 0;
  PyObject *__pyx_v_out_stderr = NULL;
  PyObject *__pyx_v_out_stdout = NULL;
  PyObject *__pyx_8genexpr2__pyx_v_a = NULL;
  PyObject *__pyx_r = NULL;
  __Pyx_RefNannyDeclarations
  int __pyx_t_1;
  int __pyx_t_2;
  PyObject *__pyx_t_3 = NULL;
  Py_ssize_t __pyx_t_4;
  PyObject *(*__pyx_t_5)(PyObject *);
  PyObject *__pyx_t_6 = NULL;
  PyObject *__pyx_t_7 = NULL;
  PyObject *__pyx_t_8 = NULL;
  int __pyx_t_9;
  PyObject *(*__pyx_t_10)(PyObject *);
  char const *__pyx_t_11;
  char const *__pyx_t_12;
  char const *__pyx_t_13;
  int __pyx_t_14;
  PyObject *__pyx_t_15 = NULL;
  PyObject *__pyx_t_16 = NULL;
  char *__pyx_t_17;
  char const *__pyx_t_18;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("_pysam_dispatch", 0);
  __Pyx_INCREF(__pyx_v_collection);
  __Pyx_INCREF(__pyx_v_method);
  __Pyx_INCREF(__pyx_v_args);

  /* "pysam/libcutils.pyx":293
 *     '''
 * 
 *     if method == "index" and args:             # <<<<<<<<<<<<<<
 *         # We make sure that at least the first specified input file exists,
 *         # and if it doesn't we raise an IOError.
 */
  __pyx_t_2 = (__Pyx_PyUnicode_Equals(__pyx_v_method, __pyx_n_u_index, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 293, __pyx_L1_error)
  if (__pyx_t_2) {
  } else {
    __pyx_t_1 = __pyx_t_2;
    goto __pyx_L4_bool_binop_done;
  }
  __pyx_t_2 = __Pyx_PyObject_IsTrue(__pyx_v_args); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 293, __pyx_L1_error)
  __pyx_t_1 = __pyx_t_2;
  __pyx_L4_bool_binop_done:;
  if (__pyx_t_1) {

    /* "pysam/libcutils.pyx":296
 *         # We make sure that at least the first specified input file exists,
 *         # and if it doesn't we raise an IOError.
 *         ARGUMENTS = ['-m', '--min-shift', '-o', '--output', '--output-file', '-@', '--threads']             # <<<<<<<<<<<<<<
 *         skip_next = False
 *         for arg in args:
 */
    __pyx_t_3 = PyList_New(7); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 296, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __Pyx_INCREF(__pyx_kp_u_m);
    __Pyx_GIVEREF(__pyx_kp_u_m);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 0, __pyx_kp_u_m)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u_min_shift);
    __Pyx_GIVEREF(__pyx_kp_u_min_shift);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 1, __pyx_kp_u_min_shift)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u_o);
    __Pyx_GIVEREF(__pyx_kp_u_o);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 2, __pyx_kp_u_o)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u_output);
    __Pyx_GIVEREF(__pyx_kp_u_output);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 3, __pyx_kp_u_output)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u_output_file);
    __Pyx_GIVEREF(__pyx_kp_u_output_file);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 4, __pyx_kp_u_output_file)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u__10);
    __Pyx_GIVEREF(__pyx_kp_u__10);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 5, __pyx_kp_u__10)) __PYX_ERR(0, 296, __pyx_L1_error);
    __Pyx_INCREF(__pyx_kp_u_threads);
    __Pyx_GIVEREF(__pyx_kp_u_threads);
    if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 6, __pyx_kp_u_threads)) __PYX_ERR(0, 296, __pyx_L1_error);
    __pyx_v_ARGUMENTS = ((PyObject*)__pyx_t_3);
    __pyx_t_3 = 0;

    /* "pysam/libcutils.pyx":297
 *         # and if it doesn't we raise an IOError.
 *         ARGUMENTS = ['-m', '--min-shift', '-o', '--output', '--output-file', '-@', '--threads']
 *         skip_next = False             # <<<<<<<<<<<<<<
 *         for arg in args:
 *             if skip_next:
 */
    __pyx_v_skip_next = 0;

    /* "pysam/libcutils.pyx":298
 *         ARGUMENTS = ['-m', '--min-shift', '-o', '--output', '--output-file', '-@', '--threads']
 *         skip_next = False
 *         for arg in args:             # <<<<<<<<<<<<<<
 *             if skip_next:
 *                 skip_next = False
 */
    if (likely(PyList_CheckExact(__pyx_v_args)) || PyTuple_CheckExact(__pyx_v_args)) {
      __pyx_t_3 = __pyx_v_args; __Pyx_INCREF(__pyx_t_3); __pyx_t_4 = 0;
      __pyx_t_5 = NULL;
    } else {
      __pyx_t_4 = -1; __pyx_t_3 = PyObject_GetIter(__pyx_v_args); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 298, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_3);
      __pyx_t_5 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_3); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 298, __pyx_L1_error)
    }
    for (;;) {
      if (likely(!__pyx_t_5)) {
        if (likely(PyList_CheckExact(__pyx_t_3))) {
          if (__pyx_t_4 >= PyList_GET_SIZE(__pyx_t_3)) break;
          #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
          __pyx_t_6 = PyList_GET_ITEM(__pyx_t_3, __pyx_t_4); __Pyx_INCREF(__pyx_t_6); __pyx_t_4++; if (unlikely((0 < 0))) __PYX_ERR(0, 298, __pyx_L1_error)
          #else
          __pyx_t_6 = PySequence_ITEM(__pyx_t_3, __pyx_t_4); __pyx_t_4++; if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 298, __pyx_L1_error)
          __Pyx_GOTREF(__pyx_t_6);
          #endif
        } else {
          if (__pyx_t_4 >= PyTuple_GET_SIZE(__pyx_t_3)) break;
          #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
          __pyx_t_6 = PyTuple_GET_ITEM(__pyx_t_3, __pyx_t_4); __Pyx_INCREF(__pyx_t_6); __pyx_t_4++; if (unlikely((0 < 0))) __PYX_ERR(0, 298, __pyx_L1_error)
          #else
          __pyx_t_6 = PySequence_ITEM(__pyx_t_3, __pyx_t_4); __pyx_t_4++; if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 298, __pyx_L1_error)
          __Pyx_GOTREF(__pyx_t_6);
          #endif
        }
      } else {
        __pyx_t_6 = __pyx_t_5(__pyx_t_3);
        if (unlikely(!__pyx_t_6)) {
          PyObject* exc_type = PyErr_Occurred();
          if (exc_type) {
            if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) PyErr_Clear();
            else __PYX_ERR(0, 298, __pyx_L1_error)
          }
          break;
        }
        __Pyx_GOTREF(__pyx_t_6);
      }
      __Pyx_XDECREF_SET(__pyx_v_arg, __pyx_t_6);
      __pyx_t_6 = 0;

      /* "pysam/libcutils.pyx":299
 *         skip_next = False
 *         for arg in args:
 *             if skip_next:             # <<<<<<<<<<<<<<
 *                 skip_next = False
 *                 continue
 */
      if (__pyx_v_skip_next) {

        /* "pysam/libcutils.pyx":300
 *         for arg in args:
 *             if skip_next:
 *                 skip_next = False             # <<<<<<<<<<<<<<
 *                 continue
 *             if arg.startswith('-'):
 */
        __pyx_v_skip_next = 0;

        /* "pysam/libcutils.pyx":301
 *             if skip_next:
 *                 skip_next = False
 *                 continue             # <<<<<<<<<<<<<<
 *             if arg.startswith('-'):
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 */
        goto __pyx_L6_continue;

        /* "pysam/libcutils.pyx":299
 *         skip_next = False
 *         for arg in args:
 *             if skip_next:             # <<<<<<<<<<<<<<
 *                 skip_next = False
 *                 continue
 */
      }

      /* "pysam/libcutils.pyx":302
 *                 skip_next = False
 *                 continue
 *             if arg.startswith('-'):             # <<<<<<<<<<<<<<
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 *                 if arg in ARGUMENTS:
 */
      __pyx_t_7 = __Pyx_PyObject_GetAttrStr(__pyx_v_arg, __pyx_n_s_startswith); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 302, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      __pyx_t_8 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_7))) {
        __pyx_t_8 = PyMethod_GET_SELF(__pyx_t_7);
        if (likely(__pyx_t_8)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_7);
          __Pyx_INCREF(__pyx_t_8);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_7, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_8, __pyx_kp_u__8};
        __pyx_t_6 = __Pyx_PyObject_FastCall(__pyx_t_7, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
        if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 302, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_6);
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      }
      __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_t_6); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 302, __pyx_L1_error)
      __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
      if (__pyx_t_1) {

        /* "pysam/libcutils.pyx":304
 *             if arg.startswith('-'):
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 *                 if arg in ARGUMENTS:             # <<<<<<<<<<<<<<
 *                     skip_next = True
 *                 continue
 */
        __pyx_t_1 = (__Pyx_PySequence_ContainsTF(__pyx_v_arg, __pyx_v_ARGUMENTS, Py_EQ)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 304, __pyx_L1_error)
        if (__pyx_t_1) {

          /* "pysam/libcutils.pyx":305
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 *                 if arg in ARGUMENTS:
 *                     skip_next = True             # <<<<<<<<<<<<<<
 *                 continue
 *             if not os.path.exists(arg):
 */
          __pyx_v_skip_next = 1;

          /* "pysam/libcutils.pyx":304
 *             if arg.startswith('-'):
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 *                 if arg in ARGUMENTS:             # <<<<<<<<<<<<<<
 *                     skip_next = True
 *                 continue
 */
        }

        /* "pysam/libcutils.pyx":306
 *                 if arg in ARGUMENTS:
 *                     skip_next = True
 *                 continue             # <<<<<<<<<<<<<<
 *             if not os.path.exists(arg):
 *                 raise IOError("No such file or directory: '%s'" % arg)
 */
        goto __pyx_L6_continue;

        /* "pysam/libcutils.pyx":302
 *                 skip_next = False
 *                 continue
 *             if arg.startswith('-'):             # <<<<<<<<<<<<<<
 *                 # Skip next argument for e.g. '--min-shift' '12' or '-m' '12' but not '-m12'
 *                 if arg in ARGUMENTS:
 */
      }

      /* "pysam/libcutils.pyx":307
 *                     skip_next = True
 *                 continue
 *             if not os.path.exists(arg):             # <<<<<<<<<<<<<<
 *                 raise IOError("No such file or directory: '%s'" % arg)
 *             else:
 */
      __Pyx_GetModuleGlobalName(__pyx_t_7, __pyx_n_s_os); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 307, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      __pyx_t_8 = __Pyx_PyObject_GetAttrStr(__pyx_t_7, __pyx_n_s_path); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 307, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_8);
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      __pyx_t_7 = __Pyx_PyObject_GetAttrStr(__pyx_t_8, __pyx_n_s_exists); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 307, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
      __pyx_t_8 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_7))) {
        __pyx_t_8 = PyMethod_GET_SELF(__pyx_t_7);
        if (likely(__pyx_t_8)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_7);
          __Pyx_INCREF(__pyx_t_8);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_7, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_8, __pyx_v_arg};
        __pyx_t_6 = __Pyx_PyObject_FastCall(__pyx_t_7, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
        if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 307, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_6);
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      }
      __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_t_6); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 307, __pyx_L1_error)
      __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
      __pyx_t_2 = (!__pyx_t_1);
      if (unlikely(__pyx_t_2)) {

        /* "pysam/libcutils.pyx":308
 *                 continue
 *             if not os.path.exists(arg):
 *                 raise IOError("No such file or directory: '%s'" % arg)             # <<<<<<<<<<<<<<
 *             else:
 *                 break
 */
        __pyx_t_6 = __Pyx_PyUnicode_FormatSafe(__pyx_kp_u_No_such_file_or_directory_s, __pyx_v_arg); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 308, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_6);
        __pyx_t_7 = __Pyx_PyObject_CallOneArg(__pyx_builtin_IOError, __pyx_t_6); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 308, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
        __Pyx_Raise(__pyx_t_7, 0, 0, 0);
        __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
        __PYX_ERR(0, 308, __pyx_L1_error)

        /* "pysam/libcutils.pyx":307
 *                     skip_next = True
 *                 continue
 *             if not os.path.exists(arg):             # <<<<<<<<<<<<<<
 *                 raise IOError("No such file or directory: '%s'" % arg)
 *             else:
 */
      }

      /* "pysam/libcutils.pyx":310
 *                 raise IOError("No such file or directory: '%s'" % arg)
 *             else:
 *                 break             # <<<<<<<<<<<<<<
 * 
 *     if args is None:
 */
      /*else*/ {
        goto __pyx_L7_break;
      }

      /* "pysam/libcutils.pyx":298
 *         ARGUMENTS = ['-m', '--min-shift', '-o', '--output', '--output-file', '-@', '--threads']
 *         skip_next = False
 *         for arg in args:             # <<<<<<<<<<<<<<
 *             if skip_next:
 *                 skip_next = False
 */
      __pyx_L6_continue:;
    }
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    goto __pyx_L12_for_end;
    __pyx_L7_break:;
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    goto __pyx_L12_for_end;
    __pyx_L12_for_end:;

    /* "pysam/libcutils.pyx":293
 *     '''
 * 
 *     if method == "index" and args:             # <<<<<<<<<<<<<<
 *         # We make sure that at least the first specified input file exists,
 *         # and if it doesn't we raise an IOError.
 */
  }

  /* "pysam/libcutils.pyx":312
 *                 break
 * 
 *     if args is None:             # <<<<<<<<<<<<<<
 *         args = []
 *     else:
 */
  __pyx_t_2 = (__pyx_v_args == Py_None);
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":313
 * 
 *     if args is None:
 *         args = []             # <<<<<<<<<<<<<<
 *     else:
 *         args = list(args)
 */
    __pyx_t_3 = PyList_New(0); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 313, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __Pyx_DECREF_SET(__pyx_v_args, __pyx_t_3);
    __pyx_t_3 = 0;

    /* "pysam/libcutils.pyx":312
 *                 break
 * 
 *     if args is None:             # <<<<<<<<<<<<<<
 *         args = []
 *     else:
 */
    goto __pyx_L13;
  }

  /* "pysam/libcutils.pyx":315
 *         args = []
 *     else:
 *         args = list(args)             # <<<<<<<<<<<<<<
 * 
 *     # redirect stderr to file
 */
  /*else*/ {
    __pyx_t_3 = PySequence_List(__pyx_v_args); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 315, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __Pyx_DECREF_SET(__pyx_v_args, __pyx_t_3);
    __pyx_t_3 = 0;
  }
  __pyx_L13:;

  /* "pysam/libcutils.pyx":318
 * 
 *     # redirect stderr to file
 *     stderr_h, stderr_f = tempfile.mkstemp()             # <<<<<<<<<<<<<<
 * 
 *     # redirect stdout to file
 */
  __Pyx_GetModuleGlobalName(__pyx_t_7, __pyx_n_s_tempfile); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 318, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __pyx_t_6 = __Pyx_PyObject_GetAttrStr(__pyx_t_7, __pyx_n_s_mkstemp); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 318, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_6);
  __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
  __pyx_t_7 = NULL;
  __pyx_t_9 = 0;
  #if CYTHON_UNPACK_METHODS
  if (unlikely(PyMethod_Check(__pyx_t_6))) {
    __pyx_t_7 = PyMethod_GET_SELF(__pyx_t_6);
    if (likely(__pyx_t_7)) {
      PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_6);
      __Pyx_INCREF(__pyx_t_7);
      __Pyx_INCREF(function);
      __Pyx_DECREF_SET(__pyx_t_6, function);
      __pyx_t_9 = 1;
    }
  }
  #endif
  {
    PyObject *__pyx_callargs[1] = {__pyx_t_7, };
    __pyx_t_3 = __Pyx_PyObject_FastCall(__pyx_t_6, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
    __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
    if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 318, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
  }
  if ((likely(PyTuple_CheckExact(__pyx_t_3))) || (PyList_CheckExact(__pyx_t_3))) {
    PyObject* sequence = __pyx_t_3;
    Py_ssize_t size = __Pyx_PySequence_SIZE(sequence);
    if (unlikely(size != 2)) {
      if (size > 2) __Pyx_RaiseTooManyValuesError(2);
      else if (size >= 0) __Pyx_RaiseNeedMoreValuesError(size);
      __PYX_ERR(0, 318, __pyx_L1_error)
    }
    #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    if (likely(PyTuple_CheckExact(sequence))) {
      __pyx_t_6 = PyTuple_GET_ITEM(sequence, 0); 
      __pyx_t_7 = PyTuple_GET_ITEM(sequence, 1); 
    } else {
      __pyx_t_6 = PyList_GET_ITEM(sequence, 0); 
      __pyx_t_7 = PyList_GET_ITEM(sequence, 1); 
    }
    __Pyx_INCREF(__pyx_t_6);
    __Pyx_INCREF(__pyx_t_7);
    #else
    __pyx_t_6 = PySequence_ITEM(sequence, 0); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 318, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_6);
    __pyx_t_7 = PySequence_ITEM(sequence, 1); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 318, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    #endif
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  } else {
    Py_ssize_t index = -1;
    __pyx_t_8 = PyObject_GetIter(__pyx_t_3); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 318, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_8);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    __pyx_t_10 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_8);
    index = 0; __pyx_t_6 = __pyx_t_10(__pyx_t_8); if (unlikely(!__pyx_t_6)) goto __pyx_L14_unpacking_failed;
    __Pyx_GOTREF(__pyx_t_6);
    index = 1; __pyx_t_7 = __pyx_t_10(__pyx_t_8); if (unlikely(!__pyx_t_7)) goto __pyx_L14_unpacking_failed;
    __Pyx_GOTREF(__pyx_t_7);
    if (__Pyx_IternextUnpackEndCheck(__pyx_t_10(__pyx_t_8), 2) < 0) __PYX_ERR(0, 318, __pyx_L1_error)
    __pyx_t_10 = NULL;
    __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
    goto __pyx_L15_unpacking_done;
    __pyx_L14_unpacking_failed:;
    __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
    __pyx_t_10 = NULL;
    if (__Pyx_IterFinish() == 0) __Pyx_RaiseNeedMoreValuesError(index);
    __PYX_ERR(0, 318, __pyx_L1_error)
    __pyx_L15_unpacking_done:;
  }
  __pyx_v_stderr_h = __pyx_t_6;
  __pyx_t_6 = 0;
  __pyx_v_stderr_f = __pyx_t_7;
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":321
 * 
 *     # redirect stdout to file
 *     if save_stdout:             # <<<<<<<<<<<<<<
 *         stdout_f = save_stdout
 *         stdout_h = c_open(force_bytes(stdout_f),
 */
  __pyx_t_2 = __Pyx_PyObject_IsTrue(__pyx_v_save_stdout); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 321, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":322
 *     # redirect stdout to file
 *     if save_stdout:
 *         stdout_f = save_stdout             # <<<<<<<<<<<<<<
 *         stdout_h = c_open(force_bytes(stdout_f),
 *                           O_WRONLY)
 */
    __Pyx_INCREF(__pyx_v_save_stdout);
    __pyx_v_stdout_f = __pyx_v_save_stdout;

    /* "pysam/libcutils.pyx":323
 *     if save_stdout:
 *         stdout_f = save_stdout
 *         stdout_h = c_open(force_bytes(stdout_f),             # <<<<<<<<<<<<<<
 *                           O_WRONLY)
 *         if stdout_h == -1:
 */
    __pyx_t_3 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_stdout_f, NULL); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 323, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    if (unlikely(__pyx_t_3 == Py_None)) {
      PyErr_SetString(PyExc_TypeError, "expected bytes, NoneType found");
      __PYX_ERR(0, 323, __pyx_L1_error)
    }
    __pyx_t_11 = __Pyx_PyBytes_AsString(__pyx_t_3); if (unlikely((!__pyx_t_11) && PyErr_Occurred())) __PYX_ERR(0, 323, __pyx_L1_error)

    /* "pysam/libcutils.pyx":324
 *         stdout_f = save_stdout
 *         stdout_h = c_open(force_bytes(stdout_f),
 *                           O_WRONLY)             # <<<<<<<<<<<<<<
 *         if stdout_h == -1:
 *             raise IOError("error while opening {} for writing".format(stdout_f))
 */
    __pyx_t_7 = __Pyx_PyInt_From_int(open(__pyx_t_11, O_WRONLY)); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 323, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    __pyx_v_stdout_h = __pyx_t_7;
    __pyx_t_7 = 0;

    /* "pysam/libcutils.pyx":325
 *         stdout_h = c_open(force_bytes(stdout_f),
 *                           O_WRONLY)
 *         if stdout_h == -1:             # <<<<<<<<<<<<<<
 *             raise IOError("error while opening {} for writing".format(stdout_f))
 * 
 */
    __pyx_t_2 = (__Pyx_PyInt_BoolEqObjC(__pyx_v_stdout_h, __pyx_int_neg_1, -1L, 0)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 325, __pyx_L1_error)
    if (unlikely(__pyx_t_2)) {

      /* "pysam/libcutils.pyx":326
 *                           O_WRONLY)
 *         if stdout_h == -1:
 *             raise IOError("error while opening {} for writing".format(stdout_f))             # <<<<<<<<<<<<<<
 * 
 *         samtools_set_stdout_fn(force_bytes(stdout_f))
 */
      __pyx_t_3 = __Pyx_PyObject_GetAttrStr(__pyx_kp_u_error_while_opening_for_writing, __pyx_n_s_format); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 326, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_3);
      __pyx_t_6 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_3))) {
        __pyx_t_6 = PyMethod_GET_SELF(__pyx_t_3);
        if (likely(__pyx_t_6)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_3);
          __Pyx_INCREF(__pyx_t_6);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_3, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_6, __pyx_v_stdout_f};
        __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_3, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_6); __pyx_t_6 = 0;
        if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 326, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
      }
      __pyx_t_3 = __Pyx_PyObject_CallOneArg(__pyx_builtin_IOError, __pyx_t_7); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 326, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_3);
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
      __Pyx_Raise(__pyx_t_3, 0, 0, 0);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
      __PYX_ERR(0, 326, __pyx_L1_error)

      /* "pysam/libcutils.pyx":325
 *         stdout_h = c_open(force_bytes(stdout_f),
 *                           O_WRONLY)
 *         if stdout_h == -1:             # <<<<<<<<<<<<<<
 *             raise IOError("error while opening {} for writing".format(stdout_f))
 * 
 */
    }

    /* "pysam/libcutils.pyx":328
 *             raise IOError("error while opening {} for writing".format(stdout_f))
 * 
 *         samtools_set_stdout_fn(force_bytes(stdout_f))             # <<<<<<<<<<<<<<
 *         bcftools_set_stdout_fn(force_bytes(stdout_f))
 * 
 */
    __pyx_t_3 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_stdout_f, NULL); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 328, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    if (unlikely(__pyx_t_3 == Py_None)) {
      PyErr_SetString(PyExc_TypeError, "expected bytes, NoneType found");
      __PYX_ERR(0, 328, __pyx_L1_error)
    }
    __pyx_t_12 = __Pyx_PyBytes_AsString(__pyx_t_3); if (unlikely((!__pyx_t_12) && PyErr_Occurred())) __PYX_ERR(0, 328, __pyx_L1_error)
    samtools_set_stdout_fn(__pyx_t_12);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

    /* "pysam/libcutils.pyx":329
 * 
 *         samtools_set_stdout_fn(force_bytes(stdout_f))
 *         bcftools_set_stdout_fn(force_bytes(stdout_f))             # <<<<<<<<<<<<<<
 * 
 *     elif catch_stdout:
 */
    __pyx_t_3 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_stdout_f, NULL); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 329, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    if (unlikely(__pyx_t_3 == Py_None)) {
      PyErr_SetString(PyExc_TypeError, "expected bytes, NoneType found");
      __PYX_ERR(0, 329, __pyx_L1_error)
    }
    __pyx_t_13 = __Pyx_PyBytes_AsString(__pyx_t_3); if (unlikely((!__pyx_t_13) && PyErr_Occurred())) __PYX_ERR(0, 329, __pyx_L1_error)
    bcftools_set_stdout_fn(__pyx_t_13);
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

    /* "pysam/libcutils.pyx":321
 * 
 *     # redirect stdout to file
 *     if save_stdout:             # <<<<<<<<<<<<<<
 *         stdout_f = save_stdout
 *         stdout_h = c_open(force_bytes(stdout_f),
 */
    goto __pyx_L16;
  }

  /* "pysam/libcutils.pyx":331
 *         bcftools_set_stdout_fn(force_bytes(stdout_f))
 * 
 *     elif catch_stdout:             # <<<<<<<<<<<<<<
 *         stdout_h, stdout_f = tempfile.mkstemp()
 *         MAP_STDOUT_OPTIONS = {
 */
  __pyx_t_2 = __Pyx_PyObject_IsTrue(__pyx_v_catch_stdout); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 331, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":332
 * 
 *     elif catch_stdout:
 *         stdout_h, stdout_f = tempfile.mkstemp()             # <<<<<<<<<<<<<<
 *         MAP_STDOUT_OPTIONS = {
 *         "samtools": {
 */
    __Pyx_GetModuleGlobalName(__pyx_t_7, __pyx_n_s_tempfile); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 332, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __pyx_t_6 = __Pyx_PyObject_GetAttrStr(__pyx_t_7, __pyx_n_s_mkstemp); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 332, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_6);
    __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
    __pyx_t_7 = NULL;
    __pyx_t_9 = 0;
    #if CYTHON_UNPACK_METHODS
    if (unlikely(PyMethod_Check(__pyx_t_6))) {
      __pyx_t_7 = PyMethod_GET_SELF(__pyx_t_6);
      if (likely(__pyx_t_7)) {
        PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_6);
        __Pyx_INCREF(__pyx_t_7);
        __Pyx_INCREF(function);
        __Pyx_DECREF_SET(__pyx_t_6, function);
        __pyx_t_9 = 1;
      }
    }
    #endif
    {
      PyObject *__pyx_callargs[1] = {__pyx_t_7, };
      __pyx_t_3 = __Pyx_PyObject_FastCall(__pyx_t_6, __pyx_callargs+1-__pyx_t_9, 0+__pyx_t_9);
      __Pyx_XDECREF(__pyx_t_7); __pyx_t_7 = 0;
      if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 332, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_3);
      __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
    }
    if ((likely(PyTuple_CheckExact(__pyx_t_3))) || (PyList_CheckExact(__pyx_t_3))) {
      PyObject* sequence = __pyx_t_3;
      Py_ssize_t size = __Pyx_PySequence_SIZE(sequence);
      if (unlikely(size != 2)) {
        if (size > 2) __Pyx_RaiseTooManyValuesError(2);
        else if (size >= 0) __Pyx_RaiseNeedMoreValuesError(size);
        __PYX_ERR(0, 332, __pyx_L1_error)
      }
      #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
      if (likely(PyTuple_CheckExact(sequence))) {
        __pyx_t_6 = PyTuple_GET_ITEM(sequence, 0); 
        __pyx_t_7 = PyTuple_GET_ITEM(sequence, 1); 
      } else {
        __pyx_t_6 = PyList_GET_ITEM(sequence, 0); 
        __pyx_t_7 = PyList_GET_ITEM(sequence, 1); 
      }
      __Pyx_INCREF(__pyx_t_6);
      __Pyx_INCREF(__pyx_t_7);
      #else
      __pyx_t_6 = PySequence_ITEM(sequence, 0); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 332, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_6);
      __pyx_t_7 = PySequence_ITEM(sequence, 1); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 332, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      #endif
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    } else {
      Py_ssize_t index = -1;
      __pyx_t_8 = PyObject_GetIter(__pyx_t_3); if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 332, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_8);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
      __pyx_t_10 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_8);
      index = 0; __pyx_t_6 = __pyx_t_10(__pyx_t_8); if (unlikely(!__pyx_t_6)) goto __pyx_L18_unpacking_failed;
      __Pyx_GOTREF(__pyx_t_6);
      index = 1; __pyx_t_7 = __pyx_t_10(__pyx_t_8); if (unlikely(!__pyx_t_7)) goto __pyx_L18_unpacking_failed;
      __Pyx_GOTREF(__pyx_t_7);
      if (__Pyx_IternextUnpackEndCheck(__pyx_t_10(__pyx_t_8), 2) < 0) __PYX_ERR(0, 332, __pyx_L1_error)
      __pyx_t_10 = NULL;
      __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
      goto __pyx_L19_unpacking_done;
      __pyx_L18_unpacking_failed:;
      __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
      __pyx_t_10 = NULL;
      if (__Pyx_IterFinish() == 0) __Pyx_RaiseNeedMoreValuesError(index);
      __PYX_ERR(0, 332, __pyx_L1_error)
      __pyx_L19_unpacking_done:;
    }
    __pyx_v_stdout_h = __pyx_t_6;
    __pyx_t_6 = 0;
    __pyx_v_stdout_f = __pyx_t_7;
    __pyx_t_7 = 0;

    /* "pysam/libcutils.pyx":334
 *         stdout_h, stdout_f = tempfile.mkstemp()
 *         MAP_STDOUT_OPTIONS = {
 *         "samtools": {             # <<<<<<<<<<<<<<
 *             "view": "-o {}",
 *             "mpileup": "-o {}",
 */
    __pyx_t_3 = __Pyx_PyDict_NewPresized(2); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 334, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);

    /* "pysam/libcutils.pyx":335
 *         MAP_STDOUT_OPTIONS = {
 *         "samtools": {
 *             "view": "-o {}",             # <<<<<<<<<<<<<<
 *             "mpileup": "-o {}",
 *             "depad": "-o {}",
 */
    __pyx_t_7 = __Pyx_PyDict_NewPresized(4); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 335, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    if (PyDict_SetItem(__pyx_t_7, __pyx_n_u_view, __pyx_kp_u_o_2) < 0) __PYX_ERR(0, 335, __pyx_L1_error)
    if (PyDict_SetItem(__pyx_t_7, __pyx_n_u_mpileup, __pyx_kp_u_o_2) < 0) __PYX_ERR(0, 335, __pyx_L1_error)
    if (PyDict_SetItem(__pyx_t_7, __pyx_n_u_depad, __pyx_kp_u_o_2) < 0) __PYX_ERR(0, 335, __pyx_L1_error)
    if (PyDict_SetItem(__pyx_t_7, __pyx_n_u_calmd, __pyx_kp_u_) < 0) __PYX_ERR(0, 335, __pyx_L1_error)
    if (PyDict_SetItem(__pyx_t_3, __pyx_n_u_samtools, __pyx_t_7) < 0) __PYX_ERR(0, 334, __pyx_L1_error)
    __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;

    /* "pysam/libcutils.pyx":340
 *             "calmd": "",  # uses pysam_stdout_fn
 *         },
 *             "bcftools": {}             # <<<<<<<<<<<<<<
 *         }
 * 
 */
    __pyx_t_7 = __Pyx_PyDict_NewPresized(0); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 340, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    if (PyDict_SetItem(__pyx_t_3, __pyx_n_u_bcftools, __pyx_t_7) < 0) __PYX_ERR(0, 334, __pyx_L1_error)
    __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
    __pyx_v_MAP_STDOUT_OPTIONS = ((PyObject*)__pyx_t_3);
    __pyx_t_3 = 0;

    /* "pysam/libcutils.pyx":343
 *         }
 * 
 *         stdout_option = None             # <<<<<<<<<<<<<<
 *         if collection == "bcftools":
 *             # in bcftools, most methods accept -o, the exceptions
 */
    __Pyx_INCREF(Py_None);
    __pyx_v_stdout_option = Py_None;

    /* "pysam/libcutils.pyx":344
 * 
 *         stdout_option = None
 *         if collection == "bcftools":             # <<<<<<<<<<<<<<
 *             # in bcftools, most methods accept -o, the exceptions
 *             # are below:
 */
    __pyx_t_2 = (__Pyx_PyUnicode_Equals(__pyx_v_collection, __pyx_n_u_bcftools, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 344, __pyx_L1_error)
    if (__pyx_t_2) {

      /* "pysam/libcutils.pyx":347
 *             # in bcftools, most methods accept -o, the exceptions
 *             # are below:
 *             if method not in ("index", "roh", "stats"):             # <<<<<<<<<<<<<<
 *                 stdout_option = "-o {}"
 *         elif method in MAP_STDOUT_OPTIONS[collection]:
 */
      __Pyx_INCREF(__pyx_v_method);
      __pyx_t_3 = __pyx_v_method;
      __pyx_t_1 = (__Pyx_PyUnicode_Equals(__pyx_t_3, __pyx_n_u_index, Py_NE)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 347, __pyx_L1_error)
      if (__pyx_t_1) {
      } else {
        __pyx_t_2 = __pyx_t_1;
        goto __pyx_L22_bool_binop_done;
      }
      __pyx_t_1 = (__Pyx_PyUnicode_Equals(__pyx_t_3, __pyx_n_u_roh, Py_NE)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 347, __pyx_L1_error)
      if (__pyx_t_1) {
      } else {
        __pyx_t_2 = __pyx_t_1;
        goto __pyx_L22_bool_binop_done;
      }
      __pyx_t_1 = (__Pyx_PyUnicode_Equals(__pyx_t_3, __pyx_n_u_stats, Py_NE)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 347, __pyx_L1_error)
      __pyx_t_2 = __pyx_t_1;
      __pyx_L22_bool_binop_done:;
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
      __pyx_t_1 = __pyx_t_2;
      if (__pyx_t_1) {

        /* "pysam/libcutils.pyx":348
 *             # are below:
 *             if method not in ("index", "roh", "stats"):
 *                 stdout_option = "-o {}"             # <<<<<<<<<<<<<<
 *         elif method in MAP_STDOUT_OPTIONS[collection]:
 *             # special case - samtools view -c outputs on stdout
 */
        __Pyx_INCREF(__pyx_kp_u_o_2);
        __Pyx_DECREF_SET(__pyx_v_stdout_option, __pyx_kp_u_o_2);

        /* "pysam/libcutils.pyx":347
 *             # in bcftools, most methods accept -o, the exceptions
 *             # are below:
 *             if method not in ("index", "roh", "stats"):             # <<<<<<<<<<<<<<
 *                 stdout_option = "-o {}"
 *         elif method in MAP_STDOUT_OPTIONS[collection]:
 */
      }

      /* "pysam/libcutils.pyx":344
 * 
 *         stdout_option = None
 *         if collection == "bcftools":             # <<<<<<<<<<<<<<
 *             # in bcftools, most methods accept -o, the exceptions
 *             # are below:
 */
      goto __pyx_L20;
    }

    /* "pysam/libcutils.pyx":349
 *             if method not in ("index", "roh", "stats"):
 *                 stdout_option = "-o {}"
 *         elif method in MAP_STDOUT_OPTIONS[collection]:             # <<<<<<<<<<<<<<
 *             # special case - samtools view -c outputs on stdout
 *             if not(method == "view" and "-c" in args):
 */
    __pyx_t_3 = __Pyx_PyDict_GetItem(__pyx_v_MAP_STDOUT_OPTIONS, __pyx_v_collection); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 349, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_3);
    __pyx_t_1 = (__Pyx_PySequence_ContainsTF(__pyx_v_method, __pyx_t_3, Py_EQ)); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 349, __pyx_L1_error)
    __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    if (__pyx_t_1) {

      /* "pysam/libcutils.pyx":351
 *         elif method in MAP_STDOUT_OPTIONS[collection]:
 *             # special case - samtools view -c outputs on stdout
 *             if not(method == "view" and "-c" in args):             # <<<<<<<<<<<<<<
 *                 stdout_option = MAP_STDOUT_OPTIONS[collection][method]
 * 
 */
      __pyx_t_2 = (__Pyx_PyUnicode_Equals(__pyx_v_method, __pyx_n_u_view, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 351, __pyx_L1_error)
      if (__pyx_t_2) {
      } else {
        __pyx_t_1 = __pyx_t_2;
        goto __pyx_L26_bool_binop_done;
      }
      __pyx_t_2 = (__Pyx_PySequence_ContainsTF(__pyx_kp_u_c, __pyx_v_args, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 351, __pyx_L1_error)
      __pyx_t_1 = __pyx_t_2;
      __pyx_L26_bool_binop_done:;
      __pyx_t_2 = (!__pyx_t_1);
      if (__pyx_t_2) {

        /* "pysam/libcutils.pyx":352
 *             # special case - samtools view -c outputs on stdout
 *             if not(method == "view" and "-c" in args):
 *                 stdout_option = MAP_STDOUT_OPTIONS[collection][method]             # <<<<<<<<<<<<<<
 * 
 *         if stdout_option is not None and not is_usage:
 */
        __pyx_t_3 = __Pyx_PyDict_GetItem(__pyx_v_MAP_STDOUT_OPTIONS, __pyx_v_collection); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 352, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_3);
        __pyx_t_7 = __Pyx_PyObject_GetItem(__pyx_t_3, __pyx_v_method); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 352, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
        __Pyx_DECREF_SET(__pyx_v_stdout_option, __pyx_t_7);
        __pyx_t_7 = 0;

        /* "pysam/libcutils.pyx":351
 *         elif method in MAP_STDOUT_OPTIONS[collection]:
 *             # special case - samtools view -c outputs on stdout
 *             if not(method == "view" and "-c" in args):             # <<<<<<<<<<<<<<
 *                 stdout_option = MAP_STDOUT_OPTIONS[collection][method]
 * 
 */
      }

      /* "pysam/libcutils.pyx":349
 *             if method not in ("index", "roh", "stats"):
 *                 stdout_option = "-o {}"
 *         elif method in MAP_STDOUT_OPTIONS[collection]:             # <<<<<<<<<<<<<<
 *             # special case - samtools view -c outputs on stdout
 *             if not(method == "view" and "-c" in args):
 */
    }
    __pyx_L20:;

    /* "pysam/libcutils.pyx":354
 *                 stdout_option = MAP_STDOUT_OPTIONS[collection][method]
 * 
 *         if stdout_option is not None and not is_usage:             # <<<<<<<<<<<<<<
 *             os.close(stdout_h)
 *             samtools_set_stdout_fn(force_bytes(stdout_f))
 */
    __pyx_t_1 = (__pyx_v_stdout_option != Py_None);
    if (__pyx_t_1) {
    } else {
      __pyx_t_2 = __pyx_t_1;
      goto __pyx_L29_bool_binop_done;
    }
    __pyx_t_1 = __Pyx_PyObject_IsTrue(__pyx_v_is_usage); if (unlikely((__pyx_t_1 < 0))) __PYX_ERR(0, 354, __pyx_L1_error)
    __pyx_t_14 = (!__pyx_t_1);
    __pyx_t_2 = __pyx_t_14;
    __pyx_L29_bool_binop_done:;
    if (__pyx_t_2) {

      /* "pysam/libcutils.pyx":355
 * 
 *         if stdout_option is not None and not is_usage:
 *             os.close(stdout_h)             # <<<<<<<<<<<<<<
 *             samtools_set_stdout_fn(force_bytes(stdout_f))
 *             bcftools_set_stdout_fn(force_bytes(stdout_f))
 */
      __Pyx_GetModuleGlobalName(__pyx_t_3, __pyx_n_s_os); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 355, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_3);
      __pyx_t_6 = __Pyx_PyObject_GetAttrStr(__pyx_t_3, __pyx_n_s_close); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 355, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_6);
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
      __pyx_t_3 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (unlikely(PyMethod_Check(__pyx_t_6))) {
        __pyx_t_3 = PyMethod_GET_SELF(__pyx_t_6);
        if (likely(__pyx_t_3)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_6);
          __Pyx_INCREF(__pyx_t_3);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_6, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_3, __pyx_v_stdout_h};
        __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_6, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_3); __pyx_t_3 = 0;
        if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 355, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
      }
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;

      /* "pysam/libcutils.pyx":356
 *         if stdout_option is not None and not is_usage:
 *             os.close(stdout_h)
 *             samtools_set_stdout_fn(force_bytes(stdout_f))             # <<<<<<<<<<<<<<
 *             bcftools_set_stdout_fn(force_bytes(stdout_f))
 *             args.extend(stdout_option.format(stdout_f).split(" "))
 */
      __pyx_t_7 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_stdout_f, NULL); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 356, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      if (unlikely(__pyx_t_7 == Py_None)) {
        PyErr_SetString(PyExc_TypeError, "expected bytes, NoneType found");
        __PYX_ERR(0, 356, __pyx_L1_error)
      }
      __pyx_t_12 = __Pyx_PyBytes_AsString(__pyx_t_7); if (unlikely((!__pyx_t_12) && PyErr_Occurred())) __PYX_ERR(0, 356, __pyx_L1_error)
      samtools_set_stdout_fn(__pyx_t_12);
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;

      /* "pysam/libcutils.pyx":357
 *             os.close(stdout_h)
 *             samtools_set_stdout_fn(force_bytes(stdout_f))
 *             bcftools_set_stdout_fn(force_bytes(stdout_f))             # <<<<<<<<<<<<<<
 *             args.extend(stdout_option.format(stdout_f).split(" "))
 *             stdout_h = c_open(b"/dev/null", O_WRONLY)
 */
      __pyx_t_7 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_stdout_f, NULL); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 357, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      if (unlikely(__pyx_t_7 == Py_None)) {
        PyErr_SetString(PyExc_TypeError, "expected bytes, NoneType found");
        __PYX_ERR(0, 357, __pyx_L1_error)
      }
      __pyx_t_13 = __Pyx_PyBytes_AsString(__pyx_t_7); if (unlikely((!__pyx_t_13) && PyErr_Occurred())) __PYX_ERR(0, 357, __pyx_L1_error)
      bcftools_set_stdout_fn(__pyx_t_13);
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;

      /* "pysam/libcutils.pyx":358
 *             samtools_set_stdout_fn(force_bytes(stdout_f))
 *             bcftools_set_stdout_fn(force_bytes(stdout_f))
 *             args.extend(stdout_option.format(stdout_f).split(" "))             # <<<<<<<<<<<<<<
 *             stdout_h = c_open(b"/dev/null", O_WRONLY)
 *     else:
 */
      __pyx_t_6 = __Pyx_PyObject_GetAttrStr(__pyx_v_args, __pyx_n_s_extend); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 358, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_6);
      __pyx_t_15 = __Pyx_PyObject_GetAttrStr(__pyx_v_stdout_option, __pyx_n_s_format); if (unlikely(!__pyx_t_15)) __PYX_ERR(0, 358, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_15);
      __pyx_t_16 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_15))) {
        __pyx_t_16 = PyMethod_GET_SELF(__pyx_t_15);
        if (likely(__pyx_t_16)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_15);
          __Pyx_INCREF(__pyx_t_16);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_15, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_16, __pyx_v_stdout_f};
        __pyx_t_8 = __Pyx_PyObject_FastCall(__pyx_t_15, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_16); __pyx_t_16 = 0;
        if (unlikely(!__pyx_t_8)) __PYX_ERR(0, 358, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_8);
        __Pyx_DECREF(__pyx_t_15); __pyx_t_15 = 0;
      }
      __pyx_t_15 = __Pyx_PyObject_GetAttrStr(__pyx_t_8, __pyx_n_s_split); if (unlikely(!__pyx_t_15)) __PYX_ERR(0, 358, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_15);
      __Pyx_DECREF(__pyx_t_8); __pyx_t_8 = 0;
      __pyx_t_8 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_15))) {
        __pyx_t_8 = PyMethod_GET_SELF(__pyx_t_15);
        if (likely(__pyx_t_8)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_15);
          __Pyx_INCREF(__pyx_t_8);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_15, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_8, __pyx_kp_u__11};
        __pyx_t_3 = __Pyx_PyObject_FastCall(__pyx_t_15, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_8); __pyx_t_8 = 0;
        if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 358, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_3);
        __Pyx_DECREF(__pyx_t_15); __pyx_t_15 = 0;
      }
      __pyx_t_15 = NULL;
      __pyx_t_9 = 0;
      #if CYTHON_UNPACK_METHODS
      if (likely(PyMethod_Check(__pyx_t_6))) {
        __pyx_t_15 = PyMethod_GET_SELF(__pyx_t_6);
        if (likely(__pyx_t_15)) {
          PyObject* function = PyMethod_GET_FUNCTION(__pyx_t_6);
          __Pyx_INCREF(__pyx_t_15);
          __Pyx_INCREF(function);
          __Pyx_DECREF_SET(__pyx_t_6, function);
          __pyx_t_9 = 1;
        }
      }
      #endif
      {
        PyObject *__pyx_callargs[2] = {__pyx_t_15, __pyx_t_3};
        __pyx_t_7 = __Pyx_PyObject_FastCall(__pyx_t_6, __pyx_callargs+1-__pyx_t_9, 1+__pyx_t_9);
        __Pyx_XDECREF(__pyx_t_15); __pyx_t_15 = 0;
        __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
        if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 358, __pyx_L1_error)
        __Pyx_GOTREF(__pyx_t_7);
        __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
      }
      __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;

      /* "pysam/libcutils.pyx":359
 *             bcftools_set_stdout_fn(force_bytes(stdout_f))
 *             args.extend(stdout_option.format(stdout_f).split(" "))
 *             stdout_h = c_open(b"/dev/null", O_WRONLY)             # <<<<<<<<<<<<<<
 *     else:
 *         samtools_set_stdout_fn("-")
 */
      __pyx_t_7 = __Pyx_PyInt_From_int(open(((char const *)"/dev/null"), O_WRONLY)); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 359, __pyx_L1_error)
      __Pyx_GOTREF(__pyx_t_7);
      __Pyx_DECREF_SET(__pyx_v_stdout_h, __pyx_t_7);
      __pyx_t_7 = 0;

      /* "pysam/libcutils.pyx":354
 *                 stdout_option = MAP_STDOUT_OPTIONS[collection][method]
 * 
 *         if stdout_option is not None and not is_usage:             # <<<<<<<<<<<<<<
 *             os.close(stdout_h)
 *             samtools_set_stdout_fn(force_bytes(stdout_f))
 */
    }

    /* "pysam/libcutils.pyx":331
 *         bcftools_set_stdout_fn(force_bytes(stdout_f))
 * 
 *     elif catch_stdout:             # <<<<<<<<<<<<<<
 *         stdout_h, stdout_f = tempfile.mkstemp()
 *         MAP_STDOUT_OPTIONS = {
 */
    goto __pyx_L16;
  }

  /* "pysam/libcutils.pyx":361
 *             stdout_h = c_open(b"/dev/null", O_WRONLY)
 *     else:
 *         samtools_set_stdout_fn("-")             # <<<<<<<<<<<<<<
 *         bcftools_set_stdout_fn("-")
 *         stdout_h = c_open(b"/dev/null", O_WRONLY)
 */
  /*else*/ {
    samtools_set_stdout_fn(((char const *)"-"));

    /* "pysam/libcutils.pyx":362
 *     else:
 *         samtools_set_stdout_fn("-")
 *         bcftools_set_stdout_fn("-")             # <<<<<<<<<<<<<<
 *         stdout_h = c_open(b"/dev/null", O_WRONLY)
 * 
 */
    bcftools_set_stdout_fn(((char const *)"-"));

    /* "pysam/libcutils.pyx":363
 *         samtools_set_stdout_fn("-")
 *         bcftools_set_stdout_fn("-")
 *         stdout_h = c_open(b"/dev/null", O_WRONLY)             # <<<<<<<<<<<<<<
 * 
 *     # setup the function call to samtools/bcftools main
 */
    __pyx_t_7 = __Pyx_PyInt_From_int(open(((char const *)"/dev/null"), O_WRONLY)); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 363, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __pyx_v_stdout_h = __pyx_t_7;
    __pyx_t_7 = 0;
  }
  __pyx_L16:;

  /* "pysam/libcutils.pyx":368
 *     cdef char ** cargs
 *     cdef int i, n, retval, l
 *     n = len(args)             # <<<<<<<<<<<<<<
 *     method = force_bytes(method)
 *     collection = force_bytes(collection)
 */
  __pyx_t_4 = PyObject_Length(__pyx_v_args); if (unlikely(__pyx_t_4 == ((Py_ssize_t)-1))) __PYX_ERR(0, 368, __pyx_L1_error)
  __pyx_v_n = __pyx_t_4;

  /* "pysam/libcutils.pyx":369
 *     cdef int i, n, retval, l
 *     n = len(args)
 *     method = force_bytes(method)             # <<<<<<<<<<<<<<
 *     collection = force_bytes(collection)
 *     args = [force_bytes(a) for a in args]
 */
  __pyx_t_7 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_method, NULL); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 369, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __Pyx_DECREF_SET(__pyx_v_method, __pyx_t_7);
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":370
 *     n = len(args)
 *     method = force_bytes(method)
 *     collection = force_bytes(collection)             # <<<<<<<<<<<<<<
 *     args = [force_bytes(a) for a in args]
 * 
 */
  __pyx_t_7 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_v_collection, NULL); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 370, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __Pyx_DECREF_SET(__pyx_v_collection, __pyx_t_7);
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":371
 *     method = force_bytes(method)
 *     collection = force_bytes(collection)
 *     args = [force_bytes(a) for a in args]             # <<<<<<<<<<<<<<
 * 
 *     # allocate two more for first (dummy) argument (contains command)
 */
  { /* enter inner scope */
    __pyx_t_7 = PyList_New(0); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 371, __pyx_L33_error)
    __Pyx_GOTREF(__pyx_t_7);
    if (likely(PyList_CheckExact(__pyx_v_args)) || PyTuple_CheckExact(__pyx_v_args)) {
      __pyx_t_6 = __pyx_v_args; __Pyx_INCREF(__pyx_t_6); __pyx_t_4 = 0;
      __pyx_t_5 = NULL;
    } else {
      __pyx_t_4 = -1; __pyx_t_6 = PyObject_GetIter(__pyx_v_args); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 371, __pyx_L33_error)
      __Pyx_GOTREF(__pyx_t_6);
      __pyx_t_5 = __Pyx_PyObject_GetIterNextFunc(__pyx_t_6); if (unlikely(!__pyx_t_5)) __PYX_ERR(0, 371, __pyx_L33_error)
    }
    for (;;) {
      if (likely(!__pyx_t_5)) {
        if (likely(PyList_CheckExact(__pyx_t_6))) {
          if (__pyx_t_4 >= PyList_GET_SIZE(__pyx_t_6)) break;
          #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
          __pyx_t_3 = PyList_GET_ITEM(__pyx_t_6, __pyx_t_4); __Pyx_INCREF(__pyx_t_3); __pyx_t_4++; if (unlikely((0 < 0))) __PYX_ERR(0, 371, __pyx_L33_error)
          #else
          __pyx_t_3 = PySequence_ITEM(__pyx_t_6, __pyx_t_4); __pyx_t_4++; if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 371, __pyx_L33_error)
          __Pyx_GOTREF(__pyx_t_3);
          #endif
        } else {
          if (__pyx_t_4 >= PyTuple_GET_SIZE(__pyx_t_6)) break;
          #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
          __pyx_t_3 = PyTuple_GET_ITEM(__pyx_t_6, __pyx_t_4); __Pyx_INCREF(__pyx_t_3); __pyx_t_4++; if (unlikely((0 < 0))) __PYX_ERR(0, 371, __pyx_L33_error)
          #else
          __pyx_t_3 = PySequence_ITEM(__pyx_t_6, __pyx_t_4); __pyx_t_4++; if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 371, __pyx_L33_error)
          __Pyx_GOTREF(__pyx_t_3);
          #endif
        }
      } else {
        __pyx_t_3 = __pyx_t_5(__pyx_t_6);
        if (unlikely(!__pyx_t_3)) {
          PyObject* exc_type = PyErr_Occurred();
          if (exc_type) {
            if (likely(__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration))) PyErr_Clear();
            else __PYX_ERR(0, 371, __pyx_L33_error)
          }
          break;
        }
        __Pyx_GOTREF(__pyx_t_3);
      }
      __Pyx_XDECREF_SET(__pyx_8genexpr2__pyx_v_a, __pyx_t_3);
      __pyx_t_3 = 0;
      __pyx_t_3 = __pyx_f_5pysam_9libcutils_force_bytes(__pyx_8genexpr2__pyx_v_a, NULL); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 371, __pyx_L33_error)
      __Pyx_GOTREF(__pyx_t_3);
      if (unlikely(__Pyx_ListComp_Append(__pyx_t_7, (PyObject*)__pyx_t_3))) __PYX_ERR(0, 371, __pyx_L33_error)
      __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
    }
    __Pyx_DECREF(__pyx_t_6); __pyx_t_6 = 0;
    __Pyx_XDECREF(__pyx_8genexpr2__pyx_v_a); __pyx_8genexpr2__pyx_v_a = 0;
    goto __pyx_L37_exit_scope;
    __pyx_L33_error:;
    __Pyx_XDECREF(__pyx_8genexpr2__pyx_v_a); __pyx_8genexpr2__pyx_v_a = 0;
    goto __pyx_L1_error;
    __pyx_L37_exit_scope:;
  } /* exit inner scope */
  __Pyx_DECREF_SET(__pyx_v_args, __pyx_t_7);
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":374
 * 
 *     # allocate two more for first (dummy) argument (contains command)
 *     cdef int extra_args = 0             # <<<<<<<<<<<<<<
 *     if method == b"index":
 *         extra_args = 1
 */
  __pyx_v_extra_args = 0;

  /* "pysam/libcutils.pyx":375
 *     # allocate two more for first (dummy) argument (contains command)
 *     cdef int extra_args = 0
 *     if method == b"index":             # <<<<<<<<<<<<<<
 *         extra_args = 1
 *     # add extra arguments for commands accepting optional arguments
 */
  __pyx_t_2 = (__Pyx_PyBytes_Equals(__pyx_v_method, __pyx_n_b_index, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 375, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":376
 *     cdef int extra_args = 0
 *     if method == b"index":
 *         extra_args = 1             # <<<<<<<<<<<<<<
 *     # add extra arguments for commands accepting optional arguments
 *     # such as 'samtools index x.bam [out.index]'
 */
    __pyx_v_extra_args = 1;

    /* "pysam/libcutils.pyx":375
 *     # allocate two more for first (dummy) argument (contains command)
 *     cdef int extra_args = 0
 *     if method == b"index":             # <<<<<<<<<<<<<<
 *         extra_args = 1
 *     # add extra arguments for commands accepting optional arguments
 */
  }

  /* "pysam/libcutils.pyx":379
 *     # add extra arguments for commands accepting optional arguments
 *     # such as 'samtools index x.bam [out.index]'
 *     cargs = <char**>calloc(n + 2 + extra_args, sizeof(char *))             # <<<<<<<<<<<<<<
 *     cargs[0] = collection
 *     cargs[1] = method
 */
  __pyx_v_cargs = ((char **)calloc(((__pyx_v_n + 2) + __pyx_v_extra_args), (sizeof(char *))));

  /* "pysam/libcutils.pyx":380
 *     # such as 'samtools index x.bam [out.index]'
 *     cargs = <char**>calloc(n + 2 + extra_args, sizeof(char *))
 *     cargs[0] = collection             # <<<<<<<<<<<<<<
 *     cargs[1] = method
 * 
 */
  __pyx_t_17 = __Pyx_PyObject_AsWritableString(__pyx_v_collection); if (unlikely((!__pyx_t_17) && PyErr_Occurred())) __PYX_ERR(0, 380, __pyx_L1_error)
  (__pyx_v_cargs[0]) = __pyx_t_17;

  /* "pysam/libcutils.pyx":381
 *     cargs = <char**>calloc(n + 2 + extra_args, sizeof(char *))
 *     cargs[0] = collection
 *     cargs[1] = method             # <<<<<<<<<<<<<<
 * 
 *     # create copies of strings - getopt for long options permutes
 */
  __pyx_t_17 = __Pyx_PyObject_AsWritableString(__pyx_v_method); if (unlikely((!__pyx_t_17) && PyErr_Occurred())) __PYX_ERR(0, 381, __pyx_L1_error)
  (__pyx_v_cargs[1]) = __pyx_t_17;

  /* "pysam/libcutils.pyx":385
 *     # create copies of strings - getopt for long options permutes
 *     # arguments
 *     for i from 0 <= i < n:             # <<<<<<<<<<<<<<
 *         l = len(args[i])
 *         cargs[i + 2] = <char *>calloc(l + 1, sizeof(char))
 */
  __pyx_t_9 = __pyx_v_n;
  for (__pyx_v_i = 0; __pyx_v_i < __pyx_t_9; __pyx_v_i++) {

    /* "pysam/libcutils.pyx":386
 *     # arguments
 *     for i from 0 <= i < n:
 *         l = len(args[i])             # <<<<<<<<<<<<<<
 *         cargs[i + 2] = <char *>calloc(l + 1, sizeof(char))
 *         strncpy(cargs[i + 2], args[i], l)
 */
    __pyx_t_7 = __Pyx_GetItemInt(__pyx_v_args, __pyx_v_i, int, 1, __Pyx_PyInt_From_int, 0, 1, 1); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 386, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __pyx_t_4 = PyObject_Length(__pyx_t_7); if (unlikely(__pyx_t_4 == ((Py_ssize_t)-1))) __PYX_ERR(0, 386, __pyx_L1_error)
    __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
    __pyx_v_l = __pyx_t_4;

    /* "pysam/libcutils.pyx":387
 *     for i from 0 <= i < n:
 *         l = len(args[i])
 *         cargs[i + 2] = <char *>calloc(l + 1, sizeof(char))             # <<<<<<<<<<<<<<
 *         strncpy(cargs[i + 2], args[i], l)
 * 
 */
    (__pyx_v_cargs[(__pyx_v_i + 2)]) = ((char *)calloc((__pyx_v_l + 1), (sizeof(char))));

    /* "pysam/libcutils.pyx":388
 *         l = len(args[i])
 *         cargs[i + 2] = <char *>calloc(l + 1, sizeof(char))
 *         strncpy(cargs[i + 2], args[i], l)             # <<<<<<<<<<<<<<
 * 
 *     # call samtools/bcftools
 */
    __pyx_t_7 = __Pyx_GetItemInt(__pyx_v_args, __pyx_v_i, int, 1, __Pyx_PyInt_From_int, 0, 1, 1); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 388, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __pyx_t_18 = __Pyx_PyObject_AsString(__pyx_t_7); if (unlikely((!__pyx_t_18) && PyErr_Occurred())) __PYX_ERR(0, 388, __pyx_L1_error)
    (void)(strncpy((__pyx_v_cargs[(__pyx_v_i + 2)]), __pyx_t_18, __pyx_v_l));
    __Pyx_DECREF(__pyx_t_7); __pyx_t_7 = 0;
  }

  /* "pysam/libcutils.pyx":391
 * 
 *     # call samtools/bcftools
 *     if collection == b"samtools":             # <<<<<<<<<<<<<<
 *         samtools_set_stdout(stdout_h)
 *         samtools_set_stderr(stderr_h)
 */
  __pyx_t_2 = (__Pyx_PyBytes_Equals(__pyx_v_collection, __pyx_n_b_samtools, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 391, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":392
 *     # call samtools/bcftools
 *     if collection == b"samtools":
 *         samtools_set_stdout(stdout_h)             # <<<<<<<<<<<<<<
 *         samtools_set_stderr(stderr_h)
 *         retval = samtools_dispatch(n + 2, cargs)
 */
    __pyx_t_9 = __Pyx_PyInt_As_int(__pyx_v_stdout_h); if (unlikely((__pyx_t_9 == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 392, __pyx_L1_error)
    samtools_set_stdout(__pyx_t_9);

    /* "pysam/libcutils.pyx":393
 *     if collection == b"samtools":
 *         samtools_set_stdout(stdout_h)
 *         samtools_set_stderr(stderr_h)             # <<<<<<<<<<<<<<
 *         retval = samtools_dispatch(n + 2, cargs)
 *         samtools_close_stdout()
 */
    __pyx_t_9 = __Pyx_PyInt_As_int(__pyx_v_stderr_h); if (unlikely((__pyx_t_9 == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 393, __pyx_L1_error)
    samtools_set_stderr(__pyx_t_9);

    /* "pysam/libcutils.pyx":394
 *         samtools_set_stdout(stdout_h)
 *         samtools_set_stderr(stderr_h)
 *         retval = samtools_dispatch(n + 2, cargs)             # <<<<<<<<<<<<<<
 *         samtools_close_stdout()
 *         samtools_close_stderr()
 */
    __pyx_v_retval = samtools_dispatch((__pyx_v_n + 2), __pyx_v_cargs);

    /* "pysam/libcutils.pyx":395
 *         samtools_set_stderr(stderr_h)
 *         retval = samtools_dispatch(n + 2, cargs)
 *         samtools_close_stdout()             # <<<<<<<<<<<<<<
 *         samtools_close_stderr()
 *     elif collection == b"bcftools":
 */
    samtools_close_stdout();

    /* "pysam/libcutils.pyx":396
 *         retval = samtools_dispatch(n + 2, cargs)
 *         samtools_close_stdout()
 *         samtools_close_stderr()             # <<<<<<<<<<<<<<
 *     elif collection == b"bcftools":
 *         bcftools_set_stdout(stdout_h)
 */
    samtools_close_stderr();

    /* "pysam/libcutils.pyx":391
 * 
 *     # call samtools/bcftools
 *     if collection == b"samtools":             # <<<<<<<<<<<<<<
 *         samtools_set_stdout(stdout_h)
 *         samtools_set_stderr(stderr_h)
 */
    goto __pyx_L41;
  }

  /* "pysam/libcutils.pyx":397
 *         samtools_close_stdout()
 *         samtools_close_stderr()
 *     elif collection == b"bcftools":             # <<<<<<<<<<<<<<
 *         bcftools_set_stdout(stdout_h)
 *         bcftools_set_stderr(stderr_h)
 */
  __pyx_t_2 = (__Pyx_PyBytes_Equals(__pyx_v_collection, __pyx_n_b_bcftools, Py_EQ)); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 397, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":398
 *         samtools_close_stderr()
 *     elif collection == b"bcftools":
 *         bcftools_set_stdout(stdout_h)             # <<<<<<<<<<<<<<
 *         bcftools_set_stderr(stderr_h)
 *         retval = bcftools_dispatch(n + 2, cargs)
 */
    __pyx_t_9 = __Pyx_PyInt_As_int(__pyx_v_stdout_h); if (unlikely((__pyx_t_9 == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 398, __pyx_L1_error)
    bcftools_set_stdout(__pyx_t_9);

    /* "pysam/libcutils.pyx":399
 *     elif collection == b"bcftools":
 *         bcftools_set_stdout(stdout_h)
 *         bcftools_set_stderr(stderr_h)             # <<<<<<<<<<<<<<
 *         retval = bcftools_dispatch(n + 2, cargs)
 *         bcftools_close_stdout()
 */
    __pyx_t_9 = __Pyx_PyInt_As_int(__pyx_v_stderr_h); if (unlikely((__pyx_t_9 == (int)-1) && PyErr_Occurred())) __PYX_ERR(0, 399, __pyx_L1_error)
    bcftools_set_stderr(__pyx_t_9);

    /* "pysam/libcutils.pyx":400
 *         bcftools_set_stdout(stdout_h)
 *         bcftools_set_stderr(stderr_h)
 *         retval = bcftools_dispatch(n + 2, cargs)             # <<<<<<<<<<<<<<
 *         bcftools_close_stdout()
 *         bcftools_close_stderr()
 */
    __pyx_v_retval = bcftools_dispatch((__pyx_v_n + 2), __pyx_v_cargs);

    /* "pysam/libcutils.pyx":401
 *         bcftools_set_stderr(stderr_h)
 *         retval = bcftools_dispatch(n + 2, cargs)
 *         bcftools_close_stdout()             # <<<<<<<<<<<<<<
 *         bcftools_close_stderr()
 *     else:
 */
    bcftools_close_stdout();

    /* "pysam/libcutils.pyx":402
 *         retval = bcftools_dispatch(n + 2, cargs)
 *         bcftools_close_stdout()
 *         bcftools_close_stderr()             # <<<<<<<<<<<<<<
 *     else:
 *         # unknown -- just return a Unix shell's "command not found" exit status
 */
    bcftools_close_stderr();

    /* "pysam/libcutils.pyx":397
 *         samtools_close_stdout()
 *         samtools_close_stderr()
 *     elif collection == b"bcftools":             # <<<<<<<<<<<<<<
 *         bcftools_set_stdout(stdout_h)
 *         bcftools_set_stderr(stderr_h)
 */
    goto __pyx_L41;
  }

  /* "pysam/libcutils.pyx":405
 *     else:
 *         # unknown -- just return a Unix shell's "command not found" exit status
 *         retval = 127             # <<<<<<<<<<<<<<
 * 
 *     for i from 0 <= i < n:
 */
  /*else*/ {
    __pyx_v_retval = 0x7F;
  }
  __pyx_L41:;

  /* "pysam/libcutils.pyx":407
 *         retval = 127
 * 
 *     for i from 0 <= i < n:             # <<<<<<<<<<<<<<
 *         free(cargs[i + 2])
 *     free(cargs)
 */
  __pyx_t_9 = __pyx_v_n;
  for (__pyx_v_i = 0; __pyx_v_i < __pyx_t_9; __pyx_v_i++) {

    /* "pysam/libcutils.pyx":408
 * 
 *     for i from 0 <= i < n:
 *         free(cargs[i + 2])             # <<<<<<<<<<<<<<
 *     free(cargs)
 * 
 */
    free((__pyx_v_cargs[(__pyx_v_i + 2)]));
  }

  /* "pysam/libcutils.pyx":409
 *     for i from 0 <= i < n:
 *         free(cargs[i + 2])
 *     free(cargs)             # <<<<<<<<<<<<<<
 * 
 *     # get error messages
 */
  free(__pyx_v_cargs);

  /* "pysam/libcutils.pyx":412
 * 
 *     # get error messages
 *     def _collect(fn):             # <<<<<<<<<<<<<<
 *         out = []
 *         try:
 */
  __pyx_t_7 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_15_pysam_dispatch_1_collect, 0, __pyx_n_s_pysam_dispatch_locals__collect, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__13)); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 412, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __pyx_v__collect = __pyx_t_7;
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":425
 *         return out
 * 
 *     out_stderr = _collect(stderr_f)             # <<<<<<<<<<<<<<
 *     if save_stdout:
 *         out_stdout = None
 */
  __pyx_t_7 = __pyx_pf_5pysam_9libcutils_15_pysam_dispatch__collect(__pyx_v__collect, __pyx_v_stderr_f); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 425, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __pyx_v_out_stderr = __pyx_t_7;
  __pyx_t_7 = 0;

  /* "pysam/libcutils.pyx":426
 * 
 *     out_stderr = _collect(stderr_f)
 *     if save_stdout:             # <<<<<<<<<<<<<<
 *         out_stdout = None
 *     elif catch_stdout:
 */
  __pyx_t_2 = __Pyx_PyObject_IsTrue(__pyx_v_save_stdout); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 426, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":427
 *     out_stderr = _collect(stderr_f)
 *     if save_stdout:
 *         out_stdout = None             # <<<<<<<<<<<<<<
 *     elif catch_stdout:
 *         out_stdout = _collect(stdout_f)
 */
    __Pyx_INCREF(Py_None);
    __pyx_v_out_stdout = Py_None;

    /* "pysam/libcutils.pyx":426
 * 
 *     out_stderr = _collect(stderr_f)
 *     if save_stdout:             # <<<<<<<<<<<<<<
 *         out_stdout = None
 *     elif catch_stdout:
 */
    goto __pyx_L44;
  }

  /* "pysam/libcutils.pyx":428
 *     if save_stdout:
 *         out_stdout = None
 *     elif catch_stdout:             # <<<<<<<<<<<<<<
 *         out_stdout = _collect(stdout_f)
 *     else:
 */
  __pyx_t_2 = __Pyx_PyObject_IsTrue(__pyx_v_catch_stdout); if (unlikely((__pyx_t_2 < 0))) __PYX_ERR(0, 428, __pyx_L1_error)
  if (__pyx_t_2) {

    /* "pysam/libcutils.pyx":429
 *         out_stdout = None
 *     elif catch_stdout:
 *         out_stdout = _collect(stdout_f)             # <<<<<<<<<<<<<<
 *     else:
 *         out_stdout = None
 */
    if (unlikely(!__pyx_v_stdout_f)) { __Pyx_RaiseUnboundLocalError("stdout_f"); __PYX_ERR(0, 429, __pyx_L1_error) }
    __pyx_t_7 = __pyx_pf_5pysam_9libcutils_15_pysam_dispatch__collect(__pyx_v__collect, __pyx_v_stdout_f); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 429, __pyx_L1_error)
    __Pyx_GOTREF(__pyx_t_7);
    __pyx_v_out_stdout = __pyx_t_7;
    __pyx_t_7 = 0;

    /* "pysam/libcutils.pyx":428
 *     if save_stdout:
 *         out_stdout = None
 *     elif catch_stdout:             # <<<<<<<<<<<<<<
 *         out_stdout = _collect(stdout_f)
 *     else:
 */
    goto __pyx_L44;
  }

  /* "pysam/libcutils.pyx":431
 *         out_stdout = _collect(stdout_f)
 *     else:
 *         out_stdout = None             # <<<<<<<<<<<<<<
 * 
 *     return retval, out_stderr, out_stdout
 */
  /*else*/ {
    __Pyx_INCREF(Py_None);
    __pyx_v_out_stdout = Py_None;
  }
  __pyx_L44:;

  /* "pysam/libcutils.pyx":433
 *         out_stdout = None
 * 
 *     return retval, out_stderr, out_stdout             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_XDECREF(__pyx_r);
  __pyx_t_7 = __Pyx_PyInt_From_int(__pyx_v_retval); if (unlikely(!__pyx_t_7)) __PYX_ERR(0, 433, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_7);
  __pyx_t_6 = PyTuple_New(3); if (unlikely(!__pyx_t_6)) __PYX_ERR(0, 433, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_6);
  __Pyx_GIVEREF(__pyx_t_7);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_6, 0, __pyx_t_7)) __PYX_ERR(0, 433, __pyx_L1_error);
  __Pyx_INCREF(__pyx_v_out_stderr);
  __Pyx_GIVEREF(__pyx_v_out_stderr);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_6, 1, __pyx_v_out_stderr)) __PYX_ERR(0, 433, __pyx_L1_error);
  __Pyx_INCREF(__pyx_v_out_stdout);
  __Pyx_GIVEREF(__pyx_v_out_stdout);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_6, 2, __pyx_v_out_stdout)) __PYX_ERR(0, 433, __pyx_L1_error);
  __pyx_t_7 = 0;
  __pyx_r = __pyx_t_6;
  __pyx_t_6 = 0;
  goto __pyx_L0;

  /* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */

  /* function exit code */
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_6);
  __Pyx_XDECREF(__pyx_t_7);
  __Pyx_XDECREF(__pyx_t_8);
  __Pyx_XDECREF(__pyx_t_15);
  __Pyx_XDECREF(__pyx_t_16);
  __Pyx_AddTraceback("pysam.libcutils._pysam_dispatch", __pyx_clineno, __pyx_lineno, __pyx_filename);
  __pyx_r = NULL;
  __pyx_L0:;
  __Pyx_XDECREF(__pyx_v_ARGUMENTS);
  __Pyx_XDECREF(__pyx_v_arg);
  __Pyx_XDECREF(__pyx_v_stderr_h);
  __Pyx_XDECREF(__pyx_v_stderr_f);
  __Pyx_XDECREF(__pyx_v_stdout_f);
  __Pyx_XDECREF(__pyx_v_stdout_h);
  __Pyx_XDECREF(__pyx_v_MAP_STDOUT_OPTIONS);
  __Pyx_XDECREF(__pyx_v_stdout_option);
  __Pyx_XDECREF(__pyx_v__collect);
  __Pyx_XDECREF(__pyx_v_out_stderr);
  __Pyx_XDECREF(__pyx_v_out_stdout);
  __Pyx_XDECREF(__pyx_8genexpr2__pyx_v_a);
  __Pyx_XDECREF(__pyx_v_collection);
  __Pyx_XDECREF(__pyx_v_method);
  __Pyx_XDECREF(__pyx_v_args);
  __Pyx_XGIVEREF(__pyx_r);
  __Pyx_RefNannyFinishContext();
  return __pyx_r;
}

static PyMethodDef __pyx_methods[] = {
  {0, 0, 0, 0}
};
#ifndef CYTHON_SMALL_CODE
#if defined(__clang__)
    #define CYTHON_SMALL_CODE
#elif defined(__GNUC__) && (__GNUC__ > 4 || (__GNUC__ == 4 && __GNUC_MINOR__ >= 3))
    #define CYTHON_SMALL_CODE __attribute__((cold))
#else
    #define CYTHON_SMALL_CODE
#endif
#endif
/* #### Code section: pystring_table ### */

static int __Pyx_CreateStringTabAndInitStrings(void) {
  __Pyx_StringTabEntry __pyx_string_tab[] = {
    {&__pyx_kp_u_, __pyx_k_, sizeof(__pyx_k_), 0, 1, 0, 0},
    {&__pyx_n_s_ARGUMENTS, __pyx_k_ARGUMENTS, sizeof(__pyx_k_ARGUMENTS), 0, 0, 1, 1},
    {&__pyx_kp_u_Argument_must_be_string_bytes_or, __pyx_k_Argument_must_be_string_bytes_or, sizeof(__pyx_k_Argument_must_be_string_bytes_or), 0, 1, 0, 0},
    {&__pyx_n_u_B, __pyx_k_B, sizeof(__pyx_k_B), 0, 1, 0, 1},
    {&__pyx_n_s_IOError, __pyx_k_IOError, sizeof(__pyx_k_IOError), 0, 0, 1, 1},
    {&__pyx_n_s_MAP_STDOUT_OPTIONS, __pyx_k_MAP_STDOUT_OPTIONS, sizeof(__pyx_k_MAP_STDOUT_OPTIONS), 0, 0, 1, 1},
    {&__pyx_n_s_MemoryError, __pyx_k_MemoryError, sizeof(__pyx_k_MemoryError), 0, 0, 1, 1},
    {&__pyx_kp_u_No_such_file_or_directory_s, __pyx_k_No_such_file_or_directory_s, sizeof(__pyx_k_No_such_file_or_directory_s), 0, 1, 0, 0},
    {&__pyx_n_s_OverflowError, __pyx_k_OverflowError, sizeof(__pyx_k_OverflowError), 0, 0, 1, 1},
    {&__pyx_n_s_TypeError, __pyx_k_TypeError, sizeof(__pyx_k_TypeError), 0, 0, 1, 1},
    {&__pyx_n_s_UnicodeDecodeError, __pyx_k_UnicodeDecodeError, sizeof(__pyx_k_UnicodeDecodeError), 0, 0, 1, 1},
    {&__pyx_n_s_ValueError, __pyx_k_ValueError, sizeof(__pyx_k_ValueError), 0, 0, 1, 1},
    {&__pyx_kp_u__10, __pyx_k__10, sizeof(__pyx_k__10), 0, 1, 0, 0},
    {&__pyx_kp_u__11, __pyx_k__11, sizeof(__pyx_k__11), 0, 1, 0, 0},
    {&__pyx_n_s__14, __pyx_k__14, sizeof(__pyx_k__14), 0, 0, 1, 1},
    {&__pyx_kp_u__15, __pyx_k__15, sizeof(__pyx_k__15), 0, 1, 0, 0},
    {&__pyx_n_s__33, __pyx_k__33, sizeof(__pyx_k__33), 0, 0, 1, 1},
    {&__pyx_kp_u__7, __pyx_k__7, sizeof(__pyx_k__7), 0, 1, 0, 0},
    {&__pyx_kp_u__8, __pyx_k__8, sizeof(__pyx_k__8), 0, 1, 0, 0},
    {&__pyx_n_s_a, __pyx_k_a, sizeof(__pyx_k_a), 0, 0, 1, 1},
    {&__pyx_n_s_all, __pyx_k_all, sizeof(__pyx_k_all), 0, 0, 1, 1},
    {&__pyx_n_s_arg, __pyx_k_arg, sizeof(__pyx_k_arg), 0, 0, 1, 1},
    {&__pyx_n_s_args, __pyx_k_args, sizeof(__pyx_k_args), 0, 0, 1, 1},
    {&__pyx_n_s_array_to_qualitystring, __pyx_k_array_to_qualitystring, sizeof(__pyx_k_array_to_qualitystring), 0, 0, 1, 1},
    {&__pyx_n_u_array_to_qualitystring, __pyx_k_array_to_qualitystring, sizeof(__pyx_k_array_to_qualitystring), 0, 1, 0, 1},
    {&__pyx_n_u_ascii, __pyx_k_ascii, sizeof(__pyx_k_ascii), 0, 1, 0, 1},
    {&__pyx_n_s_asyncio_coroutines, __pyx_k_asyncio_coroutines, sizeof(__pyx_k_asyncio_coroutines), 0, 0, 1, 1},
    {&__pyx_n_b_bcftools, __pyx_k_bcftools, sizeof(__pyx_k_bcftools), 0, 0, 0, 1},
    {&__pyx_n_u_bcftools, __pyx_k_bcftools, sizeof(__pyx_k_bcftools), 0, 1, 0, 1},
    {&__pyx_kp_u_c, __pyx_k_c, sizeof(__pyx_k_c), 0, 1, 0, 0},
    {&__pyx_n_u_calmd, __pyx_k_calmd, sizeof(__pyx_k_calmd), 0, 1, 0, 1},
    {&__pyx_n_s_cargs, __pyx_k_cargs, sizeof(__pyx_k_cargs), 0, 0, 1, 1},
    {&__pyx_n_s_catch_stdout, __pyx_k_catch_stdout, sizeof(__pyx_k_catch_stdout), 0, 0, 1, 1},
    {&__pyx_n_s_chr, __pyx_k_chr, sizeof(__pyx_k_chr), 0, 0, 1, 1},
    {&__pyx_n_s_class_getitem, __pyx_k_class_getitem, sizeof(__pyx_k_class_getitem), 0, 0, 1, 1},
    {&__pyx_n_s_cline_in_traceback, __pyx_k_cline_in_traceback, sizeof(__pyx_k_cline_in_traceback), 0, 0, 1, 1},
    {&__pyx_n_s_close, __pyx_k_close, sizeof(__pyx_k_close), 0, 0, 1, 1},
    {&__pyx_n_s_codecs, __pyx_k_codecs, sizeof(__pyx_k_codecs), 0, 0, 1, 1},
    {&__pyx_n_s_collect, __pyx_k_collect, sizeof(__pyx_k_collect), 0, 0, 1, 1},
    {&__pyx_n_s_collection, __pyx_k_collection, sizeof(__pyx_k_collection), 0, 0, 1, 1},
    {&__pyx_n_s_contextlib, __pyx_k_contextlib, sizeof(__pyx_k_contextlib), 0, 0, 1, 1},
    {&__pyx_n_s_contextmanager, __pyx_k_contextmanager, sizeof(__pyx_k_contextmanager), 0, 0, 1, 1},
    {&__pyx_n_s_contig, __pyx_k_contig, sizeof(__pyx_k_contig), 0, 0, 1, 1},
    {&__pyx_kp_u_contig_and_reference_should_not, __pyx_k_contig_and_reference_should_not, sizeof(__pyx_k_contig_and_reference_should_not), 0, 1, 0, 0},
    {&__pyx_kp_u_contig_reference_and_region_shou, __pyx_k_contig_reference_and_region_shou, sizeof(__pyx_k_contig_reference_and_region_shou), 0, 1, 0, 0},
    {&__pyx_n_s_decode, __pyx_k_decode, sizeof(__pyx_k_decode), 0, 0, 1, 1},
    {&__pyx_n_u_depad, __pyx_k_depad, sizeof(__pyx_k_depad), 0, 1, 0, 1},
    {&__pyx_n_s_encode, __pyx_k_encode, sizeof(__pyx_k_encode), 0, 0, 1, 1},
    {&__pyx_n_s_end, __pyx_k_end, sizeof(__pyx_k_end), 0, 0, 1, 1},
    {&__pyx_n_s_enter, __pyx_k_enter, sizeof(__pyx_k_enter), 0, 0, 1, 1},
    {&__pyx_kp_u_error_while_opening_for_writing, __pyx_k_error_while_opening_for_writing, sizeof(__pyx_k_error_while_opening_for_writing), 0, 1, 0, 0},
    {&__pyx_n_s_exception, __pyx_k_exception, sizeof(__pyx_k_exception), 0, 0, 1, 1},
    {&__pyx_n_s_exists, __pyx_k_exists, sizeof(__pyx_k_exists), 0, 0, 1, 1},
    {&__pyx_n_s_exit, __pyx_k_exit, sizeof(__pyx_k_exit), 0, 0, 1, 1},
    {&__pyx_n_s_extend, __pyx_k_extend, sizeof(__pyx_k_extend), 0, 0, 1, 1},
    {&__pyx_n_s_extra_args, __pyx_k_extra_args, sizeof(__pyx_k_extra_args), 0, 0, 1, 1},
    {&__pyx_n_s_fn, __pyx_k_fn, sizeof(__pyx_k_fn), 0, 0, 1, 1},
    {&__pyx_n_s_format, __pyx_k_format, sizeof(__pyx_k_format), 0, 0, 1, 1},
    {&__pyx_n_s_fsencode, __pyx_k_fsencode, sizeof(__pyx_k_fsencode), 0, 0, 1, 1},
    {&__pyx_n_s_get_encoding_error_handler, __pyx_k_get_encoding_error_handler, sizeof(__pyx_k_get_encoding_error_handler), 0, 0, 1, 1},
    {&__pyx_n_u_get_encoding_error_handler, __pyx_k_get_encoding_error_handler, sizeof(__pyx_k_get_encoding_error_handler), 0, 1, 0, 1},
    {&__pyx_n_s_getdefaultencoding, __pyx_k_getdefaultencoding, sizeof(__pyx_k_getdefaultencoding), 0, 0, 1, 1},
    {&__pyx_n_s_getfilesystemencoding, __pyx_k_getfilesystemencoding, sizeof(__pyx_k_getfilesystemencoding), 0, 0, 1, 1},
    {&__pyx_n_s_i, __pyx_k_i, sizeof(__pyx_k_i), 0, 0, 1, 1},
    {&__pyx_n_s_import, __pyx_k_import, sizeof(__pyx_k_import), 0, 0, 1, 1},
    {&__pyx_n_b_index, __pyx_k_index, sizeof(__pyx_k_index), 0, 0, 0, 1},
    {&__pyx_n_u_index, __pyx_k_index, sizeof(__pyx_k_index), 0, 1, 0, 1},
    {&__pyx_n_s_inf, __pyx_k_inf, sizeof(__pyx_k_inf), 0, 0, 1, 1},
    {&__pyx_n_s_initializing, __pyx_k_initializing, sizeof(__pyx_k_initializing), 0, 0, 1, 1},
    {&__pyx_n_s_input_str, __pyx_k_input_str, sizeof(__pyx_k_input_str), 0, 0, 1, 1},
    {&__pyx_kp_u_invalid_coordinates_start_i_stop, __pyx_k_invalid_coordinates_start_i_stop, sizeof(__pyx_k_invalid_coordinates_start_i_stop), 0, 1, 0, 0},
    {&__pyx_n_s_io, __pyx_k_io, sizeof(__pyx_k_io), 0, 0, 1, 1},
    {&__pyx_n_s_is_coroutine, __pyx_k_is_coroutine, sizeof(__pyx_k_is_coroutine), 0, 0, 1, 1},
    {&__pyx_n_s_is_usage, __pyx_k_is_usage, sizeof(__pyx_k_is_usage), 0, 0, 1, 1},
    {&__pyx_n_s_l, __pyx_k_l, sizeof(__pyx_k_l), 0, 0, 1, 1},
    {&__pyx_n_s_latin1_replace, __pyx_k_latin1_replace, sizeof(__pyx_k_latin1_replace), 0, 0, 1, 1},
    {&__pyx_kp_u_m, __pyx_k_m, sizeof(__pyx_k_m), 0, 1, 0, 0},
    {&__pyx_n_s_main, __pyx_k_main, sizeof(__pyx_k_main), 0, 0, 1, 1},
    {&__pyx_n_s_method, __pyx_k_method, sizeof(__pyx_k_method), 0, 0, 1, 1},
    {&__pyx_kp_u_min_shift, __pyx_k_min_shift, sizeof(__pyx_k_min_shift), 0, 1, 0, 0},
    {&__pyx_n_s_mkstemp, __pyx_k_mkstemp, sizeof(__pyx_k_mkstemp), 0, 0, 1, 1},
    {&__pyx_n_u_mpileup, __pyx_k_mpileup, sizeof(__pyx_k_mpileup), 0, 1, 0, 1},
    {&__pyx_n_s_n, __pyx_k_n, sizeof(__pyx_k_n), 0, 0, 1, 1},
    {&__pyx_n_s_name, __pyx_k_name, sizeof(__pyx_k_name), 0, 0, 1, 1},
    {&__pyx_n_s_name_2, __pyx_k_name_2, sizeof(__pyx_k_name_2), 0, 0, 1, 1},
    {&__pyx_kp_u_neither_contig_nor_region_are_gi, __pyx_k_neither_contig_nor_region_are_gi, sizeof(__pyx_k_neither_contig_nor_region_are_gi), 0, 1, 0, 0},
    {&__pyx_kp_u_o, __pyx_k_o, sizeof(__pyx_k_o), 0, 1, 0, 0},
    {&__pyx_kp_u_o_2, __pyx_k_o_2, sizeof(__pyx_k_o_2), 0, 1, 0, 0},
    {&__pyx_n_s_object, __pyx_k_object, sizeof(__pyx_k_object), 0, 0, 1, 1},
    {&__pyx_n_s_offset, __pyx_k_offset, sizeof(__pyx_k_offset), 0, 0, 1, 1},
    {&__pyx_n_s_open, __pyx_k_open, sizeof(__pyx_k_open), 0, 0, 1, 1},
    {&__pyx_n_s_os, __pyx_k_os, sizeof(__pyx_k_os), 0, 0, 1, 1},
    {&__pyx_n_s_out, __pyx_k_out, sizeof(__pyx_k_out), 0, 0, 1, 1},
    {&__pyx_n_s_out_stderr, __pyx_k_out_stderr, sizeof(__pyx_k_out_stderr), 0, 0, 1, 1},
    {&__pyx_n_s_out_stdout, __pyx_k_out_stdout, sizeof(__pyx_k_out_stdout), 0, 0, 1, 1},
    {&__pyx_kp_u_output, __pyx_k_output, sizeof(__pyx_k_output), 0, 1, 0, 0},
    {&__pyx_kp_u_output_file, __pyx_k_output_file, sizeof(__pyx_k_output_file), 0, 1, 0, 0},
    {&__pyx_n_s_parse_region, __pyx_k_parse_region, sizeof(__pyx_k_parse_region), 0, 0, 1, 1},
    {&__pyx_n_s_path, __pyx_k_path, sizeof(__pyx_k_path), 0, 0, 1, 1},
    {&__pyx_n_s_pysam_dispatch, __pyx_k_pysam_dispatch, sizeof(__pyx_k_pysam_dispatch), 0, 0, 1, 1},
    {&__pyx_n_s_pysam_dispatch_locals__collect, __pyx_k_pysam_dispatch_locals__collect, sizeof(__pyx_k_pysam_dispatch_locals__collect), 0, 0, 1, 1},
    {&__pyx_kp_u_pysam_latin1replace, __pyx_k_pysam_latin1replace, sizeof(__pyx_k_pysam_latin1replace), 0, 1, 0, 0},
    {&__pyx_n_s_pysam_libcutils, __pyx_k_pysam_libcutils, sizeof(__pyx_k_pysam_libcutils), 0, 0, 1, 1},
    {&__pyx_kp_s_pysam_libcutils_pyx, __pyx_k_pysam_libcutils_pyx, sizeof(__pyx_k_pysam_libcutils_pyx), 0, 0, 1, 0},
    {&__pyx_n_s_qualities, __pyx_k_qualities, sizeof(__pyx_k_qualities), 0, 0, 1, 1},
    {&__pyx_n_s_qualities_to_qualitystring, __pyx_k_qualities_to_qualitystring, sizeof(__pyx_k_qualities_to_qualitystring), 0, 0, 1, 1},
    {&__pyx_n_u_qualities_to_qualitystring, __pyx_k_qualities_to_qualitystring, sizeof(__pyx_k_qualities_to_qualitystring), 0, 1, 0, 1},
    {&__pyx_n_s_qualitystring_to_array, __pyx_k_qualitystring_to_array, sizeof(__pyx_k_qualitystring_to_array), 0, 0, 1, 1},
    {&__pyx_n_u_qualitystring_to_array, __pyx_k_qualitystring_to_array, sizeof(__pyx_k_qualitystring_to_array), 0, 1, 0, 1},
    {&__pyx_n_u_r, __pyx_k_r, sizeof(__pyx_k_r), 0, 1, 0, 1},
    {&__pyx_n_u_rb, __pyx_k_rb, sizeof(__pyx_k_rb), 0, 1, 0, 1},
    {&__pyx_n_s_re, __pyx_k_re, sizeof(__pyx_k_re), 0, 0, 1, 1},
    {&__pyx_n_s_read, __pyx_k_read, sizeof(__pyx_k_read), 0, 0, 1, 1},
    {&__pyx_n_s_reference, __pyx_k_reference, sizeof(__pyx_k_reference), 0, 0, 1, 1},
    {&__pyx_n_s_region, __pyx_k_region, sizeof(__pyx_k_region), 0, 0, 1, 1},
    {&__pyx_n_s_register_error, __pyx_k_register_error, sizeof(__pyx_k_register_error), 0, 0, 1, 1},
    {&__pyx_n_s_remove, __pyx_k_remove, sizeof(__pyx_k_remove), 0, 0, 1, 1},
    {&__pyx_n_s_retval, __pyx_k_retval, sizeof(__pyx_k_retval), 0, 0, 1, 1},
    {&__pyx_n_u_roh, __pyx_k_roh, sizeof(__pyx_k_roh), 0, 1, 0, 1},
    {&__pyx_n_b_samtools, __pyx_k_samtools, sizeof(__pyx_k_samtools), 0, 0, 0, 1},
    {&__pyx_n_u_samtools, __pyx_k_samtools, sizeof(__pyx_k_samtools), 0, 1, 0, 1},
    {&__pyx_n_s_save_stdout, __pyx_k_save_stdout, sizeof(__pyx_k_save_stdout), 0, 0, 1, 1},
    {&__pyx_n_s_set_encoding_error_handler, __pyx_k_set_encoding_error_handler, sizeof(__pyx_k_set_encoding_error_handler), 0, 0, 1, 1},
    {&__pyx_n_u_set_encoding_error_handler, __pyx_k_set_encoding_error_handler, sizeof(__pyx_k_set_encoding_error_handler), 0, 1, 0, 1},
    {&__pyx_n_s_skip_next, __pyx_k_skip_next, sizeof(__pyx_k_skip_next), 0, 0, 1, 1},
    {&__pyx_n_s_spec, __pyx_k_spec, sizeof(__pyx_k_spec), 0, 0, 1, 1},
    {&__pyx_n_s_split, __pyx_k_split, sizeof(__pyx_k_split), 0, 0, 1, 1},
    {&__pyx_n_s_start, __pyx_k_start, sizeof(__pyx_k_start), 0, 0, 1, 1},
    {&__pyx_kp_u_start_out_of_range_i, __pyx_k_start_out_of_range_i, sizeof(__pyx_k_start_out_of_range_i), 0, 1, 0, 0},
    {&__pyx_n_s_startswith, __pyx_k_startswith, sizeof(__pyx_k_startswith), 0, 0, 1, 1},
    {&__pyx_n_u_stats, __pyx_k_stats, sizeof(__pyx_k_stats), 0, 1, 0, 1},
    {&__pyx_n_s_stderr_f, __pyx_k_stderr_f, sizeof(__pyx_k_stderr_f), 0, 0, 1, 1},
    {&__pyx_n_s_stderr_h, __pyx_k_stderr_h, sizeof(__pyx_k_stderr_h), 0, 0, 1, 1},
    {&__pyx_n_s_stdout_f, __pyx_k_stdout_f, sizeof(__pyx_k_stdout_f), 0, 0, 1, 1},
    {&__pyx_n_s_stdout_h, __pyx_k_stdout_h, sizeof(__pyx_k_stdout_h), 0, 0, 1, 1},
    {&__pyx_n_s_stdout_option, __pyx_k_stdout_option, sizeof(__pyx_k_stdout_option), 0, 0, 1, 1},
    {&__pyx_n_s_stop, __pyx_k_stop, sizeof(__pyx_k_stop), 0, 0, 1, 1},
    {&__pyx_kp_u_stop_and_end_should_not_both_be, __pyx_k_stop_and_end_should_not_both_be, sizeof(__pyx_k_stop_and_end_should_not_both_be), 0, 1, 0, 0},
    {&__pyx_kp_u_stop_out_of_range_i, __pyx_k_stop_out_of_range_i, sizeof(__pyx_k_stop_out_of_range_i), 0, 1, 0, 0},
    {&__pyx_n_u_strict, __pyx_k_strict, sizeof(__pyx_k_strict), 0, 1, 0, 1},
    {&__pyx_n_s_string, __pyx_k_string, sizeof(__pyx_k_string), 0, 0, 1, 1},
    {&__pyx_n_s_sys, __pyx_k_sys, sizeof(__pyx_k_sys), 0, 0, 1, 1},
    {&__pyx_n_s_tempfile, __pyx_k_tempfile, sizeof(__pyx_k_tempfile), 0, 0, 1, 1},
    {&__pyx_n_s_test, __pyx_k_test, sizeof(__pyx_k_test), 0, 0, 1, 1},
    {&__pyx_kp_u_threads, __pyx_k_threads, sizeof(__pyx_k_threads), 0, 1, 0, 0},
    {&__pyx_n_s_tobytes, __pyx_k_tobytes, sizeof(__pyx_k_tobytes), 0, 0, 1, 1},
    {&__pyx_n_s_types, __pyx_k_types, sizeof(__pyx_k_types), 0, 0, 1, 1},
    {&__pyx_kp_u_utf_8, __pyx_k_utf_8, sizeof(__pyx_k_utf_8), 0, 1, 0, 0},
    {&__pyx_n_u_view, __pyx_k_view, sizeof(__pyx_k_view), 0, 1, 0, 1},
    {0, 0, 0, 0, 0, 0, 0}
  };
  return __Pyx_InitStrings(__pyx_string_tab);
}
/* #### Code section: cached_builtins ### */
static CYTHON_SMALL_CODE int __Pyx_InitCachedBuiltins(void) {
  __pyx_builtin_chr = __Pyx_GetBuiltinName(__pyx_n_s_chr); if (!__pyx_builtin_chr) __PYX_ERR(0, 81, __pyx_L1_error)
  __pyx_builtin_TypeError = __Pyx_GetBuiltinName(__pyx_n_s_TypeError); if (!__pyx_builtin_TypeError) __PYX_ERR(0, 135, __pyx_L1_error)
  __pyx_builtin_ValueError = __Pyx_GetBuiltinName(__pyx_n_s_ValueError); if (!__pyx_builtin_ValueError) __PYX_ERR(0, 217, __pyx_L1_error)
  __pyx_builtin_OverflowError = __Pyx_GetBuiltinName(__pyx_n_s_OverflowError); if (!__pyx_builtin_OverflowError) __PYX_ERR(0, 236, __pyx_L1_error)
  __pyx_builtin_IOError = __Pyx_GetBuiltinName(__pyx_n_s_IOError); if (!__pyx_builtin_IOError) __PYX_ERR(0, 308, __pyx_L1_error)
  __pyx_builtin_open = __Pyx_GetBuiltinName(__pyx_n_s_open); if (!__pyx_builtin_open) __PYX_ERR(0, 415, __pyx_L1_error)
  __pyx_builtin_UnicodeDecodeError = __Pyx_GetBuiltinName(__pyx_n_s_UnicodeDecodeError); if (!__pyx_builtin_UnicodeDecodeError) __PYX_ERR(0, 417, __pyx_L1_error)
  __pyx_builtin_MemoryError = __Pyx_GetBuiltinName(__pyx_n_s_MemoryError); if (!__pyx_builtin_MemoryError) __PYX_ERR(2, 120, __pyx_L1_error)
  return 0;
  __pyx_L1_error:;
  return -1;
}
/* #### Code section: cached_constants ### */

static CYTHON_SMALL_CODE int __Pyx_InitCachedConstants(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_InitCachedConstants", 0);

  /* "pysam/libcutils.pyx":135
 *         return s.encode(encoding or TEXT_ENCODING, errors or ERROR_HANDLER)
 *     else:
 *         raise TypeError("Argument must be string, bytes or unicode.")             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __pyx_tuple__2 = PyTuple_Pack(1, __pyx_kp_u_Argument_must_be_string_bytes_or); if (unlikely(!__pyx_tuple__2)) __PYX_ERR(0, 135, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__2);
  __Pyx_GIVEREF(__pyx_tuple__2);

  /* "pysam/libcutils.pyx":217
 *     if reference is not None:
 *         if contig is not None:
 *            raise ValueError('contig and reference should not both be specified')             # <<<<<<<<<<<<<<
 *         contig = reference
 * 
 */
  __pyx_tuple__3 = PyTuple_Pack(1, __pyx_kp_u_contig_and_reference_should_not); if (unlikely(!__pyx_tuple__3)) __PYX_ERR(0, 217, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__3);
  __Pyx_GIVEREF(__pyx_tuple__3);

  /* "pysam/libcutils.pyx":221
 * 
 *     if contig is not None and region is not None:
 *         raise ValueError('contig/reference and region should not both be specified')             # <<<<<<<<<<<<<<
 * 
 *     if end is not None:
 */
  __pyx_tuple__4 = PyTuple_Pack(1, __pyx_kp_u_contig_reference_and_region_shou); if (unlikely(!__pyx_tuple__4)) __PYX_ERR(0, 221, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__4);
  __Pyx_GIVEREF(__pyx_tuple__4);

  /* "pysam/libcutils.pyx":225
 *     if end is not None:
 *         if stop is not None:
 *             raise ValueError('stop and end should not both be specified')             # <<<<<<<<<<<<<<
 *         stop = end
 * 
 */
  __pyx_tuple__5 = PyTuple_Pack(1, __pyx_kp_u_stop_and_end_should_not_both_be); if (unlikely(!__pyx_tuple__5)) __PYX_ERR(0, 225, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__5);
  __Pyx_GIVEREF(__pyx_tuple__5);

  /* "pysam/libcutils.pyx":229
 * 
 *     if contig is None and region is None:
 *         raise ValueError("neither contig nor region are given")             # <<<<<<<<<<<<<<
 * 
 *     rstart = 0
 */
  __pyx_tuple__6 = PyTuple_Pack(1, __pyx_kp_u_neither_contig_nor_region_are_gi); if (unlikely(!__pyx_tuple__6)) __PYX_ERR(0, 229, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__6);
  __Pyx_GIVEREF(__pyx_tuple__6);

  /* "pysam/libcutils.pyx":415
 *         out = []
 *         try:
 *             with open(fn, "r") as inf:             # <<<<<<<<<<<<<<
 *                 out = inf.read()
 *         except UnicodeDecodeError:
 */
  __pyx_tuple__9 = PyTuple_Pack(3, Py_None, Py_None, Py_None); if (unlikely(!__pyx_tuple__9)) __PYX_ERR(0, 415, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__9);
  __Pyx_GIVEREF(__pyx_tuple__9);

  /* "pysam/libcutils.pyx":412
 * 
 *     # get error messages
 *     def _collect(fn):             # <<<<<<<<<<<<<<
 *         out = []
 *         try:
 */
  __pyx_tuple__12 = PyTuple_Pack(3, __pyx_n_s_fn, __pyx_n_s_out, __pyx_n_s_inf); if (unlikely(!__pyx_tuple__12)) __PYX_ERR(0, 412, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__12);
  __Pyx_GIVEREF(__pyx_tuple__12);
  __pyx_codeobj__13 = (PyObject*)__Pyx_PyCode_New(1, 0, 0, 3, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__12, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_collect, 412, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__13)) __PYX_ERR(0, 412, __pyx_L1_error)

  /* "pysam/libcutils.pyx":35
 * #################################################################
 * # Utility functions for quality string conversions
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:
 */
  __pyx_tuple__16 = PyTuple_Pack(2, __pyx_n_s_input_str, __pyx_n_s_offset); if (unlikely(!__pyx_tuple__16)) __PYX_ERR(0, 35, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__16);
  __Pyx_GIVEREF(__pyx_tuple__16);
  __pyx_codeobj__17 = (PyObject*)__Pyx_PyCode_New(2, 0, 0, 2, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__16, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_qualitystring_to_array, 35, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__17)) __PYX_ERR(0, 35, __pyx_L1_error)
  __pyx_tuple__18 = PyTuple_Pack(1, __pyx_int_33); if (unlikely(!__pyx_tuple__18)) __PYX_ERR(0, 35, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__18);
  __Pyx_GIVEREF(__pyx_tuple__18);

  /* "pysam/libcutils.pyx":44
 * 
 * 
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert an array of quality values to a string."""
 *     if qualities is None:
 */
  __pyx_tuple__19 = PyTuple_Pack(2, __pyx_n_s_qualities, __pyx_n_s_offset); if (unlikely(!__pyx_tuple__19)) __PYX_ERR(0, 44, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__19);
  __Pyx_GIVEREF(__pyx_tuple__19);
  __pyx_codeobj__20 = (PyObject*)__Pyx_PyCode_New(2, 0, 0, 2, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__19, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_array_to_qualitystring, 44, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__20)) __PYX_ERR(0, 44, __pyx_L1_error)

  /* "pysam/libcutils.pyx":58
 * 
 * 
 * cpdef qualities_to_qualitystring(qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a list or array of quality scores to the string
 *     representation used in the SAM format.
 */
  __pyx_codeobj__21 = (PyObject*)__Pyx_PyCode_New(2, 0, 0, 2, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__19, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_qualities_to_qualitystring, 58, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__21)) __PYX_ERR(0, 58, __pyx_L1_error)

  /* "pysam/libcutils.pyx":89
 * 
 * # Codec error handler that just interprets each bad byte as ISO-8859-1.
 * def latin1_replace(exception):             # <<<<<<<<<<<<<<
 *     return (chr(exception.object[exception.start]), exception.end)
 * 
 */
  __pyx_tuple__22 = PyTuple_Pack(1, __pyx_n_s_exception); if (unlikely(!__pyx_tuple__22)) __PYX_ERR(0, 89, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__22);
  __Pyx_GIVEREF(__pyx_tuple__22);
  __pyx_codeobj__23 = (PyObject*)__Pyx_PyCode_New(1, 0, 0, 1, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__22, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_latin1_replace, 89, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__23)) __PYX_ERR(0, 89, __pyx_L1_error)

  /* "pysam/libcutils.pyx":97
 * cdef str ERROR_HANDLER = 'strict'
 * 
 * cpdef get_encoding_error_handler():             # <<<<<<<<<<<<<<
 *     return ERROR_HANDLER
 * 
 */
  __pyx_codeobj__24 = (PyObject*)__Pyx_PyCode_New(0, 0, 0, 0, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_get_encoding_error_handler, 97, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__24)) __PYX_ERR(0, 97, __pyx_L1_error)

  /* "pysam/libcutils.pyx":100
 *     return ERROR_HANDLER
 * 
 * cpdef set_encoding_error_handler(name):             # <<<<<<<<<<<<<<
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER
 */
  __pyx_tuple__25 = PyTuple_Pack(1, __pyx_n_s_name); if (unlikely(!__pyx_tuple__25)) __PYX_ERR(0, 100, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__25);
  __Pyx_GIVEREF(__pyx_tuple__25);
  __pyx_codeobj__26 = (PyObject*)__Pyx_PyCode_New(1, 0, 0, 1, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__25, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_set_encoding_error_handler, 100, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__26)) __PYX_ERR(0, 100, __pyx_L1_error)

  /* "pysam/libcutils.pyx":177
 * 
 * 
 * cpdef parse_region(contig=None,             # <<<<<<<<<<<<<<
 *                    start=None,
 *                    stop=None,
 */
  __pyx_tuple__27 = PyTuple_Pack(6, __pyx_n_s_contig, __pyx_n_s_start, __pyx_n_s_stop, __pyx_n_s_region, __pyx_n_s_reference, __pyx_n_s_end); if (unlikely(!__pyx_tuple__27)) __PYX_ERR(0, 177, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__27);
  __Pyx_GIVEREF(__pyx_tuple__27);
  __pyx_codeobj__28 = (PyObject*)__Pyx_PyCode_New(6, 0, 0, 6, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__27, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_parse_region, 177, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__28)) __PYX_ERR(0, 177, __pyx_L1_error)
  __pyx_tuple__29 = PyTuple_Pack(6, Py_None, Py_None, Py_None, Py_None, Py_None, Py_None); if (unlikely(!__pyx_tuple__29)) __PYX_ERR(0, 177, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__29);
  __Pyx_GIVEREF(__pyx_tuple__29);

  /* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */
  __pyx_tuple__30 = PyTuple_Pack(26, __pyx_n_s_collection, __pyx_n_s_method, __pyx_n_s_args, __pyx_n_s_catch_stdout, __pyx_n_s_is_usage, __pyx_n_s_save_stdout, __pyx_n_s_ARGUMENTS, __pyx_n_s_skip_next, __pyx_n_s_arg, __pyx_n_s_stderr_h, __pyx_n_s_stderr_f, __pyx_n_s_stdout_f, __pyx_n_s_stdout_h, __pyx_n_s_MAP_STDOUT_OPTIONS, __pyx_n_s_stdout_option, __pyx_n_s_cargs, __pyx_n_s_i, __pyx_n_s_n, __pyx_n_s_retval, __pyx_n_s_l, __pyx_n_s_extra_args, __pyx_n_s_collect, __pyx_n_s_collect, __pyx_n_s_out_stderr, __pyx_n_s_out_stdout, __pyx_n_s_a); if (unlikely(!__pyx_tuple__30)) __PYX_ERR(0, 275, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__30);
  __Pyx_GIVEREF(__pyx_tuple__30);
  __pyx_codeobj__31 = (PyObject*)__Pyx_PyCode_New(6, 0, 0, 26, 0, CO_OPTIMIZED|CO_NEWLOCALS, __pyx_empty_bytes, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_tuple__30, __pyx_empty_tuple, __pyx_empty_tuple, __pyx_kp_s_pysam_libcutils_pyx, __pyx_n_s_pysam_dispatch, 275, __pyx_empty_bytes); if (unlikely(!__pyx_codeobj__31)) __PYX_ERR(0, 275, __pyx_L1_error)
  __pyx_tuple__32 = PyTuple_Pack(4, Py_None, ((PyObject *)Py_True), ((PyObject *)Py_False), Py_None); if (unlikely(!__pyx_tuple__32)) __PYX_ERR(0, 275, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_tuple__32);
  __Pyx_GIVEREF(__pyx_tuple__32);
  __Pyx_RefNannyFinishContext();
  return 0;
  __pyx_L1_error:;
  __Pyx_RefNannyFinishContext();
  return -1;
}
/* #### Code section: init_constants ### */

static CYTHON_SMALL_CODE int __Pyx_InitConstants(void) {
  if (__Pyx_CreateStringTabAndInitStrings() < 0) __PYX_ERR(0, 1, __pyx_L1_error);
  __pyx_int_1 = PyInt_FromLong(1); if (unlikely(!__pyx_int_1)) __PYX_ERR(0, 1, __pyx_L1_error)
  __pyx_int_33 = PyInt_FromLong(33); if (unlikely(!__pyx_int_33)) __PYX_ERR(0, 1, __pyx_L1_error)
  __pyx_int_neg_1 = PyInt_FromLong(-1); if (unlikely(!__pyx_int_neg_1)) __PYX_ERR(0, 1, __pyx_L1_error)
  return 0;
  __pyx_L1_error:;
  return -1;
}
/* #### Code section: init_globals ### */

static CYTHON_SMALL_CODE int __Pyx_InitGlobals(void) {
  return 0;
}
/* #### Code section: init_module ### */

static CYTHON_SMALL_CODE int __Pyx_modinit_global_init_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_variable_export_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_function_export_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_type_init_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_type_import_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_variable_import_code(void); /*proto*/
static CYTHON_SMALL_CODE int __Pyx_modinit_function_import_code(void); /*proto*/

static int __Pyx_modinit_global_init_code(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_modinit_global_init_code", 0);
  /*--- Global init code ---*/
  __pyx_v_5pysam_9libcutils_ERROR_HANDLER = ((PyObject*)Py_None); Py_INCREF(Py_None);
  __pyx_v_5pysam_9libcutils_FILENAME_ENCODING = ((PyObject*)Py_None); Py_INCREF(Py_None);
  __pyx_v_5pysam_9libcutils_TEXT_ENCODING = ((PyObject*)Py_None); Py_INCREF(Py_None);
  __Pyx_RefNannyFinishContext();
  return 0;
}

static int __Pyx_modinit_variable_export_code(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_modinit_variable_export_code", 0);
  /*--- Variable export code ---*/
  __Pyx_RefNannyFinishContext();
  return 0;
}

static int __Pyx_modinit_function_export_code(void) {
  __Pyx_RefNannyDeclarations
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("__Pyx_modinit_function_export_code", 0);
  /*--- Function export code ---*/
  if (__Pyx_ExportFunction("parse_region", (void (*)(void))__pyx_f_5pysam_9libcutils_parse_region, "PyObject *(int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_parse_region *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("libc_whence_from_io", (void (*)(void))__pyx_f_5pysam_9libcutils_libc_whence_from_io, "int (int)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("qualitystring_to_array", (void (*)(void))__pyx_f_5pysam_9libcutils_qualitystring_to_array, "arrayobject *(PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualitystring_to_array *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("array_to_qualitystring", (void (*)(void))__pyx_f_5pysam_9libcutils_array_to_qualitystring, "PyObject *(arrayobject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_array_to_qualitystring *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("qualities_to_qualitystring", (void (*)(void))__pyx_f_5pysam_9libcutils_qualities_to_qualitystring, "PyObject *(PyObject *, int __pyx_skip_dispatch, struct __pyx_opt_args_5pysam_9libcutils_qualities_to_qualitystring *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("get_encoding_error_handler", (void (*)(void))__pyx_f_5pysam_9libcutils_get_encoding_error_handler, "PyObject *(int __pyx_skip_dispatch)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("set_encoding_error_handler", (void (*)(void))__pyx_f_5pysam_9libcutils_set_encoding_error_handler, "PyObject *(PyObject *, int __pyx_skip_dispatch)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("charptr_to_str", (void (*)(void))__pyx_f_5pysam_9libcutils_charptr_to_str, "PyObject *(char const *, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("charptr_to_bytes", (void (*)(void))__pyx_f_5pysam_9libcutils_charptr_to_bytes, "PyObject *(char const *, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_bytes *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("charptr_to_str_w_len", (void (*)(void))__pyx_f_5pysam_9libcutils_charptr_to_str_w_len, "PyObject *(char const *, size_t, struct __pyx_opt_args_5pysam_9libcutils_charptr_to_str_w_len *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("force_str", (void (*)(void))__pyx_f_5pysam_9libcutils_force_str, "PyObject *(PyObject *, struct __pyx_opt_args_5pysam_9libcutils_force_str *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("force_bytes", (void (*)(void))__pyx_f_5pysam_9libcutils_force_bytes, "PyObject *(PyObject *, struct __pyx_opt_args_5pysam_9libcutils_force_bytes *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("decode_bytes", (void (*)(void))__pyx_f_5pysam_9libcutils_decode_bytes, "PyObject *(PyObject *, struct __pyx_opt_args_5pysam_9libcutils_decode_bytes *__pyx_optional_args)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("encode_filename", (void (*)(void))__pyx_f_5pysam_9libcutils_encode_filename, "PyObject *(PyObject *)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  if (__Pyx_ExportFunction("from_string_and_size", (void (*)(void))__pyx_f_5pysam_9libcutils_from_string_and_size, "PyObject *(char const *, size_t)") < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  __Pyx_RefNannyFinishContext();
  return 0;
  __pyx_L1_error:;
  __Pyx_RefNannyFinishContext();
  return -1;
}

static int __Pyx_modinit_type_init_code(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_modinit_type_init_code", 0);
  /*--- Type init code ---*/
  __Pyx_RefNannyFinishContext();
  return 0;
}

static int __Pyx_modinit_type_import_code(void) {
  __Pyx_RefNannyDeclarations
  PyObject *__pyx_t_1 = NULL;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannySetupContext("__Pyx_modinit_type_import_code", 0);
  /*--- Type import code ---*/
  __pyx_t_1 = PyImport_ImportModule(__Pyx_BUILTIN_MODULE_NAME); if (unlikely(!__pyx_t_1)) __PYX_ERR(3, 9, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_ptype_7cpython_4type_type = __Pyx_ImportType_3_0_2(__pyx_t_1, __Pyx_BUILTIN_MODULE_NAME, "type", 
  #if defined(PYPY_VERSION_NUM) && PYPY_VERSION_NUM < 0x050B0000
  sizeof(PyTypeObject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(PyTypeObject),
  #elif CYTHON_COMPILING_IN_LIMITED_API
  sizeof(PyTypeObject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(PyTypeObject),
  #else
  sizeof(PyHeapTypeObject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(PyHeapTypeObject),
  #endif
  __Pyx_ImportType_CheckSize_Warn_3_0_2); if (!__pyx_ptype_7cpython_4type_type) __PYX_ERR(3, 9, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __pyx_t_1 = PyImport_ImportModule(__Pyx_BUILTIN_MODULE_NAME); if (unlikely(!__pyx_t_1)) __PYX_ERR(4, 8, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_ptype_7cpython_4bool_bool = __Pyx_ImportType_3_0_2(__pyx_t_1, __Pyx_BUILTIN_MODULE_NAME, "bool", sizeof(PyBoolObject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(PyBoolObject),__Pyx_ImportType_CheckSize_Warn_3_0_2); if (!__pyx_ptype_7cpython_4bool_bool) __PYX_ERR(4, 8, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __pyx_t_1 = PyImport_ImportModule(__Pyx_BUILTIN_MODULE_NAME); if (unlikely(!__pyx_t_1)) __PYX_ERR(5, 15, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_ptype_7cpython_7complex_complex = __Pyx_ImportType_3_0_2(__pyx_t_1, __Pyx_BUILTIN_MODULE_NAME, "complex", sizeof(PyComplexObject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(PyComplexObject),__Pyx_ImportType_CheckSize_Warn_3_0_2); if (!__pyx_ptype_7cpython_7complex_complex) __PYX_ERR(5, 15, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __pyx_t_1 = PyImport_ImportModule("array"); if (unlikely(!__pyx_t_1)) __PYX_ERR(2, 69, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_1);
  __pyx_ptype_7cpython_5array_array = __Pyx_ImportType_3_0_2(__pyx_t_1, "array", "array", sizeof(arrayobject), __PYX_GET_STRUCT_ALIGNMENT_3_0_2(arrayobject),__Pyx_ImportType_CheckSize_Warn_3_0_2); if (!__pyx_ptype_7cpython_5array_array) __PYX_ERR(2, 69, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_1); __pyx_t_1 = 0;
  __Pyx_RefNannyFinishContext();
  return 0;
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_1);
  __Pyx_RefNannyFinishContext();
  return -1;
}

static int __Pyx_modinit_variable_import_code(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_modinit_variable_import_code", 0);
  /*--- Variable import code ---*/
  __Pyx_RefNannyFinishContext();
  return 0;
}

static int __Pyx_modinit_function_import_code(void) {
  __Pyx_RefNannyDeclarations
  __Pyx_RefNannySetupContext("__Pyx_modinit_function_import_code", 0);
  /*--- Function import code ---*/
  __Pyx_RefNannyFinishContext();
  return 0;
}


#if PY_MAJOR_VERSION >= 3
#if CYTHON_PEP489_MULTI_PHASE_INIT
static PyObject* __pyx_pymod_create(PyObject *spec, PyModuleDef *def); /*proto*/
static int __pyx_pymod_exec_libcutils(PyObject* module); /*proto*/
static PyModuleDef_Slot __pyx_moduledef_slots[] = {
  {Py_mod_create, (void*)__pyx_pymod_create},
  {Py_mod_exec, (void*)__pyx_pymod_exec_libcutils},
  {0, NULL}
};
#endif

#ifdef __cplusplus
namespace {
  struct PyModuleDef __pyx_moduledef =
  #else
  static struct PyModuleDef __pyx_moduledef =
  #endif
  {
      PyModuleDef_HEAD_INIT,
      "libcutils",
      0, /* m_doc */
    #if CYTHON_PEP489_MULTI_PHASE_INIT
      0, /* m_size */
    #elif CYTHON_USE_MODULE_STATE
      sizeof(__pyx_mstate), /* m_size */
    #else
      -1, /* m_size */
    #endif
      __pyx_methods /* m_methods */,
    #if CYTHON_PEP489_MULTI_PHASE_INIT
      __pyx_moduledef_slots, /* m_slots */
    #else
      NULL, /* m_reload */
    #endif
    #if CYTHON_USE_MODULE_STATE
      __pyx_m_traverse, /* m_traverse */
      __pyx_m_clear, /* m_clear */
      NULL /* m_free */
    #else
      NULL, /* m_traverse */
      NULL, /* m_clear */
      NULL /* m_free */
    #endif
  };
  #ifdef __cplusplus
} /* anonymous namespace */
#endif
#endif

#ifndef CYTHON_NO_PYINIT_EXPORT
#define __Pyx_PyMODINIT_FUNC PyMODINIT_FUNC
#elif PY_MAJOR_VERSION < 3
#ifdef __cplusplus
#define __Pyx_PyMODINIT_FUNC extern "C" void
#else
#define __Pyx_PyMODINIT_FUNC void
#endif
#else
#ifdef __cplusplus
#define __Pyx_PyMODINIT_FUNC extern "C" PyObject *
#else
#define __Pyx_PyMODINIT_FUNC PyObject *
#endif
#endif


#if PY_MAJOR_VERSION < 3
__Pyx_PyMODINIT_FUNC initlibcutils(void) CYTHON_SMALL_CODE; /*proto*/
__Pyx_PyMODINIT_FUNC initlibcutils(void)
#else
__Pyx_PyMODINIT_FUNC PyInit_libcutils(void) CYTHON_SMALL_CODE; /*proto*/
__Pyx_PyMODINIT_FUNC PyInit_libcutils(void)
#if CYTHON_PEP489_MULTI_PHASE_INIT
{
  return PyModuleDef_Init(&__pyx_moduledef);
}
static CYTHON_SMALL_CODE int __Pyx_check_single_interpreter(void) {
    #if PY_VERSION_HEX >= 0x030700A1
    static PY_INT64_T main_interpreter_id = -1;
    PY_INT64_T current_id = PyInterpreterState_GetID(PyThreadState_Get()->interp);
    if (main_interpreter_id == -1) {
        main_interpreter_id = current_id;
        return (unlikely(current_id == -1)) ? -1 : 0;
    } else if (unlikely(main_interpreter_id != current_id))
    #else
    static PyInterpreterState *main_interpreter = NULL;
    PyInterpreterState *current_interpreter = PyThreadState_Get()->interp;
    if (!main_interpreter) {
        main_interpreter = current_interpreter;
    } else if (unlikely(main_interpreter != current_interpreter))
    #endif
    {
        PyErr_SetString(
            PyExc_ImportError,
            "Interpreter change detected - this module can only be loaded into one interpreter per process.");
        return -1;
    }
    return 0;
}
#if CYTHON_COMPILING_IN_LIMITED_API
static CYTHON_SMALL_CODE int __Pyx_copy_spec_to_module(PyObject *spec, PyObject *module, const char* from_name, const char* to_name, int allow_none)
#else
static CYTHON_SMALL_CODE int __Pyx_copy_spec_to_module(PyObject *spec, PyObject *moddict, const char* from_name, const char* to_name, int allow_none)
#endif
{
    PyObject *value = PyObject_GetAttrString(spec, from_name);
    int result = 0;
    if (likely(value)) {
        if (allow_none || value != Py_None) {
#if CYTHON_COMPILING_IN_LIMITED_API
            result = PyModule_AddObject(module, to_name, value);
#else
            result = PyDict_SetItemString(moddict, to_name, value);
#endif
        }
        Py_DECREF(value);
    } else if (PyErr_ExceptionMatches(PyExc_AttributeError)) {
        PyErr_Clear();
    } else {
        result = -1;
    }
    return result;
}
static CYTHON_SMALL_CODE PyObject* __pyx_pymod_create(PyObject *spec, PyModuleDef *def) {
    PyObject *module = NULL, *moddict, *modname;
    CYTHON_UNUSED_VAR(def);
    if (__Pyx_check_single_interpreter())
        return NULL;
    if (__pyx_m)
        return __Pyx_NewRef(__pyx_m);
    modname = PyObject_GetAttrString(spec, "name");
    if (unlikely(!modname)) goto bad;
    module = PyModule_NewObject(modname);
    Py_DECREF(modname);
    if (unlikely(!module)) goto bad;
#if CYTHON_COMPILING_IN_LIMITED_API
    moddict = module;
#else
    moddict = PyModule_GetDict(module);
    if (unlikely(!moddict)) goto bad;
#endif
    if (unlikely(__Pyx_copy_spec_to_module(spec, moddict, "loader", "__loader__", 1) < 0)) goto bad;
    if (unlikely(__Pyx_copy_spec_to_module(spec, moddict, "origin", "__file__", 1) < 0)) goto bad;
    if (unlikely(__Pyx_copy_spec_to_module(spec, moddict, "parent", "__package__", 1) < 0)) goto bad;
    if (unlikely(__Pyx_copy_spec_to_module(spec, moddict, "submodule_search_locations", "__path__", 0) < 0)) goto bad;
    return module;
bad:
    Py_XDECREF(module);
    return NULL;
}


static CYTHON_SMALL_CODE int __pyx_pymod_exec_libcutils(PyObject *__pyx_pyinit_module)
#endif
#endif
{
  int stringtab_initialized = 0;
  #if CYTHON_USE_MODULE_STATE
  int pystate_addmodule_run = 0;
  #endif
  PyObject *__pyx_t_1 = NULL;
  PyObject *__pyx_t_2 = NULL;
  PyObject *__pyx_t_3 = NULL;
  PyObject *__pyx_t_4 = NULL;
  int __pyx_t_5;
  int __pyx_lineno = 0;
  const char *__pyx_filename = NULL;
  int __pyx_clineno = 0;
  __Pyx_RefNannyDeclarations
  #if CYTHON_PEP489_MULTI_PHASE_INIT
  if (__pyx_m) {
    if (__pyx_m == __pyx_pyinit_module) return 0;
    PyErr_SetString(PyExc_RuntimeError, "Module 'libcutils' has already been imported. Re-initialisation is not supported.");
    return -1;
  }
  #elif PY_MAJOR_VERSION >= 3
  if (__pyx_m) return __Pyx_NewRef(__pyx_m);
  #endif
  /*--- Module creation code ---*/
  #if CYTHON_PEP489_MULTI_PHASE_INIT
  __pyx_m = __pyx_pyinit_module;
  Py_INCREF(__pyx_m);
  #else
  #if PY_MAJOR_VERSION < 3
  __pyx_m = Py_InitModule4("libcutils", __pyx_methods, 0, 0, PYTHON_API_VERSION); Py_XINCREF(__pyx_m);
  if (unlikely(!__pyx_m)) __PYX_ERR(0, 1, __pyx_L1_error)
  #elif CYTHON_USE_MODULE_STATE
  __pyx_t_1 = PyModule_Create(&__pyx_moduledef); if (unlikely(!__pyx_t_1)) __PYX_ERR(0, 1, __pyx_L1_error)
  {
    int add_module_result = PyState_AddModule(__pyx_t_1, &__pyx_moduledef);
    __pyx_t_1 = 0; /* transfer ownership from __pyx_t_1 to libcutils pseudovariable */
    if (unlikely((add_module_result < 0))) __PYX_ERR(0, 1, __pyx_L1_error)
    pystate_addmodule_run = 1;
  }
  #else
  __pyx_m = PyModule_Create(&__pyx_moduledef);
  if (unlikely(!__pyx_m)) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #endif
  CYTHON_UNUSED_VAR(__pyx_t_1);
  __pyx_d = PyModule_GetDict(__pyx_m); if (unlikely(!__pyx_d)) __PYX_ERR(0, 1, __pyx_L1_error)
  Py_INCREF(__pyx_d);
  __pyx_b = PyImport_AddModule(__Pyx_BUILTIN_MODULE_NAME); if (unlikely(!__pyx_b)) __PYX_ERR(0, 1, __pyx_L1_error)
  Py_INCREF(__pyx_b);
  __pyx_cython_runtime = PyImport_AddModule((char *) "cython_runtime"); if (unlikely(!__pyx_cython_runtime)) __PYX_ERR(0, 1, __pyx_L1_error)
  Py_INCREF(__pyx_cython_runtime);
  if (PyObject_SetAttrString(__pyx_m, "__builtins__", __pyx_b) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #if CYTHON_REFNANNY
__Pyx_RefNanny = __Pyx_RefNannyImportAPI("refnanny");
if (!__Pyx_RefNanny) {
  PyErr_Clear();
  __Pyx_RefNanny = __Pyx_RefNannyImportAPI("Cython.Runtime.refnanny");
  if (!__Pyx_RefNanny)
      Py_FatalError("failed to import 'refnanny' module");
}
#endif
  __Pyx_RefNannySetupContext("__Pyx_PyMODINIT_FUNC PyInit_libcutils(void)", 0);
  if (__Pyx_check_binary_version() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #ifdef __Pxy_PyFrame_Initialize_Offsets
  __Pxy_PyFrame_Initialize_Offsets();
  #endif
  __pyx_empty_tuple = PyTuple_New(0); if (unlikely(!__pyx_empty_tuple)) __PYX_ERR(0, 1, __pyx_L1_error)
  __pyx_empty_bytes = PyBytes_FromStringAndSize("", 0); if (unlikely(!__pyx_empty_bytes)) __PYX_ERR(0, 1, __pyx_L1_error)
  __pyx_empty_unicode = PyUnicode_FromStringAndSize("", 0); if (unlikely(!__pyx_empty_unicode)) __PYX_ERR(0, 1, __pyx_L1_error)
  #ifdef __Pyx_CyFunction_USED
  if (__pyx_CyFunction_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #ifdef __Pyx_FusedFunction_USED
  if (__pyx_FusedFunction_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #ifdef __Pyx_Coroutine_USED
  if (__pyx_Coroutine_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #ifdef __Pyx_Generator_USED
  if (__pyx_Generator_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #ifdef __Pyx_AsyncGen_USED
  if (__pyx_AsyncGen_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  #ifdef __Pyx_StopAsyncIteration_USED
  if (__pyx_StopAsyncIteration_init(__pyx_m) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  /*--- Library function declarations ---*/
  /*--- Threads initialization code ---*/
  #if defined(WITH_THREAD) && PY_VERSION_HEX < 0x030700F0 && defined(__PYX_FORCE_INIT_THREADS) && __PYX_FORCE_INIT_THREADS
  PyEval_InitThreads();
  #endif
  /*--- Initialize various global constants etc. ---*/
  if (__Pyx_InitConstants() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  stringtab_initialized = 1;
  if (__Pyx_InitGlobals() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #if PY_MAJOR_VERSION < 3 && (__PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT)
  if (__Pyx_init_sys_getdefaultencoding_params() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif
  if (__pyx_module_is_main_pysam__libcutils) {
    if (PyObject_SetAttr(__pyx_m, __pyx_n_s_name_2, __pyx_n_s_main) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  }
  #if PY_MAJOR_VERSION >= 3
  {
    PyObject *modules = PyImport_GetModuleDict(); if (unlikely(!modules)) __PYX_ERR(0, 1, __pyx_L1_error)
    if (!PyDict_GetItemString(modules, "pysam.libcutils")) {
      if (unlikely((PyDict_SetItemString(modules, "pysam.libcutils", __pyx_m) < 0))) __PYX_ERR(0, 1, __pyx_L1_error)
    }
  }
  #endif
  /*--- Builtin init code ---*/
  if (__Pyx_InitCachedBuiltins() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  /*--- Constants init code ---*/
  if (__Pyx_InitCachedConstants() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  /*--- Global type/function init code ---*/
  (void)__Pyx_modinit_global_init_code();
  (void)__Pyx_modinit_variable_export_code();
  if (unlikely((__Pyx_modinit_function_export_code() < 0))) __PYX_ERR(0, 1, __pyx_L1_error)
  (void)__Pyx_modinit_type_init_code();
  if (unlikely((__Pyx_modinit_type_import_code() < 0))) __PYX_ERR(0, 1, __pyx_L1_error)
  (void)__Pyx_modinit_variable_import_code();
  (void)__Pyx_modinit_function_import_code();
  /*--- Execution code ---*/
  #if defined(__Pyx_Generator_USED) || defined(__Pyx_Coroutine_USED)
  if (__Pyx_patch_abc() < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  #endif

  /* "pysam/libcutils.pyx":2
 * # cython: language_level=3
 * import types             # <<<<<<<<<<<<<<
 * import sys
 * import string
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_types, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 2, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_types, __pyx_t_2) < 0) __PYX_ERR(0, 2, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":3
 * # cython: language_level=3
 * import types
 * import sys             # <<<<<<<<<<<<<<
 * import string
 * import re
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_sys, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 3, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_sys, __pyx_t_2) < 0) __PYX_ERR(0, 3, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":4
 * import types
 * import sys
 * import string             # <<<<<<<<<<<<<<
 * import re
 * import tempfile
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_string, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 4, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_string, __pyx_t_2) < 0) __PYX_ERR(0, 4, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":5
 * import sys
 * import string
 * import re             # <<<<<<<<<<<<<<
 * import tempfile
 * import os
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_re, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 5, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_re, __pyx_t_2) < 0) __PYX_ERR(0, 5, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":6
 * import string
 * import re
 * import tempfile             # <<<<<<<<<<<<<<
 * import os
 * import io
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_tempfile, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 6, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_tempfile, __pyx_t_2) < 0) __PYX_ERR(0, 6, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":7
 * import re
 * import tempfile
 * import os             # <<<<<<<<<<<<<<
 * import io
 * from contextlib import contextmanager
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_os, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 7, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_os, __pyx_t_2) < 0) __PYX_ERR(0, 7, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":8
 * import tempfile
 * import os
 * import io             # <<<<<<<<<<<<<<
 * from contextlib import contextmanager
 * from codecs import register_error
 */
  __pyx_t_2 = __Pyx_ImportDottedModule(__pyx_n_s_io, NULL); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 8, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_io, __pyx_t_2) < 0) __PYX_ERR(0, 8, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":9
 * import os
 * import io
 * from contextlib import contextmanager             # <<<<<<<<<<<<<<
 * from codecs import register_error
 * 
 */
  __pyx_t_2 = PyList_New(1); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 9, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_INCREF(__pyx_n_s_contextmanager);
  __Pyx_GIVEREF(__pyx_n_s_contextmanager);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_2, 0, __pyx_n_s_contextmanager)) __PYX_ERR(0, 9, __pyx_L1_error);
  __pyx_t_3 = __Pyx_Import(__pyx_n_s_contextlib, __pyx_t_2, 0); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 9, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __pyx_t_2 = __Pyx_ImportFrom(__pyx_t_3, __pyx_n_s_contextmanager); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 9, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_contextmanager, __pyx_t_2) < 0) __PYX_ERR(0, 9, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":10
 * import io
 * from contextlib import contextmanager
 * from codecs import register_error             # <<<<<<<<<<<<<<
 * 
 * from cpython.version cimport PY_MAJOR_VERSION, PY_MINOR_VERSION
 */
  __pyx_t_3 = PyList_New(1); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 10, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_INCREF(__pyx_n_s_register_error);
  __Pyx_GIVEREF(__pyx_n_s_register_error);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 0, __pyx_n_s_register_error)) __PYX_ERR(0, 10, __pyx_L1_error);
  __pyx_t_2 = __Pyx_Import(__pyx_n_s_codecs, __pyx_t_3, 0); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 10, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __pyx_t_3 = __Pyx_ImportFrom(__pyx_t_2, __pyx_n_s_register_error); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 10, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_register_error, __pyx_t_3) < 0) __PYX_ERR(0, 10, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":31
 * #####################################################################
 * # hard-coded constants
 * cdef int MAX_POS = (1 << 31) - 1             # <<<<<<<<<<<<<<
 * 
 * #################################################################
 */
  __pyx_v_5pysam_9libcutils_MAX_POS = 0x7fffffff;

  /* "pysam/libcutils.pyx":35
 * #################################################################
 * # Utility functions for quality string conversions
 * cpdef c_array.array qualitystring_to_array(input_str, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a qualitystring to an array of quality values."""
 *     if input_str is None:
 */
  __pyx_t_2 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_1qualitystring_to_array, 0, __pyx_n_s_qualitystring_to_array, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__17)); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 35, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_CyFunction_SetDefaultsTuple(__pyx_t_2, __pyx_tuple__18);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_qualitystring_to_array, __pyx_t_2) < 0) __PYX_ERR(0, 35, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":44
 * 
 * 
 * cpdef array_to_qualitystring(c_array.array qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert an array of quality values to a string."""
 *     if qualities is None:
 */
  __pyx_t_2 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_3array_to_qualitystring, 0, __pyx_n_s_array_to_qualitystring, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__20)); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 44, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_CyFunction_SetDefaultsTuple(__pyx_t_2, __pyx_tuple__18);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_array_to_qualitystring, __pyx_t_2) < 0) __PYX_ERR(0, 44, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":58
 * 
 * 
 * cpdef qualities_to_qualitystring(qualities, int offset=33):             # <<<<<<<<<<<<<<
 *     """convert a list or array of quality scores to the string
 *     representation used in the SAM format.
 */
  __pyx_t_2 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_5qualities_to_qualitystring, 0, __pyx_n_s_qualities_to_qualitystring, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__21)); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 58, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_CyFunction_SetDefaultsTuple(__pyx_t_2, __pyx_tuple__18);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_qualities_to_qualitystring, __pyx_t_2) < 0) __PYX_ERR(0, 58, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":89
 * 
 * # Codec error handler that just interprets each bad byte as ISO-8859-1.
 * def latin1_replace(exception):             # <<<<<<<<<<<<<<
 *     return (chr(exception.object[exception.start]), exception.end)
 * 
 */
  __pyx_t_2 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_7latin1_replace, 0, __pyx_n_s_latin1_replace, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__23)); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 89, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_latin1_replace, __pyx_t_2) < 0) __PYX_ERR(0, 89, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;

  /* "pysam/libcutils.pyx":92
 *     return (chr(exception.object[exception.start]), exception.end)
 * 
 * register_error('pysam.latin1replace', latin1_replace)             # <<<<<<<<<<<<<<
 * 
 * 
 */
  __Pyx_GetModuleGlobalName(__pyx_t_2, __pyx_n_s_register_error); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 92, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_GetModuleGlobalName(__pyx_t_3, __pyx_n_s_latin1_replace); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 92, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __pyx_t_4 = PyTuple_New(2); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 92, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_INCREF(__pyx_kp_u_pysam_latin1replace);
  __Pyx_GIVEREF(__pyx_kp_u_pysam_latin1replace);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_4, 0, __pyx_kp_u_pysam_latin1replace)) __PYX_ERR(0, 92, __pyx_L1_error);
  __Pyx_GIVEREF(__pyx_t_3);
  if (__Pyx_PyTuple_SET_ITEM(__pyx_t_4, 1, __pyx_t_3)) __PYX_ERR(0, 92, __pyx_L1_error);
  __pyx_t_3 = 0;
  __pyx_t_3 = __Pyx_PyObject_Call(__pyx_t_2, __pyx_t_4, NULL); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 92, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":95
 * 
 * 
 * cdef str ERROR_HANDLER = 'strict'             # <<<<<<<<<<<<<<
 * 
 * cpdef get_encoding_error_handler():
 */
  __Pyx_INCREF(__pyx_n_u_strict);
  __Pyx_XGOTREF(__pyx_v_5pysam_9libcutils_ERROR_HANDLER);
  __Pyx_DECREF_SET(__pyx_v_5pysam_9libcutils_ERROR_HANDLER, __pyx_n_u_strict);
  __Pyx_GIVEREF(__pyx_n_u_strict);

  /* "pysam/libcutils.pyx":97
 * cdef str ERROR_HANDLER = 'strict'
 * 
 * cpdef get_encoding_error_handler():             # <<<<<<<<<<<<<<
 *     return ERROR_HANDLER
 * 
 */
  __pyx_t_3 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_9get_encoding_error_handler, 0, __pyx_n_s_get_encoding_error_handler, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__24)); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 97, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_get_encoding_error_handler, __pyx_t_3) < 0) __PYX_ERR(0, 97, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":100
 *     return ERROR_HANDLER
 * 
 * cpdef set_encoding_error_handler(name):             # <<<<<<<<<<<<<<
 *     global ERROR_HANDLER
 *     previous = ERROR_HANDLER
 */
  __pyx_t_3 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_11set_encoding_error_handler, 0, __pyx_n_s_set_encoding_error_handler, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__26)); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 100, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_set_encoding_error_handler, __pyx_t_3) < 0) __PYX_ERR(0, 100, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":114
 * 
 * # filename encoding (adapted from lxml.etree.pyx)
 * cdef str FILENAME_ENCODING = sys.getfilesystemencoding() or sys.getdefaultencoding() or 'ascii'             # <<<<<<<<<<<<<<
 * cdef str TEXT_ENCODING = 'utf-8'
 * 
 */
  __Pyx_GetModuleGlobalName(__pyx_t_4, __pyx_n_s_sys); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __pyx_t_2 = __Pyx_PyObject_GetAttrStr(__pyx_t_4, __pyx_n_s_getfilesystemencoding); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  __pyx_t_4 = __Pyx_PyObject_CallNoArg(__pyx_t_2); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __pyx_t_5 = __Pyx_PyObject_IsTrue(__pyx_t_4); if (unlikely((__pyx_t_5 < 0))) __PYX_ERR(0, 114, __pyx_L1_error)
  if (!__pyx_t_5) {
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  } else {
    if (!(likely(PyUnicode_CheckExact(__pyx_t_4))||((__pyx_t_4) == Py_None) || __Pyx_RaiseUnexpectedTypeError("unicode", __pyx_t_4))) __PYX_ERR(0, 114, __pyx_L1_error)
    __Pyx_INCREF(__pyx_t_4);
    __pyx_t_3 = __pyx_t_4;
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
    goto __pyx_L2_bool_binop_done;
  }
  __Pyx_GetModuleGlobalName(__pyx_t_4, __pyx_n_s_sys); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __pyx_t_2 = __Pyx_PyObject_GetAttrStr(__pyx_t_4, __pyx_n_s_getdefaultencoding); if (unlikely(!__pyx_t_2)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_2);
  __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  __pyx_t_4 = __Pyx_PyObject_CallNoArg(__pyx_t_2); if (unlikely(!__pyx_t_4)) __PYX_ERR(0, 114, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_4);
  __Pyx_DECREF(__pyx_t_2); __pyx_t_2 = 0;
  __pyx_t_5 = __Pyx_PyObject_IsTrue(__pyx_t_4); if (unlikely((__pyx_t_5 < 0))) __PYX_ERR(0, 114, __pyx_L1_error)
  if (!__pyx_t_5) {
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
  } else {
    if (!(likely(PyUnicode_CheckExact(__pyx_t_4))||((__pyx_t_4) == Py_None) || __Pyx_RaiseUnexpectedTypeError("unicode", __pyx_t_4))) __PYX_ERR(0, 114, __pyx_L1_error)
    __Pyx_INCREF(__pyx_t_4);
    __pyx_t_3 = __pyx_t_4;
    __Pyx_DECREF(__pyx_t_4); __pyx_t_4 = 0;
    goto __pyx_L2_bool_binop_done;
  }
  __Pyx_INCREF(__pyx_n_u_ascii);
  __pyx_t_3 = __pyx_n_u_ascii;
  __pyx_L2_bool_binop_done:;
  __Pyx_XGOTREF(__pyx_v_5pysam_9libcutils_FILENAME_ENCODING);
  __Pyx_DECREF_SET(__pyx_v_5pysam_9libcutils_FILENAME_ENCODING, ((PyObject*)__pyx_t_3));
  __Pyx_GIVEREF(__pyx_t_3);
  __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":115
 * # filename encoding (adapted from lxml.etree.pyx)
 * cdef str FILENAME_ENCODING = sys.getfilesystemencoding() or sys.getdefaultencoding() or 'ascii'
 * cdef str TEXT_ENCODING = 'utf-8'             # <<<<<<<<<<<<<<
 * 
 * cdef bytes encode_filename(object filename):
 */
  __Pyx_INCREF(__pyx_kp_u_utf_8);
  __Pyx_XGOTREF(__pyx_v_5pysam_9libcutils_TEXT_ENCODING);
  __Pyx_DECREF_SET(__pyx_v_5pysam_9libcutils_TEXT_ENCODING, __pyx_kp_u_utf_8);
  __Pyx_GIVEREF(__pyx_kp_u_utf_8);

  /* "pysam/libcutils.pyx":177
 * 
 * 
 * cpdef parse_region(contig=None,             # <<<<<<<<<<<<<<
 *                    start=None,
 *                    stop=None,
 */
  __pyx_t_3 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_13parse_region, 0, __pyx_n_s_parse_region, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__28)); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 177, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_CyFunction_SetDefaultsTuple(__pyx_t_3, __pyx_tuple__29);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_parse_region, __pyx_t_3) < 0) __PYX_ERR(0, 177, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":275
 * 
 * 
 * def _pysam_dispatch(collection,             # <<<<<<<<<<<<<<
 *                     method,
 *                     args=None,
 */
  __pyx_t_3 = __Pyx_CyFunction_New(&__pyx_mdef_5pysam_9libcutils_15_pysam_dispatch, 0, __pyx_n_s_pysam_dispatch, NULL, __pyx_n_s_pysam_libcutils, __pyx_d, ((PyObject *)__pyx_codeobj__31)); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 275, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_CyFunction_SetDefaultsTuple(__pyx_t_3, __pyx_tuple__32);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_pysam_dispatch, __pyx_t_3) < 0) __PYX_ERR(0, 275, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":436
 * 
 * 
 * __all__ = [             # <<<<<<<<<<<<<<
 *     "qualitystring_to_array",
 *     "array_to_qualitystring",
 */
  __pyx_t_3 = PyList_New(5); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 436, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  __Pyx_INCREF(__pyx_n_u_qualitystring_to_array);
  __Pyx_GIVEREF(__pyx_n_u_qualitystring_to_array);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 0, __pyx_n_u_qualitystring_to_array)) __PYX_ERR(0, 436, __pyx_L1_error);
  __Pyx_INCREF(__pyx_n_u_array_to_qualitystring);
  __Pyx_GIVEREF(__pyx_n_u_array_to_qualitystring);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 1, __pyx_n_u_array_to_qualitystring)) __PYX_ERR(0, 436, __pyx_L1_error);
  __Pyx_INCREF(__pyx_n_u_qualities_to_qualitystring);
  __Pyx_GIVEREF(__pyx_n_u_qualities_to_qualitystring);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 2, __pyx_n_u_qualities_to_qualitystring)) __PYX_ERR(0, 436, __pyx_L1_error);
  __Pyx_INCREF(__pyx_n_u_get_encoding_error_handler);
  __Pyx_GIVEREF(__pyx_n_u_get_encoding_error_handler);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 3, __pyx_n_u_get_encoding_error_handler)) __PYX_ERR(0, 436, __pyx_L1_error);
  __Pyx_INCREF(__pyx_n_u_set_encoding_error_handler);
  __Pyx_GIVEREF(__pyx_n_u_set_encoding_error_handler);
  if (__Pyx_PyList_SET_ITEM(__pyx_t_3, 4, __pyx_n_u_set_encoding_error_handler)) __PYX_ERR(0, 436, __pyx_L1_error);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_all, __pyx_t_3) < 0) __PYX_ERR(0, 436, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /* "pysam/libcutils.pyx":1
 * # cython: language_level=3             # <<<<<<<<<<<<<<
 * import types
 * import sys
 */
  __pyx_t_3 = __Pyx_PyDict_NewPresized(0); if (unlikely(!__pyx_t_3)) __PYX_ERR(0, 1, __pyx_L1_error)
  __Pyx_GOTREF(__pyx_t_3);
  if (PyDict_SetItem(__pyx_d, __pyx_n_s_test, __pyx_t_3) < 0) __PYX_ERR(0, 1, __pyx_L1_error)
  __Pyx_DECREF(__pyx_t_3); __pyx_t_3 = 0;

  /*--- Wrapped vars code ---*/

  goto __pyx_L0;
  __pyx_L1_error:;
  __Pyx_XDECREF(__pyx_t_2);
  __Pyx_XDECREF(__pyx_t_3);
  __Pyx_XDECREF(__pyx_t_4);
  if (__pyx_m) {
    if (__pyx_d && stringtab_initialized) {
      __Pyx_AddTraceback("init pysam.libcutils", __pyx_clineno, __pyx_lineno, __pyx_filename);
    }
    #if !CYTHON_USE_MODULE_STATE
    Py_CLEAR(__pyx_m);
    #else
    Py_DECREF(__pyx_m);
    if (pystate_addmodule_run) {
      PyObject *tp, *value, *tb;
      PyErr_Fetch(&tp, &value, &tb);
      PyState_RemoveModule(&__pyx_moduledef);
      PyErr_Restore(tp, value, tb);
    }
    #endif
  } else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_ImportError, "init pysam.libcutils");
  }
  __pyx_L0:;
  __Pyx_RefNannyFinishContext();
  #if CYTHON_PEP489_MULTI_PHASE_INIT
  return (__pyx_m != NULL) ? 0 : -1;
  #elif PY_MAJOR_VERSION >= 3
  return __pyx_m;
  #else
  return;
  #endif
}
/* #### Code section: cleanup_globals ### */
/* #### Code section: cleanup_module ### */
/* #### Code section: main_method ### */
/* #### Code section: utility_code_pragmas ### */
#ifdef _MSC_VER
#pragma warning( push )
/* Warning 4127: conditional expression is constant
 * Cython uses constant conditional expressions to allow in inline functions to be optimized at
 * compile-time, so this warning is not useful
 */
#pragma warning( disable : 4127 )
#endif



/* #### Code section: utility_code_def ### */

/* --- Runtime support code --- */
/* Refnanny */
#if CYTHON_REFNANNY
static __Pyx_RefNannyAPIStruct *__Pyx_RefNannyImportAPI(const char *modname) {
    PyObject *m = NULL, *p = NULL;
    void *r = NULL;
    m = PyImport_ImportModule(modname);
    if (!m) goto end;
    p = PyObject_GetAttrString(m, "RefNannyAPI");
    if (!p) goto end;
    r = PyLong_AsVoidPtr(p);
end:
    Py_XDECREF(p);
    Py_XDECREF(m);
    return (__Pyx_RefNannyAPIStruct *)r;
}
#endif

/* PyErrExceptionMatches */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx_PyErr_ExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        if (__Pyx_PyErr_GivenExceptionMatches(exc_type, PyTuple_GET_ITEM(tuple, i))) return 1;
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_ExceptionMatchesInState(PyThreadState* tstate, PyObject* err) {
    int result;
    PyObject *exc_type;
#if PY_VERSION_HEX >= 0x030C00A6
    PyObject *current_exception = tstate->current_exception;
    if (unlikely(!current_exception)) return 0;
    exc_type = (PyObject*) Py_TYPE(current_exception);
    if (exc_type == err) return 1;
#else
    exc_type = tstate->curexc_type;
    if (exc_type == err) return 1;
    if (unlikely(!exc_type)) return 0;
#endif
    #if CYTHON_AVOID_BORROWED_REFS
    Py_INCREF(exc_type);
    #endif
    if (unlikely(PyTuple_Check(err))) {
        result = __Pyx_PyErr_ExceptionMatchesTuple(exc_type, err);
    } else {
        result = __Pyx_PyErr_GivenExceptionMatches(exc_type, err);
    }
    #if CYTHON_AVOID_BORROWED_REFS
    Py_DECREF(exc_type);
    #endif
    return result;
}
#endif

/* PyErrFetchRestore */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx_ErrRestoreInState(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
#if PY_VERSION_HEX >= 0x030C00A6
    PyObject *tmp_value;
    assert(type == NULL || (value != NULL && type == (PyObject*) Py_TYPE(value)));
    if (value) {
        #if CYTHON_COMPILING_IN_CPYTHON
        if (unlikely(((PyBaseExceptionObject*) value)->traceback != tb))
        #endif
            PyException_SetTraceback(value, tb);
    }
    tmp_value = tstate->current_exception;
    tstate->current_exception = value;
    Py_XDECREF(tmp_value);
#else
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    tmp_type = tstate->curexc_type;
    tmp_value = tstate->curexc_value;
    tmp_tb = tstate->curexc_traceback;
    tstate->curexc_type = type;
    tstate->curexc_value = value;
    tstate->curexc_traceback = tb;
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#endif
}
static CYTHON_INLINE void __Pyx_ErrFetchInState(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
#if PY_VERSION_HEX >= 0x030C00A6
    PyObject* exc_value;
    exc_value = tstate->current_exception;
    tstate->current_exception = 0;
    *value = exc_value;
    *type = NULL;
    *tb = NULL;
    if (exc_value) {
        *type = (PyObject*) Py_TYPE(exc_value);
        Py_INCREF(*type);
        #if CYTHON_COMPILING_IN_CPYTHON
        *tb = ((PyBaseExceptionObject*) exc_value)->traceback;
        Py_XINCREF(*tb);
        #else
        *tb = PyException_GetTraceback(exc_value);
        #endif
    }
#else
    *type = tstate->curexc_type;
    *value = tstate->curexc_value;
    *tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
#endif
}
#endif

/* PyObjectGetAttrStr */
#if CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStr(PyObject* obj, PyObject* attr_name) {
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_getattro))
        return tp->tp_getattro(obj, attr_name);
#if PY_MAJOR_VERSION < 3
    if (likely(tp->tp_getattr))
        return tp->tp_getattr(obj, PyString_AS_STRING(attr_name));
#endif
    return PyObject_GetAttr(obj, attr_name);
}
#endif

/* PyObjectGetAttrStrNoError */
static void __Pyx_PyObject_GetAttrStr_ClearAttributeError(void) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    if (likely(__Pyx_PyErr_ExceptionMatches(PyExc_AttributeError)))
        __Pyx_PyErr_Clear();
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_GetAttrStrNoError(PyObject* obj, PyObject* attr_name) {
    PyObject *result;
#if CYTHON_COMPILING_IN_CPYTHON && CYTHON_USE_TYPE_SLOTS && PY_VERSION_HEX >= 0x030700B1
    PyTypeObject* tp = Py_TYPE(obj);
    if (likely(tp->tp_getattro == PyObject_GenericGetAttr)) {
        return _PyObject_GenericGetAttrWithDict(obj, attr_name, NULL, 1);
    }
#endif
    result = __Pyx_PyObject_GetAttrStr(obj, attr_name);
    if (unlikely(!result)) {
        __Pyx_PyObject_GetAttrStr_ClearAttributeError();
    }
    return result;
}

/* GetBuiltinName */
static PyObject *__Pyx_GetBuiltinName(PyObject *name) {
    PyObject* result = __Pyx_PyObject_GetAttrStrNoError(__pyx_b, name);
    if (unlikely(!result) && !PyErr_Occurred()) {
        PyErr_Format(PyExc_NameError,
#if PY_MAJOR_VERSION >= 3
            "name '%U' is not defined", name);
#else
            "name '%.200s' is not defined", PyString_AS_STRING(name));
#endif
    }
    return result;
}

/* TupleAndListFromArray */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE void __Pyx_copy_object_array(PyObject *const *CYTHON_RESTRICT src, PyObject** CYTHON_RESTRICT dest, Py_ssize_t length) {
    PyObject *v;
    Py_ssize_t i;
    for (i = 0; i < length; i++) {
        v = dest[i] = src[i];
        Py_INCREF(v);
    }
}
static CYTHON_INLINE PyObject *
__Pyx_PyTuple_FromArray(PyObject *const *src, Py_ssize_t n)
{
    PyObject *res;
    if (n <= 0) {
        Py_INCREF(__pyx_empty_tuple);
        return __pyx_empty_tuple;
    }
    res = PyTuple_New(n);
    if (unlikely(res == NULL)) return NULL;
    __Pyx_copy_object_array(src, ((PyTupleObject*)res)->ob_item, n);
    return res;
}
static CYTHON_INLINE PyObject *
__Pyx_PyList_FromArray(PyObject *const *src, Py_ssize_t n)
{
    PyObject *res;
    if (n <= 0) {
        return PyList_New(0);
    }
    res = PyList_New(n);
    if (unlikely(res == NULL)) return NULL;
    __Pyx_copy_object_array(src, ((PyListObject*)res)->ob_item, n);
    return res;
}
#endif

/* BytesEquals */
static CYTHON_INLINE int __Pyx_PyBytes_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API
    return PyObject_RichCompareBool(s1, s2, equals);
#else
    if (s1 == s2) {
        return (equals == Py_EQ);
    } else if (PyBytes_CheckExact(s1) & PyBytes_CheckExact(s2)) {
        const char *ps1, *ps2;
        Py_ssize_t length = PyBytes_GET_SIZE(s1);
        if (length != PyBytes_GET_SIZE(s2))
            return (equals == Py_NE);
        ps1 = PyBytes_AS_STRING(s1);
        ps2 = PyBytes_AS_STRING(s2);
        if (ps1[0] != ps2[0]) {
            return (equals == Py_NE);
        } else if (length == 1) {
            return (equals == Py_EQ);
        } else {
            int result;
#if CYTHON_USE_UNICODE_INTERNALS && (PY_VERSION_HEX < 0x030B0000)
            Py_hash_t hash1, hash2;
            hash1 = ((PyBytesObject*)s1)->ob_shash;
            hash2 = ((PyBytesObject*)s2)->ob_shash;
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                return (equals == Py_NE);
            }
#endif
            result = memcmp(ps1, ps2, (size_t)length);
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & PyBytes_CheckExact(s2)) {
        return (equals == Py_NE);
    } else if ((s2 == Py_None) & PyBytes_CheckExact(s1)) {
        return (equals == Py_NE);
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
#endif
}

/* UnicodeEquals */
static CYTHON_INLINE int __Pyx_PyUnicode_Equals(PyObject* s1, PyObject* s2, int equals) {
#if CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API
    return PyObject_RichCompareBool(s1, s2, equals);
#else
#if PY_MAJOR_VERSION < 3
    PyObject* owned_ref = NULL;
#endif
    int s1_is_unicode, s2_is_unicode;
    if (s1 == s2) {
        goto return_eq;
    }
    s1_is_unicode = PyUnicode_CheckExact(s1);
    s2_is_unicode = PyUnicode_CheckExact(s2);
#if PY_MAJOR_VERSION < 3
    if ((s1_is_unicode & (!s2_is_unicode)) && PyString_CheckExact(s2)) {
        owned_ref = PyUnicode_FromObject(s2);
        if (unlikely(!owned_ref))
            return -1;
        s2 = owned_ref;
        s2_is_unicode = 1;
    } else if ((s2_is_unicode & (!s1_is_unicode)) && PyString_CheckExact(s1)) {
        owned_ref = PyUnicode_FromObject(s1);
        if (unlikely(!owned_ref))
            return -1;
        s1 = owned_ref;
        s1_is_unicode = 1;
    } else if (((!s2_is_unicode) & (!s1_is_unicode))) {
        return __Pyx_PyBytes_Equals(s1, s2, equals);
    }
#endif
    if (s1_is_unicode & s2_is_unicode) {
        Py_ssize_t length;
        int kind;
        void *data1, *data2;
        if (unlikely(__Pyx_PyUnicode_READY(s1) < 0) || unlikely(__Pyx_PyUnicode_READY(s2) < 0))
            return -1;
        length = __Pyx_PyUnicode_GET_LENGTH(s1);
        if (length != __Pyx_PyUnicode_GET_LENGTH(s2)) {
            goto return_ne;
        }
#if CYTHON_USE_UNICODE_INTERNALS
        {
            Py_hash_t hash1, hash2;
        #if CYTHON_PEP393_ENABLED
            hash1 = ((PyASCIIObject*)s1)->hash;
            hash2 = ((PyASCIIObject*)s2)->hash;
        #else
            hash1 = ((PyUnicodeObject*)s1)->hash;
            hash2 = ((PyUnicodeObject*)s2)->hash;
        #endif
            if (hash1 != hash2 && hash1 != -1 && hash2 != -1) {
                goto return_ne;
            }
        }
#endif
        kind = __Pyx_PyUnicode_KIND(s1);
        if (kind != __Pyx_PyUnicode_KIND(s2)) {
            goto return_ne;
        }
        data1 = __Pyx_PyUnicode_DATA(s1);
        data2 = __Pyx_PyUnicode_DATA(s2);
        if (__Pyx_PyUnicode_READ(kind, data1, 0) != __Pyx_PyUnicode_READ(kind, data2, 0)) {
            goto return_ne;
        } else if (length == 1) {
            goto return_eq;
        } else {
            int result = memcmp(data1, data2, (size_t)(length * kind));
            #if PY_MAJOR_VERSION < 3
            Py_XDECREF(owned_ref);
            #endif
            return (equals == Py_EQ) ? (result == 0) : (result != 0);
        }
    } else if ((s1 == Py_None) & s2_is_unicode) {
        goto return_ne;
    } else if ((s2 == Py_None) & s1_is_unicode) {
        goto return_ne;
    } else {
        int result;
        PyObject* py_result = PyObject_RichCompare(s1, s2, equals);
        #if PY_MAJOR_VERSION < 3
        Py_XDECREF(owned_ref);
        #endif
        if (!py_result)
            return -1;
        result = __Pyx_PyObject_IsTrue(py_result);
        Py_DECREF(py_result);
        return result;
    }
return_eq:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_EQ);
return_ne:
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(owned_ref);
    #endif
    return (equals == Py_NE);
#endif
}

/* fastcall */
#if CYTHON_METH_FASTCALL
static CYTHON_INLINE PyObject * __Pyx_GetKwValue_FASTCALL(PyObject *kwnames, PyObject *const *kwvalues, PyObject *s)
{
    Py_ssize_t i, n = PyTuple_GET_SIZE(kwnames);
    for (i = 0; i < n; i++)
    {
        if (s == PyTuple_GET_ITEM(kwnames, i)) return kwvalues[i];
    }
    for (i = 0; i < n; i++)
    {
        int eq = __Pyx_PyUnicode_Equals(s, PyTuple_GET_ITEM(kwnames, i), Py_EQ);
        if (unlikely(eq != 0)) {
            if (unlikely(eq < 0)) return NULL;  // error
            return kwvalues[i];
        }
    }
    return NULL;  // not found (no exception set)
}
#endif

/* PyObjectCall */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *result;
    ternaryfunc call = Py_TYPE(func)->tp_call;
    if (unlikely(!call))
        return PyObject_Call(func, arg, kw);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = (*call)(func, arg, kw);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* RaiseDoubleKeywords */
static void __Pyx_RaiseDoubleKeywordsError(
    const char* func_name,
    PyObject* kw_name)
{
    PyErr_Format(PyExc_TypeError,
        #if PY_MAJOR_VERSION >= 3
        "%s() got multiple values for keyword argument '%U'", func_name, kw_name);
        #else
        "%s() got multiple values for keyword argument '%s'", func_name,
        PyString_AsString(kw_name));
        #endif
}

/* ParseKeywords */
static int __Pyx_ParseOptionalKeywords(
    PyObject *kwds,
    PyObject *const *kwvalues,
    PyObject **argnames[],
    PyObject *kwds2,
    PyObject *values[],
    Py_ssize_t num_pos_args,
    const char* function_name)
{
    PyObject *key = 0, *value = 0;
    Py_ssize_t pos = 0;
    PyObject*** name;
    PyObject*** first_kw_arg = argnames + num_pos_args;
    int kwds_is_tuple = CYTHON_METH_FASTCALL && likely(PyTuple_Check(kwds));
    while (1) {
        Py_XDECREF(key); key = NULL;
        Py_XDECREF(value); value = NULL;
        if (kwds_is_tuple) {
            Py_ssize_t size;
#if CYTHON_ASSUME_SAFE_MACROS
            size = PyTuple_GET_SIZE(kwds);
#else
            size = PyTuple_Size(kwds);
            if (size < 0) goto bad;
#endif
            if (pos >= size) break;
#if CYTHON_AVOID_BORROWED_REFS
            key = __Pyx_PySequence_ITEM(kwds, pos);
            if (!key) goto bad;
#elif CYTHON_ASSUME_SAFE_MACROS
            key = PyTuple_GET_ITEM(kwds, pos);
#else
            key = PyTuple_GetItem(kwds, pos);
            if (!key) goto bad;
#endif
            value = kwvalues[pos];
            pos++;
        }
        else
        {
            if (!PyDict_Next(kwds, &pos, &key, &value)) break;
#if CYTHON_AVOID_BORROWED_REFS
            Py_INCREF(key);
#endif
        }
        name = first_kw_arg;
        while (*name && (**name != key)) name++;
        if (*name) {
            values[name-argnames] = value;
#if CYTHON_AVOID_BORROWED_REFS
            Py_INCREF(value); // transfer ownership of value to values
            Py_DECREF(key);
#endif
            key = NULL;
            value = NULL;
            continue;
        }
#if !CYTHON_AVOID_BORROWED_REFS
        Py_INCREF(key);
#endif
        Py_INCREF(value);
        name = first_kw_arg;
        #if PY_MAJOR_VERSION < 3
        if (likely(PyString_Check(key))) {
            while (*name) {
                if ((CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**name) == PyString_GET_SIZE(key))
                        && _PyString_Eq(**name, key)) {
                    values[name-argnames] = value;
#if CYTHON_AVOID_BORROWED_REFS
                    value = NULL;  // ownership transferred to values
#endif
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    if ((**argname == key) || (
                            (CYTHON_COMPILING_IN_PYPY || PyString_GET_SIZE(**argname) == PyString_GET_SIZE(key))
                             && _PyString_Eq(**argname, key))) {
                        goto arg_passed_twice;
                    }
                    argname++;
                }
            }
        } else
        #endif
        if (likely(PyUnicode_Check(key))) {
            while (*name) {
                int cmp = (
                #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                    (__Pyx_PyUnicode_GET_LENGTH(**name) != __Pyx_PyUnicode_GET_LENGTH(key)) ? 1 :
                #endif
                    PyUnicode_Compare(**name, key)
                );
                if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                if (cmp == 0) {
                    values[name-argnames] = value;
#if CYTHON_AVOID_BORROWED_REFS
                    value = NULL; // ownership transferred to values
#endif
                    break;
                }
                name++;
            }
            if (*name) continue;
            else {
                PyObject*** argname = argnames;
                while (argname != first_kw_arg) {
                    int cmp = (**argname == key) ? 0 :
                    #if !CYTHON_COMPILING_IN_PYPY && PY_MAJOR_VERSION >= 3
                        (__Pyx_PyUnicode_GET_LENGTH(**argname) != __Pyx_PyUnicode_GET_LENGTH(key)) ? 1 :
                    #endif
                        PyUnicode_Compare(**argname, key);
                    if (cmp < 0 && unlikely(PyErr_Occurred())) goto bad;
                    if (cmp == 0) goto arg_passed_twice;
                    argname++;
                }
            }
        } else
            goto invalid_keyword_type;
        if (kwds2) {
            if (unlikely(PyDict_SetItem(kwds2, key, value))) goto bad;
        } else {
            goto invalid_keyword;
        }
    }
    Py_XDECREF(key);
    Py_XDECREF(value);
    return 0;
arg_passed_twice:
    __Pyx_RaiseDoubleKeywordsError(function_name, key);
    goto bad;
invalid_keyword_type:
    PyErr_Format(PyExc_TypeError,
        "%.200s() keywords must be strings", function_name);
    goto bad;
invalid_keyword:
    #if PY_MAJOR_VERSION < 3
    PyErr_Format(PyExc_TypeError,
        "%.200s() got an unexpected keyword argument '%.200s'",
        function_name, PyString_AsString(key));
    #else
    PyErr_Format(PyExc_TypeError,
        "%s() got an unexpected keyword argument '%U'",
        function_name, key);
    #endif
bad:
    Py_XDECREF(key);
    Py_XDECREF(value);
    return -1;
}

/* RaiseArgTupleInvalid */
static void __Pyx_RaiseArgtupleInvalid(
    const char* func_name,
    int exact,
    Py_ssize_t num_min,
    Py_ssize_t num_max,
    Py_ssize_t num_found)
{
    Py_ssize_t num_expected;
    const char *more_or_less;
    if (num_found < num_min) {
        num_expected = num_min;
        more_or_less = "at least";
    } else {
        num_expected = num_max;
        more_or_less = "at most";
    }
    if (exact) {
        more_or_less = "exactly";
    }
    PyErr_Format(PyExc_TypeError,
                 "%.200s() takes %.8s %" CYTHON_FORMAT_SSIZE_T "d positional argument%.1s (%" CYTHON_FORMAT_SSIZE_T "d given)",
                 func_name, more_or_less, num_expected,
                 (num_expected == 1) ? "" : "s", num_found);
}

/* GetItemInt */
static PyObject *__Pyx_GetItemInt_Generic(PyObject *o, PyObject* j) {
    PyObject *r;
    if (unlikely(!j)) return NULL;
    r = PyObject_GetItem(o, j);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_List_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyList_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyList_GET_SIZE(o)))) {
        PyObject *r = PyList_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Tuple_Fast(PyObject *o, Py_ssize_t i,
                                                              CYTHON_NCP_UNUSED int wraparound,
                                                              CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    Py_ssize_t wrapped_i = i;
    if (wraparound & unlikely(i < 0)) {
        wrapped_i += PyTuple_GET_SIZE(o);
    }
    if ((!boundscheck) || likely(__Pyx_is_valid_index(wrapped_i, PyTuple_GET_SIZE(o)))) {
        PyObject *r = PyTuple_GET_ITEM(o, wrapped_i);
        Py_INCREF(r);
        return r;
    }
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
#else
    return PySequence_GetItem(o, i);
#endif
}
static CYTHON_INLINE PyObject *__Pyx_GetItemInt_Fast(PyObject *o, Py_ssize_t i, int is_list,
                                                     CYTHON_NCP_UNUSED int wraparound,
                                                     CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyList_GET_SIZE(o);
        if ((!boundscheck) || (likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o))))) {
            PyObject *r = PyList_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    }
    else if (PyTuple_CheckExact(o)) {
        Py_ssize_t n = ((!wraparound) | likely(i >= 0)) ? i : i + PyTuple_GET_SIZE(o);
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyTuple_GET_SIZE(o)))) {
            PyObject *r = PyTuple_GET_ITEM(o, n);
            Py_INCREF(r);
            return r;
        }
    } else {
        PyMappingMethods *mm = Py_TYPE(o)->tp_as_mapping;
        PySequenceMethods *sm = Py_TYPE(o)->tp_as_sequence;
        if (mm && mm->mp_subscript) {
            PyObject *r, *key = PyInt_FromSsize_t(i);
            if (unlikely(!key)) return NULL;
            r = mm->mp_subscript(o, key);
            Py_DECREF(key);
            return r;
        }
        if (likely(sm && sm->sq_item)) {
            if (wraparound && unlikely(i < 0) && likely(sm->sq_length)) {
                Py_ssize_t l = sm->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return NULL;
                    PyErr_Clear();
                }
            }
            return sm->sq_item(o, i);
        }
    }
#else
    if (is_list || PySequence_Check(o)) {
        return PySequence_GetItem(o, i);
    }
#endif
    return __Pyx_GetItemInt_Generic(o, PyInt_FromSsize_t(i));
}

/* SetItemInt */
static int __Pyx_SetItemInt_Generic(PyObject *o, PyObject *j, PyObject *v) {
    int r;
    if (unlikely(!j)) return -1;
    r = PyObject_SetItem(o, j, v);
    Py_DECREF(j);
    return r;
}
static CYTHON_INLINE int __Pyx_SetItemInt_Fast(PyObject *o, Py_ssize_t i, PyObject *v, int is_list,
                                               CYTHON_NCP_UNUSED int wraparound, CYTHON_NCP_UNUSED int boundscheck) {
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS && CYTHON_USE_TYPE_SLOTS
    if (is_list || PyList_CheckExact(o)) {
        Py_ssize_t n = (!wraparound) ? i : ((likely(i >= 0)) ? i : i + PyList_GET_SIZE(o));
        if ((!boundscheck) || likely(__Pyx_is_valid_index(n, PyList_GET_SIZE(o)))) {
            PyObject* old = PyList_GET_ITEM(o, n);
            Py_INCREF(v);
            PyList_SET_ITEM(o, n, v);
            Py_DECREF(old);
            return 1;
        }
    } else {
        PyMappingMethods *mm = Py_TYPE(o)->tp_as_mapping;
        PySequenceMethods *sm = Py_TYPE(o)->tp_as_sequence;
        if (mm && mm->mp_ass_subscript) {
            int r;
            PyObject *key = PyInt_FromSsize_t(i);
            if (unlikely(!key)) return -1;
            r = mm->mp_ass_subscript(o, key, v);
            Py_DECREF(key);
            return r;
        }
        if (likely(sm && sm->sq_ass_item)) {
            if (wraparound && unlikely(i < 0) && likely(sm->sq_length)) {
                Py_ssize_t l = sm->sq_length(o);
                if (likely(l >= 0)) {
                    i += l;
                } else {
                    if (!PyErr_ExceptionMatches(PyExc_OverflowError))
                        return -1;
                    PyErr_Clear();
                }
            }
            return sm->sq_ass_item(o, i, v);
        }
    }
#else
#if CYTHON_COMPILING_IN_PYPY
    if (is_list || (PySequence_Check(o) && !PyDict_Check(o)))
#else
    if (is_list || PySequence_Check(o))
#endif
    {
        return PySequence_SetItem(o, i, v);
    }
#endif
    return __Pyx_SetItemInt_Generic(o, PyInt_FromSsize_t(i), v);
}

/* PyFunctionFastCall */
#if CYTHON_FAST_PYCALL && !CYTHON_VECTORCALL
static PyObject* __Pyx_PyFunction_FastCallNoKw(PyCodeObject *co, PyObject **args, Py_ssize_t na,
                                               PyObject *globals) {
    PyFrameObject *f;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject **fastlocals;
    Py_ssize_t i;
    PyObject *result;
    assert(globals != NULL);
    /* XXX Perhaps we should create a specialized
       PyFrame_New() that doesn't take locals, but does
       take builtins without sanity checking them.
       */
    assert(tstate != NULL);
    f = PyFrame_New(tstate, co, globals, NULL);
    if (f == NULL) {
        return NULL;
    }
    fastlocals = __Pyx_PyFrame_GetLocalsplus(f);
    for (i = 0; i < na; i++) {
        Py_INCREF(*args);
        fastlocals[i] = *args++;
    }
    result = PyEval_EvalFrameEx(f,0);
    ++tstate->recursion_depth;
    Py_DECREF(f);
    --tstate->recursion_depth;
    return result;
}
static PyObject *__Pyx_PyFunction_FastCallDict(PyObject *func, PyObject **args, Py_ssize_t nargs, PyObject *kwargs) {
    PyCodeObject *co = (PyCodeObject *)PyFunction_GET_CODE(func);
    PyObject *globals = PyFunction_GET_GLOBALS(func);
    PyObject *argdefs = PyFunction_GET_DEFAULTS(func);
    PyObject *closure;
#if PY_MAJOR_VERSION >= 3
    PyObject *kwdefs;
#endif
    PyObject *kwtuple, **k;
    PyObject **d;
    Py_ssize_t nd;
    Py_ssize_t nk;
    PyObject *result;
    assert(kwargs == NULL || PyDict_Check(kwargs));
    nk = kwargs ? PyDict_Size(kwargs) : 0;
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object"))) {
        return NULL;
    }
    if (
#if PY_MAJOR_VERSION >= 3
            co->co_kwonlyargcount == 0 &&
#endif
            likely(kwargs == NULL || nk == 0) &&
            co->co_flags == (CO_OPTIMIZED | CO_NEWLOCALS | CO_NOFREE)) {
        if (argdefs == NULL && co->co_argcount == nargs) {
            result = __Pyx_PyFunction_FastCallNoKw(co, args, nargs, globals);
            goto done;
        }
        else if (nargs == 0 && argdefs != NULL
                 && co->co_argcount == Py_SIZE(argdefs)) {
            /* function called with no arguments, but all parameters have
               a default value: use default values as arguments .*/
            args = &PyTuple_GET_ITEM(argdefs, 0);
            result =__Pyx_PyFunction_FastCallNoKw(co, args, Py_SIZE(argdefs), globals);
            goto done;
        }
    }
    if (kwargs != NULL) {
        Py_ssize_t pos, i;
        kwtuple = PyTuple_New(2 * nk);
        if (kwtuple == NULL) {
            result = NULL;
            goto done;
        }
        k = &PyTuple_GET_ITEM(kwtuple, 0);
        pos = i = 0;
        while (PyDict_Next(kwargs, &pos, &k[i], &k[i+1])) {
            Py_INCREF(k[i]);
            Py_INCREF(k[i+1]);
            i += 2;
        }
        nk = i / 2;
    }
    else {
        kwtuple = NULL;
        k = NULL;
    }
    closure = PyFunction_GET_CLOSURE(func);
#if PY_MAJOR_VERSION >= 3
    kwdefs = PyFunction_GET_KW_DEFAULTS(func);
#endif
    if (argdefs != NULL) {
        d = &PyTuple_GET_ITEM(argdefs, 0);
        nd = Py_SIZE(argdefs);
    }
    else {
        d = NULL;
        nd = 0;
    }
#if PY_MAJOR_VERSION >= 3
    result = PyEval_EvalCodeEx((PyObject*)co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, kwdefs, closure);
#else
    result = PyEval_EvalCodeEx(co, globals, (PyObject *)NULL,
                               args, (int)nargs,
                               k, (int)nk,
                               d, (int)nd, closure);
#endif
    Py_XDECREF(kwtuple);
done:
    Py_LeaveRecursiveCall();
    return result;
}
#endif

/* PyObjectCallMethO */
#if CYTHON_COMPILING_IN_CPYTHON
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallMethO(PyObject *func, PyObject *arg) {
    PyObject *self, *result;
    PyCFunction cfunc;
    cfunc = PyCFunction_GET_FUNCTION(func);
    self = PyCFunction_GET_SELF(func);
    if (unlikely(Py_EnterRecursiveCall((char*)" while calling a Python object")))
        return NULL;
    result = cfunc(self, arg);
    Py_LeaveRecursiveCall();
    if (unlikely(!result) && unlikely(!PyErr_Occurred())) {
        PyErr_SetString(
            PyExc_SystemError,
            "NULL result without error in PyObject_Call");
    }
    return result;
}
#endif

/* PyObjectFastCall */
static PyObject* __Pyx_PyObject_FastCall_fallback(PyObject *func, PyObject **args, size_t nargs, PyObject *kwargs) {
    PyObject *argstuple;
    PyObject *result = 0;
    size_t i;
    argstuple = PyTuple_New((Py_ssize_t)nargs);
    if (unlikely(!argstuple)) return NULL;
    for (i = 0; i < nargs; i++) {
        Py_INCREF(args[i]);
        if (__Pyx_PyTuple_SET_ITEM(argstuple, (Py_ssize_t)i, args[i]) < 0) goto bad;
    }
    result = __Pyx_PyObject_Call(func, argstuple, kwargs);
  bad:
    Py_DECREF(argstuple);
    return result;
}
static CYTHON_INLINE PyObject* __Pyx_PyObject_FastCallDict(PyObject *func, PyObject **args, size_t _nargs, PyObject *kwargs) {
    Py_ssize_t nargs = __Pyx_PyVectorcall_NARGS(_nargs);
#if CYTHON_COMPILING_IN_CPYTHON
    if (nargs == 0 && kwargs == NULL) {
#if defined(__Pyx_CyFunction_USED) && defined(NDEBUG)
        if (__Pyx_IsCyOrPyCFunction(func))
#else
        if (PyCFunction_Check(func))
#endif
        {
            if (likely(PyCFunction_GET_FLAGS(func) & METH_NOARGS)) {
                return __Pyx_PyObject_CallMethO(func, NULL);
            }
        }
    }
    else if (nargs == 1 && kwargs == NULL) {
        if (PyCFunction_Check(func))
        {
            if (likely(PyCFunction_GET_FLAGS(func) & METH_O)) {
                return __Pyx_PyObject_CallMethO(func, args[0]);
            }
        }
    }
#endif
    #if PY_VERSION_HEX < 0x030800B1
    #if CYTHON_FAST_PYCCALL
    if (PyCFunction_Check(func)) {
        if (kwargs) {
            return _PyCFunction_FastCallDict(func, args, nargs, kwargs);
        } else {
            return _PyCFunction_FastCallKeywords(func, args, nargs, NULL);
        }
    }
    #if PY_VERSION_HEX >= 0x030700A1
    if (!kwargs && __Pyx_IS_TYPE(func, &PyMethodDescr_Type)) {
        return _PyMethodDescr_FastCallKeywords(func, args, nargs, NULL);
    }
    #endif
    #endif
    #if CYTHON_FAST_PYCALL
    if (PyFunction_Check(func)) {
        return __Pyx_PyFunction_FastCallDict(func, args, nargs, kwargs);
    }
    #endif
    #endif
    #if CYTHON_VECTORCALL
    #if Py_VERSION_HEX < 0x03090000
    vectorcallfunc f = _PyVectorcall_Function(func);
    #else
    vectorcallfunc f = PyVectorcall_Function(func);
    #endif
    if (f) {
        return f(func, args, (size_t)nargs, kwargs);
    }
    #elif defined(__Pyx_CyFunction_USED) && CYTHON_BACKPORT_VECTORCALL
    if (__Pyx_CyFunction_CheckExact(func)) {
        __pyx_vectorcallfunc f = __Pyx_CyFunction_func_vectorcall(func);
        if (f) return f(func, args, (size_t)nargs, kwargs);
    }
    #endif
    if (nargs == 0) {
        return __Pyx_PyObject_Call(func, __pyx_empty_tuple, kwargs);
    }
    return __Pyx_PyObject_FastCall_fallback(func, args, (size_t)nargs, kwargs);
}

/* ArgTypeTest */
static int __Pyx__ArgTypeTest(PyObject *obj, PyTypeObject *type, const char *name, int exact)
{
    __Pyx_TypeName type_name;
    __Pyx_TypeName obj_type_name;
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    else if (exact) {
        #if PY_MAJOR_VERSION == 2
        if ((type == &PyBaseString_Type) && likely(__Pyx_PyBaseString_CheckExact(obj))) return 1;
        #endif
    }
    else {
        if (likely(__Pyx_TypeCheck(obj, type))) return 1;
    }
    type_name = __Pyx_PyType_GetName(type);
    obj_type_name = __Pyx_PyType_GetName(Py_TYPE(obj));
    PyErr_Format(PyExc_TypeError,
        "Argument '%.200s' has incorrect type (expected " __Pyx_FMT_TYPENAME
        ", got " __Pyx_FMT_TYPENAME ")", name, type_name, obj_type_name);
    __Pyx_DECREF_TypeName(type_name);
    __Pyx_DECREF_TypeName(obj_type_name);
    return 0;
}

/* ExtTypeTest */
static CYTHON_INLINE int __Pyx_TypeTest(PyObject *obj, PyTypeObject *type) {
    __Pyx_TypeName obj_type_name;
    __Pyx_TypeName type_name;
    if (unlikely(!type)) {
        PyErr_SetString(PyExc_SystemError, "Missing type object");
        return 0;
    }
    if (likely(__Pyx_TypeCheck(obj, type)))
        return 1;
    obj_type_name = __Pyx_PyType_GetName(Py_TYPE(obj));
    type_name = __Pyx_PyType_GetName(type);
    PyErr_Format(PyExc_TypeError,
                 "Cannot convert " __Pyx_FMT_TYPENAME " to " __Pyx_FMT_TYPENAME,
                 obj_type_name, type_name);
    __Pyx_DECREF_TypeName(obj_type_name);
    __Pyx_DECREF_TypeName(type_name);
    return 0;
}

/* PyObjectCallOneArg */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallOneArg(PyObject *func, PyObject *arg) {
    PyObject *args[2] = {NULL, arg};
    return __Pyx_PyObject_FastCall(func, args+1, 1 | __Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET);
}

/* ObjectGetItem */
#if CYTHON_USE_TYPE_SLOTS
static PyObject *__Pyx_PyObject_GetIndex(PyObject *obj, PyObject *index) {
    PyObject *runerr = NULL;
    Py_ssize_t key_value;
    key_value = __Pyx_PyIndex_AsSsize_t(index);
    if (likely(key_value != -1 || !(runerr = PyErr_Occurred()))) {
        return __Pyx_GetItemInt_Fast(obj, key_value, 0, 1, 1);
    }
    if (PyErr_GivenExceptionMatches(runerr, PyExc_OverflowError)) {
        __Pyx_TypeName index_type_name = __Pyx_PyType_GetName(Py_TYPE(index));
        PyErr_Clear();
        PyErr_Format(PyExc_IndexError,
            "cannot fit '" __Pyx_FMT_TYPENAME "' into an index-sized integer", index_type_name);
        __Pyx_DECREF_TypeName(index_type_name);
    }
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem_Slow(PyObject *obj, PyObject *key) {
    __Pyx_TypeName obj_type_name;
    if (likely(PyType_Check(obj))) {
        PyObject *meth = __Pyx_PyObject_GetAttrStrNoError(obj, __pyx_n_s_class_getitem);
        if (meth) {
            PyObject *result = __Pyx_PyObject_CallOneArg(meth, key);
            Py_DECREF(meth);
            return result;
        }
    }
    obj_type_name = __Pyx_PyType_GetName(Py_TYPE(obj));
    PyErr_Format(PyExc_TypeError,
        "'" __Pyx_FMT_TYPENAME "' object is not subscriptable", obj_type_name);
    __Pyx_DECREF_TypeName(obj_type_name);
    return NULL;
}
static PyObject *__Pyx_PyObject_GetItem(PyObject *obj, PyObject *key) {
    PyTypeObject *tp = Py_TYPE(obj);
    PyMappingMethods *mm = tp->tp_as_mapping;
    PySequenceMethods *sm = tp->tp_as_sequence;
    if (likely(mm && mm->mp_subscript)) {
        return mm->mp_subscript(obj, key);
    }
    if (likely(sm && sm->sq_item)) {
        return __Pyx_PyObject_GetIndex(obj, key);
    }
    return __Pyx_PyObject_GetItem_Slow(obj, key);
}
#endif

/* RaiseUnexpectedTypeError */
static int
__Pyx_RaiseUnexpectedTypeError(const char *expected, PyObject *obj)
{
    __Pyx_TypeName obj_type_name = __Pyx_PyType_GetName(Py_TYPE(obj));
    PyErr_Format(PyExc_TypeError, "Expected %s, got " __Pyx_FMT_TYPENAME,
                 expected, obj_type_name);
    __Pyx_DECREF_TypeName(obj_type_name);
    return 0;
}

/* PyDictVersioning */
#if CYTHON_USE_DICT_VERSIONS && CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PY_UINT64_T __Pyx_get_tp_dict_version(PyObject *obj) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    return likely(dict) ? __PYX_GET_DICT_VERSION(dict) : 0;
}
static CYTHON_INLINE PY_UINT64_T __Pyx_get_object_dict_version(PyObject *obj) {
    PyObject **dictptr = NULL;
    Py_ssize_t offset = Py_TYPE(obj)->tp_dictoffset;
    if (offset) {
#if CYTHON_COMPILING_IN_CPYTHON
        dictptr = (likely(offset > 0)) ? (PyObject **) ((char *)obj + offset) : _PyObject_GetDictPtr(obj);
#else
        dictptr = _PyObject_GetDictPtr(obj);
#endif
    }
    return (dictptr && *dictptr) ? __PYX_GET_DICT_VERSION(*dictptr) : 0;
}
static CYTHON_INLINE int __Pyx_object_dict_version_matches(PyObject* obj, PY_UINT64_T tp_dict_version, PY_UINT64_T obj_dict_version) {
    PyObject *dict = Py_TYPE(obj)->tp_dict;
    if (unlikely(!dict) || unlikely(tp_dict_version != __PYX_GET_DICT_VERSION(dict)))
        return 0;
    return obj_dict_version == __Pyx_get_object_dict_version(obj);
}
#endif

/* GetModuleGlobalName */
#if CYTHON_USE_DICT_VERSIONS
static PyObject *__Pyx__GetModuleGlobalName(PyObject *name, PY_UINT64_T *dict_version, PyObject **dict_cached_value)
#else
static CYTHON_INLINE PyObject *__Pyx__GetModuleGlobalName(PyObject *name)
#endif
{
    PyObject *result;
#if !CYTHON_AVOID_BORROWED_REFS
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030500A1
    result = _PyDict_GetItem_KnownHash(__pyx_d, name, ((PyASCIIObject *) name)->hash);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    } else if (unlikely(PyErr_Occurred())) {
        return NULL;
    }
#elif CYTHON_COMPILING_IN_LIMITED_API
    if (unlikely(!__pyx_m)) {
        return NULL;
    }
    result = PyObject_GetAttr(__pyx_m, name);
    if (likely(result)) {
        return result;
    }
#else
    result = PyDict_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
#endif
#else
    result = PyObject_GetItem(__pyx_d, name);
    __PYX_UPDATE_DICT_CACHE(__pyx_d, result, *dict_cached_value, *dict_version)
    if (likely(result)) {
        return __Pyx_NewRef(result);
    }
    PyErr_Clear();
#endif
    return __Pyx_GetBuiltinName(name);
}

/* RaiseException */
#if PY_MAJOR_VERSION < 3
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    __Pyx_PyThreadState_declare
    CYTHON_UNUSED_VAR(cause);
    Py_XINCREF(type);
    if (!value || value == Py_None)
        value = NULL;
    else
        Py_INCREF(value);
    if (!tb || tb == Py_None)
        tb = NULL;
    else {
        Py_INCREF(tb);
        if (!PyTraceBack_Check(tb)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: arg 3 must be a traceback or None");
            goto raise_error;
        }
    }
    if (PyType_Check(type)) {
#if CYTHON_COMPILING_IN_PYPY
        if (!value) {
            Py_INCREF(Py_None);
            value = Py_None;
        }
#endif
        PyErr_NormalizeException(&type, &value, &tb);
    } else {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto raise_error;
        }
        value = type;
        type = (PyObject*) Py_TYPE(type);
        Py_INCREF(type);
        if (!PyType_IsSubtype((PyTypeObject *)type, (PyTypeObject *)PyExc_BaseException)) {
            PyErr_SetString(PyExc_TypeError,
                "raise: exception class must be a subclass of BaseException");
            goto raise_error;
        }
    }
    __Pyx_PyThreadState_assign
    __Pyx_ErrRestore(type, value, tb);
    return;
raise_error:
    Py_XDECREF(value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
    return;
}
#else
static void __Pyx_Raise(PyObject *type, PyObject *value, PyObject *tb, PyObject *cause) {
    PyObject* owned_instance = NULL;
    if (tb == Py_None) {
        tb = 0;
    } else if (tb && !PyTraceBack_Check(tb)) {
        PyErr_SetString(PyExc_TypeError,
            "raise: arg 3 must be a traceback or None");
        goto bad;
    }
    if (value == Py_None)
        value = 0;
    if (PyExceptionInstance_Check(type)) {
        if (value) {
            PyErr_SetString(PyExc_TypeError,
                "instance exception may not have a separate value");
            goto bad;
        }
        value = type;
        type = (PyObject*) Py_TYPE(value);
    } else if (PyExceptionClass_Check(type)) {
        PyObject *instance_class = NULL;
        if (value && PyExceptionInstance_Check(value)) {
            instance_class = (PyObject*) Py_TYPE(value);
            if (instance_class != type) {
                int is_subclass = PyObject_IsSubclass(instance_class, type);
                if (!is_subclass) {
                    instance_class = NULL;
                } else if (unlikely(is_subclass == -1)) {
                    goto bad;
                } else {
                    type = instance_class;
                }
            }
        }
        if (!instance_class) {
            PyObject *args;
            if (!value)
                args = PyTuple_New(0);
            else if (PyTuple_Check(value)) {
                Py_INCREF(value);
                args = value;
            } else
                args = PyTuple_Pack(1, value);
            if (!args)
                goto bad;
            owned_instance = PyObject_Call(type, args, NULL);
            Py_DECREF(args);
            if (!owned_instance)
                goto bad;
            value = owned_instance;
            if (!PyExceptionInstance_Check(value)) {
                PyErr_Format(PyExc_TypeError,
                             "calling %R should have returned an instance of "
                             "BaseException, not %R",
                             type, Py_TYPE(value));
                goto bad;
            }
        }
    } else {
        PyErr_SetString(PyExc_TypeError,
            "raise: exception class must be a subclass of BaseException");
        goto bad;
    }
    if (cause) {
        PyObject *fixed_cause;
        if (cause == Py_None) {
            fixed_cause = NULL;
        } else if (PyExceptionClass_Check(cause)) {
            fixed_cause = PyObject_CallObject(cause, NULL);
            if (fixed_cause == NULL)
                goto bad;
        } else if (PyExceptionInstance_Check(cause)) {
            fixed_cause = cause;
            Py_INCREF(fixed_cause);
        } else {
            PyErr_SetString(PyExc_TypeError,
                            "exception causes must derive from "
                            "BaseException");
            goto bad;
        }
        PyException_SetCause(value, fixed_cause);
    }
    PyErr_SetObject(type, value);
    if (tb) {
      #if PY_VERSION_HEX >= 0x030C00A6
        PyException_SetTraceback(value, tb);
      #elif CYTHON_FAST_THREAD_STATE
        PyThreadState *tstate = __Pyx_PyThreadState_Current;
        PyObject* tmp_tb = tstate->curexc_traceback;
        if (tb != tmp_tb) {
            Py_INCREF(tb);
            tstate->curexc_traceback = tb;
            Py_XDECREF(tmp_tb);
        }
#else
        PyObject *tmp_type, *tmp_value, *tmp_tb;
        PyErr_Fetch(&tmp_type, &tmp_value, &tmp_tb);
        Py_INCREF(tb);
        PyErr_Restore(tmp_type, tmp_value, tb);
        Py_XDECREF(tmp_tb);
#endif
    }
bad:
    Py_XDECREF(owned_instance);
    return;
}
#endif

/* GetTopmostException */
#if CYTHON_USE_EXC_INFO_STACK && CYTHON_FAST_THREAD_STATE
static _PyErr_StackItem *
__Pyx_PyErr_GetTopmostException(PyThreadState *tstate)
{
    _PyErr_StackItem *exc_info = tstate->exc_info;
    while ((exc_info->exc_value == NULL || exc_info->exc_value == Py_None) &&
           exc_info->previous_item != NULL)
    {
        exc_info = exc_info->previous_item;
    }
    return exc_info;
}
#endif

/* SaveResetException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSave(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
  #if CYTHON_USE_EXC_INFO_STACK && PY_VERSION_HEX >= 0x030B00a4
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    PyObject *exc_value = exc_info->exc_value;
    if (exc_value == NULL || exc_value == Py_None) {
        *value = NULL;
        *type = NULL;
        *tb = NULL;
    } else {
        *value = exc_value;
        Py_INCREF(*value);
        *type = (PyObject*) Py_TYPE(exc_value);
        Py_INCREF(*type);
        *tb = PyException_GetTraceback(exc_value);
    }
  #elif CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = __Pyx_PyErr_GetTopmostException(tstate);
    *type = exc_info->exc_type;
    *value = exc_info->exc_value;
    *tb = exc_info->exc_traceback;
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
  #else
    *type = tstate->exc_type;
    *value = tstate->exc_value;
    *tb = tstate->exc_traceback;
    Py_XINCREF(*type);
    Py_XINCREF(*value);
    Py_XINCREF(*tb);
  #endif
}
static CYTHON_INLINE void __Pyx__ExceptionReset(PyThreadState *tstate, PyObject *type, PyObject *value, PyObject *tb) {
  #if CYTHON_USE_EXC_INFO_STACK && PY_VERSION_HEX >= 0x030B00a4
    _PyErr_StackItem *exc_info = tstate->exc_info;
    PyObject *tmp_value = exc_info->exc_value;
    exc_info->exc_value = value;
    Py_XDECREF(tmp_value);
    Py_XDECREF(type);
    Py_XDECREF(tb);
  #else
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    #if CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = type;
    exc_info->exc_value = value;
    exc_info->exc_traceback = tb;
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = type;
    tstate->exc_value = value;
    tstate->exc_traceback = tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
  #endif
}
#endif

/* GetException */
#if CYTHON_FAST_THREAD_STATE
static int __Pyx__GetException(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb)
#else
static int __Pyx_GetException(PyObject **type, PyObject **value, PyObject **tb)
#endif
{
    PyObject *local_type = NULL, *local_value, *local_tb = NULL;
#if CYTHON_FAST_THREAD_STATE
    PyObject *tmp_type, *tmp_value, *tmp_tb;
  #if PY_VERSION_HEX >= 0x030C00A6
    local_value = tstate->current_exception;
    tstate->current_exception = 0;
    if (likely(local_value)) {
        local_type = (PyObject*) Py_TYPE(local_value);
        Py_INCREF(local_type);
        local_tb = PyException_GetTraceback(local_value);
    }
  #else
    local_type = tstate->curexc_type;
    local_value = tstate->curexc_value;
    local_tb = tstate->curexc_traceback;
    tstate->curexc_type = 0;
    tstate->curexc_value = 0;
    tstate->curexc_traceback = 0;
  #endif
#else
    PyErr_Fetch(&local_type, &local_value, &local_tb);
#endif
    PyErr_NormalizeException(&local_type, &local_value, &local_tb);
#if CYTHON_FAST_THREAD_STATE && PY_VERSION_HEX >= 0x030C00A6
    if (unlikely(tstate->current_exception))
#elif CYTHON_FAST_THREAD_STATE
    if (unlikely(tstate->curexc_type))
#else
    if (unlikely(PyErr_Occurred()))
#endif
        goto bad;
    #if PY_MAJOR_VERSION >= 3
    if (local_tb) {
        if (unlikely(PyException_SetTraceback(local_value, local_tb) < 0))
            goto bad;
    }
    #endif
    Py_XINCREF(local_tb);
    Py_XINCREF(local_type);
    Py_XINCREF(local_value);
    *type = local_type;
    *value = local_value;
    *tb = local_tb;
#if CYTHON_FAST_THREAD_STATE
    #if CYTHON_USE_EXC_INFO_STACK
    {
        _PyErr_StackItem *exc_info = tstate->exc_info;
      #if PY_VERSION_HEX >= 0x030B00a4
        tmp_value = exc_info->exc_value;
        exc_info->exc_value = local_value;
        tmp_type = NULL;
        tmp_tb = NULL;
        Py_XDECREF(local_type);
        Py_XDECREF(local_tb);
      #else
        tmp_type = exc_info->exc_type;
        tmp_value = exc_info->exc_value;
        tmp_tb = exc_info->exc_traceback;
        exc_info->exc_type = local_type;
        exc_info->exc_value = local_value;
        exc_info->exc_traceback = local_tb;
      #endif
    }
    #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = local_type;
    tstate->exc_value = local_value;
    tstate->exc_traceback = local_tb;
    #endif
    Py_XDECREF(tmp_type);
    Py_XDECREF(tmp_value);
    Py_XDECREF(tmp_tb);
#else
    PyErr_SetExcInfo(local_type, local_value, local_tb);
#endif
    return 0;
bad:
    *type = 0;
    *value = 0;
    *tb = 0;
    Py_XDECREF(local_type);
    Py_XDECREF(local_value);
    Py_XDECREF(local_tb);
    return -1;
}

/* RaiseTooManyValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseTooManyValuesError(Py_ssize_t expected) {
    PyErr_Format(PyExc_ValueError,
                 "too many values to unpack (expected %" CYTHON_FORMAT_SSIZE_T "d)", expected);
}

/* RaiseNeedMoreValuesToUnpack */
static CYTHON_INLINE void __Pyx_RaiseNeedMoreValuesError(Py_ssize_t index) {
    PyErr_Format(PyExc_ValueError,
                 "need more than %" CYTHON_FORMAT_SSIZE_T "d value%.1s to unpack",
                 index, (index == 1) ? "" : "s");
}

/* IterFinish */
static CYTHON_INLINE int __Pyx_IterFinish(void) {
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    PyObject* exc_type = __Pyx_PyErr_CurrentExceptionType();
    if (unlikely(exc_type)) {
        if (unlikely(!__Pyx_PyErr_GivenExceptionMatches(exc_type, PyExc_StopIteration)))
            return -1;
        __Pyx_PyErr_Clear();
        return 0;
    }
    return 0;
}

/* UnpackItemEndCheck */
static int __Pyx_IternextUnpackEndCheck(PyObject *retval, Py_ssize_t expected) {
    if (unlikely(retval)) {
        Py_DECREF(retval);
        __Pyx_RaiseTooManyValuesError(expected);
        return -1;
    }
    return __Pyx_IterFinish();
}

/* PyIntBinop */
#if !CYTHON_COMPILING_IN_PYPY
static PyObject* __Pyx_PyInt_SubtractObjC(PyObject *op1, PyObject *op2, long intval, int inplace, int zerodivision_check) {
    CYTHON_MAYBE_UNUSED_VAR(intval);
    CYTHON_MAYBE_UNUSED_VAR(inplace);
    CYTHON_UNUSED_VAR(zerodivision_check);
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long x;
        long a = PyInt_AS_LONG(op1);
        
            x = (long)((unsigned long)a - (unsigned long)b);
            if (likely((x^a) >= 0 || (x^~b) >= 0))
                return PyInt_FromLong(x);
            return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        const long b = intval;
        long a, x;
#ifdef HAVE_LONG_LONG
        const PY_LONG_LONG llb = intval;
        PY_LONG_LONG lla, llx;
#endif
        if (unlikely(__Pyx_PyLong_IsZero(op1))) {
            return PyLong_FromLong(-intval);
        }
        if (likely(__Pyx_PyLong_IsCompact(op1))) {
            a = __Pyx_PyLong_CompactValue(op1);
        } else {
            const digit* digits = __Pyx_PyLong_Digits(op1);
            const Py_ssize_t size = __Pyx_PyLong_SignedDigitCount(op1);
            switch (size) {
                case -2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                case 2:
                    if (8 * sizeof(long) - 1 > 2 * PyLong_SHIFT) {
                        a = (long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 2 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                case -3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                case 3:
                    if (8 * sizeof(long) - 1 > 3 * PyLong_SHIFT) {
                        a = (long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 3 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                case -4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = -(PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                case 4:
                    if (8 * sizeof(long) - 1 > 4 * PyLong_SHIFT) {
                        a = (long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0]));
                        break;
                    #ifdef HAVE_LONG_LONG
                    } else if (8 * sizeof(PY_LONG_LONG) - 1 > 4 * PyLong_SHIFT) {
                        lla = (PY_LONG_LONG) (((((((((unsigned PY_LONG_LONG)digits[3]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[2]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[1]) << PyLong_SHIFT) | (unsigned PY_LONG_LONG)digits[0]));
                        goto long_long;
                    #endif
                    }
                    CYTHON_FALLTHROUGH;
                default: return PyLong_Type.tp_as_number->nb_subtract(op1, op2);
            }
        }
                x = a - b;
            return PyLong_FromLong(x);
#ifdef HAVE_LONG_LONG
        long_long:
                llx = lla - llb;
            return PyLong_FromLongLong(llx);
#endif
        
        
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
#if CYTHON_COMPILING_IN_LIMITED_API
        double a = __pyx_PyFloat_AsDouble(op1);
#else
        double a = PyFloat_AS_DOUBLE(op1);
#endif
            double result;
            
            PyFPE_START_PROTECT("subtract", return NULL)
            result = ((double)a) - (double)b;
            PyFPE_END_PROTECT(result)
            return PyFloat_FromDouble(result);
    }
    return (inplace ? PyNumber_InPlaceSubtract : PyNumber_Subtract)(op1, op2);
}
#endif

/* PyObjectLookupSpecial */
#if CYTHON_USE_PYTYPE_LOOKUP && CYTHON_USE_TYPE_SLOTS
static CYTHON_INLINE PyObject* __Pyx__PyObject_LookupSpecial(PyObject* obj, PyObject* attr_name, int with_error) {
    PyObject *res;
    PyTypeObject *tp = Py_TYPE(obj);
#if PY_MAJOR_VERSION < 3
    if (unlikely(PyInstance_Check(obj)))
        return with_error ? __Pyx_PyObject_GetAttrStr(obj, attr_name) : __Pyx_PyObject_GetAttrStrNoError(obj, attr_name);
#endif
    res = _PyType_Lookup(tp, attr_name);
    if (likely(res)) {
        descrgetfunc f = Py_TYPE(res)->tp_descr_get;
        if (!f) {
            Py_INCREF(res);
        } else {
            res = f(res, obj, (PyObject *)tp);
        }
    } else if (with_error) {
        PyErr_SetObject(PyExc_AttributeError, attr_name);
    }
    return res;
}
#endif

/* SwapException */
#if CYTHON_FAST_THREAD_STATE
static CYTHON_INLINE void __Pyx__ExceptionSwap(PyThreadState *tstate, PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
  #if CYTHON_USE_EXC_INFO_STACK && PY_VERSION_HEX >= 0x030B00a4
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_value = exc_info->exc_value;
    exc_info->exc_value = *value;
    if (tmp_value == NULL || tmp_value == Py_None) {
        Py_XDECREF(tmp_value);
        tmp_value = NULL;
        tmp_type = NULL;
        tmp_tb = NULL;
    } else {
        tmp_type = (PyObject*) Py_TYPE(tmp_value);
        Py_INCREF(tmp_type);
        #if CYTHON_COMPILING_IN_CPYTHON
        tmp_tb = ((PyBaseExceptionObject*) tmp_value)->traceback;
        Py_XINCREF(tmp_tb);
        #else
        tmp_tb = PyException_GetTraceback(tmp_value);
        #endif
    }
  #elif CYTHON_USE_EXC_INFO_STACK
    _PyErr_StackItem *exc_info = tstate->exc_info;
    tmp_type = exc_info->exc_type;
    tmp_value = exc_info->exc_value;
    tmp_tb = exc_info->exc_traceback;
    exc_info->exc_type = *type;
    exc_info->exc_value = *value;
    exc_info->exc_traceback = *tb;
  #else
    tmp_type = tstate->exc_type;
    tmp_value = tstate->exc_value;
    tmp_tb = tstate->exc_traceback;
    tstate->exc_type = *type;
    tstate->exc_value = *value;
    tstate->exc_traceback = *tb;
  #endif
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#else
static CYTHON_INLINE void __Pyx_ExceptionSwap(PyObject **type, PyObject **value, PyObject **tb) {
    PyObject *tmp_type, *tmp_value, *tmp_tb;
    PyErr_GetExcInfo(&tmp_type, &tmp_value, &tmp_tb);
    PyErr_SetExcInfo(*type, *value, *tb);
    *type = tmp_type;
    *value = tmp_value;
    *tb = tmp_tb;
}
#endif

/* PyIntCompare */
static CYTHON_INLINE int __Pyx_PyInt_BoolEqObjC(PyObject *op1, PyObject *op2, long intval, long inplace) {
    CYTHON_MAYBE_UNUSED_VAR(intval);
    CYTHON_UNUSED_VAR(inplace);
    if (op1 == op2) {
        return 1;
    }
    #if PY_MAJOR_VERSION < 3
    if (likely(PyInt_CheckExact(op1))) {
        const long b = intval;
        long a = PyInt_AS_LONG(op1);
        return (a == b);
    }
    #endif
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(PyLong_CheckExact(op1))) {
        int unequal;
        unsigned long uintval;
        Py_ssize_t size = __Pyx_PyLong_DigitCount(op1);
        const digit* digits = __Pyx_PyLong_Digits(op1);
        if (intval == 0) {
            return (__Pyx_PyLong_IsZero(op1) == 1);
        } else if (intval < 0) {
            if (__Pyx_PyLong_IsNonNeg(op1))
                return 0;
            intval = -intval;
        } else {
            if (__Pyx_PyLong_IsNeg(op1))
                return 0;
        }
        uintval = (unsigned long) intval;
#if PyLong_SHIFT * 4 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 4)) {
            unequal = (size != 5) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[4] != ((uintval >> (4 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 3 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 3)) {
            unequal = (size != 4) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[3] != ((uintval >> (3 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 2 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 2)) {
            unequal = (size != 3) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK)) | (digits[2] != ((uintval >> (2 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
#if PyLong_SHIFT * 1 < SIZEOF_LONG*8
        if (uintval >> (PyLong_SHIFT * 1)) {
            unequal = (size != 2) || (digits[0] != (uintval & (unsigned long) PyLong_MASK))
                 | (digits[1] != ((uintval >> (1 * PyLong_SHIFT)) & (unsigned long) PyLong_MASK));
        } else
#endif
            unequal = (size != 1) || (((unsigned long) digits[0]) != (uintval & (unsigned long) PyLong_MASK));
        return (unequal == 0);
    }
    #endif
    if (PyFloat_CheckExact(op1)) {
        const long b = intval;
#if CYTHON_COMPILING_IN_LIMITED_API
        double a = __pyx_PyFloat_AsDouble(op1);
#else
        double a = PyFloat_AS_DOUBLE(op1);
#endif
        return ((double)a == (double)b);
    }
    return __Pyx_PyObject_IsTrueAndDecref(
        PyObject_RichCompare(op1, op2, Py_EQ));
}

/* DictGetItem */
#if PY_MAJOR_VERSION >= 3 && !CYTHON_COMPILING_IN_PYPY
static PyObject *__Pyx_PyDict_GetItem(PyObject *d, PyObject* key) {
    PyObject *value;
    value = PyDict_GetItemWithError(d, key);
    if (unlikely(!value)) {
        if (!PyErr_Occurred()) {
            if (unlikely(PyTuple_Check(key))) {
                PyObject* args = PyTuple_Pack(1, key);
                if (likely(args)) {
                    PyErr_SetObject(PyExc_KeyError, args);
                    Py_DECREF(args);
                }
            } else {
                PyErr_SetObject(PyExc_KeyError, key);
            }
        }
        return NULL;
    }
    Py_INCREF(value);
    return value;
}
#endif

/* FixUpExtensionType */
#if CYTHON_USE_TYPE_SPECS
static int __Pyx_fix_up_extension_type_from_spec(PyType_Spec *spec, PyTypeObject *type) {
#if PY_VERSION_HEX > 0x030900B1 || CYTHON_COMPILING_IN_LIMITED_API
    CYTHON_UNUSED_VAR(spec);
    CYTHON_UNUSED_VAR(type);
#else
    const PyType_Slot *slot = spec->slots;
    while (slot && slot->slot && slot->slot != Py_tp_members)
        slot++;
    if (slot && slot->slot == Py_tp_members) {
        int changed = 0;
#if !(PY_VERSION_HEX <= 0x030900b1 && CYTHON_COMPILING_IN_CPYTHON)
        const
#endif
            PyMemberDef *memb = (PyMemberDef*) slot->pfunc;
        while (memb && memb->name) {
            if (memb->name[0] == '_' && memb->name[1] == '_') {
#if PY_VERSION_HEX < 0x030900b1
                if (strcmp(memb->name, "__weaklistoffset__") == 0) {
                    assert(memb->type == T_PYSSIZET);
                    assert(memb->flags == READONLY);
                    type->tp_weaklistoffset = memb->offset;
                    changed = 1;
                }
                else if (strcmp(memb->name, "__dictoffset__") == 0) {
                    assert(memb->type == T_PYSSIZET);
                    assert(memb->flags == READONLY);
                    type->tp_dictoffset = memb->offset;
                    changed = 1;
                }
#if CYTHON_METH_FASTCALL
                else if (strcmp(memb->name, "__vectorcalloffset__") == 0) {
                    assert(memb->type == T_PYSSIZET);
                    assert(memb->flags == READONLY);
#if PY_VERSION_HEX >= 0x030800b4
                    type->tp_vectorcall_offset = memb->offset;
#else
                    type->tp_print = (printfunc) memb->offset;
#endif
                    changed = 1;
                }
#endif
#else
                if ((0));
#endif
#if PY_VERSION_HEX <= 0x030900b1 && CYTHON_COMPILING_IN_CPYTHON
                else if (strcmp(memb->name, "__module__") == 0) {
                    PyObject *descr;
                    assert(memb->type == T_OBJECT);
                    assert(memb->flags == 0 || memb->flags == READONLY);
                    descr = PyDescr_NewMember(type, memb);
                    if (unlikely(!descr))
                        return -1;
                    if (unlikely(PyDict_SetItem(type->tp_dict, PyDescr_NAME(descr), descr) < 0)) {
                        Py_DECREF(descr);
                        return -1;
                    }
                    Py_DECREF(descr);
                    changed = 1;
                }
#endif
            }
            memb++;
        }
        if (changed)
            PyType_Modified(type);
    }
#endif
    return 0;
}
#endif

/* FetchSharedCythonModule */
static PyObject *__Pyx_FetchSharedCythonABIModule(void) {
    PyObject *abi_module = PyImport_AddModule((char*) __PYX_ABI_MODULE_NAME);
    if (unlikely(!abi_module)) return NULL;
    Py_INCREF(abi_module);
    return abi_module;
}

/* FetchCommonType */
static int __Pyx_VerifyCachedType(PyObject *cached_type,
                               const char *name,
                               Py_ssize_t basicsize,
                               Py_ssize_t expected_basicsize) {
    if (!PyType_Check(cached_type)) {
        PyErr_Format(PyExc_TypeError,
            "Shared Cython type %.200s is not a type object", name);
        return -1;
    }
    if (basicsize != expected_basicsize) {
        PyErr_Format(PyExc_TypeError,
            "Shared Cython type %.200s has the wrong size, try recompiling",
            name);
        return -1;
    }
    return 0;
}
#if !CYTHON_USE_TYPE_SPECS
static PyTypeObject* __Pyx_FetchCommonType(PyTypeObject* type) {
    PyObject* abi_module;
    const char* object_name;
    PyTypeObject *cached_type = NULL;
    abi_module = __Pyx_FetchSharedCythonABIModule();
    if (!abi_module) return NULL;
    object_name = strrchr(type->tp_name, '.');
    object_name = object_name ? object_name+1 : type->tp_name;
    cached_type = (PyTypeObject*) PyObject_GetAttrString(abi_module, object_name);
    if (cached_type) {
        if (__Pyx_VerifyCachedType(
              (PyObject *)cached_type,
              object_name,
              cached_type->tp_basicsize,
              type->tp_basicsize) < 0) {
            goto bad;
        }
        goto done;
    }
    if (!PyErr_ExceptionMatches(PyExc_AttributeError)) goto bad;
    PyErr_Clear();
    if (PyType_Ready(type) < 0) goto bad;
    if (PyObject_SetAttrString(abi_module, object_name, (PyObject *)type) < 0)
        goto bad;
    Py_INCREF(type);
    cached_type = type;
done:
    Py_DECREF(abi_module);
    return cached_type;
bad:
    Py_XDECREF(cached_type);
    cached_type = NULL;
    goto done;
}
#else
static PyTypeObject *__Pyx_FetchCommonTypeFromSpec(PyObject *module, PyType_Spec *spec, PyObject *bases) {
    PyObject *abi_module, *cached_type = NULL;
    const char* object_name = strrchr(spec->name, '.');
    object_name = object_name ? object_name+1 : spec->name;
    abi_module = __Pyx_FetchSharedCythonABIModule();
    if (!abi_module) return NULL;
    cached_type = PyObject_GetAttrString(abi_module, object_name);
    if (cached_type) {
        Py_ssize_t basicsize;
#if CYTHON_COMPILING_IN_LIMITED_API
        PyObject *py_basicsize;
        py_basicsize = PyObject_GetAttrString(cached_type, "__basicsize__");
        if (unlikely(!py_basicsize)) goto bad;
        basicsize = PyLong_AsSsize_t(py_basicsize);
        Py_DECREF(py_basicsize);
        py_basicsize = 0;
        if (unlikely(basicsize == (Py_ssize_t)-1) && PyErr_Occurred()) goto bad;
#else
        basicsize = likely(PyType_Check(cached_type)) ? ((PyTypeObject*) cached_type)->tp_basicsize : -1;
#endif
        if (__Pyx_VerifyCachedType(
              cached_type,
              object_name,
              basicsize,
              spec->basicsize) < 0) {
            goto bad;
        }
        goto done;
    }
    if (!PyErr_ExceptionMatches(PyExc_AttributeError)) goto bad;
    PyErr_Clear();
    CYTHON_UNUSED_VAR(module);
    cached_type = __Pyx_PyType_FromModuleAndSpec(abi_module, spec, bases);
    if (unlikely(!cached_type)) goto bad;
    if (unlikely(__Pyx_fix_up_extension_type_from_spec(spec, (PyTypeObject *) cached_type) < 0)) goto bad;
    if (PyObject_SetAttrString(abi_module, object_name, cached_type) < 0) goto bad;
done:
    Py_DECREF(abi_module);
    assert(cached_type == NULL || PyType_Check(cached_type));
    return (PyTypeObject *) cached_type;
bad:
    Py_XDECREF(cached_type);
    cached_type = NULL;
    goto done;
}
#endif

/* PyVectorcallFastCallDict */
#if CYTHON_METH_FASTCALL
static PyObject *__Pyx_PyVectorcall_FastCallDict_kw(PyObject *func, __pyx_vectorcallfunc vc, PyObject *const *args, size_t nargs, PyObject *kw)
{
    PyObject *res = NULL;
    PyObject *kwnames;
    PyObject **newargs;
    PyObject **kwvalues;
    Py_ssize_t i, pos;
    size_t j;
    PyObject *key, *value;
    unsigned long keys_are_strings;
    Py_ssize_t nkw = PyDict_GET_SIZE(kw);
    newargs = (PyObject **)PyMem_Malloc((nargs + (size_t)nkw) * sizeof(args[0]));
    if (unlikely(newargs == NULL)) {
        PyErr_NoMemory();
        return NULL;
    }
    for (j = 0; j < nargs; j++) newargs[j] = args[j];
    kwnames = PyTuple_New(nkw);
    if (unlikely(kwnames == NULL)) {
        PyMem_Free(newargs);
        return NULL;
    }
    kwvalues = newargs + nargs;
    pos = i = 0;
    keys_are_strings = Py_TPFLAGS_UNICODE_SUBCLASS;
    while (PyDict_Next(kw, &pos, &key, &value)) {
        keys_are_strings &= Py_TYPE(key)->tp_flags;
        Py_INCREF(key);
        Py_INCREF(value);
        PyTuple_SET_ITEM(kwnames, i, key);
        kwvalues[i] = value;
        i++;
    }
    if (unlikely(!keys_are_strings)) {
        PyErr_SetString(PyExc_TypeError, "keywords must be strings");
        goto cleanup;
    }
    res = vc(func, newargs, nargs, kwnames);
cleanup:
    Py_DECREF(kwnames);
    for (i = 0; i < nkw; i++)
        Py_DECREF(kwvalues[i]);
    PyMem_Free(newargs);
    return res;
}
static CYTHON_INLINE PyObject *__Pyx_PyVectorcall_FastCallDict(PyObject *func, __pyx_vectorcallfunc vc, PyObject *const *args, size_t nargs, PyObject *kw)
{
    if (likely(kw == NULL) || PyDict_GET_SIZE(kw) == 0) {
        return vc(func, args, nargs, NULL);
    }
    return __Pyx_PyVectorcall_FastCallDict_kw(func, vc, args, nargs, kw);
}
#endif

/* CythonFunctionShared */
static CYTHON_INLINE void __Pyx__CyFunction_SetClassObj(__pyx_CyFunctionObject* f, PyObject* classobj) {
#if PY_VERSION_HEX < 0x030900B1 || CYTHON_COMPILING_IN_LIMITED_API
    __Pyx_Py_XDECREF_SET(
        __Pyx_CyFunction_GetClassObj(f),
            ((classobj) ? __Pyx_NewRef(classobj) : NULL));
#else
    __Pyx_Py_XDECREF_SET(
        ((PyCMethodObject *) (f))->mm_class,
        (PyTypeObject*)((classobj) ? __Pyx_NewRef(classobj) : NULL));
#endif
}
static PyObject *
__Pyx_CyFunction_get_doc(__pyx_CyFunctionObject *op, void *closure)
{
    CYTHON_UNUSED_VAR(closure);
    if (unlikely(op->func_doc == NULL)) {
#if CYTHON_COMPILING_IN_LIMITED_API
        op->func_doc = PyObject_GetAttrString(op->func, "__doc__");
        if (unlikely(!op->func_doc)) return NULL;
#else
        if (((PyCFunctionObject*)op)->m_ml->ml_doc) {
#if PY_MAJOR_VERSION >= 3
            op->func_doc = PyUnicode_FromString(((PyCFunctionObject*)op)->m_ml->ml_doc);
#else
            op->func_doc = PyString_FromString(((PyCFunctionObject*)op)->m_ml->ml_doc);
#endif
            if (unlikely(op->func_doc == NULL))
                return NULL;
        } else {
            Py_INCREF(Py_None);
            return Py_None;
        }
#endif
    }
    Py_INCREF(op->func_doc);
    return op->func_doc;
}
static int
__Pyx_CyFunction_set_doc(__pyx_CyFunctionObject *op, PyObject *value, void *context)
{
    CYTHON_UNUSED_VAR(context);
    if (value == NULL) {
        value = Py_None;
    }
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->func_doc, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_name(__pyx_CyFunctionObject *op, void *context)
{
    CYTHON_UNUSED_VAR(context);
    if (unlikely(op->func_name == NULL)) {
#if CYTHON_COMPILING_IN_LIMITED_API
        op->func_name = PyObject_GetAttrString(op->func, "__name__");
#elif PY_MAJOR_VERSION >= 3
        op->func_name = PyUnicode_InternFromString(((PyCFunctionObject*)op)->m_ml->ml_name);
#else
        op->func_name = PyString_InternFromString(((PyCFunctionObject*)op)->m_ml->ml_name);
#endif
        if (unlikely(op->func_name == NULL))
            return NULL;
    }
    Py_INCREF(op->func_name);
    return op->func_name;
}
static int
__Pyx_CyFunction_set_name(__pyx_CyFunctionObject *op, PyObject *value, void *context)
{
    CYTHON_UNUSED_VAR(context);
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__name__ must be set to a string object");
        return -1;
    }
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->func_name, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_qualname(__pyx_CyFunctionObject *op, void *context)
{
    CYTHON_UNUSED_VAR(context);
    Py_INCREF(op->func_qualname);
    return op->func_qualname;
}
static int
__Pyx_CyFunction_set_qualname(__pyx_CyFunctionObject *op, PyObject *value, void *context)
{
    CYTHON_UNUSED_VAR(context);
#if PY_MAJOR_VERSION >= 3
    if (unlikely(value == NULL || !PyUnicode_Check(value)))
#else
    if (unlikely(value == NULL || !PyString_Check(value)))
#endif
    {
        PyErr_SetString(PyExc_TypeError,
                        "__qualname__ must be set to a string object");
        return -1;
    }
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->func_qualname, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_dict(__pyx_CyFunctionObject *op, void *context)
{
    CYTHON_UNUSED_VAR(context);
    if (unlikely(op->func_dict == NULL)) {
        op->func_dict = PyDict_New();
        if (unlikely(op->func_dict == NULL))
            return NULL;
    }
    Py_INCREF(op->func_dict);
    return op->func_dict;
}
static int
__Pyx_CyFunction_set_dict(__pyx_CyFunctionObject *op, PyObject *value, void *context)
{
    CYTHON_UNUSED_VAR(context);
    if (unlikely(value == NULL)) {
        PyErr_SetString(PyExc_TypeError,
               "function's dictionary may not be deleted");
        return -1;
    }
    if (unlikely(!PyDict_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
               "setting function's dictionary to a non-dict");
        return -1;
    }
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->func_dict, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_globals(__pyx_CyFunctionObject *op, void *context)
{
    CYTHON_UNUSED_VAR(context);
    Py_INCREF(op->func_globals);
    return op->func_globals;
}
static PyObject *
__Pyx_CyFunction_get_closure(__pyx_CyFunctionObject *op, void *context)
{
    CYTHON_UNUSED_VAR(op);
    CYTHON_UNUSED_VAR(context);
    Py_INCREF(Py_None);
    return Py_None;
}
static PyObject *
__Pyx_CyFunction_get_code(__pyx_CyFunctionObject *op, void *context)
{
    PyObject* result = (op->func_code) ? op->func_code : Py_None;
    CYTHON_UNUSED_VAR(context);
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_init_defaults(__pyx_CyFunctionObject *op) {
    int result = 0;
    PyObject *res = op->defaults_getter((PyObject *) op);
    if (unlikely(!res))
        return -1;
    #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
    op->defaults_tuple = PyTuple_GET_ITEM(res, 0);
    Py_INCREF(op->defaults_tuple);
    op->defaults_kwdict = PyTuple_GET_ITEM(res, 1);
    Py_INCREF(op->defaults_kwdict);
    #else
    op->defaults_tuple = __Pyx_PySequence_ITEM(res, 0);
    if (unlikely(!op->defaults_tuple)) result = -1;
    else {
        op->defaults_kwdict = __Pyx_PySequence_ITEM(res, 1);
        if (unlikely(!op->defaults_kwdict)) result = -1;
    }
    #endif
    Py_DECREF(res);
    return result;
}
static int
__Pyx_CyFunction_set_defaults(__pyx_CyFunctionObject *op, PyObject* value, void *context) {
    CYTHON_UNUSED_VAR(context);
    if (!value) {
        value = Py_None;
    } else if (unlikely(value != Py_None && !PyTuple_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
                        "__defaults__ must be set to a tuple object");
        return -1;
    }
    PyErr_WarnEx(PyExc_RuntimeWarning, "changes to cyfunction.__defaults__ will not "
                 "currently affect the values used in function calls", 1);
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->defaults_tuple, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_defaults(__pyx_CyFunctionObject *op, void *context) {
    PyObject* result = op->defaults_tuple;
    CYTHON_UNUSED_VAR(context);
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (unlikely(__Pyx_CyFunction_init_defaults(op) < 0)) return NULL;
            result = op->defaults_tuple;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_kwdefaults(__pyx_CyFunctionObject *op, PyObject* value, void *context) {
    CYTHON_UNUSED_VAR(context);
    if (!value) {
        value = Py_None;
    } else if (unlikely(value != Py_None && !PyDict_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
                        "__kwdefaults__ must be set to a dict object");
        return -1;
    }
    PyErr_WarnEx(PyExc_RuntimeWarning, "changes to cyfunction.__kwdefaults__ will not "
                 "currently affect the values used in function calls", 1);
    Py_INCREF(value);
    __Pyx_Py_XDECREF_SET(op->defaults_kwdict, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_kwdefaults(__pyx_CyFunctionObject *op, void *context) {
    PyObject* result = op->defaults_kwdict;
    CYTHON_UNUSED_VAR(context);
    if (unlikely(!result)) {
        if (op->defaults_getter) {
            if (unlikely(__Pyx_CyFunction_init_defaults(op) < 0)) return NULL;
            result = op->defaults_kwdict;
        } else {
            result = Py_None;
        }
    }
    Py_INCREF(result);
    return result;
}
static int
__Pyx_CyFunction_set_annotations(__pyx_CyFunctionObject *op, PyObject* value, void *context) {
    CYTHON_UNUSED_VAR(context);
    if (!value || value == Py_None) {
        value = NULL;
    } else if (unlikely(!PyDict_Check(value))) {
        PyErr_SetString(PyExc_TypeError,
                        "__annotations__ must be set to a dict object");
        return -1;
    }
    Py_XINCREF(value);
    __Pyx_Py_XDECREF_SET(op->func_annotations, value);
    return 0;
}
static PyObject *
__Pyx_CyFunction_get_annotations(__pyx_CyFunctionObject *op, void *context) {
    PyObject* result = op->func_annotations;
    CYTHON_UNUSED_VAR(context);
    if (unlikely(!result)) {
        result = PyDict_New();
        if (unlikely(!result)) return NULL;
        op->func_annotations = result;
    }
    Py_INCREF(result);
    return result;
}
static PyObject *
__Pyx_CyFunction_get_is_coroutine(__pyx_CyFunctionObject *op, void *context) {
    int is_coroutine;
    CYTHON_UNUSED_VAR(context);
    if (op->func_is_coroutine) {
        return __Pyx_NewRef(op->func_is_coroutine);
    }
    is_coroutine = op->flags & __Pyx_CYFUNCTION_COROUTINE;
#if PY_VERSION_HEX >= 0x03050000
    if (is_coroutine) {
        PyObject *module, *fromlist, *marker = __pyx_n_s_is_coroutine;
        fromlist = PyList_New(1);
        if (unlikely(!fromlist)) return NULL;
        Py_INCREF(marker);
#if CYTHON_ASSUME_SAFE_MACROS
        PyList_SET_ITEM(fromlist, 0, marker);
#else
        if (unlikely(PyList_SetItem(fromlist, 0, marker) < 0)) {
            Py_DECREF(marker);
            Py_DECREF(fromlist);
            return NULL;
        }
#endif
        module = PyImport_ImportModuleLevelObject(__pyx_n_s_asyncio_coroutines, NULL, NULL, fromlist, 0);
        Py_DECREF(fromlist);
        if (unlikely(!module)) goto ignore;
        op->func_is_coroutine = __Pyx_PyObject_GetAttrStr(module, marker);
        Py_DECREF(module);
        if (likely(op->func_is_coroutine)) {
            return __Pyx_NewRef(op->func_is_coroutine);
        }
ignore:
        PyErr_Clear();
    }
#endif
    op->func_is_coroutine = __Pyx_PyBool_FromLong(is_coroutine);
    return __Pyx_NewRef(op->func_is_coroutine);
}
#if CYTHON_COMPILING_IN_LIMITED_API
static PyObject *
__Pyx_CyFunction_get_module(__pyx_CyFunctionObject *op, void *context) {
    CYTHON_UNUSED_VAR(context);
    return PyObject_GetAttrString(op->func, "__module__");
}
static int
__Pyx_CyFunction_set_module(__pyx_CyFunctionObject *op, PyObject* value, void *context) {
    CYTHON_UNUSED_VAR(context);
    return PyObject_SetAttrString(op->func, "__module__", value);
}
#endif
static PyGetSetDef __pyx_CyFunction_getsets[] = {
    {(char *) "func_doc", (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "__doc__",  (getter)__Pyx_CyFunction_get_doc, (setter)__Pyx_CyFunction_set_doc, 0, 0},
    {(char *) "func_name", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__name__", (getter)__Pyx_CyFunction_get_name, (setter)__Pyx_CyFunction_set_name, 0, 0},
    {(char *) "__qualname__", (getter)__Pyx_CyFunction_get_qualname, (setter)__Pyx_CyFunction_set_qualname, 0, 0},
    {(char *) "func_dict", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "__dict__", (getter)__Pyx_CyFunction_get_dict, (setter)__Pyx_CyFunction_set_dict, 0, 0},
    {(char *) "func_globals", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "__globals__", (getter)__Pyx_CyFunction_get_globals, 0, 0, 0},
    {(char *) "func_closure", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "__closure__", (getter)__Pyx_CyFunction_get_closure, 0, 0, 0},
    {(char *) "func_code", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "__code__", (getter)__Pyx_CyFunction_get_code, 0, 0, 0},
    {(char *) "func_defaults", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__defaults__", (getter)__Pyx_CyFunction_get_defaults, (setter)__Pyx_CyFunction_set_defaults, 0, 0},
    {(char *) "__kwdefaults__", (getter)__Pyx_CyFunction_get_kwdefaults, (setter)__Pyx_CyFunction_set_kwdefaults, 0, 0},
    {(char *) "__annotations__", (getter)__Pyx_CyFunction_get_annotations, (setter)__Pyx_CyFunction_set_annotations, 0, 0},
    {(char *) "_is_coroutine", (getter)__Pyx_CyFunction_get_is_coroutine, 0, 0, 0},
#if CYTHON_COMPILING_IN_LIMITED_API
    {"__module__", (getter)__Pyx_CyFunction_get_module, (setter)__Pyx_CyFunction_set_module, 0, 0},
#endif
    {0, 0, 0, 0, 0}
};
static PyMemberDef __pyx_CyFunction_members[] = {
#if !CYTHON_COMPILING_IN_LIMITED_API
    {(char *) "__module__", T_OBJECT, offsetof(PyCFunctionObject, m_module), 0, 0},
#endif
#if CYTHON_USE_TYPE_SPECS
    {(char *) "__dictoffset__", T_PYSSIZET, offsetof(__pyx_CyFunctionObject, func_dict), READONLY, 0},
#if CYTHON_METH_FASTCALL
#if CYTHON_BACKPORT_VECTORCALL
    {(char *) "__vectorcalloffset__", T_PYSSIZET, offsetof(__pyx_CyFunctionObject, func_vectorcall), READONLY, 0},
#else
#if !CYTHON_COMPILING_IN_LIMITED_API
    {(char *) "__vectorcalloffset__", T_PYSSIZET, offsetof(PyCFunctionObject, vectorcall), READONLY, 0},
#endif
#endif
#endif
#if PY_VERSION_HEX < 0x030500A0 || CYTHON_COMPILING_IN_LIMITED_API
    {(char *) "__weaklistoffset__", T_PYSSIZET, offsetof(__pyx_CyFunctionObject, func_weakreflist), READONLY, 0},
#else
    {(char *) "__weaklistoffset__", T_PYSSIZET, offsetof(PyCFunctionObject, m_weakreflist), READONLY, 0},
#endif
#endif
    {0, 0, 0,  0, 0}
};
static PyObject *
__Pyx_CyFunction_reduce(__pyx_CyFunctionObject *m, PyObject *args)
{
    CYTHON_UNUSED_VAR(args);
#if PY_MAJOR_VERSION >= 3
    Py_INCREF(m->func_qualname);
    return m->func_qualname;
#else
    return PyString_FromString(((PyCFunctionObject*)m)->m_ml->ml_name);
#endif
}
static PyMethodDef __pyx_CyFunction_methods[] = {
    {"__reduce__", (PyCFunction)__Pyx_CyFunction_reduce, METH_VARARGS, 0},
    {0, 0, 0, 0}
};
#if PY_VERSION_HEX < 0x030500A0 || CYTHON_COMPILING_IN_LIMITED_API
#define __Pyx_CyFunction_weakreflist(cyfunc) ((cyfunc)->func_weakreflist)
#else
#define __Pyx_CyFunction_weakreflist(cyfunc) (((PyCFunctionObject*)cyfunc)->m_weakreflist)
#endif
static PyObject *__Pyx_CyFunction_Init(__pyx_CyFunctionObject *op, PyMethodDef *ml, int flags, PyObject* qualname,
                                       PyObject *closure, PyObject *module, PyObject* globals, PyObject* code) {
#if !CYTHON_COMPILING_IN_LIMITED_API
    PyCFunctionObject *cf = (PyCFunctionObject*) op;
#endif
    if (unlikely(op == NULL))
        return NULL;
#if CYTHON_COMPILING_IN_LIMITED_API
    op->func = PyCFunction_NewEx(ml, (PyObject*)op, module);
    if (unlikely(!op->func)) return NULL;
#endif
    op->flags = flags;
    __Pyx_CyFunction_weakreflist(op) = NULL;
#if !CYTHON_COMPILING_IN_LIMITED_API
    cf->m_ml = ml;
    cf->m_self = (PyObject *) op;
#endif
    Py_XINCREF(closure);
    op->func_closure = closure;
#if !CYTHON_COMPILING_IN_LIMITED_API
    Py_XINCREF(module);
    cf->m_module = module;
#endif
    op->func_dict = NULL;
    op->func_name = NULL;
    Py_INCREF(qualname);
    op->func_qualname = qualname;
    op->func_doc = NULL;
#if PY_VERSION_HEX < 0x030900B1 || CYTHON_COMPILING_IN_LIMITED_API
    op->func_classobj = NULL;
#else
    ((PyCMethodObject*)op)->mm_class = NULL;
#endif
    op->func_globals = globals;
    Py_INCREF(op->func_globals);
    Py_XINCREF(code);
    op->func_code = code;
    op->defaults_pyobjects = 0;
    op->defaults_size = 0;
    op->defaults = NULL;
    op->defaults_tuple = NULL;
    op->defaults_kwdict = NULL;
    op->defaults_getter = NULL;
    op->func_annotations = NULL;
    op->func_is_coroutine = NULL;
#if CYTHON_METH_FASTCALL
    switch (ml->ml_flags & (METH_VARARGS | METH_FASTCALL | METH_NOARGS | METH_O | METH_KEYWORDS | METH_METHOD)) {
    case METH_NOARGS:
        __Pyx_CyFunction_func_vectorcall(op) = __Pyx_CyFunction_Vectorcall_NOARGS;
        break;
    case METH_O:
        __Pyx_CyFunction_func_vectorcall(op) = __Pyx_CyFunction_Vectorcall_O;
        break;
    case METH_METHOD | METH_FASTCALL | METH_KEYWORDS:
        __Pyx_CyFunction_func_vectorcall(op) = __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS_METHOD;
        break;
    case METH_FASTCALL | METH_KEYWORDS:
        __Pyx_CyFunction_func_vectorcall(op) = __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS;
        break;
    case METH_VARARGS | METH_KEYWORDS:
        __Pyx_CyFunction_func_vectorcall(op) = NULL;
        break;
    default:
        PyErr_SetString(PyExc_SystemError, "Bad call flags for CyFunction");
        Py_DECREF(op);
        return NULL;
    }
#endif
    return (PyObject *) op;
}
static int
__Pyx_CyFunction_clear(__pyx_CyFunctionObject *m)
{
    Py_CLEAR(m->func_closure);
#if CYTHON_COMPILING_IN_LIMITED_API
    Py_CLEAR(m->func);
#else
    Py_CLEAR(((PyCFunctionObject*)m)->m_module);
#endif
    Py_CLEAR(m->func_dict);
    Py_CLEAR(m->func_name);
    Py_CLEAR(m->func_qualname);
    Py_CLEAR(m->func_doc);
    Py_CLEAR(m->func_globals);
    Py_CLEAR(m->func_code);
#if !CYTHON_COMPILING_IN_LIMITED_API
#if PY_VERSION_HEX < 0x030900B1
    Py_CLEAR(__Pyx_CyFunction_GetClassObj(m));
#else
    {
        PyObject *cls = (PyObject*) ((PyCMethodObject *) (m))->mm_class;
        ((PyCMethodObject *) (m))->mm_class = NULL;
        Py_XDECREF(cls);
    }
#endif
#endif
    Py_CLEAR(m->defaults_tuple);
    Py_CLEAR(m->defaults_kwdict);
    Py_CLEAR(m->func_annotations);
    Py_CLEAR(m->func_is_coroutine);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_XDECREF(pydefaults[i]);
        PyObject_Free(m->defaults);
        m->defaults = NULL;
    }
    return 0;
}
static void __Pyx__CyFunction_dealloc(__pyx_CyFunctionObject *m)
{
    if (__Pyx_CyFunction_weakreflist(m) != NULL)
        PyObject_ClearWeakRefs((PyObject *) m);
    __Pyx_CyFunction_clear(m);
    __Pyx_PyHeapTypeObject_GC_Del(m);
}
static void __Pyx_CyFunction_dealloc(__pyx_CyFunctionObject *m)
{
    PyObject_GC_UnTrack(m);
    __Pyx__CyFunction_dealloc(m);
}
static int __Pyx_CyFunction_traverse(__pyx_CyFunctionObject *m, visitproc visit, void *arg)
{
    Py_VISIT(m->func_closure);
#if CYTHON_COMPILING_IN_LIMITED_API
    Py_VISIT(m->func);
#else
    Py_VISIT(((PyCFunctionObject*)m)->m_module);
#endif
    Py_VISIT(m->func_dict);
    Py_VISIT(m->func_name);
    Py_VISIT(m->func_qualname);
    Py_VISIT(m->func_doc);
    Py_VISIT(m->func_globals);
    Py_VISIT(m->func_code);
#if !CYTHON_COMPILING_IN_LIMITED_API
    Py_VISIT(__Pyx_CyFunction_GetClassObj(m));
#endif
    Py_VISIT(m->defaults_tuple);
    Py_VISIT(m->defaults_kwdict);
    Py_VISIT(m->func_is_coroutine);
    if (m->defaults) {
        PyObject **pydefaults = __Pyx_CyFunction_Defaults(PyObject *, m);
        int i;
        for (i = 0; i < m->defaults_pyobjects; i++)
            Py_VISIT(pydefaults[i]);
    }
    return 0;
}
static PyObject*
__Pyx_CyFunction_repr(__pyx_CyFunctionObject *op)
{
#if PY_MAJOR_VERSION >= 3
    return PyUnicode_FromFormat("<cyfunction %U at %p>",
                                op->func_qualname, (void *)op);
#else
    return PyString_FromFormat("<cyfunction %s at %p>",
                               PyString_AsString(op->func_qualname), (void *)op);
#endif
}
static PyObject * __Pyx_CyFunction_CallMethod(PyObject *func, PyObject *self, PyObject *arg, PyObject *kw) {
#if CYTHON_COMPILING_IN_LIMITED_API
    PyObject *f = ((__pyx_CyFunctionObject*)func)->func;
    PyObject *py_name = NULL;
    PyCFunction meth;
    int flags;
    meth = PyCFunction_GetFunction(f);
    if (unlikely(!meth)) return NULL;
    flags = PyCFunction_GetFlags(f);
    if (unlikely(flags < 0)) return NULL;
#else
    PyCFunctionObject* f = (PyCFunctionObject*)func;
    PyCFunction meth = f->m_ml->ml_meth;
    int flags = f->m_ml->ml_flags;
#endif
    Py_ssize_t size;
    switch (flags & (METH_VARARGS | METH_KEYWORDS | METH_NOARGS | METH_O)) {
    case METH_VARARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0))
            return (*meth)(self, arg);
        break;
    case METH_VARARGS | METH_KEYWORDS:
        return (*(PyCFunctionWithKeywords)(void*)meth)(self, arg, kw);
    case METH_NOARGS:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
#if CYTHON_ASSUME_SAFE_MACROS
            size = PyTuple_GET_SIZE(arg);
#else
            size = PyTuple_Size(arg);
            if (unlikely(size < 0)) return NULL;
#endif
            if (likely(size == 0))
                return (*meth)(self, NULL);
#if CYTHON_COMPILING_IN_LIMITED_API
            py_name = __Pyx_CyFunction_get_name((__pyx_CyFunctionObject*)func, NULL);
            if (!py_name) return NULL;
            PyErr_Format(PyExc_TypeError,
                "%.200S() takes no arguments (%" CYTHON_FORMAT_SSIZE_T "d given)",
                py_name, size);
            Py_DECREF(py_name);
#else
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes no arguments (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
#endif
            return NULL;
        }
        break;
    case METH_O:
        if (likely(kw == NULL || PyDict_Size(kw) == 0)) {
#if CYTHON_ASSUME_SAFE_MACROS
            size = PyTuple_GET_SIZE(arg);
#else
            size = PyTuple_Size(arg);
            if (unlikely(size < 0)) return NULL;
#endif
            if (likely(size == 1)) {
                PyObject *result, *arg0;
                #if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
                arg0 = PyTuple_GET_ITEM(arg, 0);
                #else
                arg0 = __Pyx_PySequence_ITEM(arg, 0); if (unlikely(!arg0)) return NULL;
                #endif
                result = (*meth)(self, arg0);
                #if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
                Py_DECREF(arg0);
                #endif
                return result;
            }
#if CYTHON_COMPILING_IN_LIMITED_API
            py_name = __Pyx_CyFunction_get_name((__pyx_CyFunctionObject*)func, NULL);
            if (!py_name) return NULL;
            PyErr_Format(PyExc_TypeError,
                "%.200S() takes exactly one argument (%" CYTHON_FORMAT_SSIZE_T "d given)",
                py_name, size);
            Py_DECREF(py_name);
#else
            PyErr_Format(PyExc_TypeError,
                "%.200s() takes exactly one argument (%" CYTHON_FORMAT_SSIZE_T "d given)",
                f->m_ml->ml_name, size);
#endif
            return NULL;
        }
        break;
    default:
        PyErr_SetString(PyExc_SystemError, "Bad call flags for CyFunction");
        return NULL;
    }
#if CYTHON_COMPILING_IN_LIMITED_API
    py_name = __Pyx_CyFunction_get_name((__pyx_CyFunctionObject*)func, NULL);
    if (!py_name) return NULL;
    PyErr_Format(PyExc_TypeError, "%.200S() takes no keyword arguments",
                 py_name);
    Py_DECREF(py_name);
#else
    PyErr_Format(PyExc_TypeError, "%.200s() takes no keyword arguments",
                 f->m_ml->ml_name);
#endif
    return NULL;
}
static CYTHON_INLINE PyObject *__Pyx_CyFunction_Call(PyObject *func, PyObject *arg, PyObject *kw) {
    PyObject *self, *result;
#if CYTHON_COMPILING_IN_LIMITED_API
    self = PyCFunction_GetSelf(((__pyx_CyFunctionObject*)func)->func);
    if (unlikely(!self) && PyErr_Occurred()) return NULL;
#else
    self = ((PyCFunctionObject*)func)->m_self;
#endif
    result = __Pyx_CyFunction_CallMethod(func, self, arg, kw);
    return result;
}
static PyObject *__Pyx_CyFunction_CallAsMethod(PyObject *func, PyObject *args, PyObject *kw) {
    PyObject *result;
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *) func;
#if CYTHON_METH_FASTCALL
     __pyx_vectorcallfunc vc = __Pyx_CyFunction_func_vectorcall(cyfunc);
    if (vc) {
#if CYTHON_ASSUME_SAFE_MACROS
        return __Pyx_PyVectorcall_FastCallDict(func, vc, &PyTuple_GET_ITEM(args, 0), (size_t)PyTuple_GET_SIZE(args), kw);
#else
        (void) &__Pyx_PyVectorcall_FastCallDict;
        return PyVectorcall_Call(func, args, kw);
#endif
    }
#endif
    if ((cyfunc->flags & __Pyx_CYFUNCTION_CCLASS) && !(cyfunc->flags & __Pyx_CYFUNCTION_STATICMETHOD)) {
        Py_ssize_t argc;
        PyObject *new_args;
        PyObject *self;
#if CYTHON_ASSUME_SAFE_MACROS
        argc = PyTuple_GET_SIZE(args);
#else
        argc = PyTuple_Size(args);
        if (unlikely(!argc) < 0) return NULL;
#endif
        new_args = PyTuple_GetSlice(args, 1, argc);
        if (unlikely(!new_args))
            return NULL;
        self = PyTuple_GetItem(args, 0);
        if (unlikely(!self)) {
            Py_DECREF(new_args);
#if PY_MAJOR_VERSION > 2
            PyErr_Format(PyExc_TypeError,
                         "unbound method %.200S() needs an argument",
                         cyfunc->func_qualname);
#else
            PyErr_SetString(PyExc_TypeError,
                            "unbound method needs an argument");
#endif
            return NULL;
        }
        result = __Pyx_CyFunction_CallMethod(func, self, new_args, kw);
        Py_DECREF(new_args);
    } else {
        result = __Pyx_CyFunction_Call(func, args, kw);
    }
    return result;
}
#if CYTHON_METH_FASTCALL
static CYTHON_INLINE int __Pyx_CyFunction_Vectorcall_CheckArgs(__pyx_CyFunctionObject *cyfunc, Py_ssize_t nargs, PyObject *kwnames)
{
    int ret = 0;
    if ((cyfunc->flags & __Pyx_CYFUNCTION_CCLASS) && !(cyfunc->flags & __Pyx_CYFUNCTION_STATICMETHOD)) {
        if (unlikely(nargs < 1)) {
            PyErr_Format(PyExc_TypeError, "%.200s() needs an argument",
                         ((PyCFunctionObject*)cyfunc)->m_ml->ml_name);
            return -1;
        }
        ret = 1;
    }
    if (unlikely(kwnames) && unlikely(PyTuple_GET_SIZE(kwnames))) {
        PyErr_Format(PyExc_TypeError,
                     "%.200s() takes no keyword arguments", ((PyCFunctionObject*)cyfunc)->m_ml->ml_name);
        return -1;
    }
    return ret;
}
static PyObject * __Pyx_CyFunction_Vectorcall_NOARGS(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames)
{
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *)func;
    PyMethodDef* def = ((PyCFunctionObject*)cyfunc)->m_ml;
#if CYTHON_BACKPORT_VECTORCALL
    Py_ssize_t nargs = (Py_ssize_t)nargsf;
#else
    Py_ssize_t nargs = PyVectorcall_NARGS(nargsf);
#endif
    PyObject *self;
    switch (__Pyx_CyFunction_Vectorcall_CheckArgs(cyfunc, nargs, kwnames)) {
    case 1:
        self = args[0];
        args += 1;
        nargs -= 1;
        break;
    case 0:
        self = ((PyCFunctionObject*)cyfunc)->m_self;
        break;
    default:
        return NULL;
    }
    if (unlikely(nargs != 0)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s() takes no arguments (%" CYTHON_FORMAT_SSIZE_T "d given)",
            def->ml_name, nargs);
        return NULL;
    }
    return def->ml_meth(self, NULL);
}
static PyObject * __Pyx_CyFunction_Vectorcall_O(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames)
{
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *)func;
    PyMethodDef* def = ((PyCFunctionObject*)cyfunc)->m_ml;
#if CYTHON_BACKPORT_VECTORCALL
    Py_ssize_t nargs = (Py_ssize_t)nargsf;
#else
    Py_ssize_t nargs = PyVectorcall_NARGS(nargsf);
#endif
    PyObject *self;
    switch (__Pyx_CyFunction_Vectorcall_CheckArgs(cyfunc, nargs, kwnames)) {
    case 1:
        self = args[0];
        args += 1;
        nargs -= 1;
        break;
    case 0:
        self = ((PyCFunctionObject*)cyfunc)->m_self;
        break;
    default:
        return NULL;
    }
    if (unlikely(nargs != 1)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s() takes exactly one argument (%" CYTHON_FORMAT_SSIZE_T "d given)",
            def->ml_name, nargs);
        return NULL;
    }
    return def->ml_meth(self, args[0]);
}
static PyObject * __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames)
{
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *)func;
    PyMethodDef* def = ((PyCFunctionObject*)cyfunc)->m_ml;
#if CYTHON_BACKPORT_VECTORCALL
    Py_ssize_t nargs = (Py_ssize_t)nargsf;
#else
    Py_ssize_t nargs = PyVectorcall_NARGS(nargsf);
#endif
    PyObject *self;
    switch (__Pyx_CyFunction_Vectorcall_CheckArgs(cyfunc, nargs, NULL)) {
    case 1:
        self = args[0];
        args += 1;
        nargs -= 1;
        break;
    case 0:
        self = ((PyCFunctionObject*)cyfunc)->m_self;
        break;
    default:
        return NULL;
    }
    return ((_PyCFunctionFastWithKeywords)(void(*)(void))def->ml_meth)(self, args, nargs, kwnames);
}
static PyObject * __Pyx_CyFunction_Vectorcall_FASTCALL_KEYWORDS_METHOD(PyObject *func, PyObject *const *args, size_t nargsf, PyObject *kwnames)
{
    __pyx_CyFunctionObject *cyfunc = (__pyx_CyFunctionObject *)func;
    PyMethodDef* def = ((PyCFunctionObject*)cyfunc)->m_ml;
    PyTypeObject *cls = (PyTypeObject *) __Pyx_CyFunction_GetClassObj(cyfunc);
#if CYTHON_BACKPORT_VECTORCALL
    Py_ssize_t nargs = (Py_ssize_t)nargsf;
#else
    Py_ssize_t nargs = PyVectorcall_NARGS(nargsf);
#endif
    PyObject *self;
    switch (__Pyx_CyFunction_Vectorcall_CheckArgs(cyfunc, nargs, NULL)) {
    case 1:
        self = args[0];
        args += 1;
        nargs -= 1;
        break;
    case 0:
        self = ((PyCFunctionObject*)cyfunc)->m_self;
        break;
    default:
        return NULL;
    }
    return ((__Pyx_PyCMethod)(void(*)(void))def->ml_meth)(self, cls, args, (size_t)nargs, kwnames);
}
#endif
#if CYTHON_USE_TYPE_SPECS
static PyType_Slot __pyx_CyFunctionType_slots[] = {
    {Py_tp_dealloc, (void *)__Pyx_CyFunction_dealloc},
    {Py_tp_repr, (void *)__Pyx_CyFunction_repr},
    {Py_tp_call, (void *)__Pyx_CyFunction_CallAsMethod},
    {Py_tp_traverse, (void *)__Pyx_CyFunction_traverse},
    {Py_tp_clear, (void *)__Pyx_CyFunction_clear},
    {Py_tp_methods, (void *)__pyx_CyFunction_methods},
    {Py_tp_members, (void *)__pyx_CyFunction_members},
    {Py_tp_getset, (void *)__pyx_CyFunction_getsets},
    {Py_tp_descr_get, (void *)__Pyx_PyMethod_New},
    {0, 0},
};
static PyType_Spec __pyx_CyFunctionType_spec = {
    __PYX_TYPE_MODULE_PREFIX "cython_function_or_method",
    sizeof(__pyx_CyFunctionObject),
    0,
#ifdef Py_TPFLAGS_METHOD_DESCRIPTOR
    Py_TPFLAGS_METHOD_DESCRIPTOR |
#endif
#if (defined(_Py_TPFLAGS_HAVE_VECTORCALL) && CYTHON_METH_FASTCALL)
    _Py_TPFLAGS_HAVE_VECTORCALL |
#endif
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC | Py_TPFLAGS_BASETYPE,
    __pyx_CyFunctionType_slots
};
#else
static PyTypeObject __pyx_CyFunctionType_type = {
    PyVarObject_HEAD_INIT(0, 0)
    __PYX_TYPE_MODULE_PREFIX "cython_function_or_method",
    sizeof(__pyx_CyFunctionObject),
    0,
    (destructor) __Pyx_CyFunction_dealloc,
#if !CYTHON_METH_FASTCALL
    0,
#elif CYTHON_BACKPORT_VECTORCALL
    (printfunc)offsetof(__pyx_CyFunctionObject, func_vectorcall),
#else
    offsetof(PyCFunctionObject, vectorcall),
#endif
    0,
    0,
#if PY_MAJOR_VERSION < 3
    0,
#else
    0,
#endif
    (reprfunc) __Pyx_CyFunction_repr,
    0,
    0,
    0,
    0,
    __Pyx_CyFunction_CallAsMethod,
    0,
    0,
    0,
    0,
#ifdef Py_TPFLAGS_METHOD_DESCRIPTOR
    Py_TPFLAGS_METHOD_DESCRIPTOR |
#endif
#if defined(_Py_TPFLAGS_HAVE_VECTORCALL) && CYTHON_METH_FASTCALL
    _Py_TPFLAGS_HAVE_VECTORCALL |
#endif
    Py_TPFLAGS_DEFAULT | Py_TPFLAGS_HAVE_GC | Py_TPFLAGS_BASETYPE,
    0,
    (traverseproc) __Pyx_CyFunction_traverse,
    (inquiry) __Pyx_CyFunction_clear,
    0,
#if PY_VERSION_HEX < 0x030500A0
    offsetof(__pyx_CyFunctionObject, func_weakreflist),
#else
    offsetof(PyCFunctionObject, m_weakreflist),
#endif
    0,
    0,
    __pyx_CyFunction_methods,
    __pyx_CyFunction_members,
    __pyx_CyFunction_getsets,
    0,
    0,
    __Pyx_PyMethod_New,
    0,
    offsetof(__pyx_CyFunctionObject, func_dict),
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
    0,
#if PY_VERSION_HEX >= 0x030400a1
    0,
#endif
#if PY_VERSION_HEX >= 0x030800b1 && (!CYTHON_COMPILING_IN_PYPY || PYPY_VERSION_NUM >= 0x07030800)
    0,
#endif
#if __PYX_NEED_TP_PRINT_SLOT
    0,
#endif
#if PY_VERSION_HEX >= 0x030C0000
    0,
#endif
#if CYTHON_COMPILING_IN_PYPY && PY_VERSION_HEX >= 0x03090000 && PY_VERSION_HEX < 0x030a0000
    0,
#endif
};
#endif
static int __pyx_CyFunction_init(PyObject *module) {
#if CYTHON_USE_TYPE_SPECS
    __pyx_CyFunctionType = __Pyx_FetchCommonTypeFromSpec(module, &__pyx_CyFunctionType_spec, NULL);
#else
    CYTHON_UNUSED_VAR(module);
    __pyx_CyFunctionType = __Pyx_FetchCommonType(&__pyx_CyFunctionType_type);
#endif
    if (unlikely(__pyx_CyFunctionType == NULL)) {
        return -1;
    }
    return 0;
}
static CYTHON_INLINE void *__Pyx_CyFunction_InitDefaults(PyObject *func, size_t size, int pyobjects) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults = PyObject_Malloc(size);
    if (unlikely(!m->defaults))
        return PyErr_NoMemory();
    memset(m->defaults, 0, size);
    m->defaults_pyobjects = pyobjects;
    m->defaults_size = size;
    return m->defaults;
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsTuple(PyObject *func, PyObject *tuple) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_tuple = tuple;
    Py_INCREF(tuple);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetDefaultsKwDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->defaults_kwdict = dict;
    Py_INCREF(dict);
}
static CYTHON_INLINE void __Pyx_CyFunction_SetAnnotationsDict(PyObject *func, PyObject *dict) {
    __pyx_CyFunctionObject *m = (__pyx_CyFunctionObject *) func;
    m->func_annotations = dict;
    Py_INCREF(dict);
}

/* CythonFunction */
static PyObject *__Pyx_CyFunction_New(PyMethodDef *ml, int flags, PyObject* qualname,
                                      PyObject *closure, PyObject *module, PyObject* globals, PyObject* code) {
    PyObject *op = __Pyx_CyFunction_Init(
        PyObject_GC_New(__pyx_CyFunctionObject, __pyx_CyFunctionType),
        ml, flags, qualname, closure, module, globals, code
    );
    if (likely(op)) {
        PyObject_GC_Track(op);
    }
    return op;
}

/* RaiseUnboundLocalError */
static CYTHON_INLINE void __Pyx_RaiseUnboundLocalError(const char *varname) {
    PyErr_Format(PyExc_UnboundLocalError, "local variable '%s' referenced before assignment", varname);
}

/* TypeImport */
#ifndef __PYX_HAVE_RT_ImportType_3_0_2
#define __PYX_HAVE_RT_ImportType_3_0_2
static PyTypeObject *__Pyx_ImportType_3_0_2(PyObject *module, const char *module_name, const char *class_name,
    size_t size, size_t alignment, enum __Pyx_ImportType_CheckSize_3_0_2 check_size)
{
    PyObject *result = 0;
    char warning[200];
    Py_ssize_t basicsize;
    Py_ssize_t itemsize;
#if CYTHON_COMPILING_IN_LIMITED_API
    PyObject *py_basicsize;
    PyObject *py_itemsize;
#endif
    result = PyObject_GetAttrString(module, class_name);
    if (!result)
        goto bad;
    if (!PyType_Check(result)) {
        PyErr_Format(PyExc_TypeError,
            "%.200s.%.200s is not a type object",
            module_name, class_name);
        goto bad;
    }
#if !CYTHON_COMPILING_IN_LIMITED_API
    basicsize = ((PyTypeObject *)result)->tp_basicsize;
    itemsize = ((PyTypeObject *)result)->tp_itemsize;
#else
    py_basicsize = PyObject_GetAttrString(result, "__basicsize__");
    if (!py_basicsize)
        goto bad;
    basicsize = PyLong_AsSsize_t(py_basicsize);
    Py_DECREF(py_basicsize);
    py_basicsize = 0;
    if (basicsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
    py_itemsize = PyObject_GetAttrString(result, "__itemsize__");
    if (!py_itemsize)
        goto bad;
    itemsize = PyLong_AsSsize_t(py_itemsize);
    Py_DECREF(py_itemsize);
    py_itemsize = 0;
    if (itemsize == (Py_ssize_t)-1 && PyErr_Occurred())
        goto bad;
#endif
    if (itemsize) {
        if (size % alignment) {
            alignment = size % alignment;
        }
        if (itemsize < (Py_ssize_t)alignment)
            itemsize = (Py_ssize_t)alignment;
    }
    if ((size_t)(basicsize + itemsize) < size) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize+itemsize);
        goto bad;
    }
    if (check_size == __Pyx_ImportType_CheckSize_Error_3_0_2 &&
            ((size_t)basicsize > size || (size_t)(basicsize + itemsize) < size)) {
        PyErr_Format(PyExc_ValueError,
            "%.200s.%.200s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd-%zd from PyObject",
            module_name, class_name, size, basicsize, basicsize+itemsize);
        goto bad;
    }
    else if (check_size == __Pyx_ImportType_CheckSize_Warn_3_0_2 && (size_t)basicsize > size) {
        PyOS_snprintf(warning, sizeof(warning),
            "%s.%s size changed, may indicate binary incompatibility. "
            "Expected %zd from C header, got %zd from PyObject",
            module_name, class_name, size, basicsize);
        if (PyErr_WarnEx(NULL, warning, 0) < 0) goto bad;
    }
    return (PyTypeObject *)result;
bad:
    Py_XDECREF(result);
    return NULL;
}
#endif

/* Import */
static PyObject *__Pyx_Import(PyObject *name, PyObject *from_list, int level) {
    PyObject *module = 0;
    PyObject *empty_dict = 0;
    PyObject *empty_list = 0;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_import;
    py_import = __Pyx_PyObject_GetAttrStr(__pyx_b, __pyx_n_s_import);
    if (unlikely(!py_import))
        goto bad;
    if (!from_list) {
        empty_list = PyList_New(0);
        if (unlikely(!empty_list))
            goto bad;
        from_list = empty_list;
    }
    #endif
    empty_dict = PyDict_New();
    if (unlikely(!empty_dict))
        goto bad;
    {
        #if PY_MAJOR_VERSION >= 3
        if (level == -1) {
            if ((1) && (strchr(__Pyx_MODULE_NAME, '.'))) {
                module = PyImport_ImportModuleLevelObject(
                    name, __pyx_d, empty_dict, from_list, 1);
                if (unlikely(!module)) {
                    if (unlikely(!PyErr_ExceptionMatches(PyExc_ImportError)))
                        goto bad;
                    PyErr_Clear();
                }
            }
            level = 0;
        }
        #endif
        if (!module) {
            #if PY_MAJOR_VERSION < 3
            PyObject *py_level = PyInt_FromLong(level);
            if (unlikely(!py_level))
                goto bad;
            module = PyObject_CallFunctionObjArgs(py_import,
                name, __pyx_d, empty_dict, from_list, py_level, (PyObject *)NULL);
            Py_DECREF(py_level);
            #else
            module = PyImport_ImportModuleLevelObject(
                name, __pyx_d, empty_dict, from_list, level);
            #endif
        }
    }
bad:
    Py_XDECREF(empty_dict);
    Py_XDECREF(empty_list);
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_import);
    #endif
    return module;
}

/* ImportDottedModule */
#if PY_MAJOR_VERSION >= 3
static PyObject *__Pyx__ImportDottedModule_Error(PyObject *name, PyObject *parts_tuple, Py_ssize_t count) {
    PyObject *partial_name = NULL, *slice = NULL, *sep = NULL;
    if (unlikely(PyErr_Occurred())) {
        PyErr_Clear();
    }
    if (likely(PyTuple_GET_SIZE(parts_tuple) == count)) {
        partial_name = name;
    } else {
        slice = PySequence_GetSlice(parts_tuple, 0, count);
        if (unlikely(!slice))
            goto bad;
        sep = PyUnicode_FromStringAndSize(".", 1);
        if (unlikely(!sep))
            goto bad;
        partial_name = PyUnicode_Join(sep, slice);
    }
    PyErr_Format(
#if PY_MAJOR_VERSION < 3
        PyExc_ImportError,
        "No module named '%s'", PyString_AS_STRING(partial_name));
#else
#if PY_VERSION_HEX >= 0x030600B1
        PyExc_ModuleNotFoundError,
#else
        PyExc_ImportError,
#endif
        "No module named '%U'", partial_name);
#endif
bad:
    Py_XDECREF(sep);
    Py_XDECREF(slice);
    Py_XDECREF(partial_name);
    return NULL;
}
#endif
#if PY_MAJOR_VERSION >= 3
static PyObject *__Pyx__ImportDottedModule_Lookup(PyObject *name) {
    PyObject *imported_module;
#if PY_VERSION_HEX < 0x030700A1 || (CYTHON_COMPILING_IN_PYPY && PYPY_VERSION_NUM  < 0x07030400)
    PyObject *modules = PyImport_GetModuleDict();
    if (unlikely(!modules))
        return NULL;
    imported_module = __Pyx_PyDict_GetItemStr(modules, name);
    Py_XINCREF(imported_module);
#else
    imported_module = PyImport_GetModule(name);
#endif
    return imported_module;
}
#endif
#if PY_MAJOR_VERSION >= 3
static PyObject *__Pyx_ImportDottedModule_WalkParts(PyObject *module, PyObject *name, PyObject *parts_tuple) {
    Py_ssize_t i, nparts;
    nparts = PyTuple_GET_SIZE(parts_tuple);
    for (i=1; i < nparts && module; i++) {
        PyObject *part, *submodule;
#if CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS
        part = PyTuple_GET_ITEM(parts_tuple, i);
#else
        part = PySequence_ITEM(parts_tuple, i);
#endif
        submodule = __Pyx_PyObject_GetAttrStrNoError(module, part);
#if !(CYTHON_ASSUME_SAFE_MACROS && !CYTHON_AVOID_BORROWED_REFS)
        Py_DECREF(part);
#endif
        Py_DECREF(module);
        module = submodule;
    }
    if (unlikely(!module)) {
        return __Pyx__ImportDottedModule_Error(name, parts_tuple, i);
    }
    return module;
}
#endif
static PyObject *__Pyx__ImportDottedModule(PyObject *name, PyObject *parts_tuple) {
#if PY_MAJOR_VERSION < 3
    PyObject *module, *from_list, *star = __pyx_n_s__14;
    CYTHON_UNUSED_VAR(parts_tuple);
    from_list = PyList_New(1);
    if (unlikely(!from_list))
        return NULL;
    Py_INCREF(star);
    PyList_SET_ITEM(from_list, 0, star);
    module = __Pyx_Import(name, from_list, 0);
    Py_DECREF(from_list);
    return module;
#else
    PyObject *imported_module;
    PyObject *module = __Pyx_Import(name, NULL, 0);
    if (!parts_tuple || unlikely(!module))
        return module;
    imported_module = __Pyx__ImportDottedModule_Lookup(name);
    if (likely(imported_module)) {
        Py_DECREF(module);
        return imported_module;
    }
    PyErr_Clear();
    return __Pyx_ImportDottedModule_WalkParts(module, name, parts_tuple);
#endif
}
static PyObject *__Pyx_ImportDottedModule(PyObject *name, PyObject *parts_tuple) {
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX >= 0x030400B1
    PyObject *module = __Pyx__ImportDottedModule_Lookup(name);
    if (likely(module)) {
        PyObject *spec = __Pyx_PyObject_GetAttrStrNoError(module, __pyx_n_s_spec);
        if (likely(spec)) {
            PyObject *unsafe = __Pyx_PyObject_GetAttrStrNoError(spec, __pyx_n_s_initializing);
            if (likely(!unsafe || !__Pyx_PyObject_IsTrue(unsafe))) {
                Py_DECREF(spec);
                spec = NULL;
            }
            Py_XDECREF(unsafe);
        }
        if (likely(!spec)) {
            PyErr_Clear();
            return module;
        }
        Py_DECREF(spec);
        Py_DECREF(module);
    } else if (PyErr_Occurred()) {
        PyErr_Clear();
    }
#endif
    return __Pyx__ImportDottedModule(name, parts_tuple);
}

/* ImportFrom */
static PyObject* __Pyx_ImportFrom(PyObject* module, PyObject* name) {
    PyObject* value = __Pyx_PyObject_GetAttrStr(module, name);
    if (unlikely(!value) && PyErr_ExceptionMatches(PyExc_AttributeError)) {
        const char* module_name_str = 0;
        PyObject* module_name = 0;
        PyObject* module_dot = 0;
        PyObject* full_name = 0;
        PyErr_Clear();
        module_name_str = PyModule_GetName(module);
        if (unlikely(!module_name_str)) { goto modbad; }
        module_name = PyUnicode_FromString(module_name_str);
        if (unlikely(!module_name)) { goto modbad; }
        module_dot = PyUnicode_Concat(module_name, __pyx_kp_u__15);
        if (unlikely(!module_dot)) { goto modbad; }
        full_name = PyUnicode_Concat(module_dot, name);
        if (unlikely(!full_name)) { goto modbad; }
        #if PY_VERSION_HEX < 0x030700A1 || (CYTHON_COMPILING_IN_PYPY && PYPY_VERSION_NUM  < 0x07030400)
        {
            PyObject *modules = PyImport_GetModuleDict();
            if (unlikely(!modules))
                goto modbad;
            value = PyObject_GetItem(modules, full_name);
        }
        #else
        value = PyImport_GetModule(full_name);
        #endif
      modbad:
        Py_XDECREF(full_name);
        Py_XDECREF(module_dot);
        Py_XDECREF(module_name);
    }
    if (unlikely(!value)) {
        PyErr_Format(PyExc_ImportError,
        #if PY_MAJOR_VERSION < 3
            "cannot import name %.230s", PyString_AS_STRING(name));
        #else
            "cannot import name %S", name);
        #endif
    }
    return value;
}

/* PyObjectCallNoArg */
static CYTHON_INLINE PyObject* __Pyx_PyObject_CallNoArg(PyObject *func) {
    PyObject *arg = NULL;
    return __Pyx_PyObject_FastCall(func, (&arg)+1, 0 | __Pyx_PY_VECTORCALL_ARGUMENTS_OFFSET);
}

/* CLineInTraceback */
#ifndef CYTHON_CLINE_IN_TRACEBACK
static int __Pyx_CLineForTraceback(PyThreadState *tstate, int c_line) {
    PyObject *use_cline;
    PyObject *ptype, *pvalue, *ptraceback;
#if CYTHON_COMPILING_IN_CPYTHON
    PyObject **cython_runtime_dict;
#endif
    CYTHON_MAYBE_UNUSED_VAR(tstate);
    if (unlikely(!__pyx_cython_runtime)) {
        return c_line;
    }
    __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
#if CYTHON_COMPILING_IN_CPYTHON
    cython_runtime_dict = _PyObject_GetDictPtr(__pyx_cython_runtime);
    if (likely(cython_runtime_dict)) {
        __PYX_PY_DICT_LOOKUP_IF_MODIFIED(
            use_cline, *cython_runtime_dict,
            __Pyx_PyDict_GetItemStr(*cython_runtime_dict, __pyx_n_s_cline_in_traceback))
    } else
#endif
    {
      PyObject *use_cline_obj = __Pyx_PyObject_GetAttrStrNoError(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback);
      if (use_cline_obj) {
        use_cline = PyObject_Not(use_cline_obj) ? Py_False : Py_True;
        Py_DECREF(use_cline_obj);
      } else {
        PyErr_Clear();
        use_cline = NULL;
      }
    }
    if (!use_cline) {
        c_line = 0;
        (void) PyObject_SetAttr(__pyx_cython_runtime, __pyx_n_s_cline_in_traceback, Py_False);
    }
    else if (use_cline == Py_False || (use_cline != Py_True && PyObject_Not(use_cline) != 0)) {
        c_line = 0;
    }
    __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
    return c_line;
}
#endif

/* CodeObjectCache */
#if !CYTHON_COMPILING_IN_LIMITED_API
static int __pyx_bisect_code_objects(__Pyx_CodeObjectCacheEntry* entries, int count, int code_line) {
    int start = 0, mid = 0, end = count - 1;
    if (end >= 0 && code_line > entries[end].code_line) {
        return count;
    }
    while (start < end) {
        mid = start + (end - start) / 2;
        if (code_line < entries[mid].code_line) {
            end = mid;
        } else if (code_line > entries[mid].code_line) {
             start = mid + 1;
        } else {
            return mid;
        }
    }
    if (code_line <= entries[mid].code_line) {
        return mid;
    } else {
        return mid + 1;
    }
}
static PyCodeObject *__pyx_find_code_object(int code_line) {
    PyCodeObject* code_object;
    int pos;
    if (unlikely(!code_line) || unlikely(!__pyx_code_cache.entries)) {
        return NULL;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if (unlikely(pos >= __pyx_code_cache.count) || unlikely(__pyx_code_cache.entries[pos].code_line != code_line)) {
        return NULL;
    }
    code_object = __pyx_code_cache.entries[pos].code_object;
    Py_INCREF(code_object);
    return code_object;
}
static void __pyx_insert_code_object(int code_line, PyCodeObject* code_object) {
    int pos, i;
    __Pyx_CodeObjectCacheEntry* entries = __pyx_code_cache.entries;
    if (unlikely(!code_line)) {
        return;
    }
    if (unlikely(!entries)) {
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Malloc(64*sizeof(__Pyx_CodeObjectCacheEntry));
        if (likely(entries)) {
            __pyx_code_cache.entries = entries;
            __pyx_code_cache.max_count = 64;
            __pyx_code_cache.count = 1;
            entries[0].code_line = code_line;
            entries[0].code_object = code_object;
            Py_INCREF(code_object);
        }
        return;
    }
    pos = __pyx_bisect_code_objects(__pyx_code_cache.entries, __pyx_code_cache.count, code_line);
    if ((pos < __pyx_code_cache.count) && unlikely(__pyx_code_cache.entries[pos].code_line == code_line)) {
        PyCodeObject* tmp = entries[pos].code_object;
        entries[pos].code_object = code_object;
        Py_DECREF(tmp);
        return;
    }
    if (__pyx_code_cache.count == __pyx_code_cache.max_count) {
        int new_max = __pyx_code_cache.max_count + 64;
        entries = (__Pyx_CodeObjectCacheEntry*)PyMem_Realloc(
            __pyx_code_cache.entries, ((size_t)new_max) * sizeof(__Pyx_CodeObjectCacheEntry));
        if (unlikely(!entries)) {
            return;
        }
        __pyx_code_cache.entries = entries;
        __pyx_code_cache.max_count = new_max;
    }
    for (i=__pyx_code_cache.count; i>pos; i--) {
        entries[i] = entries[i-1];
    }
    entries[pos].code_line = code_line;
    entries[pos].code_object = code_object;
    __pyx_code_cache.count++;
    Py_INCREF(code_object);
}
#endif

/* AddTraceback */
#include "compile.h"
#include "frameobject.h"
#include "traceback.h"
#if PY_VERSION_HEX >= 0x030b00a6 && !CYTHON_COMPILING_IN_LIMITED_API
  #ifndef Py_BUILD_CORE
    #define Py_BUILD_CORE 1
  #endif
  #include "internal/pycore_frame.h"
#endif
#if CYTHON_COMPILING_IN_LIMITED_API
static PyObject *__Pyx_PyCode_Replace_For_AddTraceback(PyObject *code, PyObject *scratch_dict,
                                                       PyObject *firstlineno, PyObject *name) {
    PyObject *replace = NULL;
    if (unlikely(PyDict_SetItemString(scratch_dict, "co_firstlineno", firstlineno))) return NULL;
    if (unlikely(PyDict_SetItemString(scratch_dict, "co_name", name))) return NULL;
    replace = PyObject_GetAttrString(code, "replace");
    if (likely(replace)) {
        PyObject *result;
        result = PyObject_Call(replace, __pyx_empty_tuple, scratch_dict);
        Py_DECREF(replace);
        return result;
    }
    #if __PYX_LIMITED_VERSION_HEX < 0x030780000
    PyErr_Clear();
    {
        PyObject *compiled = NULL, *result = NULL;
        if (unlikely(PyDict_SetItemString(scratch_dict, "code", code))) return NULL;
        if (unlikely(PyDict_SetItemString(scratch_dict, "type", (PyObject*)(&PyType_Type)))) return NULL;
        compiled = Py_CompileString(
            "out = type(code)(\n"
            "  code.co_argcount, code.co_kwonlyargcount, code.co_nlocals, code.co_stacksize,\n"
            "  code.co_flags, code.co_code, code.co_consts, code.co_names,\n"
            "  code.co_varnames, code.co_filename, co_name, co_firstlineno,\n"
            "  code.co_lnotab)\n", "<dummy>", Py_file_input);
        if (!compiled) return NULL;
        result = PyEval_EvalCode(compiled, scratch_dict, scratch_dict);
        Py_DECREF(compiled);
        if (!result) PyErr_Print();
        Py_DECREF(result);
        result = PyDict_GetItemString(scratch_dict, "out");
        if (result) Py_INCREF(result);
        return result;
    }
    #endif
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyObject *code_object = NULL, *py_py_line = NULL, *py_funcname = NULL, *dict = NULL;
    PyObject *replace = NULL, *getframe = NULL, *frame = NULL;
    PyObject *exc_type, *exc_value, *exc_traceback;
    int success = 0;
    if (c_line) {
        (void) __pyx_cfilenm;
        (void) __Pyx_CLineForTraceback(__Pyx_PyThreadState_Current, c_line);
    }
    PyErr_Fetch(&exc_type, &exc_value, &exc_traceback);
    code_object = Py_CompileString("_getframe()", filename, Py_eval_input);
    if (unlikely(!code_object)) goto bad;
    py_py_line = PyLong_FromLong(py_line);
    if (unlikely(!py_py_line)) goto bad;
    py_funcname = PyUnicode_FromString(funcname);
    if (unlikely(!py_funcname)) goto bad;
    dict = PyDict_New();
    if (unlikely(!dict)) goto bad;
    {
        PyObject *old_code_object = code_object;
        code_object = __Pyx_PyCode_Replace_For_AddTraceback(code_object, dict, py_py_line, py_funcname);
        Py_DECREF(old_code_object);
    }
    if (unlikely(!code_object)) goto bad;
    getframe = PySys_GetObject("_getframe");
    if (unlikely(!getframe)) goto bad;
    if (unlikely(PyDict_SetItemString(dict, "_getframe", getframe))) goto bad;
    frame = PyEval_EvalCode(code_object, dict, dict);
    if (unlikely(!frame) || frame == Py_None) goto bad;
    success = 1;
  bad:
    PyErr_Restore(exc_type, exc_value, exc_traceback);
    Py_XDECREF(code_object);
    Py_XDECREF(py_py_line);
    Py_XDECREF(py_funcname);
    Py_XDECREF(dict);
    Py_XDECREF(replace);
    if (success) {
        PyTraceBack_Here(
            (struct _frame*)frame);
    }
    Py_XDECREF(frame);
}
#else
static PyCodeObject* __Pyx_CreateCodeObjectForTraceback(
            const char *funcname, int c_line,
            int py_line, const char *filename) {
    PyCodeObject *py_code = NULL;
    PyObject *py_funcname = NULL;
    #if PY_MAJOR_VERSION < 3
    PyObject *py_srcfile = NULL;
    py_srcfile = PyString_FromString(filename);
    if (!py_srcfile) goto bad;
    #endif
    if (c_line) {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        if (!py_funcname) goto bad;
        #else
        py_funcname = PyUnicode_FromFormat( "%s (%s:%d)", funcname, __pyx_cfilenm, c_line);
        if (!py_funcname) goto bad;
        funcname = PyUnicode_AsUTF8(py_funcname);
        if (!funcname) goto bad;
        #endif
    }
    else {
        #if PY_MAJOR_VERSION < 3
        py_funcname = PyString_FromString(funcname);
        if (!py_funcname) goto bad;
        #endif
    }
    #if PY_MAJOR_VERSION < 3
    py_code = __Pyx_PyCode_New(
        0,
        0,
        0,
        0,
        0,
        0,
        __pyx_empty_bytes, /*PyObject *code,*/
        __pyx_empty_tuple, /*PyObject *consts,*/
        __pyx_empty_tuple, /*PyObject *names,*/
        __pyx_empty_tuple, /*PyObject *varnames,*/
        __pyx_empty_tuple, /*PyObject *freevars,*/
        __pyx_empty_tuple, /*PyObject *cellvars,*/
        py_srcfile,   /*PyObject *filename,*/
        py_funcname,  /*PyObject *name,*/
        py_line,
        __pyx_empty_bytes  /*PyObject *lnotab*/
    );
    Py_DECREF(py_srcfile);
    #else
    py_code = PyCode_NewEmpty(filename, funcname, py_line);
    #endif
    Py_XDECREF(py_funcname);  // XDECREF since it's only set on Py3 if cline
    return py_code;
bad:
    Py_XDECREF(py_funcname);
    #if PY_MAJOR_VERSION < 3
    Py_XDECREF(py_srcfile);
    #endif
    return NULL;
}
static void __Pyx_AddTraceback(const char *funcname, int c_line,
                               int py_line, const char *filename) {
    PyCodeObject *py_code = 0;
    PyFrameObject *py_frame = 0;
    PyThreadState *tstate = __Pyx_PyThreadState_Current;
    PyObject *ptype, *pvalue, *ptraceback;
    if (c_line) {
        c_line = __Pyx_CLineForTraceback(tstate, c_line);
    }
    py_code = __pyx_find_code_object(c_line ? -c_line : py_line);
    if (!py_code) {
        __Pyx_ErrFetchInState(tstate, &ptype, &pvalue, &ptraceback);
        py_code = __Pyx_CreateCodeObjectForTraceback(
            funcname, c_line, py_line, filename);
        if (!py_code) {
            /* If the code object creation fails, then we should clear the
               fetched exception references and propagate the new exception */
            Py_XDECREF(ptype);
            Py_XDECREF(pvalue);
            Py_XDECREF(ptraceback);
            goto bad;
        }
        __Pyx_ErrRestoreInState(tstate, ptype, pvalue, ptraceback);
        __pyx_insert_code_object(c_line ? -c_line : py_line, py_code);
    }
    py_frame = PyFrame_New(
        tstate,            /*PyThreadState *tstate,*/
        py_code,           /*PyCodeObject *code,*/
        __pyx_d,    /*PyObject *globals,*/
        0                  /*PyObject *locals*/
    );
    if (!py_frame) goto bad;
    __Pyx_PyFrame_SetLineNumber(py_frame, py_line);
    PyTraceBack_Here(py_frame);
bad:
    Py_XDECREF(py_code);
    Py_XDECREF(py_frame);
}
#endif

/* CIntFromPyVerify */
#define __PYX_VERIFY_RETURN_INT(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 0)
#define __PYX_VERIFY_RETURN_INT_EXC(target_type, func_type, func_value)\
    __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, 1)
#define __PYX__VERIFY_RETURN_INT(target_type, func_type, func_value, exc)\
    {\
        func_type value = func_value;\
        if (sizeof(target_type) < sizeof(func_type)) {\
            if (unlikely(value != (func_type) (target_type) value)) {\
                func_type zero = 0;\
                if (exc && unlikely(value == (func_type)-1 && PyErr_Occurred()))\
                    return (target_type) -1;\
                if (is_unsigned && unlikely(value < zero))\
                    goto raise_neg_overflow;\
                else\
                    goto raise_overflow;\
            }\
        }\
        return (target_type) value;\
    }

/* CIntFromPy */
static CYTHON_INLINE int __Pyx_PyInt_As_int(PyObject *x) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const int neg_one = (int) -1, const_zero = (int) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if ((sizeof(int) < sizeof(long))) {
            __PYX_VERIFY_RETURN_INT(int, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            if (unlikely(__Pyx_PyLong_IsNeg(x))) {
                goto raise_neg_overflow;
            } else if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(int, __Pyx_compact_upylong, __Pyx_PyLong_CompactValueUnsigned(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_DigitCount(x)) {
                    case 2:
                        if ((8 * sizeof(int) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) >= 2 * PyLong_SHIFT)) {
                                return (int) (((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(int) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) >= 3 * PyLong_SHIFT)) {
                                return (int) (((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(int) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) >= 4 * PyLong_SHIFT)) {
                                return (int) (((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0]));
                            }
                        }
                        break;
                }
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX < 0x030C00A7
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if ((sizeof(int) <= sizeof(unsigned long))) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(int) <= sizeof(unsigned PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(int, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(int, __Pyx_compact_pylong, __Pyx_PyLong_CompactValue(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_SignedDigitCount(x)) {
                    case -2:
                        if ((8 * sizeof(int) - 1 > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 2 * PyLong_SHIFT)) {
                                return (int) (((int)-1)*(((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                    case 2:
                        if ((8 * sizeof(int) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 2 * PyLong_SHIFT)) {
                                return (int) ((((((int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                    case -3:
                        if ((8 * sizeof(int) - 1 > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 3 * PyLong_SHIFT)) {
                                return (int) (((int)-1)*(((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(int) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 3 * PyLong_SHIFT)) {
                                return (int) ((((((((int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                    case -4:
                        if ((8 * sizeof(int) - 1 > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 4 * PyLong_SHIFT)) {
                                return (int) (((int)-1)*(((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(int) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int) - 1 > 4 * PyLong_SHIFT)) {
                                return (int) ((((((((((int)digits[3]) << PyLong_SHIFT) | (int)digits[2]) << PyLong_SHIFT) | (int)digits[1]) << PyLong_SHIFT) | (int)digits[0])));
                            }
                        }
                        break;
                }
            }
#endif
            if ((sizeof(int) <= sizeof(long))) {
                __PYX_VERIFY_RETURN_INT_EXC(int, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(int) <= sizeof(PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(int, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
            int val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
#if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
#endif
            if (likely(v)) {
                int ret = -1;
#if !(CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API) || defined(_PyLong_AsByteArray)
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                ret = _PyLong_AsByteArray((PyLongObject *)v,
                                           bytes, sizeof(val),
                                           is_little, !is_unsigned);
#else
                PyObject *stepval = NULL, *mask = NULL, *shift = NULL;
                int bits, remaining_bits, is_negative = 0;
                long idigit;
                int chunk_size = (sizeof(long) < 8) ? 30 : 62;
                if (unlikely(!PyLong_CheckExact(v))) {
                    PyObject *tmp = v;
                    v = PyNumber_Long(v);
                    assert(PyLong_CheckExact(v));
                    Py_DECREF(tmp);
                    if (unlikely(!v)) return (int) -1;
                }
#if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                if (Py_SIZE(x) == 0)
                    return (int) 0;
                is_negative = Py_SIZE(x) < 0;
#else
                {
                    int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                    if (unlikely(result < 0))
                        return (int) -1;
                    is_negative = result == 1;
                }
#endif
                if (is_unsigned && unlikely(is_negative)) {
                    goto raise_neg_overflow;
                } else if (is_negative) {
                    stepval = PyNumber_Invert(v);
                    if (unlikely(!stepval))
                        return (int) -1;
                } else {
                    stepval = __Pyx_NewRef(v);
                }
                val = (int) 0;
                mask = PyLong_FromLong((1L << chunk_size) - 1); if (unlikely(!mask)) goto done;
                shift = PyLong_FromLong(chunk_size); if (unlikely(!shift)) goto done;
                for (bits = 0; bits < (int) sizeof(int) * 8 - chunk_size; bits += chunk_size) {
                    PyObject *tmp, *digit;
                    digit = PyNumber_And(stepval, mask);
                    if (unlikely(!digit)) goto done;
                    idigit = PyLong_AsLong(digit);
                    Py_DECREF(digit);
                    if (unlikely(idigit < 0)) goto done;
                    tmp = PyNumber_Rshift(stepval, shift);
                    if (unlikely(!tmp)) goto done;
                    Py_DECREF(stepval); stepval = tmp;
                    val |= ((int) idigit) << bits;
                    #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                    if (Py_SIZE(stepval) == 0)
                        goto unpacking_done;
                    #endif
                }
                idigit = PyLong_AsLong(stepval);
                if (unlikely(idigit < 0)) goto done;
                remaining_bits = ((int) sizeof(int) * 8) - bits - (is_unsigned ? 0 : 1);
                if (unlikely(idigit >= (1L << remaining_bits)))
                    goto raise_overflow;
                val |= ((int) idigit) << bits;
            #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
            unpacking_done:
            #endif
                if (!is_unsigned) {
                    if (unlikely(val & (((int) 1) << (sizeof(int) * 8 - 1))))
                        goto raise_overflow;
                    if (is_negative)
                        val = ~val;
                }
                ret = 0;
            done:
                Py_XDECREF(shift);
                Py_XDECREF(mask);
                Py_XDECREF(stepval);
#endif
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
            return (int) -1;
        }
    } else {
        int val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int) -1;
        val = __Pyx_PyInt_As_int(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int");
    return (int) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int");
    return (int) -1;
}

/* CIntFromPy */
static CYTHON_INLINE char __Pyx_PyInt_As_char(PyObject *x) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const char neg_one = (char) -1, const_zero = (char) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if ((sizeof(char) < sizeof(long))) {
            __PYX_VERIFY_RETURN_INT(char, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (char) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            if (unlikely(__Pyx_PyLong_IsNeg(x))) {
                goto raise_neg_overflow;
            } else if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(char, __Pyx_compact_upylong, __Pyx_PyLong_CompactValueUnsigned(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_DigitCount(x)) {
                    case 2:
                        if ((8 * sizeof(char) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) >= 2 * PyLong_SHIFT)) {
                                return (char) (((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(char) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) >= 3 * PyLong_SHIFT)) {
                                return (char) (((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(char) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) >= 4 * PyLong_SHIFT)) {
                                return (char) (((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0]));
                            }
                        }
                        break;
                }
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX < 0x030C00A7
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (char) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if ((sizeof(char) <= sizeof(unsigned long))) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(char) <= sizeof(unsigned PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(char, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(char, __Pyx_compact_pylong, __Pyx_PyLong_CompactValue(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_SignedDigitCount(x)) {
                    case -2:
                        if ((8 * sizeof(char) - 1 > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 2 * PyLong_SHIFT)) {
                                return (char) (((char)-1)*(((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                    case 2:
                        if ((8 * sizeof(char) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 2 * PyLong_SHIFT)) {
                                return (char) ((((((char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                    case -3:
                        if ((8 * sizeof(char) - 1 > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 3 * PyLong_SHIFT)) {
                                return (char) (((char)-1)*(((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(char) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 3 * PyLong_SHIFT)) {
                                return (char) ((((((((char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                    case -4:
                        if ((8 * sizeof(char) - 1 > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 4 * PyLong_SHIFT)) {
                                return (char) (((char)-1)*(((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(char) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(char, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(char) - 1 > 4 * PyLong_SHIFT)) {
                                return (char) ((((((((((char)digits[3]) << PyLong_SHIFT) | (char)digits[2]) << PyLong_SHIFT) | (char)digits[1]) << PyLong_SHIFT) | (char)digits[0])));
                            }
                        }
                        break;
                }
            }
#endif
            if ((sizeof(char) <= sizeof(long))) {
                __PYX_VERIFY_RETURN_INT_EXC(char, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(char) <= sizeof(PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(char, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
            char val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
#if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
#endif
            if (likely(v)) {
                int ret = -1;
#if !(CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API) || defined(_PyLong_AsByteArray)
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                ret = _PyLong_AsByteArray((PyLongObject *)v,
                                           bytes, sizeof(val),
                                           is_little, !is_unsigned);
#else
                PyObject *stepval = NULL, *mask = NULL, *shift = NULL;
                int bits, remaining_bits, is_negative = 0;
                long idigit;
                int chunk_size = (sizeof(long) < 8) ? 30 : 62;
                if (unlikely(!PyLong_CheckExact(v))) {
                    PyObject *tmp = v;
                    v = PyNumber_Long(v);
                    assert(PyLong_CheckExact(v));
                    Py_DECREF(tmp);
                    if (unlikely(!v)) return (char) -1;
                }
#if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                if (Py_SIZE(x) == 0)
                    return (char) 0;
                is_negative = Py_SIZE(x) < 0;
#else
                {
                    int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                    if (unlikely(result < 0))
                        return (char) -1;
                    is_negative = result == 1;
                }
#endif
                if (is_unsigned && unlikely(is_negative)) {
                    goto raise_neg_overflow;
                } else if (is_negative) {
                    stepval = PyNumber_Invert(v);
                    if (unlikely(!stepval))
                        return (char) -1;
                } else {
                    stepval = __Pyx_NewRef(v);
                }
                val = (char) 0;
                mask = PyLong_FromLong((1L << chunk_size) - 1); if (unlikely(!mask)) goto done;
                shift = PyLong_FromLong(chunk_size); if (unlikely(!shift)) goto done;
                for (bits = 0; bits < (int) sizeof(char) * 8 - chunk_size; bits += chunk_size) {
                    PyObject *tmp, *digit;
                    digit = PyNumber_And(stepval, mask);
                    if (unlikely(!digit)) goto done;
                    idigit = PyLong_AsLong(digit);
                    Py_DECREF(digit);
                    if (unlikely(idigit < 0)) goto done;
                    tmp = PyNumber_Rshift(stepval, shift);
                    if (unlikely(!tmp)) goto done;
                    Py_DECREF(stepval); stepval = tmp;
                    val |= ((char) idigit) << bits;
                    #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                    if (Py_SIZE(stepval) == 0)
                        goto unpacking_done;
                    #endif
                }
                idigit = PyLong_AsLong(stepval);
                if (unlikely(idigit < 0)) goto done;
                remaining_bits = ((int) sizeof(char) * 8) - bits - (is_unsigned ? 0 : 1);
                if (unlikely(idigit >= (1L << remaining_bits)))
                    goto raise_overflow;
                val |= ((char) idigit) << bits;
            #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
            unpacking_done:
            #endif
                if (!is_unsigned) {
                    if (unlikely(val & (((char) 1) << (sizeof(char) * 8 - 1))))
                        goto raise_overflow;
                    if (is_negative)
                        val = ~val;
                }
                ret = 0;
            done:
                Py_XDECREF(shift);
                Py_XDECREF(mask);
                Py_XDECREF(stepval);
#endif
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
            return (char) -1;
        }
    } else {
        char val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (char) -1;
        val = __Pyx_PyInt_As_char(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to char");
    return (char) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to char");
    return (char) -1;
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int(int value) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const int neg_one = (int) -1, const_zero = (int) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
#if !CYTHON_COMPILING_IN_LIMITED_API
        return _PyLong_FromByteArray(bytes, sizeof(int),
                                     little, !is_unsigned);
#else
        PyObject *from_bytes, *result = NULL;
        PyObject *py_bytes = NULL, *arg_tuple = NULL, *kwds = NULL, *order_str = NULL;
        from_bytes = PyObject_GetAttrString((PyObject*)&PyInt_Type, "from_bytes");
        if (!from_bytes) return NULL;
        py_bytes = PyBytes_FromStringAndSize((char*)bytes, sizeof(int));
        if (!py_bytes) goto limited_bad;
        order_str = PyUnicode_FromString(little ? "little" : "big");
        if (!order_str) goto limited_bad;
        arg_tuple = PyTuple_Pack(2, py_bytes, order_str);
        if (!arg_tuple) goto limited_bad;
        kwds = PyDict_New();
        if (!kwds) goto limited_bad;
        if (PyDict_SetItemString(kwds, "signed", __Pyx_NewRef(!is_unsigned ? Py_True : Py_False))) goto limited_bad;
        result = PyObject_Call(from_bytes, arg_tuple, kwds);
        limited_bad:
        Py_XDECREF(from_bytes);
        Py_XDECREF(py_bytes);
        Py_XDECREF(order_str);
        Py_XDECREF(arg_tuple);
        Py_XDECREF(kwds);
        return result;
#endif
    }
}

/* CIntFromPy */
static CYTHON_INLINE int32_t __Pyx_PyInt_As_int32_t(PyObject *x) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const int32_t neg_one = (int32_t) -1, const_zero = (int32_t) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if ((sizeof(int32_t) < sizeof(long))) {
            __PYX_VERIFY_RETURN_INT(int32_t, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (int32_t) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            if (unlikely(__Pyx_PyLong_IsNeg(x))) {
                goto raise_neg_overflow;
            } else if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(int32_t, __Pyx_compact_upylong, __Pyx_PyLong_CompactValueUnsigned(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_DigitCount(x)) {
                    case 2:
                        if ((8 * sizeof(int32_t) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) >= 2 * PyLong_SHIFT)) {
                                return (int32_t) (((((int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0]));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(int32_t) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) >= 3 * PyLong_SHIFT)) {
                                return (int32_t) (((((((int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0]));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(int32_t) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) >= 4 * PyLong_SHIFT)) {
                                return (int32_t) (((((((((int32_t)digits[3]) << PyLong_SHIFT) | (int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0]));
                            }
                        }
                        break;
                }
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX < 0x030C00A7
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (int32_t) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if ((sizeof(int32_t) <= sizeof(unsigned long))) {
                __PYX_VERIFY_RETURN_INT_EXC(int32_t, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(int32_t) <= sizeof(unsigned PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(int32_t, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(int32_t, __Pyx_compact_pylong, __Pyx_PyLong_CompactValue(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_SignedDigitCount(x)) {
                    case -2:
                        if ((8 * sizeof(int32_t) - 1 > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 2 * PyLong_SHIFT)) {
                                return (int32_t) (((int32_t)-1)*(((((int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                    case 2:
                        if ((8 * sizeof(int32_t) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 2 * PyLong_SHIFT)) {
                                return (int32_t) ((((((int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                    case -3:
                        if ((8 * sizeof(int32_t) - 1 > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 3 * PyLong_SHIFT)) {
                                return (int32_t) (((int32_t)-1)*(((((((int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(int32_t) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 3 * PyLong_SHIFT)) {
                                return (int32_t) ((((((((int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                    case -4:
                        if ((8 * sizeof(int32_t) - 1 > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 4 * PyLong_SHIFT)) {
                                return (int32_t) (((int32_t)-1)*(((((((((int32_t)digits[3]) << PyLong_SHIFT) | (int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(int32_t) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(int32_t, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(int32_t) - 1 > 4 * PyLong_SHIFT)) {
                                return (int32_t) ((((((((((int32_t)digits[3]) << PyLong_SHIFT) | (int32_t)digits[2]) << PyLong_SHIFT) | (int32_t)digits[1]) << PyLong_SHIFT) | (int32_t)digits[0])));
                            }
                        }
                        break;
                }
            }
#endif
            if ((sizeof(int32_t) <= sizeof(long))) {
                __PYX_VERIFY_RETURN_INT_EXC(int32_t, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(int32_t) <= sizeof(PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(int32_t, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
            int32_t val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
#if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
#endif
            if (likely(v)) {
                int ret = -1;
#if !(CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API) || defined(_PyLong_AsByteArray)
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                ret = _PyLong_AsByteArray((PyLongObject *)v,
                                           bytes, sizeof(val),
                                           is_little, !is_unsigned);
#else
                PyObject *stepval = NULL, *mask = NULL, *shift = NULL;
                int bits, remaining_bits, is_negative = 0;
                long idigit;
                int chunk_size = (sizeof(long) < 8) ? 30 : 62;
                if (unlikely(!PyLong_CheckExact(v))) {
                    PyObject *tmp = v;
                    v = PyNumber_Long(v);
                    assert(PyLong_CheckExact(v));
                    Py_DECREF(tmp);
                    if (unlikely(!v)) return (int32_t) -1;
                }
#if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                if (Py_SIZE(x) == 0)
                    return (int32_t) 0;
                is_negative = Py_SIZE(x) < 0;
#else
                {
                    int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                    if (unlikely(result < 0))
                        return (int32_t) -1;
                    is_negative = result == 1;
                }
#endif
                if (is_unsigned && unlikely(is_negative)) {
                    goto raise_neg_overflow;
                } else if (is_negative) {
                    stepval = PyNumber_Invert(v);
                    if (unlikely(!stepval))
                        return (int32_t) -1;
                } else {
                    stepval = __Pyx_NewRef(v);
                }
                val = (int32_t) 0;
                mask = PyLong_FromLong((1L << chunk_size) - 1); if (unlikely(!mask)) goto done;
                shift = PyLong_FromLong(chunk_size); if (unlikely(!shift)) goto done;
                for (bits = 0; bits < (int) sizeof(int32_t) * 8 - chunk_size; bits += chunk_size) {
                    PyObject *tmp, *digit;
                    digit = PyNumber_And(stepval, mask);
                    if (unlikely(!digit)) goto done;
                    idigit = PyLong_AsLong(digit);
                    Py_DECREF(digit);
                    if (unlikely(idigit < 0)) goto done;
                    tmp = PyNumber_Rshift(stepval, shift);
                    if (unlikely(!tmp)) goto done;
                    Py_DECREF(stepval); stepval = tmp;
                    val |= ((int32_t) idigit) << bits;
                    #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                    if (Py_SIZE(stepval) == 0)
                        goto unpacking_done;
                    #endif
                }
                idigit = PyLong_AsLong(stepval);
                if (unlikely(idigit < 0)) goto done;
                remaining_bits = ((int) sizeof(int32_t) * 8) - bits - (is_unsigned ? 0 : 1);
                if (unlikely(idigit >= (1L << remaining_bits)))
                    goto raise_overflow;
                val |= ((int32_t) idigit) << bits;
            #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
            unpacking_done:
            #endif
                if (!is_unsigned) {
                    if (unlikely(val & (((int32_t) 1) << (sizeof(int32_t) * 8 - 1))))
                        goto raise_overflow;
                    if (is_negative)
                        val = ~val;
                }
                ret = 0;
            done:
                Py_XDECREF(shift);
                Py_XDECREF(mask);
                Py_XDECREF(stepval);
#endif
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
            return (int32_t) -1;
        }
    } else {
        int32_t val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (int32_t) -1;
        val = __Pyx_PyInt_As_int32_t(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to int32_t");
    return (int32_t) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to int32_t");
    return (int32_t) -1;
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_long(long value) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const long neg_one = (long) -1, const_zero = (long) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(long) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(long) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(long) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(long) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
#if !CYTHON_COMPILING_IN_LIMITED_API
        return _PyLong_FromByteArray(bytes, sizeof(long),
                                     little, !is_unsigned);
#else
        PyObject *from_bytes, *result = NULL;
        PyObject *py_bytes = NULL, *arg_tuple = NULL, *kwds = NULL, *order_str = NULL;
        from_bytes = PyObject_GetAttrString((PyObject*)&PyInt_Type, "from_bytes");
        if (!from_bytes) return NULL;
        py_bytes = PyBytes_FromStringAndSize((char*)bytes, sizeof(long));
        if (!py_bytes) goto limited_bad;
        order_str = PyUnicode_FromString(little ? "little" : "big");
        if (!order_str) goto limited_bad;
        arg_tuple = PyTuple_Pack(2, py_bytes, order_str);
        if (!arg_tuple) goto limited_bad;
        kwds = PyDict_New();
        if (!kwds) goto limited_bad;
        if (PyDict_SetItemString(kwds, "signed", __Pyx_NewRef(!is_unsigned ? Py_True : Py_False))) goto limited_bad;
        result = PyObject_Call(from_bytes, arg_tuple, kwds);
        limited_bad:
        Py_XDECREF(from_bytes);
        Py_XDECREF(py_bytes);
        Py_XDECREF(order_str);
        Py_XDECREF(arg_tuple);
        Py_XDECREF(kwds);
        return result;
#endif
    }
}

/* CIntToPy */
static CYTHON_INLINE PyObject* __Pyx_PyInt_From_int32_t(int32_t value) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const int32_t neg_one = (int32_t) -1, const_zero = (int32_t) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
    if (is_unsigned) {
        if (sizeof(int32_t) < sizeof(long)) {
            return PyInt_FromLong((long) value);
        } else if (sizeof(int32_t) <= sizeof(unsigned long)) {
            return PyLong_FromUnsignedLong((unsigned long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int32_t) <= sizeof(unsigned PY_LONG_LONG)) {
            return PyLong_FromUnsignedLongLong((unsigned PY_LONG_LONG) value);
#endif
        }
    } else {
        if (sizeof(int32_t) <= sizeof(long)) {
            return PyInt_FromLong((long) value);
#ifdef HAVE_LONG_LONG
        } else if (sizeof(int32_t) <= sizeof(PY_LONG_LONG)) {
            return PyLong_FromLongLong((PY_LONG_LONG) value);
#endif
        }
    }
    {
        int one = 1; int little = (int)*(unsigned char *)&one;
        unsigned char *bytes = (unsigned char *)&value;
#if !CYTHON_COMPILING_IN_LIMITED_API
        return _PyLong_FromByteArray(bytes, sizeof(int32_t),
                                     little, !is_unsigned);
#else
        PyObject *from_bytes, *result = NULL;
        PyObject *py_bytes = NULL, *arg_tuple = NULL, *kwds = NULL, *order_str = NULL;
        from_bytes = PyObject_GetAttrString((PyObject*)&PyInt_Type, "from_bytes");
        if (!from_bytes) return NULL;
        py_bytes = PyBytes_FromStringAndSize((char*)bytes, sizeof(int32_t));
        if (!py_bytes) goto limited_bad;
        order_str = PyUnicode_FromString(little ? "little" : "big");
        if (!order_str) goto limited_bad;
        arg_tuple = PyTuple_Pack(2, py_bytes, order_str);
        if (!arg_tuple) goto limited_bad;
        kwds = PyDict_New();
        if (!kwds) goto limited_bad;
        if (PyDict_SetItemString(kwds, "signed", __Pyx_NewRef(!is_unsigned ? Py_True : Py_False))) goto limited_bad;
        result = PyObject_Call(from_bytes, arg_tuple, kwds);
        limited_bad:
        Py_XDECREF(from_bytes);
        Py_XDECREF(py_bytes);
        Py_XDECREF(order_str);
        Py_XDECREF(arg_tuple);
        Py_XDECREF(kwds);
        return result;
#endif
    }
}

/* FormatTypeName */
#if CYTHON_COMPILING_IN_LIMITED_API
static __Pyx_TypeName
__Pyx_PyType_GetName(PyTypeObject* tp)
{
    PyObject *name = __Pyx_PyObject_GetAttrStr((PyObject *)tp,
                                               __pyx_n_s_name_2);
    if (unlikely(name == NULL) || unlikely(!PyUnicode_Check(name))) {
        PyErr_Clear();
        Py_XDECREF(name);
        name = __Pyx_NewRef(__pyx_n_s__33);
    }
    return name;
}
#endif

/* CIntFromPy */
static CYTHON_INLINE long __Pyx_PyInt_As_long(PyObject *x) {
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic push
#pragma GCC diagnostic ignored "-Wconversion"
#endif
    const long neg_one = (long) -1, const_zero = (long) 0;
#ifdef __Pyx_HAS_GCC_DIAGNOSTIC
#pragma GCC diagnostic pop
#endif
    const int is_unsigned = neg_one > const_zero;
#if PY_MAJOR_VERSION < 3
    if (likely(PyInt_Check(x))) {
        if ((sizeof(long) < sizeof(long))) {
            __PYX_VERIFY_RETURN_INT(long, long, PyInt_AS_LONG(x))
        } else {
            long val = PyInt_AS_LONG(x);
            if (is_unsigned && unlikely(val < 0)) {
                goto raise_neg_overflow;
            }
            return (long) val;
        }
    } else
#endif
    if (likely(PyLong_Check(x))) {
        if (is_unsigned) {
#if CYTHON_USE_PYLONG_INTERNALS
            if (unlikely(__Pyx_PyLong_IsNeg(x))) {
                goto raise_neg_overflow;
            } else if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(long, __Pyx_compact_upylong, __Pyx_PyLong_CompactValueUnsigned(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_DigitCount(x)) {
                    case 2:
                        if ((8 * sizeof(long) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) >= 2 * PyLong_SHIFT)) {
                                return (long) (((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(long) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) >= 3 * PyLong_SHIFT)) {
                                return (long) (((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(long) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) >= 4 * PyLong_SHIFT)) {
                                return (long) (((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0]));
                            }
                        }
                        break;
                }
            }
#endif
#if CYTHON_COMPILING_IN_CPYTHON && PY_VERSION_HEX < 0x030C00A7
            if (unlikely(Py_SIZE(x) < 0)) {
                goto raise_neg_overflow;
            }
#else
            {
                int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                if (unlikely(result < 0))
                    return (long) -1;
                if (unlikely(result == 1))
                    goto raise_neg_overflow;
            }
#endif
            if ((sizeof(long) <= sizeof(unsigned long))) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned long, PyLong_AsUnsignedLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(long) <= sizeof(unsigned PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(long, unsigned PY_LONG_LONG, PyLong_AsUnsignedLongLong(x))
#endif
            }
        } else {
#if CYTHON_USE_PYLONG_INTERNALS
            if (__Pyx_PyLong_IsCompact(x)) {
                __PYX_VERIFY_RETURN_INT(long, __Pyx_compact_pylong, __Pyx_PyLong_CompactValue(x))
            } else {
                const digit* digits = __Pyx_PyLong_Digits(x);
                assert(__Pyx_PyLong_DigitCount(x) > 1);
                switch (__Pyx_PyLong_SignedDigitCount(x)) {
                    case -2:
                        if ((8 * sizeof(long) - 1 > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 2 * PyLong_SHIFT)) {
                                return (long) (((long)-1)*(((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                    case 2:
                        if ((8 * sizeof(long) > 1 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 2 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 2 * PyLong_SHIFT)) {
                                return (long) ((((((long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                    case -3:
                        if ((8 * sizeof(long) - 1 > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 3 * PyLong_SHIFT)) {
                                return (long) (((long)-1)*(((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                    case 3:
                        if ((8 * sizeof(long) > 2 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 3 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 3 * PyLong_SHIFT)) {
                                return (long) ((((((((long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                    case -4:
                        if ((8 * sizeof(long) - 1 > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, long, -(long) (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 4 * PyLong_SHIFT)) {
                                return (long) (((long)-1)*(((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                    case 4:
                        if ((8 * sizeof(long) > 3 * PyLong_SHIFT)) {
                            if ((8 * sizeof(unsigned long) > 4 * PyLong_SHIFT)) {
                                __PYX_VERIFY_RETURN_INT(long, unsigned long, (((((((((unsigned long)digits[3]) << PyLong_SHIFT) | (unsigned long)digits[2]) << PyLong_SHIFT) | (unsigned long)digits[1]) << PyLong_SHIFT) | (unsigned long)digits[0])))
                            } else if ((8 * sizeof(long) - 1 > 4 * PyLong_SHIFT)) {
                                return (long) ((((((((((long)digits[3]) << PyLong_SHIFT) | (long)digits[2]) << PyLong_SHIFT) | (long)digits[1]) << PyLong_SHIFT) | (long)digits[0])));
                            }
                        }
                        break;
                }
            }
#endif
            if ((sizeof(long) <= sizeof(long))) {
                __PYX_VERIFY_RETURN_INT_EXC(long, long, PyLong_AsLong(x))
#ifdef HAVE_LONG_LONG
            } else if ((sizeof(long) <= sizeof(PY_LONG_LONG))) {
                __PYX_VERIFY_RETURN_INT_EXC(long, PY_LONG_LONG, PyLong_AsLongLong(x))
#endif
            }
        }
        {
            long val;
            PyObject *v = __Pyx_PyNumber_IntOrLong(x);
#if PY_MAJOR_VERSION < 3
            if (likely(v) && !PyLong_Check(v)) {
                PyObject *tmp = v;
                v = PyNumber_Long(tmp);
                Py_DECREF(tmp);
            }
#endif
            if (likely(v)) {
                int ret = -1;
#if !(CYTHON_COMPILING_IN_PYPY || CYTHON_COMPILING_IN_LIMITED_API) || defined(_PyLong_AsByteArray)
                int one = 1; int is_little = (int)*(unsigned char *)&one;
                unsigned char *bytes = (unsigned char *)&val;
                ret = _PyLong_AsByteArray((PyLongObject *)v,
                                           bytes, sizeof(val),
                                           is_little, !is_unsigned);
#else
                PyObject *stepval = NULL, *mask = NULL, *shift = NULL;
                int bits, remaining_bits, is_negative = 0;
                long idigit;
                int chunk_size = (sizeof(long) < 8) ? 30 : 62;
                if (unlikely(!PyLong_CheckExact(v))) {
                    PyObject *tmp = v;
                    v = PyNumber_Long(v);
                    assert(PyLong_CheckExact(v));
                    Py_DECREF(tmp);
                    if (unlikely(!v)) return (long) -1;
                }
#if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                if (Py_SIZE(x) == 0)
                    return (long) 0;
                is_negative = Py_SIZE(x) < 0;
#else
                {
                    int result = PyObject_RichCompareBool(x, Py_False, Py_LT);
                    if (unlikely(result < 0))
                        return (long) -1;
                    is_negative = result == 1;
                }
#endif
                if (is_unsigned && unlikely(is_negative)) {
                    goto raise_neg_overflow;
                } else if (is_negative) {
                    stepval = PyNumber_Invert(v);
                    if (unlikely(!stepval))
                        return (long) -1;
                } else {
                    stepval = __Pyx_NewRef(v);
                }
                val = (long) 0;
                mask = PyLong_FromLong((1L << chunk_size) - 1); if (unlikely(!mask)) goto done;
                shift = PyLong_FromLong(chunk_size); if (unlikely(!shift)) goto done;
                for (bits = 0; bits < (int) sizeof(long) * 8 - chunk_size; bits += chunk_size) {
                    PyObject *tmp, *digit;
                    digit = PyNumber_And(stepval, mask);
                    if (unlikely(!digit)) goto done;
                    idigit = PyLong_AsLong(digit);
                    Py_DECREF(digit);
                    if (unlikely(idigit < 0)) goto done;
                    tmp = PyNumber_Rshift(stepval, shift);
                    if (unlikely(!tmp)) goto done;
                    Py_DECREF(stepval); stepval = tmp;
                    val |= ((long) idigit) << bits;
                    #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
                    if (Py_SIZE(stepval) == 0)
                        goto unpacking_done;
                    #endif
                }
                idigit = PyLong_AsLong(stepval);
                if (unlikely(idigit < 0)) goto done;
                remaining_bits = ((int) sizeof(long) * 8) - bits - (is_unsigned ? 0 : 1);
                if (unlikely(idigit >= (1L << remaining_bits)))
                    goto raise_overflow;
                val |= ((long) idigit) << bits;
            #if CYTHON_COMPILING_IN_LIMITED_API && PY_VERSION_HEX < 0x030B0000
            unpacking_done:
            #endif
                if (!is_unsigned) {
                    if (unlikely(val & (((long) 1) << (sizeof(long) * 8 - 1))))
                        goto raise_overflow;
                    if (is_negative)
                        val = ~val;
                }
                ret = 0;
            done:
                Py_XDECREF(shift);
                Py_XDECREF(mask);
                Py_XDECREF(stepval);
#endif
                Py_DECREF(v);
                if (likely(!ret))
                    return val;
            }
            return (long) -1;
        }
    } else {
        long val;
        PyObject *tmp = __Pyx_PyNumber_IntOrLong(x);
        if (!tmp) return (long) -1;
        val = __Pyx_PyInt_As_long(tmp);
        Py_DECREF(tmp);
        return val;
    }
raise_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "value too large to convert to long");
    return (long) -1;
raise_neg_overflow:
    PyErr_SetString(PyExc_OverflowError,
        "can't convert negative value to long");
    return (long) -1;
}

/* FastTypeChecks */
#if CYTHON_COMPILING_IN_CPYTHON
static int __Pyx_InBases(PyTypeObject *a, PyTypeObject *b) {
    while (a) {
        a = __Pyx_PyType_GetSlot(a, tp_base, PyTypeObject*);
        if (a == b)
            return 1;
    }
    return b == &PyBaseObject_Type;
}
static CYTHON_INLINE int __Pyx_IsSubtype(PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (a == b) return 1;
    mro = a->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            if (PyTuple_GET_ITEM(mro, i) == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(a, b);
}
static CYTHON_INLINE int __Pyx_IsAnySubtype2(PyTypeObject *cls, PyTypeObject *a, PyTypeObject *b) {
    PyObject *mro;
    if (cls == a || cls == b) return 1;
    mro = cls->tp_mro;
    if (likely(mro)) {
        Py_ssize_t i, n;
        n = PyTuple_GET_SIZE(mro);
        for (i = 0; i < n; i++) {
            PyObject *base = PyTuple_GET_ITEM(mro, i);
            if (base == (PyObject *)a || base == (PyObject *)b)
                return 1;
        }
        return 0;
    }
    return __Pyx_InBases(cls, a) || __Pyx_InBases(cls, b);
}
#if PY_MAJOR_VERSION == 2
static int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject* exc_type2) {
    PyObject *exception, *value, *tb;
    int res;
    __Pyx_PyThreadState_declare
    __Pyx_PyThreadState_assign
    __Pyx_ErrFetch(&exception, &value, &tb);
    res = exc_type1 ? PyObject_IsSubclass(err, exc_type1) : 0;
    if (unlikely(res == -1)) {
        PyErr_WriteUnraisable(err);
        res = 0;
    }
    if (!res) {
        res = PyObject_IsSubclass(err, exc_type2);
        if (unlikely(res == -1)) {
            PyErr_WriteUnraisable(err);
            res = 0;
        }
    }
    __Pyx_ErrRestore(exception, value, tb);
    return res;
}
#else
static CYTHON_INLINE int __Pyx_inner_PyErr_GivenExceptionMatches2(PyObject *err, PyObject* exc_type1, PyObject *exc_type2) {
    if (exc_type1) {
        return __Pyx_IsAnySubtype2((PyTypeObject*)err, (PyTypeObject*)exc_type1, (PyTypeObject*)exc_type2);
    } else {
        return __Pyx_IsSubtype((PyTypeObject*)err, (PyTypeObject*)exc_type2);
    }
}
#endif
static int __Pyx_PyErr_GivenExceptionMatchesTuple(PyObject *exc_type, PyObject *tuple) {
    Py_ssize_t i, n;
    assert(PyExceptionClass_Check(exc_type));
    n = PyTuple_GET_SIZE(tuple);
#if PY_MAJOR_VERSION >= 3
    for (i=0; i<n; i++) {
        if (exc_type == PyTuple_GET_ITEM(tuple, i)) return 1;
    }
#endif
    for (i=0; i<n; i++) {
        PyObject *t = PyTuple_GET_ITEM(tuple, i);
        #if PY_MAJOR_VERSION < 3
        if (likely(exc_type == t)) return 1;
        #endif
        if (likely(PyExceptionClass_Check(t))) {
            if (__Pyx_inner_PyErr_GivenExceptionMatches2(exc_type, NULL, t)) return 1;
        } else {
        }
    }
    return 0;
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches(PyObject *err, PyObject* exc_type) {
    if (likely(err == exc_type)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        if (likely(PyExceptionClass_Check(exc_type))) {
            return __Pyx_inner_PyErr_GivenExceptionMatches2(err, NULL, exc_type);
        } else if (likely(PyTuple_Check(exc_type))) {
            return __Pyx_PyErr_GivenExceptionMatchesTuple(err, exc_type);
        } else {
        }
    }
    return PyErr_GivenExceptionMatches(err, exc_type);
}
static CYTHON_INLINE int __Pyx_PyErr_GivenExceptionMatches2(PyObject *err, PyObject *exc_type1, PyObject *exc_type2) {
    assert(PyExceptionClass_Check(exc_type1));
    assert(PyExceptionClass_Check(exc_type2));
    if (likely(err == exc_type1 || err == exc_type2)) return 1;
    if (likely(PyExceptionClass_Check(err))) {
        return __Pyx_inner_PyErr_GivenExceptionMatches2(err, exc_type1, exc_type2);
    }
    return (PyErr_GivenExceptionMatches(err, exc_type1) || PyErr_GivenExceptionMatches(err, exc_type2));
}
#endif

/* CheckBinaryVersion */
static int __Pyx_check_binary_version(void) {
    char ctversion[5];
    int same=1, i, found_dot;
    const char* rt_from_call = Py_GetVersion();
    PyOS_snprintf(ctversion, 5, "%d.%d", PY_MAJOR_VERSION, PY_MINOR_VERSION);
    found_dot = 0;
    for (i = 0; i < 4; i++) {
        if (!ctversion[i]) {
            same = (rt_from_call[i] < '0' || rt_from_call[i] > '9');
            break;
        }
        if (rt_from_call[i] != ctversion[i]) {
            same = 0;
            break;
        }
    }
    if (!same) {
        char rtversion[5] = {'\0'};
        char message[200];
        for (i=0; i<4; ++i) {
            if (rt_from_call[i] == '.') {
                if (found_dot) break;
                found_dot = 1;
            } else if (rt_from_call[i] < '0' || rt_from_call[i] > '9') {
                break;
            }
            rtversion[i] = rt_from_call[i];
        }
        PyOS_snprintf(message, sizeof(message),
                      "compile time version %s of module '%.100s' "
                      "does not match runtime version %s",
                      ctversion, __Pyx_MODULE_NAME, rtversion);
        return PyErr_WarnEx(NULL, message, 1);
    }
    return 0;
}

/* FunctionExport */
static int __Pyx_ExportFunction(const char *name, void (*f)(void), const char *sig) {
    PyObject *d = 0;
    PyObject *cobj = 0;
    union {
        void (*fp)(void);
        void *p;
    } tmp;
    d = PyObject_GetAttrString(__pyx_m, (char *)"__pyx_capi__");
    if (!d) {
        PyErr_Clear();
        d = PyDict_New();
        if (!d)
            goto bad;
        Py_INCREF(d);
        if (PyModule_AddObject(__pyx_m, (char *)"__pyx_capi__", d) < 0)
            goto bad;
    }
    tmp.fp = f;
    cobj = PyCapsule_New(tmp.p, sig, 0);
    if (!cobj)
        goto bad;
    if (PyDict_SetItemString(d, name, cobj) < 0)
        goto bad;
    Py_DECREF(cobj);
    Py_DECREF(d);
    return 0;
bad:
    Py_XDECREF(cobj);
    Py_XDECREF(d);
    return -1;
}

/* InitStrings */
#if PY_MAJOR_VERSION >= 3
static int __Pyx_InitString(__Pyx_StringTabEntry t, PyObject **str) {
    if (t.is_unicode | t.is_str) {
        if (t.intern) {
            *str = PyUnicode_InternFromString(t.s);
        } else if (t.encoding) {
            *str = PyUnicode_Decode(t.s, t.n - 1, t.encoding, NULL);
        } else {
            *str = PyUnicode_FromStringAndSize(t.s, t.n - 1);
        }
    } else {
        *str = PyBytes_FromStringAndSize(t.s, t.n - 1);
    }
    if (!*str)
        return -1;
    if (PyObject_Hash(*str) == -1)
        return -1;
    return 0;
}
#endif
static int __Pyx_InitStrings(__Pyx_StringTabEntry *t) {
    while (t->p) {
        #if PY_MAJOR_VERSION >= 3
        __Pyx_InitString(*t, t->p);
        #else
        if (t->is_unicode) {
            *t->p = PyUnicode_DecodeUTF8(t->s, t->n - 1, NULL);
        } else if (t->intern) {
            *t->p = PyString_InternFromString(t->s);
        } else {
            *t->p = PyString_FromStringAndSize(t->s, t->n - 1);
        }
        if (!*t->p)
            return -1;
        if (PyObject_Hash(*t->p) == -1)
            return -1;
        #endif
        ++t;
    }
    return 0;
}

static CYTHON_INLINE PyObject* __Pyx_PyUnicode_FromString(const char* c_str) {
    return __Pyx_PyUnicode_FromStringAndSize(c_str, (Py_ssize_t)strlen(c_str));
}
static CYTHON_INLINE const char* __Pyx_PyObject_AsString(PyObject* o) {
    Py_ssize_t ignore;
    return __Pyx_PyObject_AsStringAndSize(o, &ignore);
}
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
#if !CYTHON_PEP393_ENABLED
static const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    char* defenc_c;
    PyObject* defenc = _PyUnicode_AsDefaultEncodedString(o, NULL);
    if (!defenc) return NULL;
    defenc_c = PyBytes_AS_STRING(defenc);
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    {
        char* end = defenc_c + PyBytes_GET_SIZE(defenc);
        char* c;
        for (c = defenc_c; c < end; c++) {
            if ((unsigned char) (*c) >= 128) {
                PyUnicode_AsASCIIString(o);
                return NULL;
            }
        }
    }
#endif
    *length = PyBytes_GET_SIZE(defenc);
    return defenc_c;
}
#else
static CYTHON_INLINE const char* __Pyx_PyUnicode_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
    if (unlikely(__Pyx_PyUnicode_READY(o) == -1)) return NULL;
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
    if (likely(PyUnicode_IS_ASCII(o))) {
        *length = PyUnicode_GET_LENGTH(o);
        return PyUnicode_AsUTF8(o);
    } else {
        PyUnicode_AsASCIIString(o);
        return NULL;
    }
#else
    return PyUnicode_AsUTF8AndSize(o, length);
#endif
}
#endif
#endif
static CYTHON_INLINE const char* __Pyx_PyObject_AsStringAndSize(PyObject* o, Py_ssize_t *length) {
#if __PYX_DEFAULT_STRING_ENCODING_IS_ASCII || __PYX_DEFAULT_STRING_ENCODING_IS_DEFAULT
    if (
#if PY_MAJOR_VERSION < 3 && __PYX_DEFAULT_STRING_ENCODING_IS_ASCII
            __Pyx_sys_getdefaultencoding_not_ascii &&
#endif
            PyUnicode_Check(o)) {
        return __Pyx_PyUnicode_AsStringAndSize(o, length);
    } else
#endif
#if (!CYTHON_COMPILING_IN_PYPY && !CYTHON_COMPILING_IN_LIMITED_API) || (defined(PyByteArray_AS_STRING) && defined(PyByteArray_GET_SIZE))
    if (PyByteArray_Check(o)) {
        *length = PyByteArray_GET_SIZE(o);
        return PyByteArray_AS_STRING(o);
    } else
#endif
    {
        char* result;
        int r = PyBytes_AsStringAndSize(o, &result, length);
        if (unlikely(r < 0)) {
            return NULL;
        } else {
            return result;
        }
    }
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrue(PyObject* x) {
   int is_true = x == Py_True;
   if (is_true | (x == Py_False) | (x == Py_None)) return is_true;
   else return PyObject_IsTrue(x);
}
static CYTHON_INLINE int __Pyx_PyObject_IsTrueAndDecref(PyObject* x) {
    int retval;
    if (unlikely(!x)) return -1;
    retval = __Pyx_PyObject_IsTrue(x);
    Py_DECREF(x);
    return retval;
}
static PyObject* __Pyx_PyNumber_IntOrLongWrongResultType(PyObject* result, const char* type_name) {
    __Pyx_TypeName result_type_name = __Pyx_PyType_GetName(Py_TYPE(result));
#if PY_MAJOR_VERSION >= 3
    if (PyLong_Check(result)) {
        if (PyErr_WarnFormat(PyExc_DeprecationWarning, 1,
                "__int__ returned non-int (type " __Pyx_FMT_TYPENAME ").  "
                "The ability to return an instance of a strict subclass of int is deprecated, "
                "and may be removed in a future version of Python.",
                result_type_name)) {
            __Pyx_DECREF_TypeName(result_type_name);
            Py_DECREF(result);
            return NULL;
        }
        __Pyx_DECREF_TypeName(result_type_name);
        return result;
    }
#endif
    PyErr_Format(PyExc_TypeError,
                 "__%.4s__ returned non-%.4s (type " __Pyx_FMT_TYPENAME ")",
                 type_name, type_name, result_type_name);
    __Pyx_DECREF_TypeName(result_type_name);
    Py_DECREF(result);
    return NULL;
}
static CYTHON_INLINE PyObject* __Pyx_PyNumber_IntOrLong(PyObject* x) {
#if CYTHON_USE_TYPE_SLOTS
  PyNumberMethods *m;
#endif
  const char *name = NULL;
  PyObject *res = NULL;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_Check(x) || PyLong_Check(x)))
#else
  if (likely(PyLong_Check(x)))
#endif
    return __Pyx_NewRef(x);
#if CYTHON_USE_TYPE_SLOTS
  m = Py_TYPE(x)->tp_as_number;
  #if PY_MAJOR_VERSION < 3
  if (m && m->nb_int) {
    name = "int";
    res = m->nb_int(x);
  }
  else if (m && m->nb_long) {
    name = "long";
    res = m->nb_long(x);
  }
  #else
  if (likely(m && m->nb_int)) {
    name = "int";
    res = m->nb_int(x);
  }
  #endif
#else
  if (!PyBytes_CheckExact(x) && !PyUnicode_CheckExact(x)) {
    res = PyNumber_Int(x);
  }
#endif
  if (likely(res)) {
#if PY_MAJOR_VERSION < 3
    if (unlikely(!PyInt_Check(res) && !PyLong_Check(res))) {
#else
    if (unlikely(!PyLong_CheckExact(res))) {
#endif
        return __Pyx_PyNumber_IntOrLongWrongResultType(res, name);
    }
  }
  else if (!PyErr_Occurred()) {
    PyErr_SetString(PyExc_TypeError,
                    "an integer is required");
  }
  return res;
}
static CYTHON_INLINE Py_ssize_t __Pyx_PyIndex_AsSsize_t(PyObject* b) {
  Py_ssize_t ival;
  PyObject *x;
#if PY_MAJOR_VERSION < 3
  if (likely(PyInt_CheckExact(b))) {
    if (sizeof(Py_ssize_t) >= sizeof(long))
        return PyInt_AS_LONG(b);
    else
        return PyInt_AsSsize_t(b);
  }
#endif
  if (likely(PyLong_CheckExact(b))) {
    #if CYTHON_USE_PYLONG_INTERNALS
    if (likely(__Pyx_PyLong_IsCompact(b))) {
        return __Pyx_PyLong_CompactValue(b);
    } else {
      const digit* digits = __Pyx_PyLong_Digits(b);
      const Py_ssize_t size = __Pyx_PyLong_SignedDigitCount(b);
      switch (size) {
         case 2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -2:
           if (8 * sizeof(Py_ssize_t) > 2 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -3:
           if (8 * sizeof(Py_ssize_t) > 3 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case 4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return (Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
         case -4:
           if (8 * sizeof(Py_ssize_t) > 4 * PyLong_SHIFT) {
             return -(Py_ssize_t) (((((((((size_t)digits[3]) << PyLong_SHIFT) | (size_t)digits[2]) << PyLong_SHIFT) | (size_t)digits[1]) << PyLong_SHIFT) | (size_t)digits[0]));
           }
           break;
      }
    }
    #endif
    return PyLong_AsSsize_t(b);
  }
  x = PyNumber_Index(b);
  if (!x) return -1;
  ival = PyInt_AsSsize_t(x);
  Py_DECREF(x);
  return ival;
}
static CYTHON_INLINE Py_hash_t __Pyx_PyIndex_AsHash_t(PyObject* o) {
  if (sizeof(Py_hash_t) == sizeof(Py_ssize_t)) {
    return (Py_hash_t) __Pyx_PyIndex_AsSsize_t(o);
#if PY_MAJOR_VERSION < 3
  } else if (likely(PyInt_CheckExact(o))) {
    return PyInt_AS_LONG(o);
#endif
  } else {
    Py_ssize_t ival;
    PyObject *x;
    x = PyNumber_Index(o);
    if (!x) return -1;
    ival = PyInt_AsLong(x);
    Py_DECREF(x);
    return ival;
  }
}
static CYTHON_INLINE PyObject * __Pyx_PyBool_FromLong(long b) {
  return b ? __Pyx_NewRef(Py_True) : __Pyx_NewRef(Py_False);
}
static CYTHON_INLINE PyObject * __Pyx_PyInt_FromSize_t(size_t ival) {
    return PyInt_FromSize_t(ival);
}


/* #### Code section: utility_code_pragmas_end ### */
#ifdef _MSC_VER
#pragma warning( pop )
#endif



/* #### Code section: end ### */
#endif /* Py_PYTHON_H */
